WO2003002173A1 - Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications - Google Patents
Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications Download PDFInfo
- Publication number
- WO2003002173A1 WO2003002173A1 PCT/US2002/015050 US0215050W WO03002173A1 WO 2003002173 A1 WO2003002173 A1 WO 2003002173A1 US 0215050 W US0215050 W US 0215050W WO 03002173 A1 WO03002173 A1 WO 03002173A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- plasma
- patient
- bioreactor
- cells
- blood
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
- A61M1/3489—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents by biological cells, e.g. bioreactor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1678—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes intracorporal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0415—Plasma
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002446580A CA2446580A1 (en) | 2001-05-14 | 2002-05-10 | Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications |
JP2003508411A JP2004531349A (en) | 2001-05-14 | 2002-05-10 | Process and apparatus utilizing INVIVO extracted plasma in tissue engineering devices, bioreactors, artificial organs, and cell therapy applications |
IL15850702A IL158507A0 (en) | 2001-05-14 | 2002-05-10 | Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications |
EP02780945A EP1387706A1 (en) | 2001-05-14 | 2002-05-10 | Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/858,029 | 2001-05-14 | ||
US09/858,029 US6607501B2 (en) | 2001-05-14 | 2001-05-14 | Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003002173A1 true WO2003002173A1 (en) | 2003-01-09 |
Family
ID=25327284
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/015050 WO2003002173A1 (en) | 2001-05-14 | 2002-05-10 | Process and apparatus for utilization of in vivo extracted plasma with tissue engineering devices, bioreactors, artificial organs, and cell therapy applications |
Country Status (6)
Country | Link |
---|---|
US (1) | US6607501B2 (en) |
EP (1) | EP1387706A1 (en) |
JP (1) | JP2004531349A (en) |
CA (1) | CA2446580A1 (en) |
IL (1) | IL158507A0 (en) |
WO (1) | WO2003002173A1 (en) |
Cited By (2)
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JP2007500511A (en) * | 2003-05-19 | 2007-01-18 | プロバイオゲン アーゲー | Artificial immune organ |
CN101102728B (en) * | 2005-01-10 | 2011-06-22 | 曲利姆医疗股份有限公司 | Stand with self-deployable portion |
Families Citing this family (37)
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US6620382B1 (en) | 1998-05-22 | 2003-09-16 | Biopheresis Technologies, Llc. | Method and compositions for treatment of cancers |
US8197430B1 (en) | 1998-05-22 | 2012-06-12 | Biopheresis Technologies, Inc. | Method and system to remove cytokine inhibitor in patients |
US6379708B1 (en) * | 1999-11-20 | 2002-04-30 | Cytologic, Llc | Method for enhancing immune responses in mammals |
US7144496B2 (en) * | 2000-11-02 | 2006-12-05 | Pall Corporation | Biological fluid analysis device |
US7481936B2 (en) * | 2001-10-17 | 2009-01-27 | Transvivo Inc. | Method and apparatus for patient fluid management |
US6849183B2 (en) * | 2002-08-13 | 2005-02-01 | Transvivo, Inc. | Method and apparatus for therapeutic apheresis |
US7354392B2 (en) * | 2004-02-25 | 2008-04-08 | Transvivo Inc. | Structurally optimized hollow fiber membranes |
US7481917B2 (en) * | 2004-03-05 | 2009-01-27 | Hydranautics | Filtration devices with embedded radio frequency identification (RFID) tags |
DK1949915T3 (en) * | 2004-04-30 | 2012-11-26 | Biopheresis Technologies Inc | Method and system for removing soluble TNFR1, TNRF2 and IL2R in patients |
US7270655B2 (en) * | 2005-01-14 | 2007-09-18 | Haidukewych George J | Autologous material delivery apparatus and method |
EP1937386B1 (en) * | 2005-09-07 | 2013-12-25 | Hydranautics | Reverse osmosis filtration devices with rfid tag-powered flow and conductivity meters |
US20070065514A1 (en) * | 2005-09-22 | 2007-03-22 | Howell Mark D | Method for enhancing immune responses in mammals |
AU2007227628A1 (en) * | 2006-03-13 | 2007-09-27 | Hydranautics | Device for measuring permeate flow and permeate conductivity of individual reverse osmosis membrane elements |
JP5032792B2 (en) * | 2006-05-22 | 2012-09-26 | 浜松ホトニクス株式会社 | Cell sorter |
WO2007140320A2 (en) | 2006-05-26 | 2007-12-06 | Nanyang Technological University | Implantable article, method of forming same and method for reducing thrombogenicity |
US20080075690A1 (en) * | 2006-09-22 | 2008-03-27 | Mark Douglas Howell | Method for enhancing immune responses in mammals |
WO2008060788A2 (en) | 2006-10-11 | 2008-05-22 | The General Hospital Corporation | Compositions, methods, and devices for treating liver disease |
WO2008100559A2 (en) * | 2007-02-14 | 2008-08-21 | Bioengine, Inc. | Medical devices having a micro-fluidic channeled vasculature |
US8961448B2 (en) * | 2008-01-28 | 2015-02-24 | Peter Forsell | Implantable drainage device |
US8206636B2 (en) | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
US10898620B2 (en) | 2008-06-20 | 2021-01-26 | Razmodics Llc | Composite stent having multi-axial flexibility and method of manufacture thereof |
US8206635B2 (en) | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
JP2013506681A (en) | 2009-10-02 | 2013-02-28 | バクスター・インターナショナル・インコーポレイテッド | Hematopoietic stem cells for use in the treatment of kidney injury |
ES2784183T3 (en) * | 2009-12-08 | 2020-09-22 | Univ Illinois | Procedures for use and apparatus for immune modulation of stem cells |
WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
EP2463484A1 (en) | 2010-12-13 | 2012-06-13 | Siemens Aktiengesellschaft | Tubular casing for a turbo engine |
EP2817014A2 (en) | 2012-02-21 | 2014-12-31 | Baxter International Inc | Pharmaceutical composition comprising cd34+ cells |
US9414752B2 (en) | 2012-11-09 | 2016-08-16 | Elwha Llc | Embolism deflector |
ES2532030B2 (en) * | 2013-09-20 | 2015-12-28 | Universidad Complutense De Madrid | Method of measuring ex vivo vascular tone and flow chamber |
ES2860423T3 (en) | 2014-05-28 | 2021-10-05 | Childrens Hospital Med Ct | Methods and Systems for Converting Stem Cells to Gastric Tissues by Targeted Differentiation |
US11060067B2 (en) * | 2014-09-30 | 2021-07-13 | D. Lansing Taylor | Human liver microphysiology platform and self assembly liver acinus model and methods of their use |
AU2015331848B2 (en) | 2014-10-17 | 2022-03-03 | Children's Hospital Medical Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
CA3016641A1 (en) | 2016-05-05 | 2017-11-09 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
US11767515B2 (en) | 2016-12-05 | 2023-09-26 | Children's Hospital Medical Center | Colonic organoids and methods of making and using same |
CN106540345A (en) * | 2016-12-13 | 2017-03-29 | 广州奥柏仕医疗器械有限公司 | A kind of four groups of doughnut dynamic cultivation bioartificial liver's reactors |
CN108211032B (en) * | 2018-02-01 | 2023-11-17 | 南方医科大学珠江医院 | Combined bioartificial liver support system |
DE102019106651A1 (en) * | 2019-03-15 | 2020-09-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Treatment device and method for extracorporeal, immune tolerance-increasing blood treatment |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4832034A (en) * | 1987-04-09 | 1989-05-23 | Pizziconi Vincent B | Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids |
US4950224A (en) | 1988-08-05 | 1990-08-21 | Healthdyne, Inc. | Apparatus and method for in vivo plasma separation |
US5151082A (en) | 1988-08-05 | 1992-09-29 | Heathdyne, Inc. | Apparatus and method for kidney dialysis using plasma in lieu of blood |
US5224926A (en) | 1988-08-05 | 1993-07-06 | Healthdyne, Inc. | Transvivo plasma extraction catheter device |
EP0801973A1 (en) * | 1996-04-19 | 1997-10-22 | Teijin Limited | Selectively permeable hollow fiber membrane and process for producing same |
US5735809A (en) | 1996-12-05 | 1998-04-07 | Matria Healthcare, Inc. | Fiber assembly for in vivo plasma separation |
US5968004A (en) | 1997-09-23 | 1999-10-19 | Matria Healthcare, Inc. | Microporous membrane sheet plasma extraction catheter |
WO2001078805A1 (en) | 2000-04-13 | 2001-10-25 | Transvivo, Inc. | Specialized hollow fiber membranes for in-vivo plasmapheresis and ultrafiltration |
US20020087109A1 (en) * | 2001-01-04 | 2002-07-04 | Gorsuch Reynolds G. | Apparatus and method for in-vivo plasmapheresis using periodic backflush |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2656234B1 (en) | 1989-12-22 | 1992-03-20 | Hospal Ind | SEMI-PERMEABLE ASYMMETRICAL MEMBRANE FOR THE TREATMENT OF BIOLOGICAL LIQUIDS. |
US5827729A (en) * | 1996-04-23 | 1998-10-27 | Advanced Tissue Sciences | Diffusion gradient bioreactor and extracorporeal liver device using a three-dimensional liver tissue |
US5955353A (en) | 1997-05-22 | 1999-09-21 | Excorp Medical, Inc. | Hollow fiber bioreactor with an extrafilament flow plug |
US6080581A (en) * | 1998-07-02 | 2000-06-27 | Charles Daniel Anderson | Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using same |
US5989913A (en) * | 1998-07-02 | 1999-11-23 | Charles Daniel Anderson | Culture vessel for growing or culturing cells, cellular aggregates, tissues and organoids and methods for using the same |
-
2001
- 2001-05-14 US US09/858,029 patent/US6607501B2/en not_active Expired - Fee Related
-
2002
- 2002-05-10 IL IL15850702A patent/IL158507A0/en unknown
- 2002-05-10 WO PCT/US2002/015050 patent/WO2003002173A1/en not_active Application Discontinuation
- 2002-05-10 CA CA002446580A patent/CA2446580A1/en not_active Abandoned
- 2002-05-10 JP JP2003508411A patent/JP2004531349A/en active Pending
- 2002-05-10 EP EP02780945A patent/EP1387706A1/en not_active Withdrawn
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4832034A (en) * | 1987-04-09 | 1989-05-23 | Pizziconi Vincent B | Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids |
US4950224A (en) | 1988-08-05 | 1990-08-21 | Healthdyne, Inc. | Apparatus and method for in vivo plasma separation |
US5151082A (en) | 1988-08-05 | 1992-09-29 | Heathdyne, Inc. | Apparatus and method for kidney dialysis using plasma in lieu of blood |
US5224926A (en) | 1988-08-05 | 1993-07-06 | Healthdyne, Inc. | Transvivo plasma extraction catheter device |
EP0801973A1 (en) * | 1996-04-19 | 1997-10-22 | Teijin Limited | Selectively permeable hollow fiber membrane and process for producing same |
US5735809A (en) | 1996-12-05 | 1998-04-07 | Matria Healthcare, Inc. | Fiber assembly for in vivo plasma separation |
US5968004A (en) | 1997-09-23 | 1999-10-19 | Matria Healthcare, Inc. | Microporous membrane sheet plasma extraction catheter |
WO2001078805A1 (en) | 2000-04-13 | 2001-10-25 | Transvivo, Inc. | Specialized hollow fiber membranes for in-vivo plasmapheresis and ultrafiltration |
US20020087109A1 (en) * | 2001-01-04 | 2002-07-04 | Gorsuch Reynolds G. | Apparatus and method for in-vivo plasmapheresis using periodic backflush |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007500511A (en) * | 2003-05-19 | 2007-01-18 | プロバイオゲン アーゲー | Artificial immune organ |
JP4712709B2 (en) * | 2003-05-19 | 2011-06-29 | プロバイオゲン アーゲー | Artificial immune organ |
CN101102728B (en) * | 2005-01-10 | 2011-06-22 | 曲利姆医疗股份有限公司 | Stand with self-deployable portion |
Also Published As
Publication number | Publication date |
---|---|
US20020188240A1 (en) | 2002-12-12 |
CA2446580A1 (en) | 2003-01-09 |
EP1387706A1 (en) | 2004-02-11 |
JP2004531349A (en) | 2004-10-14 |
US6607501B2 (en) | 2003-08-19 |
IL158507A0 (en) | 2004-05-12 |
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