WO2003036263A3 - Method and apparatus for parallel dispensing of defined volumes of solid particles - Google Patents
Method and apparatus for parallel dispensing of defined volumes of solid particles Download PDFInfo
- Publication number
- WO2003036263A3 WO2003036263A3 PCT/US2002/034447 US0234447W WO03036263A3 WO 2003036263 A3 WO2003036263 A3 WO 2003036263A3 US 0234447 W US0234447 W US 0234447W WO 03036263 A3 WO03036263 A3 WO 03036263A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tubes
- particle material
- particle
- solid particles
- lowered
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0244—Drop counters; Drop formers using pins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/56—Means for indicating position of a recipient or sample in an array
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
- B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00466—Beads in a slurry
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/021—Adjust spacings in an array of wells, pipettes or holders, format transfer between arrays of different size or geometry
- B01L2200/022—Variable spacings
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0657—Pipetting powder
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/02—Water baths; Sand baths; Air baths
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00168—Manufacturing or preparing test elements
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00207—Handling bulk quantities of analyte
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00326—Analysers with modular structure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00564—Handling or washing solid phase elements, e.g. beads
- G01N2035/00574—Means for distributing beads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002464467A CA2464467A1 (en) | 2001-10-26 | 2002-10-25 | Method and apparatus for parallel dispensing of defined volumes of solid particles |
EP02784312A EP1451674A4 (en) | 2001-10-26 | 2002-10-25 | Method and apparatus for parallel dispensing of defined volumes of solid particles |
JP2003538713A JP2005507078A (en) | 2001-10-26 | 2002-10-25 | Method and apparatus for parallel distribution of a defined volume of solid particles |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34810701P | 2001-10-26 | 2001-10-26 | |
US34874501P | 2001-10-26 | 2001-10-26 | |
US60/348,107 | 2001-10-26 | ||
US60/348,745 | 2001-10-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003036263A2 WO2003036263A2 (en) | 2003-05-01 |
WO2003036263A3 true WO2003036263A3 (en) | 2003-10-30 |
Family
ID=26995568
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/034447 WO2003036263A2 (en) | 2001-10-26 | 2002-10-25 | Method and apparatus for parallel dispensing of defined volumes of solid particles |
PCT/US2002/034490 WO2003035239A2 (en) | 2001-10-26 | 2002-10-25 | Resin dispensing device |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/034490 WO2003035239A2 (en) | 2001-10-26 | 2002-10-25 | Resin dispensing device |
Country Status (6)
Country | Link |
---|---|
US (3) | US7159740B2 (en) |
EP (2) | EP1451674A4 (en) |
JP (2) | JP2005507078A (en) |
AU (1) | AU2002348099A1 (en) |
CA (2) | CA2464467A1 (en) |
WO (2) | WO2003036263A2 (en) |
Cited By (3)
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---|---|---|---|---|
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US9244069B2 (en) | 2009-07-29 | 2016-01-26 | Dynex Technologies | Sample plate systems and methods |
US9523701B2 (en) | 2009-07-29 | 2016-12-20 | Dynex Technologies, Inc. | Sample plate systems and methods |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
US7285422B1 (en) * | 1997-01-23 | 2007-10-23 | Sequenom, Inc. | Systems and methods for preparing and analyzing low volume analyte array elements |
US6630006B2 (en) * | 1999-06-18 | 2003-10-07 | The Regents Of The University Of California | Method for screening microcrystallizations for crystal formation |
DE60030310T2 (en) * | 1999-10-20 | 2007-08-23 | Gentra Systems Inc., Minneapolis | MIXING AND CASTING APPARATUS WITH ROTATABLE ARM AND ASSOCIATED VESSEL |
US20020151040A1 (en) | 2000-02-18 | 2002-10-17 | Matthew O' Keefe | Apparatus and methods for parallel processing of microvolume liquid reactions |
KR100649342B1 (en) | 2000-10-30 | 2006-11-27 | 시쿼넘, 인코포레이티드 | Method and apparatus for delivery of submicroliter volumes onto a substrate |
FR2820058B1 (en) * | 2001-01-29 | 2004-01-30 | Commissariat Energie Atomique | METHOD AND SYSTEM FOR MAKING A CONTINUOUS FLOW REALIZATION OF A BIOLOGICAL, CHEMICAL OR BIOCHEMICAL PROTOCOL |
CN1385518A (en) * | 2001-04-23 | 2002-12-18 | 株式会社百尼尔 | Microarrayer for microarrangement for biological test material and microarray pin used in same |
JP2005507078A (en) * | 2001-10-26 | 2005-03-10 | セクエノム, インコーポレイテッド | Method and apparatus for parallel distribution of a defined volume of solid particles |
US7813559B2 (en) * | 2001-11-13 | 2010-10-12 | Cyberoptics Corporation | Image analysis for pick and place machines with in situ component placement inspection |
US7239399B2 (en) * | 2001-11-13 | 2007-07-03 | Cyberoptics Corporation | Pick and place machine with component placement inspection |
DE10160041A1 (en) * | 2001-12-06 | 2003-09-25 | Marconi Comm Gmbh | Electronic circuit module and method for its assembly |
EP1323465A1 (en) * | 2001-12-31 | 2003-07-02 | Corning Incorporated | Flexible high density array print head with systems and methods for aligning pin plate, reservoir and substrate with respect to each other |
US6827905B2 (en) * | 2002-01-14 | 2004-12-07 | Becton, Dickinson And Company | Pin tool apparatus and method |
US7410615B2 (en) * | 2002-01-24 | 2008-08-12 | Perkinelmer Las, Inc. | Precision liquid dispensing system |
CA2484676A1 (en) * | 2002-05-03 | 2003-11-13 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof, and related methods |
US7452712B2 (en) | 2002-07-30 | 2008-11-18 | Applied Biosystems Inc. | Sample block apparatus and method of maintaining a microcard on a sample block |
US7144554B1 (en) * | 2002-08-02 | 2006-12-05 | Hamilton Company | Ultra low volume probe |
AU2003268110A1 (en) * | 2002-08-16 | 2004-03-03 | Miragene, Inc. | Integrated system for printing, processing, and imaging protein microarrays |
JP2006505803A (en) * | 2002-11-04 | 2006-02-16 | トランスフォーム・ファーマシューティカルズ・インコーポレイテッド | How to handle a small amount of solid |
CA2503797A1 (en) * | 2002-11-08 | 2004-05-27 | Irm, Llc | Systems and methods of sorting samples |
US7208124B2 (en) * | 2002-11-19 | 2007-04-24 | Genetix Limited | Microarraying process and apparatus |
US20060094108A1 (en) * | 2002-12-20 | 2006-05-04 | Karl Yoder | Thermal cycler for microfluidic array assays |
WO2004074818A2 (en) * | 2002-12-20 | 2004-09-02 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
US20030166263A1 (en) * | 2002-12-30 | 2003-09-04 | Haushalter Robert C. | Microfabricated spotting apparatus for producing low cost microarrays |
AU2003900780A0 (en) * | 2003-02-21 | 2003-03-13 | Vision Biosystems Limited | Analysis system and procedure |
US7204960B2 (en) * | 2003-03-03 | 2007-04-17 | Asm Assembly Automation Ltd. | Apparatus and method for calibration of a dispensing system |
US6970240B2 (en) * | 2003-03-10 | 2005-11-29 | Applera Corporation | Combination reader |
US20050112783A1 (en) * | 2003-08-04 | 2005-05-26 | Irm, Llc | Non-pressure based fluid transfer in assay detection systems and related methods |
US20050226779A1 (en) * | 2003-09-19 | 2005-10-13 | Oldham Mark F | Vacuum assist for a microplate |
US20050221358A1 (en) * | 2003-09-19 | 2005-10-06 | Carrillo Albert L | Pressure chamber clamp mechanism |
US20070015289A1 (en) * | 2003-09-19 | 2007-01-18 | Kao H P | Dispenser array spotting |
US20050226771A1 (en) * | 2003-09-19 | 2005-10-13 | Lehto Dennis A | High speed microplate transfer |
US20050233472A1 (en) * | 2003-09-19 | 2005-10-20 | Kao H P | Spotting high density plate using a banded format |
WO2005028109A2 (en) * | 2003-09-19 | 2005-03-31 | Applera Corporation | Microplates useful for conducting thermocycled nucleotide amplification |
EP2322278B1 (en) * | 2003-10-24 | 2017-01-04 | Aushon Biosystems, Inc. | Apparatus and Method for Dispensing Fluid, Semi-Solid and Solid Samples |
US7706595B2 (en) | 2003-11-07 | 2010-04-27 | Cyberoptics Corporation | Pick and place machine with workpiece motion inspection |
US7416710B1 (en) | 2003-12-31 | 2008-08-26 | Takeda San Diego, Inc. | Method and system for performing crystallization trials |
AU2005222618A1 (en) | 2004-03-12 | 2005-09-29 | Biotrove, Inc. | Nanoliter array loading |
US7077175B2 (en) | 2004-04-09 | 2006-07-18 | Hongfeng Yin | Particle packing of microdevice |
US7455814B2 (en) * | 2004-04-23 | 2008-11-25 | Giblin Leonard J | Metered dispenser and aspirator device |
US20070221684A1 (en) * | 2004-05-10 | 2007-09-27 | Bernd Steinbrenner | Device for Receiving and Dispensing Liquids |
CN101014500A (en) * | 2004-07-30 | 2007-08-08 | 诺瓦提斯公司 | Anti-bacterial syringe and associated reservoir |
CA2575350A1 (en) * | 2004-08-04 | 2006-04-06 | Biotrove, Inc. | Method and system for registering dispenser array location |
US20060105453A1 (en) | 2004-09-09 | 2006-05-18 | Brenan Colin J | Coating process for microfluidic sample arrays |
US20060075631A1 (en) * | 2004-10-05 | 2006-04-13 | Case Steven K | Pick and place machine with improved component pick up inspection |
US20080279727A1 (en) * | 2005-03-01 | 2008-11-13 | Haushalter Robert C | Polymeric Fluid Transfer and Printing Devices |
US7622079B2 (en) * | 2005-03-22 | 2009-11-24 | Applied Biosystems, Llc | Dual nest microplate spotter |
US20070003126A1 (en) * | 2005-05-19 | 2007-01-04 | Case Steven K | Method and apparatus for evaluating a component pick action in an electronics assembly machine |
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DE102005049920A1 (en) * | 2005-10-17 | 2007-04-19 | Manz Automation Ag | robotic assembly |
DE112006003019T5 (en) * | 2005-10-31 | 2008-10-23 | Cyberoptics Corp., Golden Valley | Electronics mounting device with built-in solder paste test |
US8150548B2 (en) * | 2005-11-07 | 2012-04-03 | Sasan Raghibizadeh | Apparatus for process automation using pin array and actuators |
US20080026483A1 (en) * | 2006-06-14 | 2008-01-31 | Oldenburg Kevin R | Thermal-cycling devices and methods of using the same |
US20080101996A1 (en) * | 2006-10-31 | 2008-05-01 | Taigen Bioscience Corporation | Multi-channel design for a liquid-handling pipette |
WO2008089449A2 (en) * | 2007-01-19 | 2008-07-24 | Biodot, Inc. | Systems and methods for high speed array printing and hybridization |
US20080182340A1 (en) * | 2007-01-26 | 2008-07-31 | Lemmo Anthony V | Non-contact positive dispense solid powder sampling apparatus and method |
JP2008241512A (en) * | 2007-03-28 | 2008-10-09 | Matsushita Electric Ind Co Ltd | System for processing workpiece |
WO2009039122A2 (en) | 2007-09-17 | 2009-03-26 | Sequenom, Inc. | Integrated robotic sample transfer device |
WO2009061416A2 (en) * | 2007-11-05 | 2009-05-14 | Velocys Inc. | Loading or unloading of particulates or out of microchannel reactors. |
US8377390B1 (en) * | 2008-05-29 | 2013-02-19 | Stc.Unm | Anisotropic wetting behavior on one-dimensional patterned surfaces for applications to microfluidic devices |
US20100011889A1 (en) * | 2008-07-16 | 2010-01-21 | Biodot, Inc. | Handheld powder handling devices and related methods |
US8534447B2 (en) * | 2008-09-16 | 2013-09-17 | Ibis Biosciences, Inc. | Microplate handling systems and related computer program products and methods |
US8180487B1 (en) | 2008-09-30 | 2012-05-15 | Western Digital Technologies, Inc. | Calibrated vision based robotic system |
US8135208B1 (en) * | 2009-01-15 | 2012-03-13 | Western Digital Technologies, Inc. | Calibrated vision based robotic system utilizing upward and downward looking cameras |
EP2263802A1 (en) * | 2009-05-25 | 2010-12-22 | F. Hoffmann-La Roche AG | System and method for dispensing fluids |
US8858899B2 (en) * | 2009-06-10 | 2014-10-14 | Ge Healthcare Bio-Sciences Ab | Fraction collector |
CA2779758C (en) | 2009-11-03 | 2019-09-24 | 7685297 Canada Inc. | Systems and methods for preparing samples for chemical analysis |
US8527090B2 (en) * | 2010-03-30 | 2013-09-03 | Mckesson Automation Inc. | Method, computer program product and apparatus for facilitating storage and/or retrieval of unit dose medications |
DE102010018298B4 (en) * | 2010-04-23 | 2013-05-29 | Grohmann Engineering Gmbh | retaining strip |
EP2577320B1 (en) | 2010-06-04 | 2019-04-17 | Parker-Hannificn Corporation | Miniaturized syringe pump system and modules |
JP5592710B2 (en) * | 2010-06-17 | 2014-09-17 | セイコーインスツル株式会社 | Pitch converter |
GB201012490D0 (en) * | 2010-07-26 | 2010-09-08 | Randox Lab Ltd | Sealed well assembly, cartridge thereof, and apparatus and method for opening a sealed well assembly |
US9387476B2 (en) * | 2010-10-27 | 2016-07-12 | Illumina, Inc. | Flow cells for biological or chemical analysis |
JP5417351B2 (en) * | 2011-01-26 | 2014-02-12 | 株式会社日立ハイテクノロジーズ | Sample transport system and control method thereof |
DE202011000837U1 (en) * | 2011-04-08 | 2011-06-09 | CyBio AG, 07745 | pipetting |
DK2734848T3 (en) * | 2011-07-21 | 2021-09-06 | Brooks Automation Inc | Method and device for compensating for size variations in low temperature sample group holders |
JP6021909B2 (en) * | 2011-07-21 | 2016-11-09 | ブルックス オートメーション インコーポレイテッド | Method and apparatus for correction of dimensional changes in low temperature sample group holders |
EP2771128A4 (en) * | 2011-10-28 | 2015-09-30 | Hewlett Packard Development Co | Parallel addressing method |
CN104105970A (en) | 2012-02-16 | 2014-10-15 | 株式会社日立高新技术 | System for adjusting automatic analysis device, method for adjusting automatic analysis device |
JP6233889B2 (en) * | 2012-06-18 | 2017-11-22 | 国立研究開発法人理化学研究所 | Sample dispensing apparatus and protein crystallization method |
US9555407B2 (en) | 2013-03-14 | 2017-01-31 | Protedyne Corporation | Laser triangulation for pipette tip position |
US9844782B2 (en) | 2013-06-21 | 2017-12-19 | Coldblock Technologies Inc. | Systems and methods for preparing samples for chemical analysis using a cooled digestion zone |
US10082417B2 (en) * | 2013-12-30 | 2018-09-25 | Nordson Corporation | Calibration methods for a viscous fluid dispensing system |
CN103760077B (en) * | 2014-01-16 | 2016-05-25 | 华测检测认证集团股份有限公司 | Atmosphere particle monitoring system |
AU2015279191B2 (en) * | 2014-06-27 | 2018-07-26 | F. Hoffmann-La Roche Ag | Automated specimen processing systems and methods of detecting specimen-bearing microscope slides |
US10379130B2 (en) | 2015-06-26 | 2019-08-13 | Abbott Laboratories | Reaction vessel exchanger device for a diagnostic analyzer |
CN109564237B (en) | 2016-06-30 | 2022-12-13 | 拜克门寇尔特公司 | Substance distribution evaluation system |
WO2018091938A1 (en) * | 2016-11-18 | 2018-05-24 | Sm Research Inc. | Biologic sample preparation system and related method |
GB2566111B (en) * | 2017-09-05 | 2022-07-13 | Arrayjet Ltd | Method and device for producing a printed microarray and verifying the same |
EP3644064B1 (en) * | 2018-10-23 | 2021-08-18 | Roche Diagnostics GmbH | Method of handling laboratory sample containers and apparatus for handling laboratory sample containers |
US11465900B2 (en) | 2019-04-12 | 2022-10-11 | Fluid Management, Inc. | Methods and systems for colorant dispenser alignment |
CN110658166B (en) * | 2019-09-30 | 2022-03-25 | 重庆科技学院 | Micro-fluidic chip and system thereof, and detection method of heavy metal ions in water body |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5798035A (en) * | 1996-10-03 | 1998-08-25 | Pharmacopeia, Inc. | High throughput solid phase chemical synthesis utilizing thin cylindrical reaction vessels useable for biological assay |
US5865224A (en) * | 1996-12-20 | 1999-02-02 | Life Technologies, Inc. | Method and apparatus for automated dispensing |
US6416718B1 (en) * | 1998-05-29 | 2002-07-09 | Ontogen Corporation | Sample wash station assembly |
US6432365B1 (en) * | 2000-04-14 | 2002-08-13 | Discovery Partners International, Inc. | System and method for dispensing solution to a multi-well container |
Family Cites Families (115)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9394A (en) * | 1852-11-09 | Brick-machnsfe | ||
US150903A (en) * | 1874-05-12 | Improvement in feathering paddle-wheels | ||
US142483A (en) * | 1873-09-02 | Improvement in supplementary ovens for cooking-stoves | ||
US176803A (en) * | 1876-05-02 | Improvement in horse-detachers | ||
US187488A (en) * | 1877-02-20 | Improvement in stove-grates | ||
US21734A (en) * | 1858-10-12 | Tholomew | ||
US109085A (en) * | 1870-11-08 | Improvement in paper-files | ||
US8615A (en) * | 1851-12-23 | sloan | ||
US42112A (en) * | 1864-03-29 | Improvement in grain-drills | ||
US42046A (en) * | 1864-03-22 | Improvement in baling-presses | ||
US12902A (en) * | 1855-05-22 | Improvement in sewing-magh ines | ||
US15666A (en) * | 1856-09-02 | Buckle for wearing-apparel | ||
US36057A (en) * | 1862-07-29 | Improvement in rattan machinery | ||
US5478A (en) * | 1848-03-21 | Cooking-stove | ||
US26732A (en) * | 1860-01-03 | dreysel | ||
US104389A (en) * | 1870-06-14 | Improvement in oil-cabinets | ||
US3465A (en) * | 1844-03-09 | Improvement in wheel-plows | ||
US40130A (en) * | 1863-09-29 | Improvement in grain-driers | ||
US137046A (en) * | 1873-03-25 | Improvement in washing-machines | ||
US4196053A (en) * | 1977-10-04 | 1980-04-01 | Hartung, Kuhn & Co. Maschinenfabrik Gmbh | Equipment for operating coke oven service machines |
US4101284A (en) * | 1977-10-25 | 1978-07-18 | Abbott Laboratories | Multiple bead dispenser for diagnostic assay |
US4198275A (en) * | 1977-10-27 | 1980-04-15 | Hartung, Kuhn & Co. Maschinenfabrik Gmbh | Equipment for extracting and purifying dirty gases arising on the coke side of a battery of chamber coke ovens with vertical flues |
DE2837319C2 (en) * | 1978-08-26 | 1983-04-21 | Battelle-Institut E.V., 6000 Frankfurt | Pipette system for the exact volume removal and line-like deposition of a material in suspension |
US4498510A (en) * | 1982-08-20 | 1985-02-12 | Minshew Jr Edward C | Device for drawing, holding and dispensing liquid |
US4554839A (en) * | 1983-10-14 | 1985-11-26 | Cetus Corporation | Multiple trough vessel for automated liquid handling apparatus |
US5038852A (en) | 1986-02-25 | 1991-08-13 | Cetus Corporation | Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
CH671526A5 (en) * | 1985-12-17 | 1989-09-15 | Hamilton Bonaduz Ag | |
US5104621A (en) * | 1986-03-26 | 1992-04-14 | Beckman Instruments, Inc. | Automated multi-purpose analytical chemistry processing center and laboratory work station |
US4865986A (en) * | 1988-10-06 | 1989-09-12 | Coy Corporation | Temperature control apparatus |
US5187084A (en) * | 1990-06-22 | 1993-02-16 | The Dow Chemical Company | Automatic air temperature cycler and method of use in polymerose chain reaction |
US5435378A (en) * | 1991-06-04 | 1995-07-25 | Process And Equipment Development, Inc. | Apparatus for accurately heating and cooling articles |
US5958202A (en) * | 1992-09-14 | 1999-09-28 | Perseptive Biosystems, Inc. | Capillary electrophoresis enzyme immunoassay |
US5601141A (en) * | 1992-10-13 | 1997-02-11 | Intelligent Automation Systems, Inc. | High throughput thermal cycler |
US6436635B1 (en) | 1992-11-06 | 2002-08-20 | Boston University | Solid phase sequencing of double-stranded nucleic acids |
US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
US6194144B1 (en) | 1993-01-07 | 2001-02-27 | Sequenom, Inc. | DNA sequencing by mass spectrometry |
EP1262564A3 (en) | 1993-01-07 | 2004-03-31 | Sequenom, Inc. | Dna sequencing by mass spectrometry |
AU687801B2 (en) | 1993-03-19 | 1998-03-05 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
US6074823A (en) * | 1993-03-19 | 2000-06-13 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
CA2130013C (en) | 1993-09-10 | 1999-03-30 | Rolf Moser | Apparatus for automatic performance of temperature cycles |
FR2714465B1 (en) * | 1993-12-28 | 1996-03-15 | D Autry Eric Marteau | Powder collection and distribution device. |
DE4423878A1 (en) * | 1994-07-07 | 1996-01-11 | Boehringer Mannheim Gmbh | Device and method for separating magnetic microparticles |
US6428955B1 (en) | 1995-03-17 | 2002-08-06 | Sequenom, Inc. | DNA diagnostics based on mass spectrometry |
CA2183638C (en) * | 1995-03-20 | 2001-03-20 | Tajima Hideji | Liquid processing method making use of pipette device and apparatus for same |
FI951766A0 (en) * | 1995-04-12 | 1995-04-12 | Labsystems Oy | Faspipett |
US6146854A (en) | 1995-08-31 | 2000-11-14 | Sequenom, Inc. | Filtration processes, kits and devices for isolating plasmids |
DE69634696T2 (en) * | 1995-10-06 | 2006-01-19 | PerSeptive Biosystems, Inc., Framingham | METHOD AND TEST SYSTEM FOR HYBRIDIZATION ANALYSIS USING PEPTIDE NUCLEIC ACID PROBLEMS |
US5722470A (en) * | 1995-11-09 | 1998-03-03 | Glaxo Group Limited | Bead dispensing device and methods |
AU2069597A (en) * | 1996-03-04 | 1997-09-22 | Genetrace Systems, Inc. | Methods of screening nucleic acids using mass spectrometry |
AU2217597A (en) | 1996-03-18 | 1997-10-22 | Sequenom, Inc. | Dna sequencing by mass spectrometry |
US6074609A (en) * | 1996-04-24 | 2000-06-13 | Glaxo Wellcome Inc. | Systems for arraying beads |
US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
US6022688A (en) | 1996-05-13 | 2000-02-08 | Sequenom, Inc. | Method for dissociating biotin complexes |
CA2255658C (en) * | 1996-05-20 | 2007-07-17 | Precision System Science Co., Ltd. | Method and apparatus for controlling magnetic particles by pipetting machine |
IL127560A0 (en) * | 1996-06-14 | 1999-10-28 | Sarnoff Corp | Method for polynucleotide sequencing |
DE19629143A1 (en) * | 1996-07-19 | 1998-01-22 | Bayer Ag | Device for separating micro objects |
US5777324A (en) * | 1996-09-19 | 1998-07-07 | Sequenom, Inc. | Method and apparatus for maldi analysis |
US5965363A (en) * | 1996-09-19 | 1999-10-12 | Genetrace Systems Inc. | Methods of preparing nucleic acids for mass spectrometric analysis |
US5854684A (en) * | 1996-09-26 | 1998-12-29 | Sarnoff Corporation | Massively parallel detection |
US5872623A (en) * | 1996-09-26 | 1999-02-16 | Sarnoff Corporation | Massively parallel detection |
US5885430A (en) * | 1996-10-04 | 1999-03-23 | Spectrumedix Corporation | Capillary tube holder for an electrophoretic apparatus |
US6133436A (en) | 1996-11-06 | 2000-10-17 | Sequenom, Inc. | Beads bound to a solid support and to nucleic acids |
US6140053A (en) | 1996-11-06 | 2000-10-31 | Sequenom, Inc. | DNA sequencing by mass spectrometry via exonuclease degradation |
DE19782097T1 (en) | 1996-11-06 | 1999-10-14 | Sequenom Inc | Compositions and methods for immobilizing nucleic acids on solid supports |
US5900481A (en) * | 1996-11-06 | 1999-05-04 | Sequenom, Inc. | Bead linkers for immobilizing nucleic acids to solid supports |
CA2268740C (en) | 1996-11-06 | 2010-07-20 | Sequenom, Inc. | High density immobilization of nucleic acids |
US6024925A (en) * | 1997-01-23 | 2000-02-15 | Sequenom, Inc. | Systems and methods for preparing low volume analyte array elements |
CA2270132A1 (en) | 1996-11-06 | 1998-05-14 | Sequenom, Inc. | Dna diagnostics based on mass spectrometry |
CA2278146A1 (en) * | 1997-01-17 | 1998-07-23 | John Gerald Gleason | Apparatus and process for arraying beads |
US6047854A (en) * | 1997-02-26 | 2000-04-11 | Sarnoff Corporation | Bead dispersement devices |
US5961800A (en) * | 1997-05-08 | 1999-10-05 | Sarnoff Corporation | Indirect electrode-based pumps |
US6451260B1 (en) | 1997-08-26 | 2002-09-17 | Dyax Corp. | Method for producing microporous elements, the microporous elements thus produced and uses thereof |
US6207370B1 (en) * | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
US6207031B1 (en) * | 1997-09-15 | 2001-03-27 | Whitehead Institute For Biomedical Research | Methods and apparatus for processing a sample of biomolecular analyte using a microfabricated device |
US5964381A (en) * | 1997-11-12 | 1999-10-12 | Ljl Biosystems, Inc. | Device for projectile dispensing of small volume liquid samples |
US5992820A (en) * | 1997-11-19 | 1999-11-30 | Sarnoff Corporation | Flow control in microfluidics devices by controlled bubble formation |
US6268131B1 (en) | 1997-12-15 | 2001-07-31 | Sequenom, Inc. | Mass spectrometric methods for sequencing nucleic acids |
US20040126895A1 (en) * | 1998-01-13 | 2004-07-01 | James W. Overbeck | Depositing fluid specimens on substrates, resulting ordered arrays, techniques for analysis of deposited arrays |
EP1671703A3 (en) * | 1998-03-19 | 2006-07-05 | Precision System Science Co., Ltd. | Method for making substances in carriers |
US6723564B2 (en) | 1998-05-07 | 2004-04-20 | Sequenom, Inc. | IR MALDI mass spectrometry of nucleic acids using liquid matrices |
FI107025B (en) * | 1998-06-10 | 2001-05-31 | Biohit Oyj | Suction device and method for removing the disposable tip |
FI107026B (en) * | 1998-08-26 | 2001-05-31 | Biohit Oyj | Suction device tip and method for dispensing fluid with a suction device |
US6132582A (en) * | 1998-09-14 | 2000-10-17 | The Perkin-Elmer Corporation | Sample handling system for a multi-channel capillary electrophoresis device |
EP1129346A2 (en) * | 1998-10-16 | 2001-09-05 | Intelligent Automation Systems | Continuous processing automated workstation |
US20040047765A1 (en) * | 1998-10-16 | 2004-03-11 | Gordon Steven J. | Automated robotic workstation and methods of operation thereof |
US6485692B1 (en) * | 1998-12-04 | 2002-11-26 | Symyx Technologies, Inc. | Continuous feed parallel reactor |
US6255116B1 (en) * | 1998-12-17 | 2001-07-03 | Smithkline Beecham Corporation | Apparatus and process for arraying beads |
AU2634600A (en) * | 1999-01-29 | 2000-08-18 | Genomic Instrumentation Services, Inc. | Pipetter |
US7101510B2 (en) * | 1999-02-16 | 2006-09-05 | Applera Corporation | Matrix storage and dispensing system |
US6432719B1 (en) * | 1999-02-16 | 2002-08-13 | Pe Corporation (Ny) | Matrix storage and dispensing system |
ATE341003T1 (en) * | 1999-02-16 | 2006-10-15 | Applera Corp | DEVICE FOR HANDLING BEADS |
US20020042046A1 (en) * | 1999-02-25 | 2002-04-11 | Vertex Pharmaceuticals, Incorporated | Crystallizable compositions comprising a hepatitis C virus NS3 protease domain/NS4A complex |
US6225061B1 (en) | 1999-03-10 | 2001-05-01 | Sequenom, Inc. | Systems and methods for performing reactions in an unsealed environment |
US6258324B1 (en) | 1999-03-15 | 2001-07-10 | Felix H. Yiu | Pipette dispensing block |
US20020009394A1 (en) | 1999-04-02 | 2002-01-24 | Hubert Koster | Automated process line |
US6143252A (en) * | 1999-04-12 | 2000-11-07 | The Perkin-Elmer Corporation | Pipetting device with pipette tip for solid phase reactions |
US6368562B1 (en) | 1999-04-16 | 2002-04-09 | Orchid Biosciences, Inc. | Liquid transportation system for microfluidic device |
US6485690B1 (en) * | 1999-05-27 | 2002-11-26 | Orchid Biosciences, Inc. | Multiple fluid sample processor and system |
JP2003519829A (en) | 1999-10-13 | 2003-06-24 | シークエノム・インコーポレーテツド | Methods for creating a database and a database for identifying polymorphic genetic markers |
US7917301B1 (en) | 2000-09-19 | 2011-03-29 | Sequenom, Inc. | Method and device for identifying a biological sample |
US6399024B1 (en) * | 2000-02-01 | 2002-06-04 | Incyte Genomics, Inc. | Multichannel pipette head |
US6438498B1 (en) * | 2000-02-10 | 2002-08-20 | I-Stat Corporation | System, method and computer implemented process for assaying coagulation in fluid samples |
US20020018999A1 (en) | 2000-02-24 | 2002-02-14 | Jan Henriksson | Methods for characterizing polymorphisms |
US6471917B1 (en) * | 2000-04-11 | 2002-10-29 | Affymax, Inc. | System and method for single or multiple bead distribution with an adjustable capillary |
US6958214B2 (en) * | 2000-07-10 | 2005-10-25 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
US6715369B2 (en) * | 2000-08-03 | 2004-04-06 | Nichiryo Co., Ltd. | Hybrid pipette |
US6550349B1 (en) * | 2000-09-19 | 2003-04-22 | Molecular Devices Corporation | Pipette tip holder |
KR100649342B1 (en) * | 2000-10-30 | 2006-11-27 | 시쿼넘, 인코포레이티드 | Method and apparatus for delivery of submicroliter volumes onto a substrate |
US20020102725A1 (en) | 2000-12-20 | 2002-08-01 | Eugene Zabarovsky | Nucleic acid encoding ion transporter component protein |
CA2436518A1 (en) * | 2001-01-30 | 2002-08-08 | Vertex Pharmaceuticals Incorporated | A quantitative assay for nucleic acids |
US20020104389A1 (en) * | 2001-02-08 | 2002-08-08 | Hovey Scott A. | Automated liquid handling device |
US20030036057A1 (en) | 2001-03-09 | 2003-02-20 | Andreas Braun | Genes and polymorphisms associated with cardiovascular disease and their use |
US20020155587A1 (en) | 2001-04-20 | 2002-10-24 | Sequenom, Inc. | System and method for testing a biological sample |
US6982063B2 (en) * | 2001-05-25 | 2006-01-03 | Matrix Technologies Corp | Automated pipetting system |
JP2005507078A (en) * | 2001-10-26 | 2005-03-10 | セクエノム, インコーポレイテッド | Method and apparatus for parallel distribution of a defined volume of solid particles |
-
2002
- 2002-10-25 JP JP2003538713A patent/JP2005507078A/en not_active Revoked
- 2002-10-25 WO PCT/US2002/034447 patent/WO2003036263A2/en active Application Filing
- 2002-10-25 US US10/281,428 patent/US7159740B2/en not_active Expired - Lifetime
- 2002-10-25 EP EP02784312A patent/EP1451674A4/en not_active Withdrawn
- 2002-10-25 WO PCT/US2002/034490 patent/WO2003035239A2/en not_active Application Discontinuation
- 2002-10-25 JP JP2003537815A patent/JP2005507074A/en active Pending
- 2002-10-25 EP EP02776351A patent/EP1450957A1/en not_active Withdrawn
- 2002-10-25 CA CA002464467A patent/CA2464467A1/en not_active Abandoned
- 2002-10-25 AU AU2002348099A patent/AU2002348099A1/en not_active Abandoned
- 2002-10-25 US US10/281,476 patent/US20030111494A1/en not_active Abandoned
- 2002-10-25 US US10/281,464 patent/US20030113233A1/en not_active Abandoned
- 2002-10-25 CA CA002464682A patent/CA2464682A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5798035A (en) * | 1996-10-03 | 1998-08-25 | Pharmacopeia, Inc. | High throughput solid phase chemical synthesis utilizing thin cylindrical reaction vessels useable for biological assay |
US5865224A (en) * | 1996-12-20 | 1999-02-02 | Life Technologies, Inc. | Method and apparatus for automated dispensing |
US6416718B1 (en) * | 1998-05-29 | 2002-07-09 | Ontogen Corporation | Sample wash station assembly |
US6432365B1 (en) * | 2000-04-14 | 2002-08-13 | Discovery Partners International, Inc. | System and method for dispensing solution to a multi-well container |
Non-Patent Citations (1)
Title |
---|
See also references of EP1451674A4 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9244069B2 (en) | 2009-07-29 | 2016-01-26 | Dynex Technologies | Sample plate systems and methods |
US9523701B2 (en) | 2009-07-29 | 2016-12-20 | Dynex Technologies, Inc. | Sample plate systems and methods |
CN103728198A (en) * | 2014-01-16 | 2014-04-16 | 深圳市华测检测技术股份有限公司 | Remote atmospheric particulate monitoring system |
CN103728198B (en) * | 2014-01-16 | 2016-08-17 | 华测检测认证集团股份有限公司 | Remotely atmosphere particle monitoring system |
Also Published As
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WO2003035239A3 (en) | 2003-10-16 |
EP1451674A4 (en) | 2008-08-20 |
CA2464467A1 (en) | 2003-05-01 |
JP2005507074A (en) | 2005-03-10 |
US20030111494A1 (en) | 2003-06-19 |
EP1450957A1 (en) | 2004-09-01 |
US7159740B2 (en) | 2007-01-09 |
US20030124735A1 (en) | 2003-07-03 |
CA2464682A1 (en) | 2003-05-01 |
EP1451674A2 (en) | 2004-09-01 |
US20030113233A1 (en) | 2003-06-19 |
WO2003036263A2 (en) | 2003-05-01 |
WO2003035239A2 (en) | 2003-05-01 |
JP2005507078A (en) | 2005-03-10 |
AU2002348099A1 (en) | 2003-05-06 |
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