WO2003026482A3 - System and methods for performing surgical procedures and assessments - Google Patents

System and methods for performing surgical procedures and assessments Download PDF

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Publication number
WO2003026482A3
WO2003026482A3 PCT/US2002/030617 US0230617W WO03026482A3 WO 2003026482 A3 WO2003026482 A3 WO 2003026482A3 US 0230617 W US0230617 W US 0230617W WO 03026482 A3 WO03026482 A3 WO 03026482A3
Authority
WO
WIPO (PCT)
Prior art keywords
nerve
assessments
surgical
surgical procedures
methods
Prior art date
Application number
PCT/US2002/030617
Other languages
French (fr)
Other versions
WO2003026482A2 (en
WO2003026482A9 (en
Inventor
James Gharib
Norbert Kaula
Jeffrey Di Blewett
Allen Farquhar
Eric Finley
Jamil Elbanna
Scot Martinelli
Original Assignee
Nuvasive Inc
James Gharib
Norbert Kaula
Allen Farquhar
Eric Finley
Jamil Elbanna
Scot Martinelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23267823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2003026482(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nuvasive Inc, James Gharib, Norbert Kaula, Allen Farquhar, Eric Finley, Jamil Elbanna, Scot Martinelli filed Critical Nuvasive Inc
Priority to EP02778359A priority Critical patent/EP1435828A4/en
Priority to JP2003530128A priority patent/JP2005503857A/en
Publication of WO2003026482A2 publication Critical patent/WO2003026482A2/en
Publication of WO2003026482A3 publication Critical patent/WO2003026482A3/en
Priority to US10/809,280 priority patent/US7522953B2/en
Publication of WO2003026482A9 publication Critical patent/WO2003026482A9/en
Priority to US11/652,705 priority patent/US9259144B2/en
Priority to US12/423,559 priority patent/US8005535B2/en
Priority to US12/426,792 priority patent/US8027716B2/en
Priority to US12/628,549 priority patent/US8000782B2/en
Priority to US13/210,977 priority patent/US8265744B2/en
Priority to US13/215,791 priority patent/US8244343B2/en
Priority to US13/466,398 priority patent/US8672840B2/en
Priority to US13/568,236 priority patent/US8548579B2/en
Priority to US13/762,624 priority patent/US8768450B2/en
Priority to US13/763,816 priority patent/US8738123B2/en
Priority to US14/278,862 priority patent/US8977352B2/en
Priority to US14/618,438 priority patent/US10507120B2/en
Priority to US15/424,612 priority patent/US20170143515A1/en
Priority to US15/424,492 priority patent/US20170143514A1/en
Priority to US16/692,270 priority patent/US20200085590A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/32—Devices for opening or enlarging the visual field, e.g. of a tube of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/0218—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors for minimally invasive surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/25—User interfaces for surgical systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4887—Locating particular structures in or on the body
    • A61B5/4893—Nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6828—Leg
    • A—HUMAN NECESSITIES
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    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6831—Straps, bands or harnesses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0553—Paddle shaped electrodes, e.g. for laminotomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36142—Control systems for improving safety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37235—Aspects of the external programmer
    • A61N1/37247—User interfaces, e.g. input or presentation means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00039—Electric or electromagnetic phenomena other than conductivity, e.g. capacity, inductivity, Hall effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00199—Electrical control of surgical instruments with a console, e.g. a control panel with a display
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A61B17/025—Joint distractors
    • A61B2017/0256—Joint distractors for the spine
    • A61B2017/0262—Joint distractors for the spine with a provision for protecting nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046—Tracking techniques
    • A61B2034/2051—Electromagnetic tracking systems
    • A61B2034/2053—Tracking an applied voltage gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2072—Reference field transducer attached to an instrument or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2002/4635—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor using minimally invasive surgery

Abstract

The present invention involves systems (20) and related methods for performing surgical procedures and assessments, including the use of neurophysiology-based monitoring to: (a) determine nerve proximity and nerve direction to surgical instruments (30) employed in accessing a surgical target site; (b) assess the pathology (health or status) of a nerve or nerve root before, during, or after a surgical procedure; and/or (c) assess pedicle integrity before, during or after pedicle screw placement, all in an automated, easy to use, and easy to interpret fashion so as to provide a surgeon-driven system.
PCT/US2002/030617 2001-09-25 2002-09-25 System and methods for performing surgical procedures and assessments WO2003026482A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
EP02778359A EP1435828A4 (en) 2001-09-25 2002-09-25 System and methods for performing surgical procedures and assessments
JP2003530128A JP2005503857A (en) 2001-09-25 2002-09-25 Systems and methods for performing surgical procedures and surgical diagnosis
US10/809,280 US7522953B2 (en) 2001-09-25 2004-03-25 System and methods for performing surgical procedures and assessments
US11/652,705 US9259144B2 (en) 2002-07-11 2007-01-12 Surgical access system and related methods
US12/423,559 US8005535B2 (en) 2001-09-25 2009-04-14 System and methods for performing surgical procedures and assessments
US12/426,792 US8027716B2 (en) 2001-09-25 2009-04-20 System and methods for performing surgical procedures and assessments
US12/628,549 US8000782B2 (en) 2001-09-25 2009-12-01 System and methods for performing surgical procedures and assessments
US13/210,977 US8265744B2 (en) 2001-09-25 2011-08-16 Systems and methods for performing surgical procedures and assessments
US13/215,791 US8244343B2 (en) 2001-09-25 2011-08-23 System and methods for performing surgical procedures and assessments
US13/466,398 US8672840B2 (en) 2002-06-26 2012-05-08 Surgical access system and related methods
US13/568,236 US8548579B2 (en) 2001-09-25 2012-08-07 System and methods for performing surgical procedures and assessments
US13/762,624 US8768450B2 (en) 2001-09-25 2013-02-08 System and methods for performing surgical procedures and assessments
US13/763,816 US8738123B2 (en) 2001-09-25 2013-02-11 System and methods for performing surgical procedures and assessments
US14/278,862 US8977352B2 (en) 2001-09-25 2014-05-15 Systems and methods for performing surgical procedures and assessments
US14/618,438 US10507120B2 (en) 2001-09-25 2015-02-10 Systems and methods for performing surgical procedures and assessments
US15/424,612 US20170143515A1 (en) 2001-09-25 2017-02-03 Systems and methods for performing surgical procedures and assessments
US15/424,492 US20170143514A1 (en) 2001-09-25 2017-02-03 Systems and methods for performing surgical procedures and assessments
US16/692,270 US20200085590A1 (en) 2001-09-25 2019-11-22 Systems and methods for performing surgical procedures and assessments

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32542401P 2001-09-25 2001-09-25
US60/325,424 2001-09-25

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/809,280 Continuation US7522953B2 (en) 2001-09-25 2004-03-25 System and methods for performing surgical procedures and assessments

Publications (3)

Publication Number Publication Date
WO2003026482A2 WO2003026482A2 (en) 2003-04-03
WO2003026482A3 true WO2003026482A3 (en) 2003-10-23
WO2003026482A9 WO2003026482A9 (en) 2004-05-06

Family

ID=23267823

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/030617 WO2003026482A2 (en) 2001-09-25 2002-09-25 System and methods for performing surgical procedures and assessments

Country Status (4)

Country Link
US (14) US7522953B2 (en)
EP (2) EP1435828A4 (en)
JP (1) JP2005503857A (en)
WO (1) WO2003026482A2 (en)

Cited By (3)

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US8005535B2 (en) 2001-09-25 2011-08-23 Nuvasive, Inc. System and methods for performing surgical procedures and assessments
US9014776B2 (en) 1998-12-23 2015-04-21 Nuvasive, Inc. Surgical access and nerve surveillance
US9492151B2 (en) 2005-10-15 2016-11-15 Amendia, Inc. Multiple pathways for spinal nerve root decompression from a single access point

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CA2591678C (en) 1999-03-07 2008-05-20 Active Implants Corporation Method and apparatus for computerized surgery
WO2001037728A1 (en) 1999-11-24 2001-05-31 Nuvasive, Inc. Electromyography system
US6466817B1 (en) * 1999-11-24 2002-10-15 Nuvasive, Inc. Nerve proximity and status detection system and method
EP1289415A4 (en) * 2000-05-18 2008-12-03 Nuvasive Inc Tissue discrimination and applications in medical procedures
WO2003005887A2 (en) 2001-07-11 2003-01-23 Nuvasive, Inc. System and methods for determining nerve proximity, direction, and pathology during surgery
US7664544B2 (en) 2002-10-30 2010-02-16 Nuvasive, Inc. System and methods for performing percutaneous pedicle integrity assessments
US8147421B2 (en) 2003-01-15 2012-04-03 Nuvasive, Inc. System and methods for determining nerve direction to a surgical instrument
US7582058B1 (en) 2002-06-26 2009-09-01 Nuvasive, Inc. Surgical access system and related methods
US8137284B2 (en) * 2002-10-08 2012-03-20 Nuvasive, Inc. Surgical access system and related methods
AU2003214884A1 (en) 2003-01-15 2004-08-13 Nuvasive, Inc. Systems and methods for determining direction to a nerve
US7691057B2 (en) 2003-01-16 2010-04-06 Nuvasive, Inc. Surgical access system and related methods
US7819801B2 (en) * 2003-02-27 2010-10-26 Nuvasive, Inc. Surgical access system and related methods
US20040225228A1 (en) * 2003-05-08 2004-11-11 Ferree Bret A. Neurophysiological apparatus and procedures
US20040260358A1 (en) * 2003-06-17 2004-12-23 Robin Vaughan Triggered electromyographic test device and methods of use thereof
US8419728B2 (en) * 2003-06-30 2013-04-16 Depuy Products, Inc. Surgical scalpel and system particularly for use in a transverse carpal ligament surgical procedure
WO2005013805A2 (en) * 2003-08-05 2005-02-17 Nuvasive, Inc. Systemand methods for performing dynamic pedicle integrity assessments
US7905840B2 (en) 2003-10-17 2011-03-15 Nuvasive, Inc. Surgical access system and related methods
JP4463819B2 (en) 2003-09-25 2010-05-19 ヌヴァシヴ インコーポレイテッド Surgical access system
US8313430B1 (en) 2006-01-11 2012-11-20 Nuvasive, Inc. Surgical access system and related methods
US10342452B2 (en) * 2004-07-29 2019-07-09 Medtronic Xomed, Inc. Stimulator handpiece for an evoked potential monitoring system
US8538539B2 (en) 2004-10-07 2013-09-17 Nu Vasive, Inc. System and methods for assessing the neuromuscular pathway prior to nerve testing
WO2006042241A2 (en) 2004-10-08 2006-04-20 Nuvasive, Inc. Surgical access system and related methods
US7887538B2 (en) 2005-10-15 2011-02-15 Baxano, Inc. Methods and apparatus for tissue modification
US8257356B2 (en) 2004-10-15 2012-09-04 Baxano, Inc. Guidewire exchange systems to treat spinal stenosis
US20060095028A1 (en) 2004-10-15 2006-05-04 Baxano, Inc. Devices and methods for tissue access
AU2005295589B2 (en) 2004-10-15 2009-12-03 Baxano, Inc. Devices and methods for tissue removal
US8430881B2 (en) 2004-10-15 2013-04-30 Baxano, Inc. Mechanical tissue modification devices and methods
US7938830B2 (en) 2004-10-15 2011-05-10 Baxano, Inc. Powered tissue modification devices and methods
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