WO2002103323A3 - Microfluidic systems with enhanced detection systems - Google Patents
Microfluidic systems with enhanced detection systems Download PDFInfo
- Publication number
- WO2002103323A3 WO2002103323A3 PCT/US2002/004480 US0204480W WO02103323A3 WO 2002103323 A3 WO2002103323 A3 WO 2002103323A3 US 0204480 W US0204480 W US 0204480W WO 02103323 A3 WO02103323 A3 WO 02103323A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- systems
- enhanced detection
- microfluidic
- detection systems
- enhanced
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0874—Three dimensional network
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optical Measuring Cells (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003505591A JP2004530894A (en) | 2001-02-15 | 2002-02-14 | Microfluidic system with enhanced detection system |
DE60234572T DE60234572D1 (en) | 2001-02-15 | 2002-02-14 | MICROFLUIDIC SYSTEMS WITH IMPROVED DETECTION SYSTEMS |
AT02763187T ATE450791T1 (en) | 2001-02-15 | 2002-02-14 | MICROFLUIDIC SYSTEMS WITH IMPROVED DETECTION SYSTEMS |
EP02763187A EP1360472B1 (en) | 2001-02-15 | 2002-02-14 | Microfluidic systems with enhanced detection systems |
AU2002327165A AU2002327165B2 (en) | 2001-02-15 | 2002-02-14 | Microfluidic systems with enhanced detection systems |
CA002434725A CA2434725A1 (en) | 2001-02-15 | 2002-02-14 | Microfluidic systems with enhanced detection systems |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26917401P | 2001-02-15 | 2001-02-15 | |
US60/269,174 | 2001-02-15 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002103323A2 WO2002103323A2 (en) | 2002-12-27 |
WO2002103323A3 true WO2002103323A3 (en) | 2003-02-27 |
Family
ID=23026113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/004480 WO2002103323A2 (en) | 2001-02-15 | 2002-02-14 | Microfluidic systems with enhanced detection systems |
Country Status (8)
Country | Link |
---|---|
US (1) | US20020180963A1 (en) |
EP (1) | EP1360472B1 (en) |
JP (1) | JP2004530894A (en) |
AT (1) | ATE450791T1 (en) |
AU (1) | AU2002327165B2 (en) |
CA (1) | CA2434725A1 (en) |
DE (1) | DE60234572D1 (en) |
WO (1) | WO2002103323A2 (en) |
Families Citing this family (26)
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GB2395006A (en) * | 2002-10-29 | 2004-05-12 | Micro Chemical Systems Ltd | Apparatus and method for performing an assay |
DE10361073A1 (en) * | 2003-12-22 | 2005-07-21 | Innovatis Ag | Method and device for taking microscopic images |
DE102004015906B4 (en) * | 2004-03-31 | 2006-02-16 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Microfluidic apparatus for use in optical analysis comprises substrate containing fluid channels or reservoirs and optical components, e.g. transmission gratings, for dividing or filtering light which has been refracted by substrate |
JP4626276B2 (en) * | 2004-11-18 | 2011-02-02 | ウシオ電機株式会社 | Microchip inspection device |
US8647590B2 (en) * | 2006-03-16 | 2014-02-11 | Agilent Technologies, Inc. | Optical detection cell with micro-fluidic chip |
US20070218454A1 (en) * | 2006-03-16 | 2007-09-20 | Brennen Reid A | Optical detection cell for micro-fluidics |
US8064063B2 (en) * | 2006-07-20 | 2011-11-22 | Trinean Nv | Optical characterisation methods and systems |
EP1881318A1 (en) * | 2006-07-20 | 2008-01-23 | Universiteit Gent | Optical characterisation methods and systems |
US8016260B2 (en) | 2007-07-19 | 2011-09-13 | Formulatrix, Inc. | Metering assembly and method of dispensing fluid |
US8120769B2 (en) * | 2007-08-03 | 2012-02-21 | North Carolina State University | Method and system for fiber properties measurement |
JP5157629B2 (en) * | 2008-05-14 | 2013-03-06 | ソニー株式会社 | Channel substrate |
US9678005B1 (en) | 2008-12-03 | 2017-06-13 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Devices and methods for detection of microorganisms |
US9562855B1 (en) | 2009-12-03 | 2017-02-07 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Devices and methods for detection of microorganisms via MIE scattering |
US8100293B2 (en) | 2009-01-23 | 2012-01-24 | Formulatrix, Inc. | Microfluidic dispensing assembly |
US9700889B2 (en) * | 2009-11-23 | 2017-07-11 | Cyvek, Inc. | Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results |
US9759718B2 (en) | 2009-11-23 | 2017-09-12 | Cyvek, Inc. | PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use |
US9651568B2 (en) | 2009-11-23 | 2017-05-16 | Cyvek, Inc. | Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays |
US9855735B2 (en) | 2009-11-23 | 2018-01-02 | Cyvek, Inc. | Portable microfluidic assay devices and methods of manufacture and use |
US10065403B2 (en) | 2009-11-23 | 2018-09-04 | Cyvek, Inc. | Microfluidic assay assemblies and methods of manufacture |
US9500645B2 (en) | 2009-11-23 | 2016-11-22 | Cyvek, Inc. | Micro-tube particles for microfluidic assays and methods of manufacture |
CN106552682B (en) | 2011-03-22 | 2020-06-19 | 西维克公司 | Microfluidic device and methods of manufacture and use |
CN102507419B (en) * | 2011-10-27 | 2013-07-03 | 江苏苏净集团有限公司 | Sample tank for liquid particle counter and production method of sample tank |
KR102114734B1 (en) | 2012-03-08 | 2020-05-25 | 싸이벡, 아이엔씨 | Micro-tube particles for microfluidic assays and methods of manufacture |
US10228367B2 (en) | 2015-12-01 | 2019-03-12 | ProteinSimple | Segmented multi-use automated assay cartridge |
EP3396355A1 (en) * | 2017-04-27 | 2018-10-31 | Pharmafluidics NV | Lateral detection of fluid properties |
CN112236218B (en) | 2018-04-02 | 2022-04-26 | 滴管公司 | System and method for continuous flow emulsion processing |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US5928880A (en) * | 1992-05-01 | 1999-07-27 | Trustees Of The University Of Pennsylvania | Mesoscale sample preparation device and systems for determination and processing of analytes |
WO1999044217A1 (en) * | 1998-02-24 | 1999-09-02 | Caliper Technologies Corporation | Microfluidic devices and systems incorporating integrated optical elements |
WO2001020309A1 (en) * | 1999-09-13 | 2001-03-22 | Aclara Biosciences, Inc. | Side light activated microfluid channels |
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CH542437A (en) * | 1971-08-27 | 1973-09-30 | Micromedic Systems Inc | Optical cuvette and method for its manufacture |
DE2904909C3 (en) * | 1979-02-09 | 1981-11-12 | Fa. Carl Zeiss, 7920 Heidenheim | Cell for optical measurements |
US4390403A (en) * | 1981-07-24 | 1983-06-28 | Batchelder J Samuel | Method and apparatus for dielectrophoretic manipulation of chemical species |
US4908112A (en) * | 1988-06-16 | 1990-03-13 | E. I. Du Pont De Nemours & Co. | Silicon semiconductor wafer for analyzing micronic biological samples |
US5126022A (en) * | 1990-02-28 | 1992-06-30 | Soane Tecnologies, Inc. | Method and device for moving molecules by the application of a plurality of electrical fields |
US5750015A (en) * | 1990-02-28 | 1998-05-12 | Soane Biosciences | Method and device for moving molecules by the application of a plurality of electrical fields |
EP0488947B1 (en) * | 1990-11-26 | 1995-02-15 | Ciba-Geigy Ag | Detector cell |
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US5885470A (en) * | 1997-04-14 | 1999-03-23 | Caliper Technologies Corporation | Controlled fluid transport in microfabricated polymeric substrates |
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US5779868A (en) * | 1996-06-28 | 1998-07-14 | Caliper Technologies Corporation | Electropipettor and compensation means for electrophoretic bias |
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US5800690A (en) * | 1996-07-03 | 1998-09-01 | Caliper Technologies Corporation | Variable control of electroosmotic and/or electrophoretic forces within a fluid-containing structure via electrical forces |
US5699157A (en) * | 1996-07-16 | 1997-12-16 | Caliper Technologies Corp. | Fourier detection of species migrating in a microchannel |
US6120666A (en) * | 1996-09-26 | 2000-09-19 | Ut-Battelle, Llc | Microfabricated device and method for multiplexed electrokinetic focusing of fluid streams and a transport cytometry method using same |
US5858187A (en) * | 1996-09-26 | 1999-01-12 | Lockheed Martin Energy Systems, Inc. | Apparatus and method for performing electrodynamic focusing on a microchip |
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US6224830B1 (en) * | 1998-01-30 | 2001-05-01 | The Governors Of The University Of Alberta | Absorbance cell for microfluid devices |
US6062261A (en) * | 1998-12-16 | 2000-05-16 | Lockheed Martin Energy Research Corporation | MicrofluIdic circuit designs for performing electrokinetic manipulations that reduce the number of voltage sources and fluid reservoirs |
-
2002
- 2002-02-14 JP JP2003505591A patent/JP2004530894A/en active Pending
- 2002-02-14 CA CA002434725A patent/CA2434725A1/en not_active Abandoned
- 2002-02-14 DE DE60234572T patent/DE60234572D1/en not_active Expired - Lifetime
- 2002-02-14 AT AT02763187T patent/ATE450791T1/en not_active IP Right Cessation
- 2002-02-14 AU AU2002327165A patent/AU2002327165B2/en not_active Ceased
- 2002-02-14 EP EP02763187A patent/EP1360472B1/en not_active Expired - Lifetime
- 2002-02-14 WO PCT/US2002/004480 patent/WO2002103323A2/en active Application Filing
- 2002-02-14 US US10/076,136 patent/US20020180963A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5928880A (en) * | 1992-05-01 | 1999-07-27 | Trustees Of The University Of Pennsylvania | Mesoscale sample preparation device and systems for determination and processing of analytes |
WO1999044217A1 (en) * | 1998-02-24 | 1999-09-02 | Caliper Technologies Corporation | Microfluidic devices and systems incorporating integrated optical elements |
WO2001020309A1 (en) * | 1999-09-13 | 2001-03-22 | Aclara Biosciences, Inc. | Side light activated microfluid channels |
Also Published As
Publication number | Publication date |
---|---|
CA2434725A1 (en) | 2002-12-27 |
JP2004530894A (en) | 2004-10-07 |
ATE450791T1 (en) | 2009-12-15 |
AU2002327165B2 (en) | 2006-08-10 |
US20020180963A1 (en) | 2002-12-05 |
WO2002103323A2 (en) | 2002-12-27 |
EP1360472B1 (en) | 2009-12-02 |
EP1360472A4 (en) | 2004-11-10 |
DE60234572D1 (en) | 2010-01-14 |
EP1360472A2 (en) | 2003-11-12 |
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