WO2003002092A3 - Controlled release composition comprising lactic acid polymer and hydroxynaphthoic acid, and method of producing the same - Google Patents
Controlled release composition comprising lactic acid polymer and hydroxynaphthoic acid, and method of producing the same Download PDFInfo
- Publication number
- WO2003002092A3 WO2003002092A3 PCT/JP2002/006527 JP0206527W WO03002092A3 WO 2003002092 A3 WO2003002092 A3 WO 2003002092A3 JP 0206527 W JP0206527 W JP 0206527W WO 03002092 A3 WO03002092 A3 WO 03002092A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- salt
- controlled release
- release composition
- weight
- active substance
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Abstract
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2455392A CA2455392C (en) | 2001-06-29 | 2002-06-28 | Controlled release composition comprising lactic acid polymer and hydroxynaphthoic acid, and method of producing the same |
IL15905902A IL159059A0 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition and method of producing the same |
NZ529969A NZ529969A (en) | 2001-06-29 | 2002-06-28 | Controlled release composition comprising lactic acid polymer, and method of producing the same |
DK02738838.8T DK1330293T4 (en) | 2001-06-29 | 2002-06-28 | Controlled release preparation comprising lactic acid polymer and process for its preparation |
KR1020037017129A KR100916173B1 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition and method of producing the same |
ES08003261T ES2366677T3 (en) | 2001-06-29 | 2002-06-28 | COMPOSITION OF CONTROLLED RELEASE AND METHOD FOR YOUR PRODUCTION. |
DE60211464T DE60211464T3 (en) | 2001-06-29 | 2002-06-28 | PHARMACEUTICAL FORMULATIONS WITH CONTROLLED ACTIVE INGREDIENT CONTAINING MILKY ACID POLYMER, AND THEIR PREPARATION |
US10/182,731 US7429559B2 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition and method of producing the same |
EP02738838A EP1330293B2 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition comprising lactic acid polymer, and method of producing the same |
BR0210561-6 BRPI0210561B8 (en) | 2001-06-29 | 2002-06-28 | controlled release composition comprising lactic acid polymer and a lh-rh derivative, method of production thereof, and drug. |
HU0400378A HU230351B1 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition containing lactic acid polymer and method of producing the same |
SK1560-2003A SK287577B6 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition, method for the preparation thereof and pharmaceutical preparation containing composition |
MXPA03011456A MXPA03011456A (en) | 2001-06-29 | 2002-06-28 | Controlled release composition comprising lactic acid polymer andhydroxynaphthoic acid, and method of producing the same. |
AU2002311631A AU2002311631B2 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition comprising lactic acid polymer and hydroxynaphthoic acid, and method of producing the same |
ZA2003/09152A ZA200309152B (en) | 2001-06-29 | 2003-11-25 | Conrolled release composition and method of producing the same |
IL159059A IL159059A (en) | 2001-06-29 | 2003-11-25 | Controlled release composition comprising an lh-rh derivative and polylactic acid, method of producing the same and medicament comprising the same |
HK03108668A HK1056332A1 (en) | 2001-06-29 | 2003-11-27 | Controlled release composition comprising lactic acid polymer, and method of producing the same |
NO20035738A NO331883B1 (en) | 2001-06-29 | 2003-12-19 | Controlled release mixture and method of preparation thereof. |
CY20061100943T CY1105071T1 (en) | 2001-06-29 | 2006-07-07 | CONTROLLED RELEASE COMPOSITION AND METHOD OF PREPARATION THEREOF |
AU2006246508A AU2006246508B2 (en) | 2001-06-29 | 2006-12-01 | Controlled release composition comprising lactic acid polymer and hydroxynaphthoic acid, and method of producing the same |
IL186782A IL186782A0 (en) | 2001-06-29 | 2007-10-18 | Controlled release composition and method of producing the same |
US12/181,472 US8067030B2 (en) | 2001-06-29 | 2008-07-29 | Controlled release composition and method of producing the same |
US13/064,282 US8246987B2 (en) | 2001-06-29 | 2011-03-16 | Controlled release composition and method of producing the same |
US13/548,463 US8815801B2 (en) | 2001-06-29 | 2012-07-13 | Controlled release composition and method of producing the same |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001199484 | 2001-06-29 | ||
JP2001-199484 | 2001-06-29 | ||
JP2001-340993 | 2001-11-06 | ||
JP2001340993 | 2001-11-06 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/182,731 A-371-Of-International US7429559B2 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition and method of producing the same |
US12/181,472 Continuation US8067030B2 (en) | 2001-06-29 | 2008-07-29 | Controlled release composition and method of producing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003002092A2 WO2003002092A2 (en) | 2003-01-09 |
WO2003002092A3 true WO2003002092A3 (en) | 2003-04-10 |
Family
ID=26617910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/006527 WO2003002092A2 (en) | 2001-06-29 | 2002-06-28 | Controlled release composition comprising lactic acid polymer and hydroxynaphthoic acid, and method of producing the same |
Country Status (34)
Country | Link |
---|---|
US (4) | US7429559B2 (en) |
EP (3) | EP1949936B1 (en) |
JP (5) | JP2003206240A (en) |
KR (2) | KR100916173B1 (en) |
CN (3) | CN1292796C (en) |
AR (2) | AR034641A1 (en) |
AT (3) | ATE326264T1 (en) |
AU (2) | AU2002311631B2 (en) |
BR (1) | BRPI0210561B8 (en) |
CA (1) | CA2455392C (en) |
CO (1) | CO5540367A2 (en) |
CR (1) | CR11283A (en) |
CY (2) | CY1105071T1 (en) |
CZ (1) | CZ306327B6 (en) |
DE (2) | DE60211464T3 (en) |
DK (2) | DK1949936T3 (en) |
ES (2) | ES2263788T5 (en) |
HK (1) | HK1056332A1 (en) |
HU (1) | HU230351B1 (en) |
IL (3) | IL159059A0 (en) |
MX (1) | MXPA03011456A (en) |
MY (1) | MY142066A (en) |
NO (1) | NO331883B1 (en) |
NZ (2) | NZ529969A (en) |
PE (1) | PE20030066A1 (en) |
PL (1) | PL204903B1 (en) |
PT (2) | PT1949936E (en) |
RU (1) | RU2301661C2 (en) |
SG (1) | SG180015A1 (en) |
SI (1) | SI1949936T1 (en) |
SK (1) | SK287577B6 (en) |
TW (2) | TW200526267A (en) |
WO (1) | WO2003002092A2 (en) |
ZA (1) | ZA200309152B (en) |
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DK1532985T3 (en) * | 2002-06-25 | 2016-12-05 | Takeda Pharmaceuticals Co | PROCEDURE FOR PREPARING A COMPOSITION WITH LONG-TERM RELEASE |
AU2004253853B2 (en) * | 2003-04-10 | 2010-04-01 | Evonik Corporation | A method for the production of emulsion-based micro particles |
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BRPI0412059A (en) * | 2003-07-15 | 2006-09-05 | Pr Pharmaceuticals Inc | Method for preparing controlled release formulation |
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TW200529890A (en) * | 2004-02-10 | 2005-09-16 | Takeda Pharmaceutical | Sustained-release preparations |
TW200613012A (en) * | 2004-07-02 | 2006-05-01 | Takeda Pharmaceuticals Co | Sustained-release composition, process for producing the same and use of the same |
US20060251581A1 (en) * | 2005-05-09 | 2006-11-09 | Mcintyre Jon T | Method for treatment of uterine fibroid tumors |
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US7858663B1 (en) * | 2007-10-31 | 2010-12-28 | Pisgah Laboratories, Inc. | Physical and chemical properties of thyroid hormone organic acid addition salts |
CA2671670C (en) * | 2006-12-18 | 2015-02-10 | Takeda Pharmaceutical Company Limited | Sustained-release composition and method for producing the same |
US20110319987A1 (en) * | 2009-05-20 | 2011-12-29 | Arsenal Medical | Medical implant |
KR101811797B1 (en) * | 2013-04-03 | 2017-12-22 | 동국제약 주식회사 | Pharmaceutical composition comprising donepezil for parenteral administration |
US20160303242A1 (en) | 2013-12-09 | 2016-10-20 | Durect Corporation | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same |
CN103751851A (en) * | 2014-01-17 | 2014-04-30 | 东华大学 | Preparation method of inorganic/organic multi-drug controlled release composite nano fiber scaffold |
KR101558083B1 (en) * | 2014-04-07 | 2015-10-07 | 에스케이케미칼주식회사 | Method for producing microspheres loaded with drugs |
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2002
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WO2000035990A1 (en) * | 1998-12-15 | 2000-06-22 | Takeda Chemical Industries, Ltd. | Process for producing polymer |
WO2001005380A1 (en) * | 1999-07-15 | 2001-01-25 | Takeda Chemical Industries, Ltd. | Sustained release compositions, process for producing the same and use thereof |
WO2002043766A1 (en) * | 2000-11-29 | 2002-06-06 | Takeda Chemical Industries, Ltd. | Medicinal compositions and process for producing the same |
WO2002047722A1 (en) * | 2000-12-15 | 2002-06-20 | Takeda Chemical Industries, Ltd. | Medicinal compositions of nonpeptidyl gonadotropin-releasing hormone agonist or antagonist, process for producing the same and use thereof |
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DATABASE WPI Section Ch Week 200264, Derwent World Patents Index; Class A96, AN 2002-599485, XP002224756 * |
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