WO2003005887A3 - System and methods for determining nerve proximity, direction, and pathology during surgery - Google Patents

System and methods for determining nerve proximity, direction, and pathology during surgery Download PDF

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Publication number
WO2003005887A3
WO2003005887A3 PCT/US2002/022247 US0222247W WO03005887A3 WO 2003005887 A3 WO2003005887 A3 WO 2003005887A3 US 0222247 W US0222247 W US 0222247W WO 03005887 A3 WO03005887 A3 WO 03005887A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
during surgery
nerve proximity
determining nerve
pathology during
Prior art date
Application number
PCT/US2002/022247
Other languages
French (fr)
Other versions
WO2003005887A2 (en
Inventor
James E Gharib
Norbert Kaula
Jeffrey Blewett
Original Assignee
Nuvasive Inc
James E Gharib
Norbert Kaula
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23179048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2003005887(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to JP2003511700A priority Critical patent/JP4295086B2/en
Priority to EP02756464.0A priority patent/EP1417000B1/en
Application filed by Nuvasive Inc, James E Gharib, Norbert Kaula filed Critical Nuvasive Inc
Publication of WO2003005887A2 publication Critical patent/WO2003005887A2/en
Publication of WO2003005887A3 publication Critical patent/WO2003005887A3/en
Priority to US10/754,899 priority patent/US8068912B2/en
Priority to US11/652,705 priority patent/US9259144B2/en
Priority to US12/434,303 priority patent/US8050769B2/en
Priority to US12/711,937 priority patent/US7920922B2/en
Priority to US13/080,493 priority patent/US8055349B2/en
Priority to US13/292,065 priority patent/US8634904B2/en
Priority to US13/465,666 priority patent/US8812116B2/en
Priority to US13/466,398 priority patent/US8672840B2/en
Priority to US13/767,355 priority patent/US9037250B2/en
Priority to US14/687,745 priority patent/US9456783B2/en
Priority to US15/258,434 priority patent/US9931077B2/en
Priority to US15/944,780 priority patent/US10716509B2/en
Priority to US16/897,093 priority patent/US20200297277A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4887—Locating particular structures in or on the body
    • A61B5/4893—Nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00039—Electric or electromagnetic phenomena other than conductivity, e.g. capacity, inductivity, Hall effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1104—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs
    • A61B5/1106—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb induced by stimuli or drugs to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7217—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
    • A61B5/743—Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36017—External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin

Abstract

The present invention involves systems (10) and methods for determining nerve proximity, nerve direction, and pathology relative to a surgical instrument based on an identified relationship between neuromuscular responses and the stimulation signal that caused the neuromuscular responses.
PCT/US2002/022247 2001-07-11 2002-07-11 System and methods for determining nerve proximity, direction, and pathology during surgery WO2003005887A2 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
JP2003511700A JP4295086B2 (en) 2001-07-11 2002-07-11 System and method for determining nerve proximity, nerve orientation, and pathology during surgery
EP02756464.0A EP1417000B1 (en) 2001-07-11 2002-07-11 System for determining nerve proximity during surgery
US10/754,899 US8068912B2 (en) 2001-07-11 2004-01-09 System and methods for determining nerve proximity, direction, and pathology during surgery
US11/652,705 US9259144B2 (en) 2002-07-11 2007-01-12 Surgical access system and related methods
US12/434,303 US8050769B2 (en) 2001-07-11 2009-05-01 System and methods for determining nerve proximity, direction, and pathology during surgery
US12/711,937 US7920922B2 (en) 2001-07-11 2010-02-24 System and methods for determining nerve proximity, direction, and pathology during surgery
US13/080,493 US8055349B2 (en) 2001-07-11 2011-04-05 System and methods for determining nerve proximity, direction, and pathology during surgery
US13/292,065 US8634904B2 (en) 2001-07-11 2011-11-08 System and methods for determining nerve proximity, direction, and pathology during surgery
US13/465,666 US8812116B2 (en) 2001-07-11 2012-05-07 System and methods for determining nerve proximity, direction, and pathology during surgery
US13/466,398 US8672840B2 (en) 2002-06-26 2012-05-08 Surgical access system and related methods
US13/767,355 US9037250B2 (en) 2001-07-11 2013-02-14 System and methods for determining nerve proximity, direction and pathology during surgery
US14/687,745 US9456783B2 (en) 2001-07-11 2015-04-15 System and methods for determining nerve proximity, direction and pathology during surgery
US15/258,434 US9931077B2 (en) 2001-07-11 2016-09-07 System and methods for determining nerve proximity, direction and pathology during surgery
US15/944,780 US10716509B2 (en) 2001-07-11 2018-04-03 System and methods for determining nerve proximity, direction and pathology during surgery
US16/897,093 US20200297277A1 (en) 2001-07-11 2020-06-09 System and methods for determining nerve proximity, direction, and pathology during surgery

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30504101P 2001-07-11 2001-07-11
US06/305,041 2001-07-11

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/754,899 Continuation US8068912B2 (en) 2001-07-11 2004-01-09 System and methods for determining nerve proximity, direction, and pathology during surgery

Publications (2)

Publication Number Publication Date
WO2003005887A2 WO2003005887A2 (en) 2003-01-23
WO2003005887A3 true WO2003005887A3 (en) 2003-08-21

Family

ID=23179048

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/022247 WO2003005887A2 (en) 2001-07-11 2002-07-11 System and methods for determining nerve proximity, direction, and pathology during surgery

Country Status (5)

Country Link
US (11) US8068912B2 (en)
EP (1) EP1417000B1 (en)
JP (1) JP4295086B2 (en)
AU (1) AU2011202118B2 (en)
WO (1) WO2003005887A2 (en)

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US8915846B2 (en) 2002-06-26 2014-12-23 Nuvasive, Inc. Surgical access system and related methods
US8920500B1 (en) 2009-04-16 2014-12-30 Nuvasive, Inc. Methods and apparatus for performing spine surgery
US8942801B2 (en) 2003-09-25 2015-01-27 Nuvasive, Inc. Surgical access system and related methods
US8956283B2 (en) 2002-10-08 2015-02-17 Nuvasive, Inc. Surgical access system and related methods
US9014776B2 (en) 1998-12-23 2015-04-21 Nuvasive, Inc. Surgical access and nerve surveillance
US9037250B2 (en) 2001-07-11 2015-05-19 Nuvasive, Inc. System and methods for determining nerve proximity, direction and pathology during surgery
US9132021B2 (en) 2011-10-07 2015-09-15 Pioneer Surgical Technology, Inc. Intervertebral implant
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US9198765B1 (en) 2011-10-31 2015-12-01 Nuvasive, Inc. Expandable spinal fusion implants and related methods
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US9931077B2 (en) 2018-04-03
US7920922B2 (en) 2011-04-05
US20160374613A1 (en) 2016-12-29
US8812116B2 (en) 2014-08-19
US20100152604A1 (en) 2010-06-17
US20200297277A1 (en) 2020-09-24
EP1417000A4 (en) 2009-06-03
US20090209879A1 (en) 2009-08-20
US8055349B2 (en) 2011-11-08
US20130165814A1 (en) 2013-06-27
US8068912B2 (en) 2011-11-29
US20050182454A1 (en) 2005-08-18
US8050769B2 (en) 2011-11-01
US10716509B2 (en) 2020-07-21
US20110184308A1 (en) 2011-07-28
JP4295086B2 (en) 2009-07-15
US20150216478A1 (en) 2015-08-06
US20120220891A1 (en) 2012-08-30
JP2005516638A (en) 2005-06-09
US20180360378A1 (en) 2018-12-20
US9037250B2 (en) 2015-05-19
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EP1417000A2 (en) 2004-05-12
US8634904B2 (en) 2014-01-21

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