WO2003041559A3 - Electrical stimulation of the sympathetic nerve chain - Google Patents

Electrical stimulation of the sympathetic nerve chain Download PDF

Info

Publication number
WO2003041559A3
WO2003041559A3 PCT/US2002/034000 US0234000W WO03041559A3 WO 2003041559 A3 WO2003041559 A3 WO 2003041559A3 US 0234000 W US0234000 W US 0234000W WO 03041559 A3 WO03041559 A3 WO 03041559A3
Authority
WO
WIPO (PCT)
Prior art keywords
sympathetic nerve
nerve chain
electrical stimulation
stimulating
effecting
Prior art date
Application number
PCT/US2002/034000
Other languages
French (fr)
Other versions
WO2003041559A2 (en
Inventor
Ali R Rezai
Original Assignee
Cleveland Clinic Foundation
Ali R Rezai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cleveland Clinic Foundation, Ali R Rezai filed Critical Cleveland Clinic Foundation
Priority to JP2003543453A priority Critical patent/JP2005511125A/en
Priority to AU2002340283A priority patent/AU2002340283A1/en
Priority to US10/495,766 priority patent/US7778704B2/en
Publication of WO2003041559A2 publication Critical patent/WO2003041559A2/en
Publication of WO2003041559A3 publication Critical patent/WO2003041559A3/en
Priority to US11/121,006 priority patent/US7877146B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551Spinal or peripheral nerve electrodes
    • A61N1/0553Paddle shaped electrodes, e.g. for laminotomy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0507Electrodes for the digestive system
    • A61N1/0509Stomach and intestinal electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36021External stimulators, e.g. with patch electrodes for treatment of pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071Pain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36017External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin

Abstract

The present invention (Fig. 1) provides a method of effecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of effecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been effected.
PCT/US2002/034000 2000-01-20 2002-10-23 Electrical stimulation of the sympathetic nerve chain WO2003041559A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003543453A JP2005511125A (en) 2001-10-23 2002-10-23 Electrical stimulation of sympathetic nerve chains
AU2002340283A AU2002340283A1 (en) 2001-10-23 2002-10-23 Electrical stimulation of the sympathetic nerve chain
US10/495,766 US7778704B2 (en) 2000-01-20 2002-10-23 Electrical stimulation of the sympathetic nerve chain
US11/121,006 US7877146B2 (en) 2000-01-20 2005-05-04 Methods of treating medical conditions by neuromodulation of the sympathetic nervous system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/001,923 2001-10-23
US10/001,923 US6885888B2 (en) 2000-01-20 2001-10-23 Electrical stimulation of the sympathetic nerve chain

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US10/001,923 Continuation-In-Part US6885888B2 (en) 2000-01-20 2001-10-23 Electrical stimulation of the sympathetic nerve chain

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10495766 A-371-Of-International 2002-10-23
US11/121,006 Continuation-In-Part US7877146B2 (en) 2000-01-20 2005-05-04 Methods of treating medical conditions by neuromodulation of the sympathetic nervous system

Publications (2)

Publication Number Publication Date
WO2003041559A2 WO2003041559A2 (en) 2003-05-22
WO2003041559A3 true WO2003041559A3 (en) 2003-07-10

Family

ID=21698441

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034000 WO2003041559A2 (en) 2000-01-20 2002-10-23 Electrical stimulation of the sympathetic nerve chain

Country Status (4)

Country Link
US (8) US6885888B2 (en)
JP (1) JP2005511125A (en)
AU (1) AU2002340283A1 (en)
WO (1) WO2003041559A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8915741B2 (en) 2003-08-18 2014-12-23 Cardiac Pacemakers, Inc. Sleep quality data collection and evaluation

Families Citing this family (547)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6302875B1 (en) 1996-10-11 2001-10-16 Transvascular, Inc. Catheters and related devices for forming passageways between blood vessels or other anatomical structures
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US20070203531A9 (en) * 1999-12-03 2007-08-30 Medtronic, Inc. Heart rate variability control of gastric electrical stimulator
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
AU6634501A (en) * 2000-06-30 2002-01-14 Sumitomo Pharma Five-membered-ring compound
EP1330287B1 (en) * 2000-10-26 2009-07-29 Medtronic, Inc. Apparatus to minimize the effects of a cardiac insult
US20120108918A1 (en) * 2008-09-19 2012-05-03 Physiosonics, Inc. Acoustic Palpation Using Non-Invasive Ultrasound Techniques for Identification of Target Sites and Assessment of Chronic Pain Disorders
US6907295B2 (en) 2001-08-31 2005-06-14 Biocontrol Medical Ltd. Electrode assembly for nerve control
US6684105B2 (en) * 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US7054686B2 (en) * 2001-08-30 2006-05-30 Biophan Technologies, Inc. Pulsewidth electrical stimulation
US7778703B2 (en) * 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Selective nerve fiber stimulation for treating heart conditions
US7778711B2 (en) * 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US8571653B2 (en) * 2001-08-31 2013-10-29 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US7885709B2 (en) * 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7734355B2 (en) * 2001-08-31 2010-06-08 Bio Control Medical (B.C.M.) Ltd. Treatment of disorders by unidirectional nerve stimulation
US20130178829A1 (en) * 2001-10-23 2013-07-11 Autonomic Technologies, Inc. Methods of treating medical conditions by transvascular neuromodulation of the autonomic nervous system
AU2003210752A1 (en) * 2002-02-01 2003-09-02 The Cleveland Clinic Foundation Modulation of the pain circuitry to affect chronic pain
CA2474950A1 (en) * 2002-02-01 2003-08-07 Ali Rezai Delivery device for stimulating the sympathetic nerve chain
WO2003072135A2 (en) * 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Insitute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
US20090259279A1 (en) * 2002-03-22 2009-10-15 Dobak Iii John D Splanchnic nerve stimulation for treatment of obesity
US7239912B2 (en) * 2002-03-22 2007-07-03 Leptos Biomedical, Inc. Electric modulation of sympathetic nervous system
US7236822B2 (en) * 2002-03-22 2007-06-26 Leptos Biomedical, Inc. Wireless electric modulation of sympathetic nervous system
US7937145B2 (en) * 2002-03-22 2011-05-03 Advanced Neuromodulation Systems, Inc. Dynamic nerve stimulation employing frequency modulation
US7702386B2 (en) * 2002-03-22 2010-04-20 Leptos Biomedical, Inc. Nerve stimulation for treatment of obesity, metabolic syndrome, and Type 2 diabetes
US7551964B2 (en) * 2002-03-22 2009-06-23 Leptos Biomedical, Inc. Splanchnic nerve stimulation for treatment of obesity
US7689276B2 (en) * 2002-09-13 2010-03-30 Leptos Biomedical, Inc. Dynamic nerve stimulation for treatment of disorders
US7689277B2 (en) * 2002-03-22 2010-03-30 Leptos Biomedical, Inc. Neural stimulation for treatment of metabolic syndrome and type 2 diabetes
US8175711B2 (en) 2002-04-08 2012-05-08 Ardian, Inc. Methods for treating a condition or disease associated with cardio-renal function
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US20110207758A1 (en) 2003-04-08 2011-08-25 Medtronic Vascular, Inc. Methods for Therapeutic Renal Denervation
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US6978174B2 (en) 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US7620451B2 (en) * 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US20040039417A1 (en) * 2002-04-16 2004-02-26 Medtronic, Inc. Electrical stimulation and thrombolytic therapy
US7321793B2 (en) * 2003-06-13 2008-01-22 Biocontrol Medical Ltd. Vagal stimulation for atrial fibrillation therapy
US7885711B2 (en) * 2003-06-13 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Vagal stimulation for anti-embolic therapy
US20050065553A1 (en) * 2003-06-13 2005-03-24 Omry Ben Ezra Applications of vagal stimulation
US8204591B2 (en) * 2002-05-23 2012-06-19 Bio Control Medical (B.C.M.) Ltd. Techniques for prevention of atrial fibrillation
US8036745B2 (en) * 2004-06-10 2011-10-11 Bio Control Medical (B.C.M.) Ltd. Parasympathetic pacing therapy during and following a medical procedure, clinical trauma or pathology
WO2003101533A1 (en) * 2002-05-29 2003-12-11 Oklahoma Foundation For Digestive Research Spinal cord stimulation as treatment for functional bowel disorders
US20040082859A1 (en) 2002-07-01 2004-04-29 Alan Schaer Method and apparatus employing ultrasound energy to treat body sphincters
US7657482B1 (en) * 2002-07-15 2010-02-02 Paymentech, L.P. System and apparatus for transaction fraud processing
US7276057B2 (en) * 2002-09-06 2007-10-02 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by drug delivery to the pudendal and sacral nerves
US7328069B2 (en) * 2002-09-06 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves
US7427280B2 (en) * 2002-09-06 2008-09-23 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by delivering drugs to various nerves or tissues
US7328068B2 (en) * 2003-03-31 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by means of electrical stimulation of the pudendal and associated nerves, and the optional delivery of drugs in association therewith
US8880192B2 (en) 2012-04-02 2014-11-04 Bio Control Medical (B.C.M.) Ltd. Electrode cuffs
US7627384B2 (en) 2004-11-15 2009-12-01 Bio Control Medical (B.C.M.) Ltd. Techniques for nerve stimulation
CA2515368A1 (en) * 2003-02-13 2004-08-26 Luciano Rossetti Regulation of food intake and glucose production by modulation of long-chain fatty acyl-coa levels in the hypothalamus
ITMO20030089A1 (en) * 2003-03-28 2004-09-29 Lorenz Biotech Spa ELECTROSTIMULATOR SYSTEM.
US7155278B2 (en) * 2003-04-21 2006-12-26 Medtronic, Inc. Neurostimulation to treat effects of sleep apnea
US7221979B2 (en) * 2003-04-30 2007-05-22 Medtronic, Inc. Methods and apparatus for the regulation of hormone release
US7158826B1 (en) * 2003-04-30 2007-01-02 Pacesetter, Inc. System and method for generating pain inhibition pulses using an implantable cardiac stimulation device
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
US7742818B2 (en) * 2003-05-19 2010-06-22 Medtronic, Inc. Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof
US7620454B2 (en) 2003-05-19 2009-11-17 Medtronic, Inc. Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof
US20080046016A1 (en) * 2003-05-23 2008-02-21 Biocontrol Medical Ltd. Intravascular parasympatheticstimulation for atrial cardioversion
US7107104B2 (en) * 2003-05-30 2006-09-12 Medtronic, Inc. Implantable cortical neural lead and method
US7738952B2 (en) * 2003-06-09 2010-06-15 Palo Alto Investors Treatment of conditions through modulation of the autonomic nervous system
US7149574B2 (en) * 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
WO2005007234A2 (en) * 2003-07-10 2005-01-27 Science Medicus, Inc. Regulation of endocrine and exocrine glands by means of neuro-electrical coded signals
US8606356B2 (en) 2003-09-18 2013-12-10 Cardiac Pacemakers, Inc. Autonomic arousal detection system and method
US20050075702A1 (en) * 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for inhibiting release of pro-inflammatory mediator
US7418292B2 (en) * 2003-10-01 2008-08-26 Medtronic, Inc. Device and method for attenuating an immune response
US20050153885A1 (en) * 2003-10-08 2005-07-14 Yun Anthony J. Treatment of conditions through modulation of the autonomic nervous system
US20050143378A1 (en) 2003-12-29 2005-06-30 Yun Anthony J. Treatment of conditions through pharmacological modulation of the autonomic nervous system
US7657312B2 (en) 2003-11-03 2010-02-02 Cardiac Pacemakers, Inc. Multi-site ventricular pacing therapy with parasympathetic stimulation
US9050469B1 (en) 2003-11-26 2015-06-09 Flint Hills Scientific, Llc Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals
CA2454184A1 (en) * 2003-12-23 2005-06-23 Andres M. Lozano Method and apparatus for treating neurological disorders by electrical stimulation of the brain
US7509166B2 (en) * 2003-12-24 2009-03-24 Cardiac Pacemakers, Inc. Automatic baroreflex modulation responsive to adverse event
EP1711223A1 (en) * 2003-12-24 2006-10-18 Cardiac Pacemakers, Inc. Baroreflex stimulation system
US9020595B2 (en) 2003-12-24 2015-04-28 Cardiac Pacemakers, Inc. Baroreflex activation therapy with conditional shut off
US7869881B2 (en) * 2003-12-24 2011-01-11 Cardiac Pacemakers, Inc. Baroreflex stimulator with integrated pressure sensor
US7647114B2 (en) 2003-12-24 2010-01-12 Cardiac Pacemakers, Inc. Baroreflex modulation based on monitored cardiovascular parameter
US8024050B2 (en) 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US20080015659A1 (en) * 2003-12-24 2008-01-17 Yi Zhang Neurostimulation systems and methods for cardiac conditions
US8126560B2 (en) * 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
WO2005092308A2 (en) 2004-03-25 2005-10-06 The Feinstein Institute For Medical Research Neural tourniquet
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
WO2006007048A2 (en) * 2004-05-04 2006-01-19 The Cleveland Clinic Foundation Methods of treating medical conditions by neuromodulation of the sympathetic nervous system
US7747323B2 (en) 2004-06-08 2010-06-29 Cardiac Pacemakers, Inc. Adaptive baroreflex stimulation therapy for disordered breathing
US20060004413A1 (en) * 2004-06-30 2006-01-05 Peng-Sheng Chen Method and system for the prediction of cardiac arrhythmias
US7725178B2 (en) * 2004-06-30 2010-05-25 Cedars-Sinai Medical Center Method and system for the prediction of cardiac arrhythmias, myocardial ischemia, and other diseased condition of the heart associated with elevated sympathetic neural discharges
US7346382B2 (en) 2004-07-07 2008-03-18 The Cleveland Clinic Foundation Brain stimulation models, systems, devices, and methods
US7664551B2 (en) 2004-07-07 2010-02-16 Medtronic Transneuronix, Inc. Treatment of the autonomic nervous system
US7623924B2 (en) 2004-08-31 2009-11-24 Leptos Biomedical, Inc. Devices and methods for gynecologic hormone modulation in mammals
US9205261B2 (en) 2004-09-08 2015-12-08 The Board Of Trustees Of The Leland Stanford Junior University Neurostimulation methods and systems
US20060052856A1 (en) * 2004-09-08 2006-03-09 Kim Daniel H Stimulation components
US20120277839A1 (en) 2004-09-08 2012-11-01 Kramer Jeffery M Selective stimulation to modulate the sympathetic nervous system
US8521295B2 (en) * 2004-09-23 2013-08-27 Michael D. Laufer Location and deactivation of muscles
WO2006041922A2 (en) * 2004-10-08 2006-04-20 Dara Biosciences, Inc. Agents and methods for administration to the central nervous system
US8676326B1 (en) 2004-10-21 2014-03-18 Pacesetter, Inc Implantable device with responsive vascular and cardiac controllers
US7672733B2 (en) * 2004-10-29 2010-03-02 Medtronic, Inc. Methods and apparatus for sensing cardiac activity via neurological stimulation therapy system or medical electrical lead
US7937143B2 (en) 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
US20070083239A1 (en) * 2005-09-23 2007-04-12 Denise Demarais Methods and apparatus for inducing, monitoring and controlling renal neuromodulation
BRPI0518437A2 (en) 2004-11-16 2008-11-18 Brian Cran lung treatment device and method
US20060116720A1 (en) * 2004-12-01 2006-06-01 Penny Knoblich Method and apparatus for improving renal function
US7366571B2 (en) * 2004-12-10 2008-04-29 Cyberonics, Inc. Neurostimulator with activation based on changes in body temperature
JP2008525102A (en) 2004-12-27 2008-07-17 ノース ショア−ロング アイランド ジューウィッシュ リサーチ インスティテュート Treatment of inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US8600521B2 (en) 2005-01-27 2013-12-03 Cyberonics, Inc. Implantable medical device having multiple electrode/sensor capability and stimulation based on sensed intrinsic activity
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US8260426B2 (en) 2008-01-25 2012-09-04 Cyberonics, Inc. Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US7454245B2 (en) * 2005-01-28 2008-11-18 Cyberonics, Inc. Trained and adaptive response in a neurostimulator
US7561918B2 (en) * 2005-01-28 2009-07-14 Cyberonics, Inc. Autocapture in a neurostimulator
US20060173493A1 (en) * 2005-01-28 2006-08-03 Cyberonics, Inc. Multi-phasic signal for stimulation by an implantable device
US20070060954A1 (en) * 2005-02-25 2007-03-15 Tracy Cameron Method of using spinal cord stimulation to treat neurological disorders or conditions
US8700163B2 (en) 2005-03-04 2014-04-15 Cyberonics, Inc. Cranial nerve stimulation for treatment of substance addiction
US7840266B2 (en) 2005-03-11 2010-11-23 Cardiac Pacemakers, Inc. Integrated lead for applying cardiac resynchronization therapy and neural stimulation therapy
US7587238B2 (en) * 2005-03-11 2009-09-08 Cardiac Pacemakers, Inc. Combined neural stimulation and cardiac resynchronization therapy
US7493161B2 (en) 2005-05-10 2009-02-17 Cardiac Pacemakers, Inc. System and method to deliver therapy in presence of another therapy
US7555341B2 (en) 2005-04-05 2009-06-30 Cardiac Pacemakers, Inc. System to treat AV-conducted ventricular tachyarrhythmia
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US8078275B2 (en) 2005-04-15 2011-12-13 Functional Neuromodulation Inc. Regulation of neurotrophins
US20060286132A1 (en) * 2005-06-16 2006-12-21 Lipov Eugene P Use of stellate ganglion block for the treatment of sexual dysfunction
US20070021803A1 (en) 2005-07-22 2007-01-25 The Foundry Inc. Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction
US20070021786A1 (en) * 2005-07-25 2007-01-25 Cyberonics, Inc. Selective nerve stimulation for the treatment of angina pectoris
US20070027504A1 (en) * 2005-07-27 2007-02-01 Cyberonics, Inc. Cranial nerve stimulation to treat a hearing disorder
US7840280B2 (en) * 2005-07-27 2010-11-23 Cyberonics, Inc. Cranial nerve stimulation to treat a vocal cord disorder
US20070027497A1 (en) * 2005-07-27 2007-02-01 Cyberonics, Inc. Nerve stimulation for treatment of syncope
US7706874B2 (en) 2005-07-28 2010-04-27 Cyberonics, Inc. Stimulating cranial nerve to treat disorders associated with the thyroid gland
US20070027484A1 (en) * 2005-07-28 2007-02-01 Cyberonics, Inc. Autonomic nerve stimulation to treat a pancreatic disorder
US7856273B2 (en) 2005-07-28 2010-12-21 Cyberonics, Inc. Autonomic nerve stimulation to treat a gastrointestinal disorder
US8660647B2 (en) * 2005-07-28 2014-02-25 Cyberonics, Inc. Stimulating cranial nerve to treat pulmonary disorder
US20070027486A1 (en) * 2005-07-29 2007-02-01 Cyberonics, Inc. Medical devices for enhancing intrinsic neural activity
US20070173903A1 (en) * 2005-08-30 2007-07-26 Bioq, Inc. Medical device for restoration of neurological function impaired by peripheral neuropathy
US20070073361A1 (en) * 2005-09-23 2007-03-29 Bioq, Inc. Medical device for restoration of autonomic and immune functions impaired by neuropathy
US20070073354A1 (en) * 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
US8428731B2 (en) * 2005-10-27 2013-04-23 Cyberonics, Inc. Sequenced therapy protocols for an implantable medical device
US8694118B2 (en) * 2005-10-28 2014-04-08 Cyberonics, Inc. Variable output ramping for an implantable medical device
US20070100377A1 (en) * 2005-10-28 2007-05-03 Cyberonics, Inc. Providing multiple signal modes for a medical device
US7957796B2 (en) 2005-10-28 2011-06-07 Cyberonics, Inc. Using physiological sensor data with an implantable medical device
US10716749B2 (en) * 2005-11-03 2020-07-21 Palo Alto Investors Methods and compositions for treating a renal disease condition in a subject
US8812112B2 (en) * 2005-11-10 2014-08-19 ElectroCore, LLC Electrical treatment of bronchial constriction
US20070106337A1 (en) * 2005-11-10 2007-05-10 Electrocore, Inc. Methods And Apparatus For Treating Disorders Through Neurological And/Or Muscular Intervention
EP1948301B8 (en) * 2005-11-10 2014-03-12 ElectroCore LLC Electrical stimulation treatment of bronchial constriction
US7725188B2 (en) * 2006-02-10 2010-05-25 Electrocore Llc Electrical stimulation treatment of hypotension
US20090234417A1 (en) * 2005-11-10 2009-09-17 Electrocore, Inc. Methods And Apparatus For The Treatment Of Metabolic Disorders
US20110125203A1 (en) * 2009-03-20 2011-05-26 ElectroCore, LLC. Magnetic Stimulation Devices and Methods of Therapy
US8041428B2 (en) 2006-02-10 2011-10-18 Electrocore Llc Electrical stimulation treatment of hypotension
US9037247B2 (en) 2005-11-10 2015-05-19 ElectroCore, LLC Non-invasive treatment of bronchial constriction
US7822474B2 (en) * 2005-11-30 2010-10-26 Cedars-Sinai Medical Center Methods for the prediction of arrhythmias and prevention of sudden cardiac death
US7570999B2 (en) 2005-12-20 2009-08-04 Cardiac Pacemakers, Inc. Implantable device for treating epilepsy and cardiac rhythm disorders
US9566447B2 (en) * 2005-12-28 2017-02-14 Cardiac Pacemakers, Inc. Neural stimulation system for reducing atrial proarrhythmia
US20070156200A1 (en) * 2005-12-29 2007-07-05 Lilian Kornet System and method for regulating blood pressure and electrolyte balance
US7996079B2 (en) 2006-01-24 2011-08-09 Cyberonics, Inc. Input response override for an implantable medical device
US7657310B2 (en) 2006-01-26 2010-02-02 Cyberonics, Inc. Treatment of reproductive endocrine disorders by vagus nerve stimulation
US7801601B2 (en) 2006-01-27 2010-09-21 Cyberonics, Inc. Controlling neuromodulation using stimulus modalities
US7711430B2 (en) * 2006-02-10 2010-05-04 Electrocore Llc Methods and apparatus for treating anaphylaxis using electrical modulation
US20070191904A1 (en) * 2006-02-14 2007-08-16 Imad Libbus Expandable stimulation electrode with integrated pressure sensor and methods related thereto
WO2007115118A1 (en) 2006-03-29 2007-10-11 Catholic Healthcare West Vagus nerve stimulation method
EP2030210A4 (en) * 2006-04-12 2010-04-14 Proteus Biomedical Inc Void-free implantable hermetically sealed structures
US8401650B2 (en) * 2008-04-10 2013-03-19 Electrocore Llc Methods and apparatus for electrical treatment using balloon and electrode
US20100057178A1 (en) * 2006-04-18 2010-03-04 Electrocore, Inc. Methods and apparatus for spinal cord stimulation using expandable electrode
US20090157138A1 (en) * 2006-04-18 2009-06-18 Electrocore, Inc. Methods And Apparatus For Treating Ileus Condition Using Electrical Signals
US8209034B2 (en) * 2008-12-18 2012-06-26 Electrocore Llc Methods and apparatus for electrical stimulation treatment using esophageal balloon and electrode
US20100241188A1 (en) * 2009-03-20 2010-09-23 Electrocore, Inc. Percutaneous Electrical Treatment Of Tissue
US7962220B2 (en) 2006-04-28 2011-06-14 Cyberonics, Inc. Compensation reduction in tissue stimulation therapy
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US8295926B2 (en) 2006-06-02 2012-10-23 Advanced Neuromodulation Systems, Inc. Dynamic nerve stimulation in combination with other eating disorder treatment modalities
US7647101B2 (en) * 2006-06-09 2010-01-12 Cardiac Pacemakers, Inc. Physical conditioning system, device and method
US20070299476A1 (en) * 2006-06-23 2007-12-27 Euljoon Park Sympathetic afferent activation for adjusting autonomic tone
EP2465574B1 (en) 2006-06-28 2015-10-28 Ardian, Inc. Systems for thermally-induced renal neuromodulation
US8170668B2 (en) 2006-07-14 2012-05-01 Cardiac Pacemakers, Inc. Baroreflex sensitivity monitoring and trending for tachyarrhythmia detection and therapy
US8457734B2 (en) 2006-08-29 2013-06-04 Cardiac Pacemakers, Inc. System and method for neural stimulation
US7801604B2 (en) * 2006-08-29 2010-09-21 Cardiac Pacemakers, Inc. Controlled titration of neurostimulation therapy
US7769443B2 (en) * 2006-09-06 2010-08-03 Giancarlo Barolat Implantable reel for coiling an implantable elongated member
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
CA2668098A1 (en) * 2006-11-03 2008-05-15 Gep Technology, Inc. Apparatus and methods for minimally invasive obesity treatment
US7993323B2 (en) 2006-11-13 2011-08-09 Uptake Medical Corp. High pressure and high temperature vapor catheters and systems
US20100191302A1 (en) * 2006-12-01 2010-07-29 Board Of Regents, University Of Texas System Gastrointestinal electrical stimulation for the treatment of visceral pain
US9314618B2 (en) 2006-12-06 2016-04-19 Spinal Modulation, Inc. Implantable flexible circuit leads and methods of use
JP5414531B2 (en) 2006-12-06 2014-02-12 スパイナル・モデュレーション・インコーポレイテッド Delivery device and systems and methods for stimulating neural tissue at multiple spinal levels
EP2099374A4 (en) 2006-12-06 2012-10-03 Spinal Modulation Inc Hard tissue anchors and delivery devices
WO2008070808A2 (en) 2006-12-06 2008-06-12 Spinal Modulation, Inc. Expandable stimulation leads and methods of use
US20100217347A1 (en) * 2006-12-16 2010-08-26 Greatbatch, Inc. Neurostimulation for the treatment of pulmonary disorders
US20080183248A1 (en) * 2007-01-17 2008-07-31 The Cleveland Clinic Foundation Apparatus and methods for treating pulmonary conditions
US8554337B2 (en) * 2007-01-25 2013-10-08 Giancarlo Barolat Electrode paddle for neurostimulation
US7706875B2 (en) * 2007-01-25 2010-04-27 Cyberonics, Inc. Modulation of drug effects by vagus nerve stimulation
CA2877177C (en) 2007-01-29 2018-05-22 Simon Fraser University Transvascular nerve stimulation apparatus and methods
AU2008210504B2 (en) 2007-01-29 2012-07-26 Spinal Modulation, Inc. Sutureless lead retention features
US8068918B2 (en) * 2007-03-09 2011-11-29 Enteromedics Inc. Remote monitoring and control of implantable devices
EP2129352B1 (en) * 2007-03-13 2016-03-09 The Feinstein Institute for Medical Research Treatment of inflammation by non-invasive stimulation
AT505042B1 (en) * 2007-03-21 2009-11-15 Med El Elektromed Geraete Gmbh SYSTEM FOR ELECTROSTIMULATION
US20080249584A1 (en) * 2007-04-05 2008-10-09 Cardiac Pacemakers, Inc. Method and device for cardiosympathetic inhibition
US7869884B2 (en) 2007-04-26 2011-01-11 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US7904175B2 (en) 2007-04-26 2011-03-08 Cyberonics, Inc. Trans-esophageal vagus nerve stimulation
US7962214B2 (en) 2007-04-26 2011-06-14 Cyberonics, Inc. Non-surgical device and methods for trans-esophageal vagus nerve stimulation
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
US8549015B2 (en) 2007-05-01 2013-10-01 Giancarlo Barolat Method and system for distinguishing nociceptive pain from neuropathic pain
US20080281365A1 (en) * 2007-05-09 2008-11-13 Tweden Katherine S Neural signal duty cycle
US8983609B2 (en) 2007-05-30 2015-03-17 The Cleveland Clinic Foundation Apparatus and method for treating pulmonary conditions
PA8781801A1 (en) * 2007-05-30 2009-01-23 Wyeth Corp ANTIDEPRESSIVE HETEROARILO DERIVATIVES OF BENZODIOXANOS HETEROCICLO-FUSIONADOS
US20080300657A1 (en) * 2007-05-31 2008-12-04 Mark Raymond Stultz Therapy system
US7881784B2 (en) * 2007-06-14 2011-02-01 The Board Of Regents Of The University Of Texas System Hepatic electrical stimulation
US20090118777A1 (en) * 2007-08-09 2009-05-07 Kobi Iki Efferent and afferent splanchnic nerve stimulation
US8391970B2 (en) 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
CL2008002675A1 (en) * 2007-09-11 2008-11-07 Wyeth Corp Mycoplasma gallisepticum attenuated bacterium; vaccine composition that comprises it; vaccination method; and method of identification of attenuated mycoplasma gallisepticum clones.
BRPI0817271A2 (en) * 2007-09-26 2015-06-16 Univ Duke Method of treating Parkinson's disease and other related disorders
US8214057B2 (en) 2007-10-16 2012-07-03 Giancarlo Barolat Surgically implantable electrodes
US8322335B2 (en) 2007-10-22 2012-12-04 Uptake Medical Corp. Determining patient-specific vapor treatment and delivery parameters
US8731665B1 (en) 2007-10-24 2014-05-20 Pacesetter, Inc. Posture detection using pressure and other physiologic sensors
US20090204173A1 (en) 2007-11-05 2009-08-13 Zi-Ping Fang Multi-Frequency Neural Treatments and Associated Systems and Methods
WO2009070697A2 (en) * 2007-11-26 2009-06-04 Micro Transponder Inc. Implantable transponder systems and methods
US8457757B2 (en) * 2007-11-26 2013-06-04 Micro Transponder, Inc. Implantable transponder systems and methods
US9089707B2 (en) 2008-07-02 2015-07-28 The Board Of Regents, The University Of Texas System Systems, methods and devices for paired plasticity
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
US8989858B2 (en) * 2007-12-05 2015-03-24 The Invention Science Fund I, Llc Implant system for chemical modulation of neural activity
US8170659B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc Method for thermal modulation of neural activity
US8170658B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US20090149799A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for chemical modulation of neural activity
US8180446B2 (en) * 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8165669B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US20090149797A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware System for reversible chemical modulation of neural activity
US8165668B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8180447B2 (en) 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method for reversible chemical modulation of neural activity
US8337404B2 (en) 2010-10-01 2012-12-25 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8571643B2 (en) 2010-09-16 2013-10-29 Flint Hills Scientific, Llc Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8382667B2 (en) 2010-10-01 2013-02-26 Flint Hills Scientific, Llc Detecting, quantifying, and/or classifying seizures using multimodal data
US8676322B2 (en) * 2008-01-30 2014-03-18 Boston Scientific Neuromodulation Corporation Methods and systems of treating pancreatitis pain
US9220889B2 (en) 2008-02-11 2015-12-29 Intelect Medical, Inc. Directional electrode devices with locating features
US8019440B2 (en) 2008-02-12 2011-09-13 Intelect Medical, Inc. Directional lead assembly
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
WO2009146030A1 (en) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
EP2300099A1 (en) 2008-04-04 2011-03-30 Enteromedics Inc. Methods and systems for glucose regulation
US8682449B2 (en) 2008-04-10 2014-03-25 ElectroCore, LLC Methods and apparatus for transcranial stimulation
US8543211B2 (en) 2008-04-10 2013-09-24 ElectroCore, LLC Methods and apparatus for deep brain stimulation
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
US20090275996A1 (en) * 2008-04-30 2009-11-05 Medtronic, Inc. Techniques for placing medical leads for electrical stimulation of nerve tissue
US20090275997A1 (en) * 2008-05-01 2009-11-05 Michael Allen Faltys Vagus nerve stimulation electrodes and methods of use
US8473062B2 (en) * 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
WO2009137819A1 (en) 2008-05-09 2009-11-12 Innovative Pulmonary Solutions, Inc. Systems, assemblies, and methods for treating a bronchial tree
US9272153B2 (en) 2008-05-15 2016-03-01 Boston Scientific Neuromodulation Corporation VOA generation system and method using a fiber specific analysis
KR100989452B1 (en) 2008-06-24 2010-10-26 (주)신화라이팅 LED lighting apparatus
WO2010006341A1 (en) 2008-07-11 2010-01-14 Gep Technology, Inc. Apparatus and methods for minimally invasive obesity treatment
US7941227B2 (en) * 2008-09-03 2011-05-10 Boston Scientific Neuromodulation Corporation Implantable electric stimulation system and methods of making and using
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
EP2334234A4 (en) 2008-09-19 2013-03-20 Tandem Diabetes Care Inc Solute concentration measurement device and related methods
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
US8417344B2 (en) 2008-10-24 2013-04-09 Cyberonics, Inc. Dynamic cranial nerve stimulation based on brain state determination from cardiac data
EP3202457B1 (en) 2008-10-27 2020-05-27 Spinal Modulation Inc. Selective stimulation systems and signal parameters for medical conditions
US8688210B2 (en) * 2008-10-31 2014-04-01 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US8260412B2 (en) 2008-10-31 2012-09-04 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US9597505B2 (en) * 2008-10-31 2017-03-21 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US8560060B2 (en) 2008-10-31 2013-10-15 Medtronic, Inc. Isolation of sensing and stimulation circuitry
WO2010051500A1 (en) * 2008-10-31 2010-05-06 Medtronic, Inc. Therapy system including cardiac rhythm therapy and neurostimulation capabilities
US8774918B2 (en) * 2008-10-31 2014-07-08 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US8498698B2 (en) 2008-10-31 2013-07-30 Medtronic, Inc. Isolation of sensing and stimulation circuitry
US8005539B2 (en) * 2008-10-31 2011-08-23 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US8611996B2 (en) 2008-10-31 2013-12-17 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US8249708B2 (en) * 2008-10-31 2012-08-21 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
EP2367596A1 (en) * 2008-10-31 2011-09-28 Medtronic, Inc. Shunt-current reduction housing for an implantable therapy system
US9192769B2 (en) * 2008-10-31 2015-11-24 Medtronic, Inc. Shunt-current reduction techniques for an implantable therapy system
US8452394B2 (en) 2008-10-31 2013-05-28 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US8532779B2 (en) * 2008-10-31 2013-09-10 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US9775987B2 (en) 2008-10-31 2017-10-03 Medtronic, Inc. Implantable medical device crosstalk evaluation and mitigation
US9327121B2 (en) 2011-09-08 2016-05-03 Nevro Corporation Selective high frequency spinal cord modulation for inhibiting pain, including cephalic and/or total body pain with reduced side effects, and associated systems and methods
US8255057B2 (en) 2009-01-29 2012-08-28 Nevro Corporation Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
WO2010059617A2 (en) 2008-11-18 2010-05-27 Setpoint Medical Corporation Devices and methods for optimizing electrode placement for anti-inflamatory stimulation
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8808345B2 (en) 2008-12-31 2014-08-19 Medtronic Ardian Luxembourg S.A.R.L. Handle assemblies for intravascular treatment devices and associated systems and methods
EP2376011B1 (en) 2009-01-09 2019-07-03 ReCor Medical, Inc. Apparatus for treatment of mitral valve insufficiency
US8494641B2 (en) * 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US9320908B2 (en) * 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US20100185249A1 (en) * 2009-01-22 2010-07-22 Wingeier Brett M Method and Devices for Adrenal Stimulation
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
US8870773B2 (en) * 2009-02-09 2014-10-28 The Cleveland Clinic Foundation Ultrasound-guided delivery of a therapy delivery device to a nerve target
US20100268297A1 (en) * 2009-02-24 2010-10-21 Hans Neisz Duodenal Stimulation To Induce Satiety
AU2010229985B2 (en) 2009-03-24 2015-09-17 Spinal Modulation, Inc. Pain management with stimulation subthreshold to paresthesia
US8326426B2 (en) * 2009-04-03 2012-12-04 Enteromedics, Inc. Implantable device with heat storage
US8321030B2 (en) 2009-04-20 2012-11-27 Advanced Neuromodulation Systems, Inc. Esophageal activity modulated obesity therapy
DE202010018338U1 (en) 2009-04-22 2015-10-12 Nevro Corporation Spinal cord modulation system for the relief of chronic pain
EP2756864B1 (en) 2009-04-22 2023-03-15 Nevro Corporation Spinal cord modulation systems for inducing paresthetic and anesthetic effects
US8239028B2 (en) * 2009-04-24 2012-08-07 Cyberonics, Inc. Use of cardiac parameters in methods and systems for treating a chronic medical condition
US8827912B2 (en) 2009-04-24 2014-09-09 Cyberonics, Inc. Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8340772B2 (en) 2009-05-08 2012-12-25 Advanced Neuromodulation Systems, Inc. Brown adipose tissue utilization through neuromodulation
US9259569B2 (en) 2009-05-15 2016-02-16 Daniel M. Brounstein Methods, systems and devices for neuromodulating spinal anatomy
AU2010258792B2 (en) 2009-06-09 2015-07-02 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US9386927B2 (en) * 2009-07-28 2016-07-12 Medtronic, Inc. Implantable blood pressure monitor
US8498710B2 (en) 2009-07-28 2013-07-30 Nevro Corporation Linked area parameter adjustment for spinal cord stimulation and associated systems and methods
CA2921304C (en) 2009-07-30 2018-06-05 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
JP5734295B2 (en) 2009-08-27 2015-06-17 ザ クリーブランド クリニック ファウンデーション System and method for estimating a site of tissue activity
WO2011056684A2 (en) 2009-10-27 2011-05-12 Innovative Pulmonary Solutions, Inc. Delivery devices with coolable energy emitting assemblies
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
KR101820542B1 (en) 2009-11-11 2018-01-19 호라이라 인코포레이티드 Systems, apparatuses, and methods for treating tissue and controlling stenosis
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
WO2011068997A1 (en) 2009-12-02 2011-06-09 The Cleveland Clinic Foundation Reversing cognitive-motor impairments in patients having a neuro-degenerative disease using a computational modeling approach to deep brain stimulation programming
WO2011079309A2 (en) 2009-12-23 2011-06-30 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
US20110208175A1 (en) * 2010-02-24 2011-08-25 Medtronic Vascular, Inc. Methods for Treating Sleep Apnea Via Renal Denervation
US8556891B2 (en) 2010-03-03 2013-10-15 Medtronic Ablation Frontiers Llc Variable-output radiofrequency ablation power supply
US8870863B2 (en) 2010-04-26 2014-10-28 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
US8831732B2 (en) 2010-04-29 2014-09-09 Cyberonics, Inc. Method, apparatus and system for validating and quantifying cardiac beat data quality
US8649871B2 (en) 2010-04-29 2014-02-11 Cyberonics, Inc. Validity test adaptive constraint modification for cardiac data used for detection of state changes
US8562536B2 (en) 2010-04-29 2013-10-22 Flint Hills Scientific, Llc Algorithm for detecting a seizure from cardiac data
EP2568904B1 (en) 2010-05-10 2019-10-02 Spinal Modulation Inc. Device for reducing migration
JP5830090B2 (en) 2010-06-14 2015-12-09 ボストン サイエンティフィック ニューロモデュレイション コーポレイション Programming interface for spinal nerve regulation
US8679009B2 (en) 2010-06-15 2014-03-25 Flint Hills Scientific, Llc Systems approach to comorbidity assessment
US8641646B2 (en) 2010-07-30 2014-02-04 Cyberonics, Inc. Seizure detection using coordinate data
CN103547229B (en) 2010-08-05 2017-09-26 美敦力Af卢森堡有限责任公司 Cryogenic ablation device, the system and method modulated for renal nerve
WO2012149511A2 (en) 2011-04-28 2012-11-01 Synecor Llc Neuromodulation systems and methods for treating acute heart failure syndromes
US8684921B2 (en) 2010-10-01 2014-04-01 Flint Hills Scientific Llc Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis
US9084610B2 (en) 2010-10-21 2015-07-21 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses, systems, and methods for renal neuromodulation
EP3100696B1 (en) 2010-10-25 2023-01-11 Medtronic Ardian Luxembourg S.à.r.l. Catheter apparatuses having multi-electrode arrays for renal neuromodulation
TW201221174A (en) 2010-10-25 2012-06-01 Medtronic Ardian Luxembourg Microwave catheter apparatuses, systems, and methods for renal neuromodulation
JP6046041B2 (en) 2010-10-25 2016-12-14 メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ Devices, systems, and methods for neuromodulation therapy evaluation and feedback
US9060754B2 (en) 2010-10-26 2015-06-23 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation cryotherapeutic devices and associated systems and methods
US9060755B2 (en) 2010-10-26 2015-06-23 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation cryotherapeutic devices and associated systems and methods
US20120123293A1 (en) * 2010-11-11 2012-05-17 IINN, Inc. Motor nerve root stimulation
US9821159B2 (en) 2010-11-16 2017-11-21 The Board Of Trustees Of The Leland Stanford Junior University Stimulation devices and methods
RU2013127313A (en) 2010-11-16 2014-12-27 Те Борд Оф Трастиз Оф Те Лилэнд Стэнфорд Джуниор Юниверсити SYSTEMS AND METHODS FOR TREATING A DRY EYE
US10292754B2 (en) 2010-11-17 2019-05-21 Medtronic Ardian Luxembourg S.A.R.L. Therapeutic renal neuromodulation for treating dyspnea and associated systems and methods
WO2012075198A2 (en) 2010-11-30 2012-06-07 Nevro Corporation Extended pain relief via high frequency spinal cord modulation, and associated systems and methods
AU2012212150B2 (en) 2011-02-02 2016-09-29 Spinal Modulation, Inc Devices, systems and methods for the targeted treatment of movement disorders
US9789313B2 (en) 2011-02-23 2017-10-17 John D. LIPANI System and methods for diagnosis and treatment of discogenic lower back pain
US9504390B2 (en) 2011-03-04 2016-11-29 Globalfoundries Inc. Detecting, assessing and managing a risk of death in epilepsy
EP2688642B1 (en) * 2011-03-24 2022-05-11 California Institute of Technology Neurostimulator
JP2014513622A (en) 2011-03-29 2014-06-05 ボストン サイエンティフィック ニューロモデュレイション コーポレイション Communication interface for therapeutic stimulus delivery system
CA2832311A1 (en) 2011-04-08 2012-11-29 Covidien Lp Iontophoresis drug delivery system and method for denervation of the renal sympathetic nerve and iontophoretic drug delivery
US8725239B2 (en) 2011-04-25 2014-05-13 Cyberonics, Inc. Identifying seizures using heart rate decrease
CN103930061B (en) 2011-04-25 2016-09-14 美敦力阿迪安卢森堡有限责任公司 Relevant low temperature sacculus for restricted conduit wall cryogenic ablation limits the device and method disposed
US9402550B2 (en) 2011-04-29 2016-08-02 Cybertronics, Inc. Dynamic heart rate threshold for neurological event detection
CN103619405B (en) 2011-05-09 2015-11-25 赛博恩特医疗器械公司 The individual pulse being used for the treatment of the cholinergic anti-inflammatory pathway of chronic inflammatory disease activates
US9592389B2 (en) 2011-05-27 2017-03-14 Boston Scientific Neuromodulation Corporation Visualization of relevant stimulation leadwire electrodes relative to selected stimulation information
US20130072995A1 (en) 2011-07-11 2013-03-21 Terrance Ransbury Catheter system for acute neuromodulation
EP2731671B1 (en) 2011-07-11 2019-04-03 Interventional Autonomics Corporation Catheter system for acute neuromodulation
US9446240B2 (en) 2011-07-11 2016-09-20 Interventional Autonomics Corporation System and method for neuromodulation
AU2012294364A1 (en) 2011-08-09 2014-03-20 Boston Scientific Neuromodulation Corporation Remote control for blind clinical trials of electrical stimulation
US10206591B2 (en) 2011-10-14 2019-02-19 Flint Hills Scientific, Llc Seizure detection methods, apparatus, and systems using an autoregression algorithm
CN104125799A (en) 2011-11-07 2014-10-29 美敦力阿迪安卢森堡有限责任公司 Endovascular nerve monitoring devices and associated systems and methods
US9192766B2 (en) 2011-12-02 2015-11-24 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation methods and devices for treatment of polycystic kidney disease
EP2788078B1 (en) 2011-12-09 2020-09-02 Metavention, Inc. Therapeutic neuromodulation of the hepatic system
US8886311B2 (en) * 2012-01-27 2014-11-11 Medtronic, Inc. Techniques for mitigating motion artifacts from implantable physiological sensors
EP2822645B1 (en) 2012-03-05 2017-05-03 Simon Fraser University Transvascular nerve stimulation apparatus
AU2013230883A1 (en) 2012-03-07 2014-09-11 Medtronic Af Luxembourg S.A.R.L. Selective modulation of renal nerves
US9750568B2 (en) 2012-03-08 2017-09-05 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
AU2013230774B2 (en) 2012-03-08 2015-12-03 Medtronic Af Luxembourg S.A.R.L. Gastrointestinal neuromodulation and associated systems and methods
WO2013134472A1 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg S.A.R.L. Renal neuromodulation methods and systems for treatment of hyperaldosteronism
CA2865242A1 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg S.A.R.L. Biomarker sampling in the context of neuromodulation devices and associated systems and methods
US20150065945A1 (en) * 2012-03-08 2015-03-05 Denise Zarins Spinal neuromodulation and associated systems and methods
AU2013230893B2 (en) 2012-03-08 2015-12-03 Medtronic Af Luxembourg S.A.R.L. Neuromodulation and associated systems and methods for the management of pain
AU2013230906A1 (en) 2012-03-08 2014-09-18 Medtronic Af Luxembourg S.A.R.L. Neuromodulation and associated systems and methods for the treatment of sexual dysfunction
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US8676331B2 (en) 2012-04-02 2014-03-18 Nevro Corporation Devices for controlling spinal cord modulation for inhibiting pain, and associated systems and methods, including controllers for automated parameter selection
US9126055B2 (en) 2012-04-20 2015-09-08 Cardiac Science Corporation AED faster time to shock method and device
US10448839B2 (en) 2012-04-23 2019-10-22 Livanova Usa, Inc. Methods, systems and apparatuses for detecting increased risk of sudden death
US10258791B2 (en) 2012-04-27 2019-04-16 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies for neuromodulation proximate a bifurcation of a renal artery and associated systems and methods
US9241752B2 (en) 2012-04-27 2016-01-26 Medtronic Ardian Luxembourg S.A.R.L. Shafts with pressure relief in cryotherapeutic catheters and associated devices, systems, and methods
US9943354B2 (en) 2012-04-27 2018-04-17 Medtronic Ardian Luxembourg S.A.R.L. Methods and devices for localized inhibition of inflammation by ablation
US9848950B2 (en) 2012-04-27 2017-12-26 Medtronic Ardian Luxembourg S.A.R.L. Methods and devices for localized disease treatment by ablation
WO2013162700A1 (en) 2012-04-27 2013-10-31 Medtronic Ardian Luxembourg Sarl Cryotherapeutic devices for renal neuromodulation and associated systems and methods
US20130331813A1 (en) * 2012-05-02 2013-12-12 Enigma Medical, Inc. System and method of trans-abdominal pre-aortic ganglion ablation
CA2872189A1 (en) 2012-05-11 2013-11-14 William W. CHANG Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US9555186B2 (en) 2012-06-05 2017-01-31 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
EP4233953A3 (en) 2012-06-21 2023-11-01 Lungpacer Medical Inc. Transvascular diaphragm pacing systems
US9833614B1 (en) 2012-06-22 2017-12-05 Nevro Corp. Autonomic nervous system control via high frequency spinal cord modulation, and associated systems and methods
US8951296B2 (en) 2012-06-29 2015-02-10 Medtronic Ardian Luxembourg S.A.R.L. Devices and methods for photodynamically modulating neural function in a human
EP2879757B1 (en) 2012-08-04 2019-06-26 Boston Scientific Neuromodulation Corporation Systems and methods for storing and transferring registration, atlas, and lead information between medical devices
WO2014035966A1 (en) * 2012-08-28 2014-03-06 Ohio State Innovation Foundation Devices, systems, and methods for treating circadian rhythm disorders
EP2891091B1 (en) 2012-08-28 2018-01-31 Boston Scientific Neuromodulation Corporation Capture and visualization of clinical effects data in relation to a lead and/or locus of stimulation
US8612022B1 (en) 2012-09-13 2013-12-17 Invatec S.P.A. Neuromodulation catheters and associated systems and methods
EP2900317B1 (en) 2012-09-19 2019-06-12 Ohio State Innovation Foundation Apparatus for treating body organ aging
RU2515406C1 (en) * 2012-10-02 2014-05-10 Федеральное государственное бюджетное учреждение "Пятигорский государственный научно-исследовательский институт курортологии Федерального медико-биологического агентства" (ФГБУ ПГНИИК ФМБА России) Method for rehabilitation treatment of patients with chronic pancreatitis in workers occupied in harmful working conditions
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
US9044575B2 (en) 2012-10-22 2015-06-02 Medtronic Adrian Luxembourg S.a.r.l. Catheters with enhanced flexibility and associated devices, systems, and methods
CN104968287B (en) 2012-10-22 2018-05-22 美敦力Af卢森堡有限责任公司 Flexible conduit with improvement
US9792412B2 (en) 2012-11-01 2017-10-17 Boston Scientific Neuromodulation Corporation Systems and methods for VOA model generation and use
US9095321B2 (en) 2012-11-21 2015-08-04 Medtronic Ardian Luxembourg S.A.R.L. Cryotherapeutic devices having integral multi-helical balloons and methods of making the same
US9364671B2 (en) * 2012-11-28 2016-06-14 Autonomic Technologies, Inc. Neuromodulation to treat menopause-related conditions
US9017317B2 (en) 2012-12-06 2015-04-28 Medtronic Ardian Luxembourg S.A.R.L. Refrigerant supply system for cryotherapy including refrigerant recompression and associated devices, systems, and methods
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
US10220211B2 (en) 2013-01-22 2019-03-05 Livanova Usa, Inc. Methods and systems to diagnose depression
CN104936511B (en) 2013-01-24 2018-01-16 泰勒顿国际控股公司 Body structure is imaged
WO2014138709A1 (en) 2013-03-08 2014-09-12 Oculeve, Inc. Devices and methods for treating dry eye in animals
US9717627B2 (en) 2013-03-12 2017-08-01 Oculeve, Inc. Implant delivery devices, systems, and methods
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
US9066726B2 (en) 2013-03-15 2015-06-30 Medtronic Ardian Luxembourg S.A.R.L. Multi-electrode apposition judgment using pressure elements
EP2968919B1 (en) 2013-03-15 2021-08-25 Medtronic Ardian Luxembourg S.à.r.l. Controlled neuromodulation systems
US9179974B2 (en) 2013-03-15 2015-11-10 Medtronic Ardian Luxembourg S.A.R.L. Helical push wire electrode
US9370660B2 (en) 2013-03-29 2016-06-21 Rainbow Medical Ltd. Independently-controlled bidirectional nerve stimulation
NZ704579A (en) 2013-04-19 2018-10-26 Oculeve Inc Nasal stimulation devices and methods
EP2996754B1 (en) 2013-05-18 2023-04-26 Medtronic Ardian Luxembourg S.à.r.l. Neuromodulation catheters with shafts for enhanced flexibility and control and associated devices and systems
US9895539B1 (en) 2013-06-10 2018-02-20 Nevro Corp. Methods and systems for disease treatment using electrical stimulation
US20140369969A1 (en) * 2013-06-13 2014-12-18 Palo Alto Investors Methods for treating conditions by restoring central nervous system endocrine gland function, and compositions and devices for practicing the same
US9559594B2 (en) * 2013-06-24 2017-01-31 Covidien Lp Dead-time optimization of resonant inverters
CN105531591B (en) * 2013-08-09 2018-08-10 加利福尼亚大学董事会 Digital fluid sample separation equipment and the method for quantifying sample analysis for a step
US9339332B2 (en) 2013-08-30 2016-05-17 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters with nerve monitoring features for transmitting digital neural signals and associated systems and methods
US9326816B2 (en) 2013-08-30 2016-05-03 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation systems having nerve monitoring assemblies and associated devices, systems, and methods
US9433796B2 (en) * 2013-09-03 2016-09-06 Boston Scientific Neuromodulation Corporation Medical device application for an external device using data logged at an implantable medical device
US10052495B2 (en) 2013-09-08 2018-08-21 Tylerton International Inc. Detection of reduced-control cardiac zones
US20150073515A1 (en) 2013-09-09 2015-03-12 Medtronic Ardian Luxembourg S.a.r.I. Neuromodulation Catheter Devices and Systems Having Energy Delivering Thermocouple Assemblies and Associated Methods
US9138578B2 (en) 2013-09-10 2015-09-22 Medtronic Ardian Luxembourg S.A.R.L. Endovascular catheters with tuned control members and associated systems and methods
US9782211B2 (en) 2013-10-01 2017-10-10 Uptake Medical Technology Inc. Preferential volume reduction of diseased segments of a heterogeneous lobe
US10433902B2 (en) 2013-10-23 2019-10-08 Medtronic Ardian Luxembourg S.A.R.L. Current control methods and systems
US10149978B1 (en) 2013-11-07 2018-12-11 Nevro Corp. Spinal cord modulation for inhibiting pain via short pulse width waveforms, and associated systems and methods
CN105873630B (en) 2013-11-22 2020-01-03 隆佩瑟尔医疗公司 Device and method for assisted respiration by transvascular nerve stimulation
US10556107B2 (en) 2013-11-27 2020-02-11 Ebt Medical, Inc. Systems, methods and kits for peripheral nerve stimulation
US11633593B2 (en) 2013-11-27 2023-04-25 Ebt Medical, Inc. Treatment of pelvic floor disorders using targeted lower limb nerve stimulation
US20160263376A1 (en) * 2013-11-27 2016-09-15 The Governing Council Of The University Of Toronto Systems and methods for improved treatment of overactive bladder
US10646183B2 (en) 2014-01-10 2020-05-12 Tylerton International Inc. Detection of scar and fibrous cardiac zones
WO2015109401A1 (en) 2014-01-21 2015-07-30 Simon Fraser University Systems and related methods for optimization of multi-electrode nerve pacing
EP3099377B1 (en) 2014-01-27 2022-03-02 Medtronic Ireland Manufacturing Unlimited Company Neuromodulation catheters having jacketed neuromodulation elements and related devices
US9770583B2 (en) 2014-02-25 2017-09-26 Oculeve, Inc. Polymer formulations for nasolacrimal stimulation
US10492842B2 (en) 2014-03-07 2019-12-03 Medtronic Ardian Luxembourg S.A.R.L. Monitoring and controlling internally administered cryotherapy
US10463424B2 (en) 2014-03-11 2019-11-05 Medtronic Ardian Luxembourg S.A.R.L. Catheters with independent radial-expansion members and associated devices, systems, and methods
US9579149B2 (en) 2014-03-13 2017-02-28 Medtronic Ardian Luxembourg S.A.R.L. Low profile catheter assemblies and associated systems and methods
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
WO2015164280A1 (en) 2014-04-24 2015-10-29 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation catheters having braided shafts and associated systems and methods
US10610292B2 (en) 2014-04-25 2020-04-07 Medtronic Ardian Luxembourg S.A.R.L. Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology
US10709490B2 (en) 2014-05-07 2020-07-14 Medtronic Ardian Luxembourg S.A.R.L. Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods
US9959388B2 (en) 2014-07-24 2018-05-01 Boston Scientific Neuromodulation Corporation Systems, devices, and methods for providing electrical stimulation therapy feedback
EP3673952A1 (en) 2014-07-25 2020-07-01 Oculeve, Inc. Stimulation patterns for treating dry eye
US10272247B2 (en) 2014-07-30 2019-04-30 Boston Scientific Neuromodulation Corporation Systems and methods for stimulation-related volume analysis, creation, and sharing with integrated surgical planning and stimulation programming
WO2016016837A1 (en) 2014-07-30 2016-02-04 Navix International Limited Probe localization
US10265528B2 (en) 2014-07-30 2019-04-23 Boston Scientific Neuromodulation Corporation Systems and methods for electrical stimulation-related patient population volume analysis and use
WO2016033543A1 (en) 2014-08-28 2016-03-03 Medtronic Ardian Luxembourg S.A.R.L. Methods for assessing efficacy of renal neuromodulation and associated systems and devices
US10368775B2 (en) 2014-10-01 2019-08-06 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for evaluating neuromodulation therapy via hemodynamic responses
EP3204112A1 (en) 2014-10-07 2017-08-16 Boston Scientific Neuromodulation Corporation Systems, devices, and methods for electrical stimulation using feedback to adjust stimulation parameters
CA2965514A1 (en) 2014-10-22 2016-04-28 Oculeve, Inc. Contact lens for increasing tear production
US10207108B2 (en) 2014-10-22 2019-02-19 Oculeve, Inc. Implantable nasal stimulator systems and methods
CN107106843A (en) 2014-10-22 2017-08-29 奥库利维公司 Stimulating apparatus and method for treating xerophthalmia
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
EP3943032A1 (en) 2014-11-14 2022-01-26 Medtronic Ardian Luxembourg S.à.r.l. Catheter apparatuses for modulation of nerves in communication with the pulmonary system and associated systems
US10485604B2 (en) 2014-12-02 2019-11-26 Uptake Medical Technology Inc. Vapor treatment of lung nodules and tumors
WO2016090122A1 (en) * 2014-12-03 2016-06-09 PAVmed Inc. Systems and methods for percutaneous division of fibrous structures
US10667736B2 (en) 2014-12-17 2020-06-02 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing sympathetic nervous system tone for neuromodulation therapy
US10531906B2 (en) 2015-02-02 2020-01-14 Uptake Medical Technology Inc. Medical vapor generator
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10376308B2 (en) 2015-02-05 2019-08-13 Axon Therapies, Inc. Devices and methods for treatment of heart failure by splanchnic nerve ablation
JP7013023B2 (en) 2015-05-21 2022-01-31 イービーティー メディカル,インコーポレイテッド Systems and methods for the treatment of bladder dysfunction
US10780283B2 (en) 2015-05-26 2020-09-22 Boston Scientific Neuromodulation Corporation Systems and methods for analyzing electrical stimulation and selecting or manipulating volumes of activation
CN107530542B (en) 2015-05-26 2020-10-13 波士顿科学神经调制公司 System for analyzing electrical stimulation and selecting or manipulating activation volume
US10441800B2 (en) 2015-06-29 2019-10-15 Boston Scientific Neuromodulation Corporation Systems and methods for selecting stimulation parameters by targeting and steering
WO2017003946A1 (en) 2015-06-29 2017-01-05 Boston Scientific Neuromodulation Corporation Systems and methods for selecting stimulation parameters based on stimulation target region, effects, or side effects
US10603482B2 (en) * 2015-09-23 2020-03-31 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
US10071249B2 (en) 2015-10-09 2018-09-11 Boston Scientific Neuromodulation Corporation System and methods for clinical effects mapping for directional stimulation leads
US10207110B1 (en) 2015-10-13 2019-02-19 Axon Therapies, Inc. Devices and methods for treatment of heart failure via electrical modulation of a splanchnic nerve
US11318310B1 (en) 2015-10-26 2022-05-03 Nevro Corp. Neuromodulation for altering autonomic functions, and associated systems and methods
US10426958B2 (en) 2015-12-04 2019-10-01 Oculeve, Inc. Intranasal stimulation for enhanced release of ocular mucins and other tear proteins
WO2017112665A1 (en) * 2015-12-22 2017-06-29 Gupte Akshay Ashok Systems to provide sympathetic modulation therapy
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
CN114904142A (en) 2016-01-20 2022-08-16 赛博恩特医疗器械公司 Control of vagal nerve stimulation
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
EP3405255A4 (en) 2016-01-20 2019-10-16 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
JP6952699B2 (en) 2016-01-21 2021-10-20 カラ ヘルス, インコーポレイテッドCala Health, Inc. Systems, methods and devices for peripheral nerve regulation to treat diseases associated with overactive bladder
CN109310865B (en) 2016-01-25 2022-09-13 内弗洛公司 Electrostimulation treatment of congestive heart failure, and associated systems and methods
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10252048B2 (en) 2016-02-19 2019-04-09 Oculeve, Inc. Nasal stimulation for rhinitis, nasal congestion, and ocular allergies
US10786674B2 (en) 2016-03-08 2020-09-29 Medtronic, Inc. Medical therapy target definition
US10799701B2 (en) 2016-03-30 2020-10-13 Nevro Corp. Systems and methods for identifying and treating patients with high-frequency electrical signals
US10716942B2 (en) 2016-04-25 2020-07-21 Boston Scientific Neuromodulation Corporation System and methods for directional steering of electrical stimulation
US10736692B2 (en) 2016-04-28 2020-08-11 Medtronic Ardian Luxembourg S.A.R.L. Neuromodulation and associated systems and methods for the treatment of cancer
AU2017260237A1 (en) 2016-05-02 2018-11-22 Oculeve, Inc. Intranasal stimulation for treatment of meibomian gland disease and blepharitis
US11446504B1 (en) 2016-05-27 2022-09-20 Nevro Corp. High frequency electromagnetic stimulation for modulating cells, including spontaneously active and quiescent cells, and associated systems and methods
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
AU2017281934B2 (en) 2016-06-24 2019-11-14 Boston Scientific Neuromodulation Corporation Systems and methods for visual analytics of clinical effects
CA3031766A1 (en) 2016-07-29 2018-02-01 Howard Levin Devices, systems, and methods for treatment of heart failure by splanchnic nerve ablation
US10583286B2 (en) * 2016-08-23 2020-03-10 Boston Scientific Neuromodulation Corporation Methods and devices for neuromodulation of the adrenal gland
US10350404B2 (en) 2016-09-02 2019-07-16 Boston Scientific Neuromodulation Corporation Systems and methods for visualizing and directing stimulation of neural elements
US10780282B2 (en) 2016-09-20 2020-09-22 Boston Scientific Neuromodulation Corporation Systems and methods for steering electrical stimulation of patient tissue and determining stimulation parameters
JP6828149B2 (en) 2016-10-14 2021-02-10 ボストン サイエンティフィック ニューロモデュレイション コーポレイション Systems and methods for closed-loop determination of stimulation parameter settings for electrical stimulation systems
EP3532154B1 (en) 2016-10-28 2023-08-23 Medtronic, Inc. Autotitration of therapy using detected electrical activity
US10231784B2 (en) 2016-10-28 2019-03-19 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics
CN110022755A (en) 2016-12-02 2019-07-16 奥库利维公司 Device and method for xerophthalmia prediction and treatment recommendations
EP3558446B1 (en) * 2016-12-23 2022-08-03 NeuroMetrix, Inc. Smart electrode assembly for transcutaneous electrical nerve stimulation (tens)
WO2018128949A1 (en) 2017-01-03 2018-07-12 Boston Scientific Neuromodulation Corporation Systems and methods for selecting mri-compatible stimulation parameters
ES2821752T3 (en) 2017-01-10 2021-04-27 Boston Scient Neuromodulation Corp Systems and procedures for creating stimulation programs based on user-defined areas or volumes
US20180200513A1 (en) * 2017-01-18 2018-07-19 Boston Scientific Neuromodulation Corporation Modulation of the superior cervical ganglion for the treatment of insomnia
US10646713B2 (en) 2017-02-22 2020-05-12 Medtronic Ardian Luxembourg S.A.R.L. Systems, devices, and associated methods for treating patients via renal neuromodulation to reduce a risk of developing cognitive impairment
US10625082B2 (en) 2017-03-15 2020-04-21 Boston Scientific Neuromodulation Corporation Visualization of deep brain stimulation efficacy
WO2018187090A1 (en) 2017-04-03 2018-10-11 Boston Scientific Neuromodulation Corporation Systems and methods for estimating a volume of activation using a compressed database of threshold values
US11129673B2 (en) 2017-05-05 2021-09-28 Uptake Medical Technology Inc. Extra-airway vapor ablation for treating airway constriction in patients with asthma and COPD
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
WO2019006239A1 (en) 2017-06-30 2019-01-03 Lungpacer Medical Inc. Devices for prevention, moderation, and/or treatment of cognitive injury
US11160982B2 (en) 2017-07-05 2021-11-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating post-traumatic stress disorder in patients via renal neuromodulation
US11284934B2 (en) 2017-07-05 2022-03-29 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating sleep disorders in patients via renal neuromodulation
US10945788B2 (en) 2017-07-05 2021-03-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for treating depression in patients via renal neuromodulation
KR20190007595A (en) 2017-07-13 2019-01-23 주식회사 디플즈 Device for headache treatment through measuring brain wave and electrostimulation, and method using the same
WO2019014224A1 (en) 2017-07-14 2019-01-17 Boston Scientific Neuromodulation Corporation Systems and methods for estimating clinical effects of electrical stimulation
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
EP3668402A4 (en) 2017-08-14 2021-05-19 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
WO2019036180A1 (en) 2017-08-15 2019-02-21 Boston Scientific Neuromodulation Corporation Systems and methods for controlling electrical stimulation using multiple stimulation fields
US11344364B2 (en) 2017-09-07 2022-05-31 Uptake Medical Technology Inc. Screening method for a target nerve to ablate for the treatment of inflammatory lung disease
US11350988B2 (en) 2017-09-11 2022-06-07 Uptake Medical Technology Inc. Bronchoscopic multimodality lung tumor treatment
USD845467S1 (en) 2017-09-17 2019-04-09 Uptake Medical Technology Inc. Hand-piece for medical ablation catheter
US11419658B2 (en) 2017-11-06 2022-08-23 Uptake Medical Technology Inc. Method for treating emphysema with condensable thermal vapor
EP3709919A1 (en) 2017-11-17 2020-09-23 Medtronic Ardian Luxembourg S.à.r.l. Systems, devices, and associated methods for neuromodulation with enhanced nerve targeting
EP3723842A1 (en) 2017-12-11 2020-10-21 Galvani Bioelectronics Limited Neuromodulation of ganglia
US20210069511A1 (en) 2017-12-11 2021-03-11 Galvani Bioelectronics Limited Treatment and prevention of cardiac dysfunction
US11490946B2 (en) 2017-12-13 2022-11-08 Uptake Medical Technology Inc. Vapor ablation handpiece
WO2019118976A1 (en) 2017-12-17 2019-06-20 Axon Therapies, Inc. Methods and devices for endovascular ablation of a splanchnic nerve
CN111787976A (en) * 2017-12-20 2020-10-16 加尔瓦尼生物电子有限公司 Treatment of acute medical conditions
US11857778B2 (en) 2018-01-17 2024-01-02 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11253189B2 (en) 2018-01-24 2022-02-22 Medtronic Ardian Luxembourg S.A.R.L. Systems, devices, and methods for evaluating neuromodulation therapy via detection of magnetic fields
US11478298B2 (en) 2018-01-24 2022-10-25 Medtronic Ardian Luxembourg S.A.R.L. Controlled irrigation for neuromodulation systems and associated methods
US11116561B2 (en) 2018-01-24 2021-09-14 Medtronic Ardian Luxembourg S.A.R.L. Devices, agents, and associated methods for selective modulation of renal nerves
US10959669B2 (en) 2018-01-24 2021-03-30 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing the efficacy of neuromodulation therapy
JP7334167B2 (en) 2018-01-26 2023-08-28 アクソン セラピーズ,インク. Method and device for endovascular ablation of visceral nerves
CA3096702A1 (en) * 2018-04-12 2019-10-17 Reshape Lifesciences, Inc. Simultaneous multi-site vagus nerve neuromodulation for improved glycemic control system and methods
MX2020011008A (en) 2018-04-19 2021-01-20 Iota Biosciences Inc Implants using ultrasonic communication for modulating splenic nerve activity.
WO2019204773A1 (en) 2018-04-19 2019-10-24 Iota Biosciences, Inc. Implants using ultrasonic communication for neural sensing and stimulation
US11660443B2 (en) 2018-04-20 2023-05-30 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via electrical trigeminal nerve stimulation
US11285329B2 (en) 2018-04-27 2022-03-29 Boston Scientific Neuromodulation Corporation Systems and methods for visualizing and programming electrical stimulation
WO2019210202A1 (en) 2018-04-27 2019-10-31 Boston Scientific Neuromodulation Corporation Multi-mode electrical stimulation systems and methods of making and using
US11351381B2 (en) 2018-05-18 2022-06-07 Washington University Systems and methods for stimulating sympathetic nervous system
US11633120B2 (en) 2018-09-04 2023-04-25 Medtronic Ardian Luxembourg S.A.R.L. Systems and methods for assessing efficacy of renal neuromodulation therapy
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
EP3877043A4 (en) 2018-11-08 2022-08-24 Lungpacer Medical Inc. Stimulation systems and related user interfaces
AU2020207940A1 (en) 2019-01-17 2021-08-12 Nevro Corp. Sensory threshold and/or adaptation for neurological therapy screening and/or parameter selection, and associated systems and methods
US11590352B2 (en) 2019-01-29 2023-02-28 Nevro Corp. Ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods
US11653927B2 (en) 2019-02-18 2023-05-23 Uptake Medical Technology Inc. Vapor ablation treatment of obstructive lung disease
JP2022532375A (en) 2019-05-16 2022-07-14 ラングペーサー メディカル インコーポレイテッド Systems and methods for detection and stimulation
EP3983057A4 (en) 2019-06-12 2023-07-12 Lungpacer Medical Inc. Circuitry for medical stimulation systems
EP3917426B1 (en) 2019-06-20 2023-09-06 Axon Therapies, Inc. Devices for endovascular ablation of a splanchnic nerve
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
ES2960299T3 (en) 2020-01-17 2024-03-04 Axon Therapies Inc Devices for endovascular ablation of a splanchnic nerve
US11938324B2 (en) 2020-05-21 2024-03-26 The Feinstein Institutes For Medical Research Systems and methods for vagus nerve stimulation
WO2023250426A1 (en) * 2022-06-22 2023-12-28 Reshape Lifesciences, Inc. Neuromodulation of two or more neuronal targets in treatment of a medical condition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700282A (en) * 1995-10-13 1997-12-23 Zabara; Jacob Heart rhythm stabilization using a neurocybernetic prosthesis
US6073048A (en) * 1995-11-17 2000-06-06 Medtronic, Inc. Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3662758A (en) * 1969-06-30 1972-05-16 Mentor Corp Stimulator apparatus for muscular organs with external transmitter and implantable receiver
US4585005A (en) * 1984-04-06 1986-04-29 Regents Of University Of California Method and pacemaker for stimulating penile erection
US4830008A (en) * 1987-04-24 1989-05-16 Meer Jeffrey A Method and system for treatment of sleep apnea
US4881526A (en) * 1988-05-27 1989-11-21 Empi, Inc. Intravaginal electrode and stimulation system for controlling female urinary incontinence
US4917092A (en) * 1988-07-13 1990-04-17 Medical Designs, Inc. Transcutaneous nerve stimulator for treatment of sympathetic nerve dysfunction
US5199428A (en) * 1991-03-22 1993-04-06 Medtronic, Inc. Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload
DK80593D0 (en) * 1993-07-06 1993-07-06 Scanvaegt As PROCEDURES AND PLACES FOR WEIGHTING OBJECTIVES
EP0688579B1 (en) 1994-06-24 2001-08-22 St. Jude Medical AB Device for heart therapy
EP0688578B1 (en) 1994-06-24 1999-11-10 Pacesetter AB Arrhythmia detector
US5833595A (en) * 1994-09-06 1998-11-10 Lin; Vernon Wen-Hau Treatment of excretory problems
US5527351A (en) * 1994-09-21 1996-06-18 Friedman; Mark H. Treatment of vascular and tension headache atypical facial pain allergic rhinitis and cervical muscle hyperactivity
US5591216A (en) * 1995-05-19 1997-01-07 Medtronic, Inc. Method for treatment of sleep apnea by electrical stimulation
RU2108817C1 (en) 1995-05-22 1998-04-20 Карашуров Сергей Егорович Method for treating the cases of bronchial asthma
US5700828A (en) * 1995-12-07 1997-12-23 Life Resuscitation Technologies, Inc. Treatment or prevention of anoxic or ischemic brain injury with melatonin-containing compositions
GB9621243D0 (en) * 1996-10-11 1996-11-27 Nokia Mobile Phones Ltd Dect/gcm interworking
US6058331A (en) 1998-04-27 2000-05-02 Medtronic, Inc. Apparatus and method for treating peripheral vascular disease and organ ischemia by electrical stimulation with closed loop feedback control
US7599736B2 (en) 2001-07-23 2009-10-06 Dilorenzo Biomedical, Llc Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
US6230052B1 (en) * 1999-01-29 2001-05-08 Andy Wolff Device and method for stimulating salivation
FI106493B (en) * 1999-02-09 2001-02-15 Nokia Mobile Phones Ltd A method and system for reliably transmitting packet data
US6272377B1 (en) 1999-10-01 2001-08-07 Cardiac Pacemakers, Inc. Cardiac rhythm management system with arrhythmia prediction and prevention
DE50014442D1 (en) 1999-11-30 2007-08-09 Biotronik Gmbh & Co Kg Device for controlling heart rate and cardiac pumping force
US6356787B1 (en) 2000-02-24 2002-03-12 Electro Core Techniques, Llc Method of treating facial blushing by electrical stimulation of the sympathetic nerve chain
US6356786B1 (en) 2000-01-20 2002-03-12 Electrocore Techniques, Llc Method of treating palmar hyperhydrosis by electrical stimulation of the sympathetic nervous chain
US6438423B1 (en) * 2000-01-20 2002-08-20 Electrocore Technique, Llc Method of treating complex regional pain syndromes by electrical stimulation of the sympathetic nerve chain
US6612983B1 (en) * 2000-03-28 2003-09-02 Medtronic, Inc. Pancreatic secretion response to stimulation test protocol
WO2002034330A2 (en) 2000-10-26 2002-05-02 Medtronic, Inc. Method and apparatus to minimize the effects of a cardiac insult
US6832114B1 (en) 2000-11-21 2004-12-14 Advanced Bionics Corporation Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes
US6633779B1 (en) * 2000-11-27 2003-10-14 Science Medicus, Inc. Treatment of asthma and respiratory disease by means of electrical neuro-receptive waveforms
JP2002330934A (en) 2001-05-08 2002-11-19 Tanita Corp Autonomic nerve activity measuring instrument
US6928320B2 (en) * 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US6721603B2 (en) 2002-01-25 2004-04-13 Cyberonics, Inc. Nerve stimulation as a treatment for pain
US7689276B2 (en) 2002-09-13 2010-03-30 Leptos Biomedical, Inc. Dynamic nerve stimulation for treatment of disorders
US7236822B2 (en) 2002-03-22 2007-06-26 Leptos Biomedical, Inc. Wireless electric modulation of sympathetic nervous system
US7239912B2 (en) 2002-03-22 2007-07-03 Leptos Biomedical, Inc. Electric modulation of sympathetic nervous system
US7149574B2 (en) 2003-06-09 2006-12-12 Palo Alto Investors Treatment of conditions through electrical modulation of the autonomic nervous system
US20050075702A1 (en) 2003-10-01 2005-04-07 Medtronic, Inc. Device and method for inhibiting release of pro-inflammatory mediator

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5700282A (en) * 1995-10-13 1997-12-23 Zabara; Jacob Heart rhythm stabilization using a neurocybernetic prosthesis
US6073048A (en) * 1995-11-17 2000-06-06 Medtronic, Inc. Baroreflex modulation with carotid sinus nerve stimulation for the treatment of heart failure

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8915741B2 (en) 2003-08-18 2014-12-23 Cardiac Pacemakers, Inc. Sleep quality data collection and evaluation

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