WO2002078602A3 - Transdermal delivery of pergolide - Google Patents

Transdermal delivery of pergolide Download PDF

Info

Publication number
WO2002078602A3
WO2002078602A3 PCT/US2002/010057 US0210057W WO02078602A3 WO 2002078602 A3 WO2002078602 A3 WO 2002078602A3 US 0210057 W US0210057 W US 0210057W WO 02078602 A3 WO02078602 A3 WO 02078602A3
Authority
WO
WIPO (PCT)
Prior art keywords
transdermal delivery
affixed
face
pergolide
matrix
Prior art date
Application number
PCT/US2002/010057
Other languages
French (fr)
Other versions
WO2002078602A2 (en
Inventor
Debra A Martin
Jesus Miranda
Adolfo Leonel Vanegas
Original Assignee
Elan Transdermal Technologies
Debra A Martin
Jesus Miranda
Adolfo Leonel Vanegas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Transdermal Technologies, Debra A Martin, Jesus Miranda, Adolfo Leonel Vanegas filed Critical Elan Transdermal Technologies
Priority to JP2002576871A priority Critical patent/JP2005506297A/en
Priority to CA002443128A priority patent/CA2443128A1/en
Priority to EP02757900A priority patent/EP1385459A2/en
Priority to US10/473,511 priority patent/US20040120995A1/en
Publication of WO2002078602A2 publication Critical patent/WO2002078602A2/en
Publication of WO2002078602A3 publication Critical patent/WO2002078602A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

A transdermal delivery device comprising a multi-phase matrix which includes a solid liquid-retaining member and associated therewith pergolide in liquid form, for example, a transdermal delivery device comprising a barrier layer affixed to one face of the matrix and having an exposed face, the exposed face having affixed thereto a mounting layer, and the other face of the matrix having affixed thereto a removable layer, an example of the liquid-retaining member being an absorbent material, for example, a natural or synthetic fiber gauze, a non-woven medical basorbent, a natural sponge, and a synthetic sponge.
PCT/US2002/010057 2001-03-30 2002-04-01 Transdermal delivery of pergolide WO2002078602A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002576871A JP2005506297A (en) 2001-03-30 2002-04-01 Pergolide transdermal delivery
CA002443128A CA2443128A1 (en) 2001-03-30 2002-04-01 Transdermal delivery of pergolide
EP02757900A EP1385459A2 (en) 2001-03-30 2002-04-01 Transdermal delivery of pergolide
US10/473,511 US20040120995A1 (en) 2002-04-01 2002-04-01 Transdermal delivery of pergolide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28053301P 2001-03-30 2001-03-30
US60/280,533 2001-03-30

Publications (2)

Publication Number Publication Date
WO2002078602A2 WO2002078602A2 (en) 2002-10-10
WO2002078602A3 true WO2002078602A3 (en) 2003-02-20

Family

ID=23073490

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/010057 WO2002078602A2 (en) 2001-03-30 2002-04-01 Transdermal delivery of pergolide

Country Status (4)

Country Link
EP (1) EP1385459A2 (en)
JP (1) JP2005506297A (en)
CA (1) CA2443128A1 (en)
WO (1) WO2002078602A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US9248136B2 (en) 2011-11-23 2016-02-02 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US9289382B2 (en) 2012-06-18 2016-03-22 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070243240A9 (en) * 2000-08-24 2007-10-18 Fred Windt-Hanke Transdermal therapeutic system
DE10341317B4 (en) * 2003-09-03 2008-10-23 Axxonis Pharma Ag Transdermal therapeutic system (TTS) for administration of ergoline compounds except pergolide
TW200514582A (en) * 2003-10-31 2005-05-01 Hisamitsu Pharmaceutical Co Transdermal preparation and method for reducing side effect in pergolide therapy
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
KR20170005819A (en) 2014-05-22 2017-01-16 쎄러퓨틱스엠디, 인코퍼레이티드 Natural combination hormone replacement formulations and therapies
US9987267B2 (en) * 2014-06-18 2018-06-05 Elanco Us Inc. Transdermal formulations of pergolide and uses thereof
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
AU2017239645A1 (en) 2016-04-01 2018-10-18 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486362A (en) * 1991-05-07 1996-01-23 Dynagen, Inc. Controlled, sustained release delivery system for treating drug dependency
WO1996040139A1 (en) * 1995-06-07 1996-12-19 Alza Corporation Novel formulations for transdermal delivery of pergolide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486362A (en) * 1991-05-07 1996-01-23 Dynagen, Inc. Controlled, sustained release delivery system for treating drug dependency
WO1996040139A1 (en) * 1995-06-07 1996-12-19 Alza Corporation Novel formulations for transdermal delivery of pergolide

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9248136B2 (en) 2011-11-23 2016-02-02 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US9289382B2 (en) 2012-06-18 2016-03-22 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion

Also Published As

Publication number Publication date
WO2002078602A2 (en) 2002-10-10
CA2443128A1 (en) 2002-10-10
EP1385459A2 (en) 2004-02-04
JP2005506297A (en) 2005-03-03

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