WO2003007782A3 - Biodegradable injectable implants and related methods of manufacture and use - Google Patents

Biodegradable injectable implants and related methods of manufacture and use Download PDF

Info

Publication number
WO2003007782A3
WO2003007782A3 PCT/US2002/020802 US0220802W WO03007782A3 WO 2003007782 A3 WO2003007782 A3 WO 2003007782A3 US 0220802 W US0220802 W US 0220802W WO 03007782 A3 WO03007782 A3 WO 03007782A3
Authority
WO
WIPO (PCT)
Prior art keywords
manufacture
implants
related methods
injectable implants
injectable
Prior art date
Application number
PCT/US2002/020802
Other languages
French (fr)
Other versions
WO2003007782A2 (en
Inventor
Crisofo Peralta Caseres
Lagarde Danel Leon D
Original Assignee
Medgraft Microtech Inc
Crisofo Peralta Caseres
Lagarde Danel Leon D
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IL15962402A priority Critical patent/IL159624A0/en
Priority to ES02742366T priority patent/ES2385030T3/en
Priority to CA2452412A priority patent/CA2452412C/en
Priority to KR1020037017180A priority patent/KR100954741B1/en
Application filed by Medgraft Microtech Inc, Crisofo Peralta Caseres, Lagarde Danel Leon D filed Critical Medgraft Microtech Inc
Priority to BR0210722-8A priority patent/BR0210722A/en
Priority to JP2003513396A priority patent/JP4490095B2/en
Priority to MXPA04000156A priority patent/MXPA04000156A/en
Priority to BRPI0210722A priority patent/BRPI0210722B8/en
Priority to EP02742366A priority patent/EP1411861B1/en
Priority to AT02742366T priority patent/ATE552017T1/en
Priority to AU2002315505A priority patent/AU2002315505B2/en
Publication of WO2003007782A2 publication Critical patent/WO2003007782A2/en
Publication of WO2003007782A3 publication Critical patent/WO2003007782A3/en
Priority to IL159624A priority patent/IL159624A/en
Priority to HK05102438A priority patent/HK1069099A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions

Abstract

This invention is directed to the field of medical implants, and more specifically to biodegradable injectable implants and their methods of manufacture and use. The injectable implants disclosed herein comprise glycolic acid and bio-compatible/bio-absorbable polymeric particles containing a polymer of lactic acid. The particles are small enough to be injected through a needle but large enough to avoid engulfment by macrophages. The injectables of this invention may be in a pre-activated solid form or an activated form (e.g., injectable suspension or emulsion).
PCT/US2002/020802 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use WO2003007782A2 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP2003513396A JP4490095B2 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use
CA2452412A CA2452412C (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use
KR1020037017180A KR100954741B1 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use
BRPI0210722A BRPI0210722B8 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of production and use
BR0210722-8A BR0210722A (en) 2001-06-29 2002-06-28 Biodegradable Injectable Implants and Related Methods of Production and Use
ES02742366T ES2385030T3 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and procedures related to their manufacture and use
MXPA04000156A MXPA04000156A (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use.
IL15962402A IL159624A0 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use
EP02742366A EP1411861B1 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use
AT02742366T ATE552017T1 (en) 2001-06-29 2002-06-28 BIODEGRADABLE INJECTABLE IMPLANTS AND RELATED METHODS OF MANUFACTURING AND USE
AU2002315505A AU2002315505B2 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use
IL159624A IL159624A (en) 2001-06-29 2003-12-29 Biodegradable injectable implants and related methods of manufacture and use
HK05102438A HK1069099A1 (en) 2001-06-29 2005-03-22 Biodegradable injectabel implants and related methods of manufacture and use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
MXPA/A2001/006732 2001-06-29
MXPA01006732 2001-06-29
US228301A 2001-12-05 2001-12-05
US10/002,283 2001-12-05

Publications (2)

Publication Number Publication Date
WO2003007782A2 WO2003007782A2 (en) 2003-01-30
WO2003007782A3 true WO2003007782A3 (en) 2003-04-24

Family

ID=32301934

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/020802 WO2003007782A2 (en) 2001-06-29 2002-06-28 Biodegradable injectable implants and related methods of manufacture and use

Country Status (15)

Country Link
US (2) US7314636B2 (en)
EP (1) EP1411861B1 (en)
JP (1) JP4490095B2 (en)
KR (1) KR100954741B1 (en)
CN (1) CN100339057C (en)
AT (1) ATE552017T1 (en)
AU (1) AU2002315505B2 (en)
BR (2) BR0210722A (en)
CA (1) CA2452412C (en)
CO (1) CO5540289A2 (en)
ES (1) ES2385030T3 (en)
HK (1) HK1069099A1 (en)
IL (2) IL159624A0 (en)
MX (1) MXPA04000156A (en)
WO (1) WO2003007782A2 (en)

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