WO2003020107A3 - Soft and calcified tissue implants - Google Patents

Soft and calcified tissue implants Download PDF

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Publication number
WO2003020107A3
WO2003020107A3 PCT/US2002/027236 US0227236W WO03020107A3 WO 2003020107 A3 WO2003020107 A3 WO 2003020107A3 US 0227236 W US0227236 W US 0227236W WO 03020107 A3 WO03020107 A3 WO 03020107A3
Authority
WO
WIPO (PCT)
Prior art keywords
dermis
disclosed
soft
tissue implants
calcified tissue
Prior art date
Application number
PCT/US2002/027236
Other languages
French (fr)
Other versions
WO2003020107A2 (en
Inventor
Dayna Burskirk
Christopher Seid
John F Wironen
James M Gross
Gina Scurti
Original Assignee
Regeneration Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneration Tech Inc filed Critical Regeneration Tech Inc
Priority to CA002459050A priority Critical patent/CA2459050A1/en
Priority to AU2002323425A priority patent/AU2002323425B8/en
Priority to EP02757406A priority patent/EP1427322B1/en
Priority to DE60229539T priority patent/DE60229539D1/en
Priority to JP2003524426A priority patent/JP2005503850A/en
Publication of WO2003020107A2 publication Critical patent/WO2003020107A2/en
Publication of WO2003020107A3 publication Critical patent/WO2003020107A3/en

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    • A61B17/1662Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for particular parts of the body
    • A61B17/1671Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for particular parts of the body for the spine
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    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/0097Coating or prosthesis-covering structure made of pharmaceutical products, e.g. antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00976Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

Disclosed herein is processed dermis graft for use in orthopedic surgical procedures. Specifically exemplified herein is a processed dermis graft comprising one or more bone blocks having a groove cut into the surface thereof, wherein said groove is sufficient to accommodate a fixation screw. Also disclosed is a method of processing dermis that results in a dermis derived implant suitable to replace a tendon or ligament in a recipient in need thereof. Other compositions and applications of a dermis derived implant, and methods of manufacture and use, are disclosed.
PCT/US2002/027236 2001-08-29 2002-08-27 Soft and calcified tissue implants WO2003020107A2 (en)

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CA002459050A CA2459050A1 (en) 2001-08-29 2002-08-27 Soft and calcified tissue implants
AU2002323425A AU2002323425B8 (en) 2001-08-29 2002-08-27 Soft and calcified tissue implants
EP02757406A EP1427322B1 (en) 2001-08-29 2002-08-27 Soft and calcified tissue implants
DE60229539T DE60229539D1 (en) 2001-08-29 2002-08-27 SOFT AND CALCIFIED FABRIC IMPLANTS
JP2003524426A JP2005503850A (en) 2001-08-29 2002-08-27 Soft and calcified tissue implant

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US09/942,537 2001-08-29
US09/942,537 US6893462B2 (en) 2000-01-11 2001-08-29 Soft and calcified tissue implants

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WO2003020107A3 true WO2003020107A3 (en) 2003-12-04

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JP (2) JP2005503850A (en)
AU (1) AU2002323425B8 (en)
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877175B2 (en) 2006-09-14 2014-11-04 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9127084B2 (en) 2006-09-14 2015-09-08 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9155749B2 (en) 2006-09-14 2015-10-13 Medgenics Medical Israel Ltd. Long lasting drug formulations

Families Citing this family (217)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482584B1 (en) 1998-11-13 2002-11-19 Regeneration Technologies, Inc. Cyclic implant perfusion cleaning and passivation process
US20010031254A1 (en) * 1998-11-13 2001-10-18 Bianchi John R. Assembled implant
US6497726B1 (en) 2000-01-11 2002-12-24 Regeneration Technologies, Inc. Materials and methods for improved bone tendon bone transplantation
US6258124B1 (en) * 1999-05-10 2001-07-10 C. R. Bard, Inc. Prosthetic repair fabric
FR2897259B1 (en) 2006-02-15 2008-05-09 Ldr Medical Soc Par Actions Si INTERSOMATIC TRANSFORAMINAL CAGE WITH INTERBREBAL FUSION GRAFT AND CAGE IMPLANTATION INSTRUMENT
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6893462B2 (en) * 2000-01-11 2005-05-17 Regeneration Technologies, Inc. Soft and calcified tissue implants
US20030023304A1 (en) * 2000-01-11 2003-01-30 Carter Kevin C. Materials and methods for improved bone tendon bone transplantation
US20030097179A1 (en) * 2000-01-11 2003-05-22 Carter Kevin C. Materials and methods for improved bone tendon bone transplantation
WO2001078798A1 (en) * 2000-02-10 2001-10-25 Regeneration Technologies, Inc. Assembled implant
US20020119437A1 (en) * 2000-09-20 2002-08-29 Grooms Jamie M. Method of preparing and processing transplant tissue
US6752831B2 (en) * 2000-12-08 2004-06-22 Osteotech, Inc. Biocompatible osteogenic band for repair of spinal disorders
US6562073B2 (en) * 2001-02-06 2003-05-13 Sdgi Holding, Inc. Spinal bone implant
US7195642B2 (en) * 2001-03-13 2007-03-27 Mckernan Daniel J Method and apparatus for fixing a graft in a bone tunnel
GB0107708D0 (en) 2001-03-28 2001-05-16 Imp College Innovations Ltd Bone fixated,articulated joint load control device
FR2827156B1 (en) 2001-07-13 2003-11-14 Ldr Medical VERTEBRAL CAGE DEVICE WITH MODULAR FASTENING
US8512376B2 (en) 2002-08-30 2013-08-20 Arthrex, Inc. Method and apparatus for internal fixation of an acromioclavicular joint dislocation of the shoulder
JP2005505352A (en) * 2001-10-11 2005-02-24 シュトラウマン・ホールディング・アクチェンゲゼルシャフト Osteophilic implant
US8501396B2 (en) 2001-11-05 2013-08-06 Medgenics Medical Israel Ltd. Dermal micro-organs, methods and apparatuses for producing and using the same
US7468242B2 (en) 2001-11-05 2008-12-23 Medgenics, Inc. Dermal micro organs, methods and apparatuses for producing and using the same
US8088568B2 (en) 2001-11-05 2012-01-03 Medgentics, Inc. Dermal micro-organs, methods and apparatuses for producing and using the same
WO2003044037A2 (en) * 2001-11-21 2003-05-30 Yeda Research And Development Co Ltd. Process for the manufacture of human mononuclear phagocytic leukocytes
NZ537735A (en) * 2002-07-03 2006-08-31 Pericor Science Inc Compositions of hyaluronic acid and methods of use
US20040068262A1 (en) * 2002-10-02 2004-04-08 Mark Lemos Soft tissue fixation implant
US7682392B2 (en) * 2002-10-30 2010-03-23 Depuy Spine, Inc. Regenerative implants for stabilizing the spine and devices for attachment of said implants
GB0227161D0 (en) * 2002-11-21 2002-12-24 Xiros Plc Prosthetic implant assembly
US7449025B1 (en) 2002-12-17 2008-11-11 O'donnell Pat D Surgical instrument to secure body tissues
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
KR101134436B1 (en) 2003-05-01 2012-04-09 메드제닉스 인코포레이티드 Dermal micro organs, methods and apparatuses for producing and using the same
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20050203513A1 (en) * 2003-09-24 2005-09-15 Tae-Ahn Jahng Spinal stabilization device
US7815665B2 (en) * 2003-09-24 2010-10-19 N Spine, Inc. Adjustable spinal stabilization system
US7137985B2 (en) * 2003-09-24 2006-11-21 N Spine, Inc. Marking and guidance method and system for flexible fixation of a spine
US8979900B2 (en) 2003-09-24 2015-03-17 DePuy Synthes Products, LLC Spinal stabilization device
US7763052B2 (en) * 2003-12-05 2010-07-27 N Spine, Inc. Method and apparatus for flexible fixation of a spine
JPWO2005063314A1 (en) * 2003-12-26 2007-12-20 株式会社カルディオ Decellularized tissue and method for producing the same
CN101961270B (en) 2004-02-04 2016-08-10 Ldr医学公司 Intervertebral disk prosthesis
AU2005215772B2 (en) * 2004-02-13 2011-11-17 Frantz Medical Development, Ltd Soft tissue repair apparatus and method
US7407511B2 (en) * 2004-05-13 2008-08-05 Wright Medical Technology Inc Methods and materials for connective tissue repair
US7799081B2 (en) 2004-09-14 2010-09-21 Aeolin, Llc System and method for spinal fusion
US20060069436A1 (en) * 2004-09-30 2006-03-30 Depuy Spine, Inc. Trial disk implant
DE102004048938B4 (en) * 2004-10-07 2015-04-02 Synthes Gmbh Device for the dynamic stabilization of vertebral bodies
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US8088130B2 (en) 2006-02-03 2012-01-03 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8128658B2 (en) 2004-11-05 2012-03-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US9801708B2 (en) 2004-11-05 2017-10-31 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8137382B2 (en) 2004-11-05 2012-03-20 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US7749250B2 (en) 2006-02-03 2010-07-06 Biomet Sports Medicine, Llc Soft tissue repair assembly and associated method
US8840645B2 (en) 2004-11-05 2014-09-23 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8303604B2 (en) 2004-11-05 2012-11-06 Biomet Sports Medicine, Llc Soft tissue repair device and method
US7601165B2 (en) 2006-09-29 2009-10-13 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable suture loop
US7909851B2 (en) 2006-02-03 2011-03-22 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US7857830B2 (en) * 2006-02-03 2010-12-28 Biomet Sports Medicine, Llc Soft tissue repair and conduit device
US7905904B2 (en) 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US9017381B2 (en) 2007-04-10 2015-04-28 Biomet Sports Medicine, Llc Adjustable knotless loops
US8298262B2 (en) 2006-02-03 2012-10-30 Biomet Sports Medicine, Llc Method for tissue fixation
US8118836B2 (en) 2004-11-05 2012-02-21 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8361113B2 (en) 2006-02-03 2013-01-29 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8998949B2 (en) 2004-11-09 2015-04-07 Biomet Sports Medicine, Llc Soft tissue conduit device
US20060111786A1 (en) * 2004-11-22 2006-05-25 Orthopedic Development Corporation Metallic prosthetic implant for use in minimally invasive acromio-clavicular shoulder joint hemi-arthroplasty
US8021392B2 (en) * 2004-11-22 2011-09-20 Minsurg International, Inc. Methods and surgical kits for minimally-invasive facet joint fusion
US20060111779A1 (en) * 2004-11-22 2006-05-25 Orthopedic Development Corporation, A Florida Corporation Minimally invasive facet joint fusion
US20060111780A1 (en) * 2004-11-22 2006-05-25 Orthopedic Development Corporation Minimally invasive facet joint hemi-arthroplasty
US7901437B2 (en) 2007-01-26 2011-03-08 Jackson Roger P Dynamic stabilization member with molded connection
US7727278B2 (en) 2005-03-04 2010-06-01 Rti Biologics, Inc. Self fixing assembled bone-tendon-bone graft
US7776089B2 (en) 2005-03-04 2010-08-17 Rti Biologics, Inc. Assembled bone-tendon-bone grafts
US8470038B2 (en) 2005-03-04 2013-06-25 Rti Biologics, Inc. Adjustable and fixed assembled bone-tendon-bone graft
US7763071B2 (en) 2005-03-04 2010-07-27 Rti Biologics, Inc. Bone block assemblies and their use in assembled bone-tendon-bone grafts
US9788821B2 (en) * 2005-04-29 2017-10-17 Cook Biotech Incorporated Physically modified extracellular matrix materials and uses thereof
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US8128552B2 (en) * 2005-08-22 2012-03-06 O'donnell Pat D Surgical instrument for treating female pelvic prolapse
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
FR2891135B1 (en) 2005-09-23 2008-09-12 Ldr Medical Sarl INTERVERTEBRAL DISC PROSTHESIS
US20070123984A1 (en) * 2005-10-26 2007-05-31 Zimmer Technology, Inc. Ligament attachment and repair device
US20070123988A1 (en) * 2005-10-28 2007-05-31 Halkey-Roberts Corporation Tapered anchor for tendon graft
US20100040668A1 (en) * 2006-01-12 2010-02-18 Rutgers, The State University Of New Jersey Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof
US8287914B2 (en) 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
US11259792B2 (en) 2006-02-03 2022-03-01 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US9271713B2 (en) 2006-02-03 2016-03-01 Biomet Sports Medicine, Llc Method and apparatus for tensioning a suture
US9468433B2 (en) 2006-02-03 2016-10-18 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8771352B2 (en) 2011-05-17 2014-07-08 Biomet Sports Medicine, Llc Method and apparatus for tibial fixation of an ACL graft
US8251998B2 (en) 2006-08-16 2012-08-28 Biomet Sports Medicine, Llc Chondral defect repair
US8597327B2 (en) 2006-02-03 2013-12-03 Biomet Manufacturing, Llc Method and apparatus for sternal closure
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US11311287B2 (en) 2006-02-03 2022-04-26 Biomet Sports Medicine, Llc Method for tissue fixation
US8968364B2 (en) 2006-02-03 2015-03-03 Biomet Sports Medicine, Llc Method and apparatus for fixation of an ACL graft
US8562647B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for securing soft tissue to bone
US9078644B2 (en) 2006-09-29 2015-07-14 Biomet Sports Medicine, Llc Fracture fixation device
US9149267B2 (en) 2006-02-03 2015-10-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9538998B2 (en) 2006-02-03 2017-01-10 Biomet Sports Medicine, Llc Method and apparatus for fracture fixation
US8574235B2 (en) * 2006-02-03 2013-11-05 Biomet Sports Medicine, Llc Method for trochanteric reattachment
US8506597B2 (en) 2011-10-25 2013-08-13 Biomet Sports Medicine, Llc Method and apparatus for interosseous membrane reconstruction
US8652171B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US8652172B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Flexible anchors for tissue fixation
US10517587B2 (en) 2006-02-03 2019-12-31 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8801783B2 (en) 2006-09-29 2014-08-12 Biomet Sports Medicine, Llc Prosthetic ligament system for knee joint
US20070270854A1 (en) * 2006-03-30 2007-11-22 Zhigang Li Bone anchoring device
US8449576B2 (en) * 2006-06-28 2013-05-28 DePuy Synthes Products, LLC Dynamic fixation system
WO2008030668A2 (en) * 2006-07-26 2008-03-13 Lambert Systems, L.L.C. Biocompatible anchoring device for a soft tissue graft, method of making and method of using
US8672969B2 (en) 2006-09-29 2014-03-18 Biomet Sports Medicine, Llc Fracture fixation device
US8500818B2 (en) 2006-09-29 2013-08-06 Biomet Manufacturing, Llc Knee prosthesis assembly with ligament link
US11259794B2 (en) 2006-09-29 2022-03-01 Biomet Sports Medicine, Llc Method for implanting soft tissue
US9918826B2 (en) 2006-09-29 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
US20080195230A1 (en) * 2007-02-09 2008-08-14 Quijano Rodolfo C Pericardial tissue sheet
US20080260794A1 (en) * 2007-02-12 2008-10-23 Lauritzen Nels J Collagen products and methods for producing collagen products
US9056151B2 (en) * 2007-02-12 2015-06-16 Warsaw Orthopedic, Inc. Methods for collagen processing and products using processed collagen
US8007533B2 (en) * 2007-02-12 2011-08-30 Rti Biologics, Inc. Progressive grip assembled bone-tendon-bone grafts, methods of making, and methods of use
US20090105762A1 (en) * 2007-10-23 2009-04-23 Jackson Roger P Dynamic stabilization member with fin supported segment
WO2008103377A2 (en) * 2007-02-20 2008-08-28 Shriners Hospitals For Children In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US7766964B2 (en) * 2007-03-30 2010-08-03 Biomet Sports Medicine, Llc In situ graft preparation for knee ligament reconstruction
US7655041B2 (en) 2007-05-01 2010-02-02 Moximed, Inc. Extra-articular implantable mechanical energy absorbing systems and implantation method
US8894714B2 (en) 2007-05-01 2014-11-25 Moximed, Inc. Unlinked implantable knee unloading device
US8709090B2 (en) 2007-05-01 2014-04-29 Moximed, Inc. Adjustable absorber designs for implantable device
US8123805B2 (en) 2007-05-01 2012-02-28 Moximed, Inc. Adjustable absorber designs for implantable device
US20100137996A1 (en) * 2007-05-01 2010-06-03 Moximed, Inc. Femoral and tibial base components
US9907645B2 (en) * 2007-05-01 2018-03-06 Moximed, Inc. Adjustable absorber designs for implantable device
US8409281B2 (en) * 2007-05-01 2013-04-02 Moximed, Inc. Adjustable absorber designs for implantable device
US20080275567A1 (en) * 2007-05-01 2008-11-06 Exploramed Nc4, Inc. Extra-Articular Implantable Mechanical Energy Absorbing Systems
US9655648B2 (en) * 2007-05-01 2017-05-23 Moximed, Inc. Femoral and tibial base components
US20110245928A1 (en) 2010-04-06 2011-10-06 Moximed, Inc. Femoral and Tibial Bases
FR2916956B1 (en) 2007-06-08 2012-12-14 Ldr Medical INTERSOMATIC CAGE, INTERVERTEBRAL PROSTHESIS, ANCHORING DEVICE AND IMPLANTATION INSTRUMENTATION
US20090024225A1 (en) * 2007-07-16 2009-01-22 Stubbs James B Implant for Targeting Therapeutic Procedure
CN101801293A (en) * 2007-08-07 2010-08-11 新特斯有限责任公司 Dynamic cable system
WO2009036279A1 (en) 2007-09-14 2009-03-19 Purdue Research Foundation Demineralized cancellous bone scaffolds
JP5212933B2 (en) 2007-09-18 2013-06-19 国立大学法人 東京医科歯科大学 Method for manufacturing material for hard tissue contact device, and hard tissue contact device
JP5270925B2 (en) 2008-02-07 2013-08-21 雪印メグミルク株式会社 Microbial protective agent and method for producing frozen or freeze-dried microbial cells
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
JP2011525229A (en) * 2008-06-19 2011-09-15 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング Bone Screw Footrest Implants, Systems, and Technologies
CA2734560C (en) * 2008-06-20 2018-10-23 Cook Biotech Incorporated Composite extracellular matrix materials and medical products formed therefrom
US20100049258A1 (en) * 2008-08-19 2010-02-25 Dougherty Christopher P Single tunnel double bundle posterior cruciate ligament reconstruction
US8470036B2 (en) * 2008-09-30 2013-06-25 William S. Barnes Method and apparatus for reconstructing a ligament
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8333803B2 (en) * 2008-11-21 2012-12-18 Lifecell Corporation Reinforced biologic material
US8524253B2 (en) * 2008-11-25 2013-09-03 Warsaw Orthopedic, Inc. Bone regeneration device
US8992576B2 (en) * 2008-12-17 2015-03-31 DePuy Synthes Products, LLC Posterior spine dynamic stabilizer
US20100249929A1 (en) * 2009-03-24 2010-09-30 Joint Restoration Foundation Adjustable patella ligament for acl repair
US8439976B2 (en) * 2009-03-31 2013-05-14 Arthrex, Inc. Integrated adjustable button-suture-graft construct with two fixation devices
CA2757296C (en) 2009-03-31 2016-01-19 Medicinelodge, Inc. Double bundle acl repair
US8460379B2 (en) 2009-03-31 2013-06-11 Arthrex, Inc. Adjustable suture button construct and methods of tissue reconstruction
US8343227B2 (en) 2009-05-28 2013-01-01 Biomet Manufacturing Corp. Knee prosthesis assembly with ligament link
US9014787B2 (en) 2009-06-01 2015-04-21 Focal Therapeutics, Inc. Bioabsorbable target for diagnostic or therapeutic procedure
US9668771B2 (en) 2009-06-15 2017-06-06 Roger P Jackson Soft stabilization assemblies with off-set connector
US9278004B2 (en) 2009-08-27 2016-03-08 Cotera, Inc. Method and apparatus for altering biomechanics of the articular joints
US10349980B2 (en) 2009-08-27 2019-07-16 The Foundry, Llc Method and apparatus for altering biomechanics of the shoulder
US9795410B2 (en) 2009-08-27 2017-10-24 Cotera, Inc. Method and apparatus for force redistribution in articular joints
US9668868B2 (en) 2009-08-27 2017-06-06 Cotera, Inc. Apparatus and methods for treatment of patellofemoral conditions
US9861408B2 (en) 2009-08-27 2018-01-09 The Foundry, Llc Method and apparatus for treating canine cruciate ligament disease
EP2477579B1 (en) 2009-09-17 2015-12-23 LDR Holding Corporation Intervertebral implant having extendable bone fixation members
US8449612B2 (en) 2009-11-16 2013-05-28 Arthrocare Corporation Graft pulley and methods of use
BR112012016296A2 (en) 2009-12-31 2017-03-21 Ldr Medical anchorage device, intervertebral implant and implantation instrument
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
US20110184468A1 (en) * 2010-01-28 2011-07-28 Warsaw Orthopedic, Inc., An Indiana Corporation Spinous process fusion plate with osteointegration insert
US8834568B2 (en) 2010-02-04 2014-09-16 Paul S. Shapiro Surgical technique using a contoured allograft cartilage as a spacer of the carpo-metacarpal joint of the thumb or tarso-metatarsal joint of the toe
US8444699B2 (en) * 2010-02-18 2013-05-21 Biomet Manufacturing Corp. Method and apparatus for augmenting bone defects
US20110224720A1 (en) * 2010-03-11 2011-09-15 Cvdevices, Llc Devices, systems, and methods for closing a hole in cardiac tissue
US8460691B2 (en) 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
US8790699B2 (en) 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
EP2455001B1 (en) 2010-11-17 2020-07-22 Arthrex, Inc. Adjustable suture-button constructs for ligament reconstruction
EP2455040B1 (en) 2010-11-17 2015-03-04 Arthrex, Inc. Adjustable suture-button construct for knotless stabilization of cranial cruciate deficient ligament stifle
EP2455002B1 (en) 2010-11-17 2019-04-03 Arthrex, Inc. Adjustable suture-button construct for ankle syndesmosis repair
US20140205646A1 (en) 2011-02-14 2014-07-24 Mimedx Group, Inc. Tissue grafts modified with a cross-linking agent and method of making and using the same
US9044270B2 (en) 2011-03-29 2015-06-02 Moximed, Inc. Apparatus for controlling a load on a hip joint
US9694106B2 (en) 2011-07-11 2017-07-04 Mimedx Group, Inc. Synthetic collagen threads for cosmetic uses including skin wrinkle treatments and associated methods
US9301745B2 (en) 2011-07-21 2016-04-05 Arthrex, Inc. Knotless suture constructs
US9332979B2 (en) 2011-07-22 2016-05-10 Arthrex, Inc. Tensionable knotless acromioclavicular repairs and constructs
WO2013016571A1 (en) 2011-07-28 2013-01-31 Harbor Medtech, Inc. Crosslinked human or animal tissue products and their methods of manufacture and use
US9107653B2 (en) 2011-09-22 2015-08-18 Arthrex, Inc. Tensionable knotless anchors with splice and methods of tissue repair
US10245016B2 (en) 2011-10-12 2019-04-02 Arthrex, Inc. Adjustable self-locking loop constructs for tissue repairs and reconstructions
US8968402B2 (en) 2011-10-18 2015-03-03 Arthrocare Corporation ACL implants, instruments, and methods
US9357991B2 (en) 2011-11-03 2016-06-07 Biomet Sports Medicine, Llc Method and apparatus for stitching tendons
US9370350B2 (en) 2011-11-10 2016-06-21 Biomet Sports Medicine, Llc Apparatus for coupling soft tissue to a bone
US9381013B2 (en) 2011-11-10 2016-07-05 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9357992B2 (en) 2011-11-10 2016-06-07 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
WO2013086404A1 (en) 2011-12-09 2013-06-13 The Board Of Trustees Of The Leland Stanford Junior University Decellularized composite tissue bioscaffolds for musculoskeletal tissue interface reconstruction and methods of production
EP2601894B1 (en) 2011-12-09 2018-08-29 Arthrex, Inc. Tensionable knotless anchor systems
TWI448270B (en) * 2011-12-22 2014-08-11 Spine Asia Co Ltd A A compound grade intervertebral disc reduction device
JP6254094B2 (en) * 2011-12-22 2017-12-27 ミメディクス グループ インコーポレイテッド Cross-linked dehydrated placental tissue graft and methods of making and using the same
CA2861048C (en) * 2012-01-24 2021-01-12 Lifecell Corporation Elongated tissue matrices
FR2987256B1 (en) 2012-02-24 2014-08-08 Ldr Medical ANCHORING DEVICE FOR INTERVERTEBRAL IMPLANT, INTERVERTEBRAL IMPLANT AND IMPLANTATION INSTRUMENTATION
US20130289389A1 (en) 2012-04-26 2013-10-31 Focal Therapeutics Surgical implant for marking soft tissue
US9737292B2 (en) 2012-06-22 2017-08-22 Arthrex, Inc. Knotless suture anchors and methods of tissue repair
US11338063B2 (en) 2012-08-15 2022-05-24 Mimedx Group, Inc. Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
US9468466B1 (en) 2012-08-24 2016-10-18 Cotera, Inc. Method and apparatus for altering biomechanics of the spine
AU2014209124A1 (en) 2013-01-28 2015-09-17 Cartiva, Inc. Systems and methods for orthopedic repair
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
US9757119B2 (en) 2013-03-08 2017-09-12 Biomet Sports Medicine, Llc Visual aid for identifying suture limbs arthroscopically
US9918827B2 (en) 2013-03-14 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
US10029030B2 (en) 2013-03-15 2018-07-24 Mimedx Group, Inc. Molded placental tissue compositions and methods of making and using the same
US9345589B2 (en) * 2013-12-19 2016-05-24 Ilion Medical, Inc. Bone implants for orthopedic procedures and corresponding methods
US10136886B2 (en) 2013-12-20 2018-11-27 Biomet Sports Medicine, Llc Knotless soft tissue devices and techniques
WO2015109329A1 (en) 2014-01-17 2015-07-23 Mimedx Group, Inc. Method for inducing angiogenesis
US9615822B2 (en) 2014-05-30 2017-04-11 Biomet Sports Medicine, Llc Insertion tools and method for soft anchor
US9700291B2 (en) 2014-06-03 2017-07-11 Biomet Sports Medicine, Llc Capsule retractor
AU2015292332A1 (en) 2014-07-25 2017-02-16 Focal Therapeutics, Inc. Implantable devices and techniques for oncoplastic surgery
US10039543B2 (en) 2014-08-22 2018-08-07 Biomet Sports Medicine, Llc Non-sliding soft anchor
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US9955980B2 (en) 2015-02-24 2018-05-01 Biomet Sports Medicine, Llc Anatomic soft tissue repair
US9974534B2 (en) 2015-03-31 2018-05-22 Biomet Sports Medicine, Llc Suture anchor with soft anchor of electrospun fibers
CN110755176B (en) * 2015-05-28 2022-07-08 4科技有限公司 Apparatus for delivery within a deployment tool in a constrained state
ITUB20152560A1 (en) * 2015-07-28 2017-01-28 Tt Tooth Transf S R L SYSTEM FOR PROCESSING TEETH IN BONE MATERIAL
US10335136B2 (en) 2015-08-20 2019-07-02 Arthrex, Inc. Tensionable constructs with multi-limb locking mechanism through single splice and methods of tissue repair
US10265060B2 (en) 2015-08-20 2019-04-23 Arthrex, Inc. Tensionable constructs with multi-limb locking mechanism through single splice and methods of tissue repair
US10470872B1 (en) * 2016-04-07 2019-11-12 Michael A. Scarpone Implantable articles for attaching tendons and/or ligaments to bone and/or cartilage, assemblies thereof, and methods of use thereof
US10707531B1 (en) 2016-09-27 2020-07-07 New Dominion Enterprises Inc. All-inorganic solvents for electrolytes
US11219502B2 (en) 2017-09-11 2022-01-11 Medtronic Advanced Energy, Llc Transformative shape-memory polymer tissue cavity marker devices, systems and deployment methods
US11324567B2 (en) 2018-02-01 2022-05-10 Medtronic Advanced Energy, Llc Expandable tissue cavity marker devices, systems and deployment methods
KR102150326B1 (en) * 2018-07-04 2020-09-01 (주)서한케어 Method for surface treatment of biocompatible affinity metal material
US11583609B2 (en) 2018-08-08 2023-02-21 Mimedx Group, Inc. Collagen constructs and methods of making the same
WO2023141208A1 (en) * 2022-01-19 2023-07-27 Restoration Biologics Llc Tissue graft and processing methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171326A (en) * 1989-02-06 1992-12-15 Trustees Of The University Of Pennsylvania Calcium phosphate ceramics for bone tissue calcification enhancement
US6190412B1 (en) * 1997-04-22 2001-02-20 Washington Research Foundation Trap-coated bone grafts and prostheses

Family Cites Families (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4744793A (en) * 1985-09-06 1988-05-17 Zimmer, Inc. Prosthetic ligament connection assembly
FI80605C (en) * 1986-11-03 1990-07-10 Biocon Oy Bone surgical biocomposite material
US4828562A (en) * 1988-02-04 1989-05-09 Pfizer Hospital Products Group, Inc. Anterior cruciate ligament prosthesis
US4950296A (en) * 1988-04-07 1990-08-21 Mcintyre Jonathan L Bone grafting units
DE3835237C1 (en) * 1988-10-15 1989-12-28 B. Braun Melsungen Ag, 3508 Melsungen, De
US5067962A (en) * 1989-04-18 1991-11-26 Baxter International Inc. Bioprosthetic ligament
US4927421A (en) * 1989-05-15 1990-05-22 Marlowe Goble E Process of endosteal fixation of a ligament
US5139520A (en) * 1990-01-31 1992-08-18 American Cyanamid Company Method for acl reconstruction
US5062843A (en) * 1990-02-07 1991-11-05 Mahony Iii Thomas H Interference fixation screw with integral instrumentation
DE69127977T2 (en) * 1990-09-04 1998-09-17 Smith & Nephew Inc N D Ges D S SURGICAL SCREW
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5320115A (en) * 1991-01-16 1994-06-14 Applied Biological Concepts Method and apparatus for arthroscopic knee surgery
US5116337A (en) * 1991-06-27 1992-05-26 Johnson Lanny L Fixation screw and method for ligament reconstruction
US5366457A (en) * 1991-12-13 1994-11-22 David A. McGuire Method and apparatus for preparing a bone and tendon graft
US5391169A (en) * 1991-12-13 1995-02-21 Mcguire; David A. Patellar tendon harvester
US5562669A (en) * 1994-01-13 1996-10-08 Mcguire; David A. Cruciate ligament reconstruction with tibial drill guide
US5234430A (en) * 1991-12-18 1993-08-10 Huebner Randall J Orthopedic fixation screw and method
US5425773A (en) * 1992-01-06 1995-06-20 Danek Medical, Inc. Intervertebral disk arthroplasty device
US5425733A (en) 1992-02-19 1995-06-20 Arthrex, Inc. Interference screw with rounded back end and cannulated sheath for endosteal fixation of ligaments
US5733289A (en) * 1992-10-27 1998-03-31 Neoligaments Limited Ligament graft harvesting
EP0596829B1 (en) * 1992-11-02 2000-11-22 Sulzer Orthopädie AG Anchor for synthetic ligament
US5443509A (en) * 1992-12-10 1995-08-22 Linvatec Corporation Interference bone-fixation screw with multiple interleaved threads
US5397356A (en) 1993-01-15 1995-03-14 Depuy Inc. Pin for securing a replacement ligament to a bone
US5397357A (en) * 1993-02-18 1995-03-14 Arthrex, Inc. Method for preparing a bone-tendon-bone core graft
US5632748A (en) * 1993-06-14 1997-05-27 Linvatec Corporation Endosteal anchoring device for urging a ligament against a bone surface
US5454811A (en) * 1993-11-08 1995-10-03 Smith & Nephew Dyonics, Inc. Cam lock orthopedic fixation screw and method
US5769899A (en) * 1994-08-12 1998-06-23 Matrix Biotechnologies, Inc. Cartilage repair unit
US5645589A (en) * 1994-08-22 1997-07-08 Li Medical Technologies, Inc. Anchor and method for securement into a bore
AU713540B2 (en) * 1994-10-25 1999-12-02 Osteonics Corp. Interlocking structural elements and method for bone repair, augmentation and replacement
US6106556A (en) * 1994-12-02 2000-08-22 Omeros Medical Systems, Inc. Tendon and ligament repair system
US5728118A (en) * 1995-03-29 1998-03-17 Linvatec Corporation Apparatus and method for harvesting a bone-tendon-bone ligament graft
US6231608B1 (en) * 1995-06-07 2001-05-15 Crosscart, Inc. Aldehyde and glycosidase-treated soft and bone tissue xenografts
US5814084A (en) * 1996-01-16 1998-09-29 University Of Florida Tissue Bank, Inc. Diaphysial cortical dowel
US5681314A (en) * 1996-06-21 1997-10-28 Lawrence M. Shall Cutting a bone graft
US5782832A (en) * 1996-10-01 1998-07-21 Surgical Dynamics, Inc. Spinal fusion implant and method of insertion thereof
US5772664A (en) * 1997-02-12 1998-06-30 Wright Medical Technology, Inc. Instrument for harvesting bone grafts having substantially cylindrical bone plugs
US6206917B1 (en) * 1997-05-02 2001-03-27 St. Jude Medical, Inc. Differential treatment of prosthetic devices
US6613278B1 (en) 1998-11-13 2003-09-02 Regeneration Technologies, Inc. Tissue pooling process
WO1999009914A1 (en) 1997-08-27 1999-03-04 University Of Florida Tissue Bank, Inc. Cortical bone cervical smith-robinson fusion implant
US5891146A (en) * 1997-10-15 1999-04-06 Applied Biological Concepts, Inc. Wedge orthopedic screw
US6090998A (en) * 1997-10-27 2000-07-18 University Of Florida Segmentally demineralized bone implant
US6146420A (en) * 1997-12-10 2000-11-14 Sdgi Holdings, Inc. Osteogenic fusion device
US5899939A (en) * 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US20020076429A1 (en) * 1998-01-28 2002-06-20 John F. Wironen Bone paste subjected to irradiative and thermal treatment
ES2172986T3 (en) * 1998-03-23 2002-10-01 Bio Vascular Inc IMPLANTS AND PREPARATION PROCESS.
US6019792A (en) * 1998-04-23 2000-02-01 Cauthen Research Group, Inc. Articulating spinal implant
JP2002512079A (en) * 1998-04-23 2002-04-23 コーゼン リサーチ グループ インク. Articulated spinal implant
JPH11345175A (en) * 1998-06-02 1999-12-14 Nec Kofu Ltd System and method for controlling substitutive path
DE69916280T2 (en) * 1998-08-03 2005-05-25 Synthes Ag Chur, Chur INTERVERTEBRAL allograft DISTANZSTÜCK
US6355066B1 (en) * 1998-08-19 2002-03-12 Andrew C. Kim Anterior cruciate ligament reconstruction hamstring tendon fixation system
US6497726B1 (en) * 2000-01-11 2002-12-24 Regeneration Technologies, Inc. Materials and methods for improved bone tendon bone transplantation
US6025538A (en) * 1998-11-20 2000-02-15 Musculoskeletal Transplant Foundation Compound bone structure fabricated from allograft tissue
US20020165611A1 (en) * 1998-12-22 2002-11-07 Robert-Jan Enzerink Graft material convenience package
US6200347B1 (en) 1999-01-05 2001-03-13 Lifenet Composite bone graft, method of making and using same
WO2000054821A1 (en) 1999-03-16 2000-09-21 Regeneration Technologies, Inc. Molded implants for orthopedic applications
IT1310423B1 (en) * 1999-07-29 2002-02-13 Giovanni Zaccherotti MEANS OF FEMORAL FIXATION OF SEMITENDINOUS AND DELGRAGILE TENDONS FOR RECONSTRUCTION OF THE ANTERIOR CROSS LIGAMENT.
US6494883B1 (en) * 2000-05-26 2002-12-17 Bret A. Ferree Bone reinforcers
US6737053B1 (en) * 1999-11-12 2004-05-18 National University Of Singapore Tissue-engineered ligament
US20030097179A1 (en) * 2000-01-11 2003-05-22 Carter Kevin C. Materials and methods for improved bone tendon bone transplantation
US6893462B2 (en) * 2000-01-11 2005-05-17 Regeneration Technologies, Inc. Soft and calcified tissue implants
DE60122885T2 (en) * 2000-06-14 2007-05-16 Teppo Järvinen FIXING ANCHOR
US6517579B1 (en) * 2000-09-06 2003-02-11 Lonnie E. Paulos Method and apparatus for securing a soft tissue graft to bone during an ACL reconstruction
US6579295B1 (en) * 2000-09-25 2003-06-17 Robert S. Supinski Tendon anchors
DE60129850T2 (en) * 2000-11-24 2008-04-30 UNIVERSITé LAVAL REPLACEMENT FOR COMPOUND WOVENS, METHOD FOR THE PRODUCTION AND USE THEREOF
EP1359951A2 (en) * 2001-01-25 2003-11-12 Regeneration Technologies, Inc. Injectable porous bone graft materials
US7195642B2 (en) * 2001-03-13 2007-03-27 Mckernan Daniel J Method and apparatus for fixing a graft in a bone tunnel
GB0116605D0 (en) * 2001-07-07 2001-08-29 Atlantech Medical Devices Ltd Expandable bone anchor
US6887271B2 (en) * 2001-09-28 2005-05-03 Ethicon, Inc. Expanding ligament graft fixation system and method
US20030078659A1 (en) * 2001-10-23 2003-04-24 Jun Yang Graft element
EP1334702B1 (en) * 2002-02-08 2004-07-07 Karl Storz GmbH & Co. KG Anchor element to anchor a ligament transplant
US6730124B2 (en) * 2002-03-08 2004-05-04 Musculoskeletal Transplant Foundation Bone-tendon-bone assembly with cancellous allograft bone block
US6890354B2 (en) * 2002-03-08 2005-05-10 Musculoskeletal Transplant Foundation Bone-tendon-bone assembly with allograft bone block and method for inserting same
US20030212456A1 (en) * 2002-05-09 2003-11-13 John Lipchitz Implant for tissue repair
US7357803B2 (en) * 2002-11-05 2008-04-15 Linvatec Corporation Rotating ring ligament fixation
DE102004025332A1 (en) * 2003-05-26 2004-12-16 Huber, Jakob, Dipl.-Ing. Alloplastic ligament, in particular, in the form of a crucial ligament consist of a plastic material which is at least partially coated with an aluminum oxide ceramic, a zirconium oxide ceramic or tantalum
US8226715B2 (en) * 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US7648676B2 (en) * 2004-04-20 2010-01-19 Rti Biologics, Inc. Process and apparatus for treating implants comprising soft tissue
US20060067971A1 (en) * 2004-09-27 2006-03-30 Story Brooks J Bone void filler
US7727278B2 (en) * 2005-03-04 2010-06-01 Rti Biologics, Inc. Self fixing assembled bone-tendon-bone graft
EP1832246B1 (en) * 2006-03-08 2019-06-12 Arthrex, Inc. Bundle graft and method of making same
US8298284B2 (en) * 2006-03-21 2012-10-30 Arthrex, Inc. Whip stitched graft construct and method of making the same
US8007533B2 (en) * 2007-02-12 2011-08-30 Rti Biologics, Inc. Progressive grip assembled bone-tendon-bone grafts, methods of making, and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171326A (en) * 1989-02-06 1992-12-15 Trustees Of The University Of Pennsylvania Calcium phosphate ceramics for bone tissue calcification enhancement
US6190412B1 (en) * 1997-04-22 2001-02-20 Washington Research Foundation Trap-coated bone grafts and prostheses

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8877175B2 (en) 2006-09-14 2014-11-04 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9127084B2 (en) 2006-09-14 2015-09-08 Medgenics Medical Israel Ltd. Long lasting drug formulations
US9155749B2 (en) 2006-09-14 2015-10-13 Medgenics Medical Israel Ltd. Long lasting drug formulations

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