WO2003000023A3 - Method of treating hyperproliferative diseases using active vitamin d analogues - Google Patents

Method of treating hyperproliferative diseases using active vitamin d analogues Download PDF

Info

Publication number
WO2003000023A3
WO2003000023A3 PCT/US2002/020475 US0220475W WO03000023A3 WO 2003000023 A3 WO2003000023 A3 WO 2003000023A3 US 0220475 W US0220475 W US 0220475W WO 03000023 A3 WO03000023 A3 WO 03000023A3
Authority
WO
WIPO (PCT)
Prior art keywords
analogues
hyperproliferative diseases
active vitamin
treating hyperproliferative
vitamin
Prior art date
Application number
PCT/US2002/020475
Other languages
French (fr)
Other versions
WO2003000023A2 (en
Inventor
Charles W Bishop
Richard B Mazess
Original Assignee
Bone Care Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bone Care Int Inc filed Critical Bone Care Int Inc
Priority to IL15906802A priority Critical patent/IL159068A0/en
Priority to CA002450942A priority patent/CA2450942A1/en
Priority to KR10-2003-7016888A priority patent/KR20040015753A/en
Priority to MXPA03011307A priority patent/MXPA03011307A/en
Priority to EP02756332A priority patent/EP1408983A4/en
Priority to JP2003506479A priority patent/JP2004535429A/en
Priority to AU2002322346A priority patent/AU2002322346B2/en
Publication of WO2003000023A2 publication Critical patent/WO2003000023A2/en
Publication of WO2003000023A3 publication Critical patent/WO2003000023A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Methods for the utilization of hypocalcemic vitamin D analogy to inhibit the hyperproliferation of malignant or neoplastic cells without incidence of hypercalcemia.
PCT/US2002/020475 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin d analogues WO2003000023A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IL15906802A IL159068A0 (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin d analogues
CA002450942A CA2450942A1 (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin d analogues
KR10-2003-7016888A KR20040015753A (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin D analogues
MXPA03011307A MXPA03011307A (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin d analogues.
EP02756332A EP1408983A4 (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin d analogues
JP2003506479A JP2004535429A (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative disease using active vitamin D analogs
AU2002322346A AU2002322346B2 (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin D analogues

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/891,814 US6503893B2 (en) 1996-12-30 2001-06-26 Method of treating hyperproliferative diseases using active vitamin D analogues
US09/891,814 2001-06-26

Publications (2)

Publication Number Publication Date
WO2003000023A2 WO2003000023A2 (en) 2003-01-03
WO2003000023A3 true WO2003000023A3 (en) 2003-07-31

Family

ID=25398862

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/020475 WO2003000023A2 (en) 2001-06-26 2002-06-26 Method of treating hyperproliferative diseases using active vitamin d analogues

Country Status (10)

Country Link
US (2) US6503893B2 (en)
EP (1) EP1408983A4 (en)
JP (1) JP2004535429A (en)
KR (1) KR20040015753A (en)
CN (1) CN1234366C (en)
AU (1) AU2002322346B2 (en)
CA (1) CA2450942A1 (en)
IL (1) IL159068A0 (en)
MX (1) MXPA03011307A (en)
WO (1) WO2003000023A2 (en)

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US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
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US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
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US7914810B2 (en) * 2005-05-06 2011-03-29 Synthes Usa, Llc Methods for the in situ treatment of bone cancer
CA2882048C (en) 2006-02-03 2020-03-24 Proventiv Therapeutics, Llc Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
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TW200833345A (en) * 2006-11-01 2008-08-16 Novacea Inc Use of vitamin D compounds and mimics thereof to enhance delivery of therapeutics and oxygen to tumors and other tissues
US8501717B2 (en) * 2007-02-09 2013-08-06 Merck, Sharp & Dohme Corp. Methods to treat and/or prevent mucositis
KR20190028822A (en) 2007-04-25 2019-03-19 사이토크로마 인코포레이티드 Oral controlled release compositions comprising vitamin d compound and waxy carrier
WO2009047644A2 (en) 2007-04-25 2009-04-16 Cytochroma Inc. Method of treating vitamin d insufficiency and deficiency
WO2008134523A1 (en) * 2007-04-25 2008-11-06 Proventiv Therapeutics, Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
US8962239B2 (en) 2008-04-02 2015-02-24 Opko Renal, Llc Methods useful for vitamin D deficiency and related disorders
US20100009934A1 (en) * 2008-06-09 2010-01-14 Combinatorx, Incorporated Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders
EA026334B1 (en) * 2009-01-27 2017-03-31 БЕРГ ЭлЭлСи Use of vitamin d compound for preventing or reducing chemotherapy-induced neutropenia
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PT2552484T (en) 2010-03-29 2020-04-03 Opko Ireland Global Holdings Ltd Methods and compositions for reducing parathyroid levels
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Also Published As

Publication number Publication date
EP1408983A2 (en) 2004-04-21
CN1520302A (en) 2004-08-11
JP2004535429A (en) 2004-11-25
AU2002322346B2 (en) 2006-10-26
KR20040015753A (en) 2004-02-19
IL159068A0 (en) 2004-05-12
US6680309B2 (en) 2004-01-20
WO2003000023A2 (en) 2003-01-03
EP1408983A4 (en) 2007-05-09
US20030130242A1 (en) 2003-07-10
CA2450942A1 (en) 2003-01-03
MXPA03011307A (en) 2004-06-08
US6503893B2 (en) 2003-01-07
US20020025950A1 (en) 2002-02-28
CN1234366C (en) 2006-01-04

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