WO2003015839A3 - Devices for intrabody delivery of molecules and systems and methods utilizing same - Google Patents

Devices for intrabody delivery of molecules and systems and methods utilizing same Download PDF

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Publication number
WO2003015839A3
WO2003015839A3 PCT/IL2002/000645 IL0200645W WO03015839A3 WO 2003015839 A3 WO2003015839 A3 WO 2003015839A3 IL 0200645 W IL0200645 W IL 0200645W WO 03015839 A3 WO03015839 A3 WO 03015839A3
Authority
WO
WIPO (PCT)
Prior art keywords
molecules
systems
devices
methods utilizing
utilizing same
Prior art date
Application number
PCT/IL2002/000645
Other languages
French (fr)
Other versions
WO2003015839A2 (en
Inventor
Eyal Doron
Avraham Penner
Original Assignee
Remon Medical Technologies Ltd
Eyal Doron
Avraham Penner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Remon Medical Technologies Ltd, Eyal Doron, Avraham Penner filed Critical Remon Medical Technologies Ltd
Priority to AU2002324312A priority Critical patent/AU2002324312A1/en
Publication of WO2003015839A2 publication Critical patent/WO2003015839A2/en
Publication of WO2003015839A3 publication Critical patent/WO2003015839A3/en

Links

Classifications

    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N—ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N30/00—Piezoelectric or electrostrictive devices
    • H10N30/80—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Abstract

A device (10) for controlled release of molecules is provided. The device (10) including: (a) a device body (12) having at least one reservoir (14) therein for containing the molecules, the at least one reservoir (14) being formed with a barrier (16) impermeable to the molecules thereby preventing release thereof from the at least one reservoir (14); and (b) at least one acoustic transducer (20) being attached to, or forming a part of, the device body (12), the at least one acoustic transducer (20) being for converting an acoustic signal (57) received thereby into an electrical signal, the electrical signal leading to barrier permeabilization and therefore release of the molecules from the at least one reservoir (14).
PCT/IL2002/000645 2001-08-16 2002-08-06 Devices for intrabody delivery of molecules and systems and methods utilizing same WO2003015839A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002324312A AU2002324312A1 (en) 2001-08-16 2002-08-06 Devices for intrabody delivery of molecules and systems and methods utilizing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/930,455 2001-08-16
US09/930,455 US20030036746A1 (en) 2001-08-16 2001-08-16 Devices for intrabody delivery of molecules and systems and methods utilizing same

Publications (2)

Publication Number Publication Date
WO2003015839A2 WO2003015839A2 (en) 2003-02-27
WO2003015839A3 true WO2003015839A3 (en) 2004-03-18

Family

ID=25459350

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2002/000645 WO2003015839A2 (en) 2001-08-16 2002-08-06 Devices for intrabody delivery of molecules and systems and methods utilizing same

Country Status (3)

Country Link
US (5) US20030036746A1 (en)
AU (1) AU2002324312A1 (en)
WO (1) WO2003015839A2 (en)

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US20120327747A1 (en) 2012-12-27
US8277441B2 (en) 2012-10-02
US8647328B2 (en) 2014-02-11
US20040032187A1 (en) 2004-02-19
US20110178578A1 (en) 2011-07-21
US7948148B2 (en) 2011-05-24
WO2003015839A2 (en) 2003-02-27
US20030036746A1 (en) 2003-02-20
US20080191581A9 (en) 2008-08-14
US7621905B2 (en) 2009-11-24

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