WO2003028618A3 - Systems, methods and apparatuses for manufacturing dosage forms - Google Patents

Systems, methods and apparatuses for manufacturing dosage forms Download PDF

Info

Publication number
WO2003028618A3
WO2003028618A3 PCT/US2002/030570 US0230570W WO03028618A3 WO 2003028618 A3 WO2003028618 A3 WO 2003028618A3 US 0230570 W US0230570 W US 0230570W WO 03028618 A3 WO03028618 A3 WO 03028618A3
Authority
WO
WIPO (PCT)
Prior art keywords
die cavity
dosage forms
apparatuses
systems
methods
Prior art date
Application number
PCT/US2002/030570
Other languages
French (fr)
Other versions
WO2003028618A2 (en
Inventor
Joseph Luber
Harry S Sowden
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Priority to AU2002334684A priority Critical patent/AU2002334684A1/en
Priority to MXPA04002970A priority patent/MXPA04002970A/en
Priority to CA002461856A priority patent/CA2461856A1/en
Priority to JP2003531955A priority patent/JP2005504588A/en
Priority to DE60223938T priority patent/DE60223938T2/en
Priority to KR10-2004-7004661A priority patent/KR20040039453A/en
Priority to EP02800364A priority patent/EP1436141B1/en
Publication of WO2003028618A2 publication Critical patent/WO2003028618A2/en
Publication of WO2003028618A3 publication Critical patent/WO2003028618A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/02—Apparatus specially adapted for manufacture or treatment of sweetmeats or confectionery; Accessories therefor
    • A23G3/04—Sugar-cookers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/34—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses for coating articles, e.g. tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/0082—Dust eliminating means; Mould or press ram cleaning means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/04—Frames; Guides
    • B30B15/044—Means preventing deflection of the frame, especially for C-frames
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/04—Frames; Guides
    • B30B15/047—C-shaped frames
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/30—Feeding material to presses
    • B30B15/302—Feeding material in particulate or plastic state to moulding presses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/32—Discharging presses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2873—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Abstract

Method and apparatus for forming compressed dosage forms, comprising: a) placing a supply of powder in flow communication with a die, said die comprising a die cavity therein in flow communication with a filter; b) applying suction to said die cavity so as to cause powder to flow into said die cavity, said suction being applied to said die cavity through said filter; c) isolating said filter from said powder in said die cavity; and d) compressing said powder in said die cavity so as to form a compressed dosage form while said filter is isolated therefrom.
PCT/US2002/030570 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms WO2003028618A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2002334684A AU2002334684A1 (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms
MXPA04002970A MXPA04002970A (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms.
CA002461856A CA2461856A1 (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms
JP2003531955A JP2005504588A (en) 2001-09-28 2002-09-26 System, method and apparatus for producing dosage forms
DE60223938T DE60223938T2 (en) 2001-09-28 2002-09-26 SYSTEMS, METHODS AND DEVICES FOR MANUFACTURING DOSAGE FORMS
KR10-2004-7004661A KR20040039453A (en) 2001-09-28 2002-09-26 Systems, methods, and apparatus for manufacturing dosage forms
EP02800364A EP1436141B1 (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/966,509 2001-09-28
US09/966,509 US6767200B2 (en) 2001-09-28 2001-09-28 Systems, methods and apparatuses for manufacturing dosage forms

Publications (2)

Publication Number Publication Date
WO2003028618A2 WO2003028618A2 (en) 2003-04-10
WO2003028618A3 true WO2003028618A3 (en) 2003-08-14

Family

ID=25511515

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/030570 WO2003028618A2 (en) 2001-09-28 2002-09-26 Systems, methods and apparatuses for manufacturing dosage forms

Country Status (12)

Country Link
US (3) US6767200B2 (en)
EP (2) EP1880717A3 (en)
JP (1) JP2005504588A (en)
KR (1) KR20040039453A (en)
CN (3) CN1299894C (en)
AT (1) ATE380109T1 (en)
AU (1) AU2002334684A1 (en)
CA (1) CA2461856A1 (en)
DE (1) DE60223938T2 (en)
ES (1) ES2297046T3 (en)
MX (1) MXPA04002970A (en)
WO (1) WO2003028618A2 (en)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0212951A (en) * 2001-09-28 2004-10-26 Mcneil Ppc Inc Composite Dosage Forms
US20040146559A1 (en) * 2002-09-28 2004-07-29 Sowden Harry S. Dosage forms having an inner core and outer shell with different shapes
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
US6767200B2 (en) * 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
JP5054921B2 (en) * 2004-02-05 2012-10-24 太陽化学株式会社 Adsorbability imparting agent containing porous silica
US20050196442A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196446A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
US20050196448A1 (en) * 2004-03-05 2005-09-08 Hai Yong Huang Polymeric compositions and dosage forms comprising the same
US20050196447A1 (en) * 2004-03-05 2005-09-08 Huang Hai Y. Polymeric compositions and dosage forms comprising the same
ITMO20040248A1 (en) * 2004-09-24 2004-12-24 Sacmi Cooperativa Meccanici Imola Scarl OPERATING MACHINE EQUIPPED WITH A MULTIPLE OF APPARATUS ACTUATORS AND CONTROL SYSTEM.
US20060088587A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088586A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070281022A1 (en) * 2004-10-27 2007-12-06 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070190133A1 (en) * 2004-10-27 2007-08-16 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US8383159B2 (en) * 2004-10-27 2013-02-26 Mcneil-Ppc, Inc. Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060087051A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088593A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060093560A1 (en) * 2004-10-29 2006-05-04 Jen-Chi Chen Immediate release film coating
US7404708B2 (en) * 2004-12-07 2008-07-29 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
US7530804B2 (en) * 2004-12-07 2009-05-12 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
US9579238B2 (en) 2005-02-17 2017-02-28 The Procter & Gamble Company Sanitary napkins capable of taking complex three-dimensional shape in use
US8211078B2 (en) 2005-02-17 2012-07-03 The Procter And Gamble Company Sanitary napkins capable of taking complex three-dimensional shape in use
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US20060233882A1 (en) * 2005-04-15 2006-10-19 Sowden Harry S Osmotic dosage form
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
US20060286148A1 (en) * 2005-05-18 2006-12-21 Ppd, Inc. Method of forming implants
US20070048366A1 (en) * 2005-08-26 2007-03-01 Jen-Chi Chen Gelatin-based coatings having improved durability
DE102005061787A1 (en) * 2005-12-23 2007-06-28 Fette Gmbh Device for generating a negative pressure in the sealed space of a tablet press and / or an insulator
JP4506734B2 (en) * 2006-03-31 2010-07-21 Ｔｄｋ株式会社 Molding equipment
US7630787B2 (en) * 2006-04-19 2009-12-08 Husky Injection Molding Systems Ltd System for integrating insert with molded article
US20080075766A1 (en) * 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
US20080122141A1 (en) * 2006-11-29 2008-05-29 Bryan Bedal Sinterable Powder
EP1952696A1 (en) * 2007-02-01 2008-08-06 Nestec S.A. A method and apparatus for making centre-filled shaped food products
US20090060983A1 (en) * 2007-08-30 2009-03-05 Bunick Frank J Method And Composition For Making An Orally Disintegrating Dosage Form
JP5098535B2 (en) * 2007-09-21 2012-12-12 東洋製罐株式会社 Molten resin feeder
ES2633449T3 (en) * 2007-10-31 2017-09-21 Johnson & Johnson Consumer Inc. Orally disintegrable dose form
DE102007057791B4 (en) * 2007-11-30 2010-12-16 Fette Gmbh Rotary press
CA2709709A1 (en) * 2007-12-21 2009-07-09 Mcneil-Ppc, Inc. Manufacture of tablet
US8771643B2 (en) 2008-01-04 2014-07-08 Schabar Research Associates Llc Use of analgesic potentiating compounds to potentiate the analgesic properties of an analgesic compound
US20090218714A1 (en) * 2008-02-29 2009-09-03 Ping Li Apparatus
ES2605615T3 (en) * 2008-04-18 2017-03-15 Korsch Ag Device for inserting inlays into the dies of a rotary tablet press
EP2309999A1 (en) * 2008-06-26 2011-04-20 McNeil-PPC, Inc. Coated particles containing pharmaceutically active agents
WO2010006029A2 (en) 2008-07-08 2010-01-14 Hyperbranch Medical Technology, Inc. Self-contained medical applicators for multiple component formulations, and methods of use thereof
US8383632B2 (en) * 2008-09-05 2013-02-26 Mcneil-Ppc, Inc. Method for making cetirizine tablets
US20100112052A1 (en) * 2008-10-31 2010-05-06 Vincent Chen Osmotic tablet with a compressed outer coating
US8246988B2 (en) * 2009-01-05 2012-08-21 Mcneil-Ppc, Inc. Three layer tablet containing cetirizine, pseudoephedrine, and naproxen
CA2748728C (en) 2009-01-05 2017-01-03 Mcneil-Ppc, Inc. Tablet containing cetirizine, pseudoephedrine, and naproxen containing a barrier layer
US8252330B2 (en) * 2009-01-05 2012-08-28 Mcneil-Ppc, Inc. Tablet containing coated particles of cetirizine, pseudoephedrine, and/or naproxen
CN102341101A (en) * 2009-01-06 2012-02-01 普罗秋斯生物医学公司 High-throughput production of ingestible event markers
US8381896B2 (en) * 2009-04-13 2013-02-26 Ackley Machine Corporation Ejection system
NZ619375A (en) 2009-04-28 2015-03-27 Proteus Digital Health Inc Highly reliable ingestible event markers and methods for using the same
RU2012102772A (en) 2009-06-29 2013-08-10 МакНЕЙЛ-ППС, ИНК. PHARMACEUTICAL TABLET CONTAINING A FILLED FILLED CAPSULE
US8871263B2 (en) 2009-09-24 2014-10-28 Mcneil-Ppc, Inc. Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US20110070286A1 (en) * 2009-09-24 2011-03-24 Andreas Hugerth Process for the manufacture of nicotine-comprising chewing gum and nicotine-comprising chewing gum manufactured according to said process
IT1397691B1 (en) * 2009-12-22 2013-01-24 Mg 2 Srl INTERMITTENT ROTARY MACHINE FOR FILLING CAPSULES WITH PHARMACEUTICALS.
RU2012143791A (en) 2010-04-07 2014-05-20 Проутьюс Диджитал Хэлс, Инк. MINIATURE INGESTED DEVICE
IT1400396B1 (en) * 2010-06-08 2013-05-31 Perfetti Van Melle Spa METHOD AND PLANT FOR COATING OF EDIBLE PRODUCTS.
EP2618812B1 (en) * 2010-09-22 2018-10-17 Johnson & Johnson Consumer Inc. Multi-layered orally disintegrating tablet and the manufacture thereof
WO2012039789A1 (en) 2010-09-22 2012-03-29 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
EP2618813A1 (en) 2010-09-22 2013-07-31 McNeil-PPC, Inc. Manufacture of tablets from energy-applied powder blend
JP2012076816A (en) * 2010-10-05 2012-04-19 Takazono Technology Inc Medicine feeder
JP2014504902A (en) 2010-11-22 2014-02-27 プロテウス デジタル ヘルス， インコーポレイテッド Ingestible device with medicinal product
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
CA2851206A1 (en) * 2011-10-04 2013-04-11 Kikusui Seisakusho Ltd. Powdery material filling device with redundant powdery material recovering mechanism and rotary compression molding machine
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US8545878B1 (en) 2012-11-09 2013-10-01 Civitas Therapeutics, Inc. Capsules containing high doses of levodopa for pulmonary use
BR112015010601B1 (en) * 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. PHARMACEUTICAL COMPOSITION AND USE OF THE COMPOSITION
WO2014120669A1 (en) 2013-01-29 2014-08-07 Proteus Digital Health, Inc. Highly-swellable polymeric films and compositions comprising the same
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
ES2750323T3 (en) 2014-01-10 2020-03-25 Johnson & Johnson Consumer Inc Method for manufacturing a tablet using radio frequency and loss coated particles
EP3140110B1 (en) * 2014-05-07 2020-03-18 Korsch AG Pressure roller station for rotary presses having two pressure roller axles for receiving pressure rollers
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
TWI580310B (en) * 2015-08-14 2017-04-21 Bottle-Top Dev Co Microwave heating system
EP3222414B1 (en) * 2016-03-24 2019-07-17 Korsch AG Rotation press with stamps with at least two stamp tips at staggered heights for carrying out multiple pressing processes during a rotation
BR112019000861B1 (en) 2016-07-22 2020-10-27 Proteus Digital Health, Inc electronic device
TWI735689B (en) 2016-10-26 2021-08-11 日商大塚製藥股份有限公司 Methods for manufacturing capsules with ingestible event markers
WO2018098434A1 (en) 2016-11-28 2018-05-31 Johnson & Johnson Consumer Inc. Process for making a coated dosage form
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
DE102017125986A1 (en) * 2017-11-07 2019-05-09 Theegarten-Pactec Gmbh & Co. Kg Method and device for transporting compressed files
CN108000929A (en) * 2017-12-11 2018-05-08 上海天和制药机械有限公司 A kind of rotation table device of rotary tablet machine
CN109435315B (en) * 2018-11-09 2023-06-23 苏州益顺华智能装备有限公司 Full-automatic cake gluing machine
CN110406703B (en) * 2019-08-05 2023-06-13 双洎能源(洛阳)有限公司 Carbon package filling machine for lithium battery
IL299845A (en) 2020-07-15 2023-03-01 Schabar Res Associates Llc Unit oral dose compositions composed of ibuprofen and famotidine for the treatment of acute pain and the reduction of the severity and/or risk of heartburn
CA3124579A1 (en) 2020-07-15 2022-01-15 Schabar Research Associates Llc Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn
CN112739043B (en) * 2020-11-27 2022-04-12 惠州市特创电子科技股份有限公司 Deep etching hole control device of circuit board and preparation method of circuit board
CN112976199B (en) * 2021-03-30 2023-03-28 霍邱县淮美奇工艺品有限公司 Reed tabletting tool for processing wicker products
CN113813184A (en) * 2021-09-22 2021-12-21 王义峰 Probiotic tablet preparation system and preparation method
CN113878778B (en) * 2021-10-09 2023-07-07 河北雄安张氏丹栋新能源科技有限公司 Equipment for preparing polylactic acid embryo material
CN114006135B (en) * 2021-10-25 2023-07-14 苏州工业园区源荣科创机电有限公司 Electric vacuum integrated priming device
WO2023222688A1 (en) * 2022-05-18 2023-11-23 Korsch Ag Device for inserting at least one object into at least one die of a tabletting machine
CN115494100B (en) * 2022-11-17 2023-03-14 济南弗莱德科技有限公司 Online oil analyzer

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3029752A (en) * 1959-07-20 1962-04-17 Stokes F J Corp Tablet making machine
GB1235926A (en) * 1967-07-13 1971-06-16 Usm Corp Improvements in or relating to methods and apparatus suitable for use in forming pellets
US4292017A (en) * 1980-07-09 1981-09-29 Doepel Wallace A Apparatus for compressing tablets
JPS57200502A (en) * 1981-06-02 1982-12-08 Yoshitsuka Seiki:Kk Vacuum powder molding method
JPS62230500A (en) * 1986-04-01 1987-10-09 Kyowa Hakko Kogyo Co Ltd Mortar for compression molding
JPH06179098A (en) * 1992-12-09 1994-06-28 Kao Corp Die and method for powder compression molding

Family Cites Families (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US545832A (en) * 1895-09-03 Machine for compressing and molding popcorn
US599865A (en) 1898-03-01 Emanuel l
US1036647A (en) * 1911-06-19 1912-08-27 St Louis Briquette Machine Company Briquet-machine.
US1900012A (en) * 1925-09-04 1933-03-07 Western Cartridge Co Process of and apparatus for making wads
US2307371A (en) 1941-08-13 1943-01-05 Ray O Vac Co Molding process
US3183570A (en) * 1960-03-21 1965-05-18 Clarence W Vogt Compacting equipment
GB1212535A (en) * 1966-10-12 1970-11-18 Shionogi & Co Method and apparatus for producing molded article
US3605479A (en) * 1968-05-08 1971-09-20 Textron Inc Forming press
US3677673A (en) * 1970-08-25 1972-07-18 Pennwalt Corp Rotary press
US3832252A (en) 1970-09-29 1974-08-27 T Higuchi Method of making a drug-delivery device
US3726622A (en) 1971-08-20 1973-04-10 Wolverine Pentronix Compacting apparatus
DE2157465C3 (en) 1971-11-19 1975-04-24 Werner & Pfleiderer, 7000 Stuttgart Filling device for a hydraulic block press
DE2257828C2 (en) * 1972-11-25 1974-01-17 Bochumer Eisenhuette Heintzmann & Co, 4630 Bochum Device for the shield-like expansion of underground mining operations
US3912441A (en) * 1972-12-13 1975-10-14 Yasuo Shimada Compressing roll in rotary power compression molding machine
DE2363921A1 (en) * 1973-12-19 1975-07-03 Korsch Spezialfab Emil Revolving tablet press - has working region completely surrounded by cabin with air filter and dust aspiration
US3891375A (en) * 1974-01-21 1975-06-24 Vector Corp Tablet press
DE2462379A1 (en) * 1974-07-23 1976-12-02 Chem Fab Rottendorf Gmbh Dust extraction for tablet manufacture - uses central dust extraction system operated by vacuum with connected central filter system
GB1548022A (en) 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
SU1131676A1 (en) * 1977-12-22 1984-12-30 Ждановский Завод Технологического Оборудования Медицинской Промышленности Rotary tabletting machine
NL7906689A (en) 1979-09-06 1981-03-10 Dawsonville Corp Nv TATTOO.
US4473526A (en) 1980-01-23 1984-09-25 Eugen Buhler Method of manufacturing dry-pressed molded articles
US4362493A (en) * 1980-07-09 1982-12-07 Doepel Wallace A Apparatus for compressing tablets
DE3144678A1 (en) 1981-11-10 1983-05-19 Eugen Dipl.-Ing. 8871 Burtenbach Bühler METHOD AND DEVICE FOR THE PRODUCTION OF MOLDINGS FROM A GIANT CAPABILITY
US4781714A (en) 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
NL194820C (en) 1983-11-02 2003-04-03 Alza Corp Preparation for the release of a heat-reacting composition.
AU591171B2 (en) 1983-11-02 1989-11-30 Alza Corporation Dispenser for delivering thermo-responsive composition
DE3404108A1 (en) 1984-02-07 1985-08-14 Kilian & Co GmbH, 5000 Köln TABLET PRESS
US4518335A (en) 1984-03-14 1985-05-21 Allied Corporation Dilatant mold and dilatant molding apparatus
JPS60217106A (en) 1984-04-12 1985-10-30 高橋　信之 Inorganic-powder freezing molding method
CN85204144U (en) * 1985-10-03 1986-08-20 河南省巩县站街减速机厂 Honeycomb briquet-forming machine
US5229164A (en) 1985-12-19 1993-07-20 Capsoid Pharma Gmbh Process for producing individually dosed administration forms
JPS62230600A (en) 1986-03-31 1987-10-09 東洋ゴム工業株式会社 Forklift with expansible fork
FR2602907B1 (en) * 1986-08-05 1988-11-25 Sprague France CAPACITOR ANODE, MANUFACTURING METHOD THEREOF, AND CAPACITOR COMPRISING THE SAME
CA1290526C (en) 1986-11-07 1991-10-15 Marianne Wieser Mold and die operation
US4820524A (en) 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
US4813818A (en) 1987-08-25 1989-03-21 Michael Sanzone Apparatus and method for feeding powdered materials
US4851226A (en) 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
IT1221567B (en) * 1987-12-30 1990-07-12 Ima Spa COMPRESSING MACHINE FOR THE PRODUCTION OF TABLETS
US5146730A (en) 1989-09-20 1992-09-15 Banner Gelatin Products Corp. Film-enrobed unitary-core medicament and the like
US5213738A (en) 1990-05-15 1993-05-25 L. Perrigo Company Method for making a capsule-shaped tablet
US5089270A (en) 1990-05-15 1992-02-18 L. Perrigo Company Capsule-shaped tablet
US5075114A (en) 1990-05-23 1991-12-24 Mcneil-Ppc, Inc. Taste masking and sustained release coatings for pharmaceuticals
US5464631A (en) 1990-06-27 1995-11-07 Warner-Lambert Company Encapsulated dosage forms
US5503673A (en) 1990-11-05 1996-04-02 Mcneil-Ppc, Inc Apparatus for dip coating product
US5538125A (en) 1990-11-05 1996-07-23 Mcneil-Ppc, Inc. Indexing and feeding systems for apparatus for gelatin coating tablets
US5228916A (en) 1990-11-05 1993-07-20 Mcneil-Ppc, Inc. Apparatus for creating a gelatin coating
US5436026A (en) 1990-11-05 1995-07-25 Mcneil-Ppc, Inc. Discharge and transfer system for apparatus for gelatin coating tablets
US5273758A (en) * 1991-03-18 1993-12-28 Sandoz Ltd. Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms
US5158728A (en) * 1991-04-12 1992-10-27 Elizabeth-Hata International, Inc. Multi-layer medicinal tablet forming machine and method for using the same
DE4118542A1 (en) * 1991-06-06 1992-12-10 Agfa Gevaert Ag PHOTOGRAPHIC SILVER HALOGEN EMULSION
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5200191A (en) 1991-09-11 1993-04-06 Banner Gelatin Products Corp. Softgel manufacturing process
US5200195A (en) 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
JP2735983B2 (en) 1992-04-23 1998-04-02 花王株式会社 Resin powder and cosmetics
DE4218122C1 (en) * 1992-06-02 1994-01-20 Fette Wilhelm Gmbh Process for pressing two-layer tablets in a double rotary press and device for carrying out the process
JPH0617096A (en) 1992-07-01 1994-01-25 Asahi Glass Co Ltd Solvent mixture composition
US5317849A (en) 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
WO1994007470A1 (en) 1992-09-30 1994-04-14 Pfizer Inc. Article containing a core and a coating having a non constant thickness
JP2524955B2 (en) 1993-04-22 1996-08-14 トーワ株式会社 Method and apparatus for resin sealing molding of electronic parts
CN2164355Y (en) * 1993-06-09 1994-05-11 苏州市煤炭实业公司 Moulding device for honeycomb briquet moulding machine
US5415868A (en) 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
US5648033A (en) * 1993-09-10 1997-07-15 Fuisz Technologies Ltd. Method and apparatus for retaining a formed compression dosage unit within a die cavity
US5672364A (en) * 1994-07-07 1997-09-30 Sankyo Seisakusho Co. & Eisai Co., Ltd. Apparatus for manufacturing tablets
US5614578A (en) 1994-10-28 1997-03-25 Alza Corporation Injection-molded dosage form
KR19990008430A (en) 1995-05-09 1999-01-25 피터 존스 팔슨즈 Powder coating composition for electrostatic coating of medicines
US5667158A (en) * 1995-05-23 1997-09-16 Glaxo Wellcome Inc. Automated blend reclaim system for pharmaceutical tablet compression machine
US5824338A (en) 1996-08-19 1998-10-20 L. Perrigo Company Caplet and gelatin covering therefor
DE19710213A1 (en) 1997-03-12 1998-09-17 Basf Ag Process for the manufacture of solid combination dosage forms
US5837301A (en) 1997-04-28 1998-11-17 Husky Injection Molding Systems Ltd. Injection molding machine having a high speed turret
ES2235337T3 (en) 1997-07-09 2005-07-01 Swiss Caps Rechte Und Lizenzen Ag PROCEDURE AND DEVICE FOR MANUFACTURING A MULTI-PATH PHARMACEUTICAL FORM, PHYSIOLOGICALLY TOLERABLE.
US5942034A (en) 1997-07-24 1999-08-24 Bayer Corporation Apparatus for the gelatin coating of medicaments
DE19840256A1 (en) 1998-09-03 2000-03-09 Basf Ag Widely applicable, continuous method for preparing coated solid dosage forms, comprises extruding mixture of drug and thermoplastic binder then applying coating composition in liquid or vapor form
US5997905A (en) 1998-09-04 1999-12-07 Mcneil-Ppc Preparation of pharmaceutically active particles
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
GB0120835D0 (en) 2001-08-28 2001-10-17 Smithkline Beecham Plc Process
US6767200B2 (en) * 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6706226B2 (en) * 2002-07-16 2004-03-16 Eastman Kodak Company Compacting moisture-sensitive organic materials in making an organic light-emitting device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3029752A (en) * 1959-07-20 1962-04-17 Stokes F J Corp Tablet making machine
GB1235926A (en) * 1967-07-13 1971-06-16 Usm Corp Improvements in or relating to methods and apparatus suitable for use in forming pellets
US4292017A (en) * 1980-07-09 1981-09-29 Doepel Wallace A Apparatus for compressing tablets
JPS57200502A (en) * 1981-06-02 1982-12-08 Yoshitsuka Seiki:Kk Vacuum powder molding method
JPS62230500A (en) * 1986-04-01 1987-10-09 Kyowa Hakko Kogyo Co Ltd Mortar for compression molding
JPH06179098A (en) * 1992-12-09 1994-06-28 Kao Corp Die and method for powder compression molding

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 007, no. 050 (M - 197) 26 February 1983 (1983-02-26) *
PATENT ABSTRACTS OF JAPAN vol. 012, no. 091 (M - 679) 24 March 1988 (1988-03-24) *
PATENT ABSTRACTS OF JAPAN vol. 018, no. 514 (M - 1680) 28 September 1994 (1994-09-28) *

Also Published As

Publication number Publication date
EP1880717A3 (en) 2008-02-20
US20030072799A1 (en) 2003-04-17
DE60223938T2 (en) 2008-11-27
CN1596186A (en) 2005-03-16
JP2005504588A (en) 2005-02-17
EP1880717A2 (en) 2008-01-23
ES2297046T3 (en) 2008-05-01
US7323129B2 (en) 2008-01-29
US20040126425A1 (en) 2004-07-01
US6767200B2 (en) 2004-07-27
MXPA04002970A (en) 2005-06-20
DE60223938D1 (en) 2008-01-17
CN1299894C (en) 2007-02-14
AU2002334684A1 (en) 2003-04-14
EP1436141B1 (en) 2007-12-05
EP1436141A2 (en) 2004-07-14
US20040137057A1 (en) 2004-07-15
KR20040039453A (en) 2004-05-10
ATE380109T1 (en) 2007-12-15
CN101032446A (en) 2007-09-12
CN101032446B (en) 2010-09-29
CA2461856A1 (en) 2003-04-10
CN1864668A (en) 2006-11-22
US7361006B2 (en) 2008-04-22
WO2003028618A2 (en) 2003-04-10

Similar Documents

Publication Publication Date Title
WO2003028618A3 (en) Systems, methods and apparatuses for manufacturing dosage forms
AU2003212175A1 (en) Method and apparatus for compressing a gas to a high pressure
TWI264763B (en) Load-lock technique
AU2003212470A1 (en) Method and process for signaling, communication and administration of networked objects
AU5578400A (en) Disintegrative core for high pressure casting, method for manufacturing the same, and method for extracting the same
WO2003013738A3 (en) Method and device for the simultaneous coating and moulding of a body
HK1072757A1 (en) Method and apparatus for introducing powder into apocket
GB0119652D0 (en) Surgical implant
AU2003302592A1 (en) Ceramic filter and its producing method
WO2003011793A3 (en) Method for manufacturing sintered magnet
AU2179601A (en) Method and device for modifying compression rate to optimize operating conditions of reciprocating piston engines
TWI317771B (en) Process for manufacturing cellulose molding, plant component extracting apparatus, and process for producing cellulose acetate
TW332798B (en) The method and apparatus for manufacturing synchronous transmission belt
AU2003211570A1 (en) Exhaust emission control system, method of calculating pressure loss of filter, and method of manufacturing filter
AU2003289247A1 (en) Composite cured silicone powder, method for production thereof and aqueous composition
WO2007059012A3 (en) Enhanced plasma filter
WO2006072073A3 (en) Spiked axisymmetric nozzle and process of using the same
PL362072A1 (en) Method of fabrication of filter elements, filter element, appliance for fabrication of filter elements and machine for manufacture of filter elements
WO2005032988A3 (en) Method and apparatus for making an absorbent composite
WO2003045611A1 (en) Method and apparatus for producing granulated powder of rare earth alloy and method for producing rare earth alloy sintered compact
AU2002357504A1 (en) Device and method for handling lase-of-polymerization substance, device for extracting liquid from device under reduced pressure, and method of manufacturing lase-of-polymerization substance
SI1690830T1 (en) Method of preparing an easily-dispersed rheology-grade product from a pseudolaminar silicate, product thus obtained and methods of using same
AU2001244679A1 (en) Method for wet forming of powder, method for producing powder sintered compact, powdery sintered compact, and apparatus using powdery sintered compact
EP1240933A3 (en) Production method and apparatus for filter, forming die for filter, forming assembly for forming filter, and filter
HK1063902A1 (en) Grouping apparatus, grouping method and grouping program of communication devices

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2461856

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: PA/a/2004/002970

Country of ref document: MX

Ref document number: 2003531955

Country of ref document: JP

Ref document number: 1020047004661

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2002800364

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 20028236343

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2002800364

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2002800364

Country of ref document: EP