WO2002077264A3 - Arrayed transfection method and uses related thereto - Google Patents
Arrayed transfection method and uses related thereto Download PDFInfo
- Publication number
- WO2002077264A3 WO2002077264A3 PCT/US2002/009265 US0209265W WO02077264A3 WO 2002077264 A3 WO2002077264 A3 WO 2002077264A3 US 0209265 W US0209265 W US 0209265W WO 02077264 A3 WO02077264 A3 WO 02077264A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- transfection method
- uses related
- arrayed
- arrayed transfection
- interest
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002575306A JP2004530426A (en) | 2001-03-22 | 2002-03-22 | Arrayed transfection methods and uses related to said methods |
EP02725351A EP1379642A4 (en) | 2001-03-22 | 2002-03-22 | Arrayed transfection method and uses related thereto |
CA002440378A CA2440378A1 (en) | 2001-03-22 | 2002-03-22 | Arrayed transfection method and uses related thereto |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/817,003 US20020006664A1 (en) | 1999-09-17 | 2001-03-22 | Arrayed transfection method and uses related thereto |
US09/817,003 | 2001-03-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002077264A2 WO2002077264A2 (en) | 2002-10-03 |
WO2002077264A3 true WO2002077264A3 (en) | 2003-02-20 |
Family
ID=25222147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/009265 WO2002077264A2 (en) | 2001-03-22 | 2002-03-22 | Arrayed transfection method and uses related thereto |
Country Status (5)
Country | Link |
---|---|
US (4) | US20020006664A1 (en) |
EP (1) | EP1379642A4 (en) |
JP (1) | JP2004530426A (en) |
CA (1) | CA2440378A1 (en) |
WO (1) | WO2002077264A2 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8883988B2 (en) | 1999-03-02 | 2014-11-11 | Life Technologies Corporation | Compositions for use in recombinational cloning of nucleic acids |
US8945884B2 (en) | 2000-12-11 | 2015-02-03 | Life Technologies Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites |
US9534252B2 (en) | 2003-12-01 | 2017-01-03 | Life Technologies Corporation | Nucleic acid molecules containing recombination sites and methods of using the same |
Families Citing this family (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69836092T2 (en) * | 1997-10-24 | 2007-05-10 | Invitrogen Corp., Carlsbad | RECOMBINATORY CLONING USING NUCLEAR FACILITIES WITH RECOMBINATION CENTERS |
US20020006664A1 (en) * | 1999-09-17 | 2002-01-17 | Sabatini David M. | Arrayed transfection method and uses related thereto |
DE10024334B4 (en) * | 2000-05-17 | 2006-06-01 | Medigene Ag | Method for introducing nucleic acid into a cell (transfection) by means of calcium phosphate |
US6897067B2 (en) * | 2000-11-03 | 2005-05-24 | Regents Of The University Of Michigan | Surface transfection and expression procedure |
US6902933B2 (en) * | 2000-11-03 | 2005-06-07 | Regents Of The University Of Michigan | Surface transfection and expression procedure |
US20040132008A1 (en) * | 2002-04-30 | 2004-07-08 | Doranz Benjamin J | Elucidation of gene function |
US20070111201A1 (en) * | 2001-04-30 | 2007-05-17 | Benjamin Doranz | Reverse transfection of cell arrays for structural and functional analyses of proteins |
US7294504B1 (en) | 2001-12-27 | 2007-11-13 | Allele Biotechnology & Pharmaceuticals, Inc. | Methods and compositions for DNA mediated gene silencing |
CA2482485A1 (en) * | 2002-04-15 | 2003-10-30 | Merck & Co., Inc. | Matrix analysis of gene expression in cells (magec) |
AU2003241871A1 (en) * | 2002-05-28 | 2003-12-12 | National Institute Of Advanced Industrial Science And Technology | Chemical sensor system |
US7900836B2 (en) * | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Optical reader system for substrates having an optically readable code |
US7872804B2 (en) * | 2002-08-20 | 2011-01-18 | Illumina, Inc. | Encoded particle having a grating with variations in the refractive index |
US7164533B2 (en) | 2003-01-22 | 2007-01-16 | Cyvera Corporation | Hybrid random bead/chip based microarray |
US7399643B2 (en) * | 2002-09-12 | 2008-07-15 | Cyvera Corporation | Method and apparatus for aligning microbeads in order to interrogate the same |
US7508608B2 (en) * | 2004-11-17 | 2009-03-24 | Illumina, Inc. | Lithographically fabricated holographic optical identification element |
US7901630B2 (en) * | 2002-08-20 | 2011-03-08 | Illumina, Inc. | Diffraction grating-based encoded microparticle assay stick |
US7923260B2 (en) | 2002-08-20 | 2011-04-12 | Illumina, Inc. | Method of reading encoded particles |
US20050227252A1 (en) * | 2002-08-20 | 2005-10-13 | Moon John A | Diffraction grating-based encoded articles for multiplexed experiments |
US20040048260A1 (en) * | 2002-09-10 | 2004-03-11 | Fu-Hsiung Chang | Transfection of nucleic acid |
US7092160B2 (en) * | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
US20100255603A9 (en) * | 2002-09-12 | 2010-10-07 | Putnam Martin A | Method and apparatus for aligning microbeads in order to interrogate the same |
US20030153013A1 (en) * | 2002-11-07 | 2003-08-14 | Ruo-Pan Huang | Antibody-based protein array system |
US6905878B2 (en) * | 2002-12-19 | 2005-06-14 | The Scripps Research Institute | DNA array for high throughput solid-phase transfection and method for producing the same |
US20060135940A1 (en) * | 2003-01-06 | 2006-06-22 | The Trustees Of Columbia | Programmed pulsed infusion methods and devices |
US20060047261A1 (en) * | 2004-06-28 | 2006-03-02 | Shailendra Joshi | Intra-arterial catheter for drug delivery |
US20040138154A1 (en) * | 2003-01-13 | 2004-07-15 | Lei Yu | Solid surface for biomolecule delivery and high-throughput assay |
US20070269891A9 (en) * | 2003-01-13 | 2007-11-22 | Yasunobu Tanaka | Solid surface with immobilized degradable cationic polymer for transfecting eukaryotic cells |
US20040147027A1 (en) * | 2003-01-28 | 2004-07-29 | Troy Carol M. | Complex for facilitating delivery of dsRNA into a cell and uses thereof |
DE502004007131D1 (en) * | 2003-03-04 | 2008-06-26 | Nmi Univ Tuebingen | METHOD FOR PRODUCING A CARRIER WITH IMMOBILIZED VIRUSES AND USE OF SUCH A CARRIER |
WO2004079331A2 (en) * | 2003-03-04 | 2004-09-16 | National Institute Of Advanced Industrial Science And Technology | Composition and method for immobilizing a substance on a solid-phase support |
JP2006522605A (en) * | 2003-03-04 | 2006-10-05 | 独立行政法人産業技術総合研究所 | Time-lapse cell analysis |
EP1608729A4 (en) * | 2003-03-05 | 2007-03-07 | Univ Leland Stanford Junior | Rnai arrays and methods for using the same |
WO2004078950A2 (en) * | 2003-03-05 | 2004-09-16 | The Board Of Trustees Of The Leland Stanford Junior University | METHODS AND COMPOSITIONS FOR SELECTIVE RNAi MEDIATED INHIBITION OF GENE EXPRESSION IN MAMMAL CELLS |
US8158420B2 (en) * | 2003-04-04 | 2012-04-17 | The Trustees Of Columbia University In The City Of New York | Methods for inhibiting the differentation of proliferative telencephalic cells in vitro by addition of ATF5 |
US20050164384A1 (en) * | 2003-04-04 | 2005-07-28 | Greene Lloyd A. | Methods for regulating differentiation of neural cells and uses thereof |
JP2007516230A (en) * | 2003-05-19 | 2007-06-21 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | Compositions and methods for treating and preventing degeneration of heart tissue and uses thereof |
US7760927B2 (en) * | 2003-09-10 | 2010-07-20 | Bioimagene, Inc. | Method and system for digital image based tissue independent simultaneous nucleus cytoplasm and membrane quantitation |
WO2005026322A2 (en) * | 2003-09-11 | 2005-03-24 | Clontech Laboratories, Inc. | siRNA ENCODING CONSTRUCTS AND METHODS FOR USING THE SAME |
US20050059019A1 (en) * | 2003-09-11 | 2005-03-17 | Sven Bulow | Gene-related RNAi transfection method |
US20060057729A1 (en) * | 2003-09-12 | 2006-03-16 | Illumina, Inc. | Diffraction grating-based encoded element having a substance disposed thereon |
ATE370240T1 (en) * | 2003-10-10 | 2007-09-15 | Sumitomo Chemical Co | TRANSFORMED CELLS CO-EXPRESSING A CYTOKININ RECEPTOR AND A CYTOKININ BIOSYNTHESIS ENZYME |
US7553631B2 (en) * | 2003-12-11 | 2009-06-30 | Beth Israel Deaconess Medical Center, Inc. | RBP4 in insulin sensitivity/resistance, diabetes, and obesity |
EP1696034A4 (en) * | 2003-12-19 | 2006-12-27 | Dainippon Sumitomo Pharma Co | Novel method of nucleic acid transfer |
DE602005017362D1 (en) * | 2004-02-06 | 2009-12-10 | Dharmacon Inc | STABILIZED RNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS |
US20090280567A1 (en) * | 2004-02-06 | 2009-11-12 | Dharmacon, Inc. | Stabilized sirnas as transfection controls and silencing reagents |
US7125709B2 (en) * | 2004-02-10 | 2006-10-24 | Nitto Denko Corporation | Culture device and method for eukaryotic cell transfection |
US7433123B2 (en) * | 2004-02-19 | 2008-10-07 | Illumina, Inc. | Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein |
US20060019915A1 (en) * | 2004-02-25 | 2006-01-26 | Fanzo Jessica C | Method to modulate the immune system with a novel guanine nucleotide exchange factor |
KR101147147B1 (en) * | 2004-04-01 | 2012-05-25 | 머크 샤프 앤드 돔 코포레이션 | Modified polynucleotides for reducing off-target effects in rna interference |
US20050281782A1 (en) * | 2004-06-21 | 2005-12-22 | Howard Kaufman | Novel recombinant poxvirus composition and uses thereof |
JP2007267602A (en) * | 2004-06-25 | 2007-10-18 | National Institute Of Advanced Industrial & Technology | Method and composition for transferring nucleic acid into cell on solid phase and differentiating and inducing the same cell |
US20070162989A1 (en) * | 2004-07-14 | 2007-07-12 | Kottmann Andreas H | Methods and compositions for treating motor neuron associated disorders |
WO2006020363A2 (en) * | 2004-07-21 | 2006-02-23 | Illumina, Inc. | Method and apparatus for drug product tracking using encoded optical identification elements |
US20080020466A1 (en) * | 2004-08-17 | 2008-01-24 | Bml, Inc. | Detection Method Using Detecting Device |
US7358223B2 (en) * | 2004-10-04 | 2008-04-15 | Nitto Denko Corporation | Biodegradable cationic polymers |
EP2194485B1 (en) | 2004-11-16 | 2012-10-17 | Illumina, Inc. | Method and apparatus for reading coded microbeads |
WO2006055735A2 (en) * | 2004-11-16 | 2006-05-26 | Illumina, Inc | Scanner having spatial light modulator |
US7604173B2 (en) * | 2004-11-16 | 2009-10-20 | Illumina, Inc. | Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same |
US20060166234A1 (en) * | 2004-11-22 | 2006-07-27 | Barbara Robertson | Apparatus and system having dry control gene silencing compositions |
EP1814895B1 (en) * | 2004-11-22 | 2011-08-10 | Dharmacon, Inc. | Apparatus and system having dry control gene silencing compositions |
US7935811B2 (en) * | 2004-11-22 | 2011-05-03 | Dharmacon, Inc. | Apparatus and system having dry gene silencing compositions |
US7923207B2 (en) | 2004-11-22 | 2011-04-12 | Dharmacon, Inc. | Apparatus and system having dry gene silencing pools |
CN101124316A (en) * | 2004-12-17 | 2008-02-13 | 日东电工株式会社 | Fixed degradable cationic polymer for transfecting eukaryotic cells |
US7537913B2 (en) * | 2005-01-21 | 2009-05-26 | Falcon Genomics, Inc. | High throughput assay for cancer cell growth inhibition |
US20060223777A1 (en) * | 2005-03-29 | 2006-10-05 | Dharmacon, Inc. | Highly functional short hairpin RNA |
WO2006110358A2 (en) * | 2005-04-01 | 2006-10-19 | Invitrogen Corporation | Methods and compositions for introducing biopolymers into cells |
US20060223184A1 (en) * | 2005-04-05 | 2006-10-05 | Frutos Anthony G | Supports useful in incorporating biomolecules into cells and methods of using thereof |
CA2619139C (en) * | 2005-09-09 | 2013-06-25 | Jianhui Rong | Cell-based microarrays and methods of use |
CA2660661A1 (en) * | 2005-09-26 | 2007-04-05 | The Trustees Of Columbia University In The City Of New York | Side population cells in cardiac repair |
WO2007042771A1 (en) * | 2005-10-10 | 2007-04-19 | Astrazeneca Ab | Three hybrid screening assay using reverse transfected mammalian cell arrays |
US7623624B2 (en) * | 2005-11-22 | 2009-11-24 | Illumina, Inc. | Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction |
US20070161031A1 (en) * | 2005-12-16 | 2007-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Functional arrays for high throughput characterization of gene expression regulatory elements |
US9150882B2 (en) * | 2006-01-31 | 2015-10-06 | The Board Of Trustees Of The Leland Stanford Junior University | Self-complementary parvoviral vectors, and methods for making and using the same |
WO2007106598A2 (en) * | 2006-03-15 | 2007-09-20 | The General Hospital Corporation | Devices and methods for detecting cells and other analytes |
US7700541B2 (en) * | 2006-04-06 | 2010-04-20 | Nitto Denko Corporation | Biodegradable cationic polymers |
US7830575B2 (en) * | 2006-04-10 | 2010-11-09 | Illumina, Inc. | Optical scanner with improved scan time |
US20070248960A1 (en) * | 2006-04-19 | 2007-10-25 | Rees Dianne M | Arrays containing cleavable RNAi molecules |
US20080108513A1 (en) * | 2006-06-01 | 2008-05-08 | Northwestern University | Cellular Arrays |
WO2008121153A2 (en) * | 2006-08-17 | 2008-10-09 | University Of Utah Research Foundation | Dendrimers and methods of making and using thereof |
WO2008036825A2 (en) * | 2006-09-22 | 2008-03-27 | Dharmacon, Inc. | Duplex oligonucleotide complexes and methods for gene silencing by rna interference |
EP2083843A4 (en) * | 2006-09-29 | 2012-11-07 | Univ Utah Res Found | Multifunctional carriers for the delivery of nucleic acids and methods of use thereof |
CN101578520B (en) * | 2006-10-18 | 2015-09-16 | 哈佛学院院长等 | Based on formed pattern porous medium cross flow and through biometric apparatus, and preparation method thereof and using method |
CA2669673A1 (en) * | 2006-11-14 | 2008-05-22 | The Trustees Of The University Of Pennsylvania | Efficient nuclear delivery of antisense oligonucleotides or sirna in vitro and vivo by nano-tranforming polymersomes |
WO2008071430A1 (en) * | 2006-12-13 | 2008-06-19 | Qiagen Gmbh | Transfection microarrays |
WO2008112127A2 (en) * | 2007-03-08 | 2008-09-18 | Switchgear Genomics | Functional arrays for high throughput characterization of regulatory elements in untranslated regions of genes |
JP5024823B2 (en) * | 2007-05-30 | 2012-09-12 | 独立行政法人産業技術総合研究所 | Cell motility evaluation cell chip |
US20080312174A1 (en) * | 2007-06-05 | 2008-12-18 | Nitto Denko Corporation | Water soluble crosslinked polymers |
US8604692B2 (en) * | 2007-11-06 | 2013-12-10 | Translational Therapeutics, Inc. | Mass spectrometry assay for eIF4E and eIF4E regulon activity |
JP5749493B2 (en) | 2007-11-06 | 2015-07-15 | トランスレイショナル セラピューティクス, インコーポレイテッド | Mass spectrometry assay for eIF4E and eIF4E regulon activity |
US8188060B2 (en) | 2008-02-11 | 2012-05-29 | Dharmacon, Inc. | Duplex oligonucleotides with enhanced functionality in gene regulation |
CA2719320A1 (en) | 2008-03-27 | 2009-10-01 | President And Fellows Of Harvard College | Three-dimensional microfluidic devices |
AU2009228014B2 (en) * | 2008-03-27 | 2014-10-02 | President And Fellows Of Harvard College | Cotton thread as a low-cost multi-assay diagnostic platform |
US8921118B2 (en) * | 2008-03-27 | 2014-12-30 | President And Fellows Of Harvard College | Paper-based microfluidic systems |
US9829488B2 (en) * | 2008-03-27 | 2017-11-28 | President And Fellows Of Havard College | Paper-based cellular arrays |
US8715732B2 (en) * | 2009-01-05 | 2014-05-06 | Cornell University | Nucleic acid hydrogel via rolling circle amplification |
ES2612507T3 (en) | 2009-03-06 | 2017-05-17 | President And Fellows Of Harvard College | Microfluidic and electrochemical devices |
WO2010115033A2 (en) * | 2009-04-02 | 2010-10-07 | Regents Of The University Of Minnesota | Nucleotide repeat expansion-associated polypeptides and uses thereof |
US8815779B2 (en) | 2009-09-16 | 2014-08-26 | SwitchGear Genomics, Inc. | Transcription biomarkers of biological responses and methods |
CA2788113A1 (en) | 2010-02-03 | 2011-08-11 | President And Fellows Of Harvard College | Devices and methods for multiplexed assays |
CN101787375B (en) * | 2010-02-10 | 2012-08-22 | 浙江大学 | Reverse non-viral vector gene transfection method |
KR20120006591A (en) * | 2010-07-13 | 2012-01-19 | 삼성전자주식회사 | Sensor for fluid preventing generation of air bubble |
US20120308538A1 (en) * | 2011-05-31 | 2012-12-06 | Ursula Bond | Preventing spoilage in alcohol fermentations |
US9029297B2 (en) | 2011-07-25 | 2015-05-12 | Csir | Array printing |
KR101545826B1 (en) | 2011-07-25 | 2015-08-19 | 씨에스아이알 | Array printing |
US9012375B2 (en) | 2011-07-25 | 2015-04-21 | Csir | Array printing |
SG11201504558TA (en) | 2012-12-11 | 2015-07-30 | Einstein Coll Med | Methods for high throughput receptor:ligand identification |
EP3065711A4 (en) * | 2013-11-05 | 2017-06-21 | Takara Bio USA, Inc. | Dry transfection compositions and methods for making and using the same |
US20150174547A1 (en) * | 2013-12-20 | 2015-06-25 | Neil Emans | Transfection systems, methods and media |
CN106978444B (en) * | 2016-01-15 | 2021-12-17 | 江苏命码生物科技有限公司 | Method for introducing nucleic acid into cell |
CN109689096A (en) | 2016-05-18 | 2019-04-26 | 阿尔伯特爱因斯坦医学院公司 | Variant PD-L1 polypeptide, T cell modulability multimeric polypeptide and its application method |
KR20190019068A (en) | 2016-05-18 | 2019-02-26 | 큐 바이오파마, 인크. | T-cell modulated multimeric polypeptides and methods for their use |
IL266696B2 (en) | 2016-12-22 | 2023-04-01 | Cue Biopharma Inc | T-cell modulatory multimeric polypeptides and methods of use thereof |
WO2018129474A1 (en) | 2017-01-09 | 2018-07-12 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
KR102619015B1 (en) | 2017-03-15 | 2023-12-28 | 큐 바이오파마, 인크. | How to Regulate Your Immune Response |
CN111886241A (en) | 2018-01-09 | 2020-11-03 | 库尔生物制药有限公司 | Multimeric T cell modulating polypeptides and methods of use thereof |
CN116096405A (en) | 2020-05-12 | 2023-05-09 | Cue生物制药股份有限公司 | Multimeric T cell modulating polypeptides and methods of use thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4591567A (en) * | 1982-04-21 | 1986-05-27 | California Institute Of Technology | Recombinant DNA screening system including fixed array replicator and support |
US5750346A (en) * | 1995-08-07 | 1998-05-12 | The Perkin-Elmer Corporation | Host organism capture |
US5811274A (en) * | 1994-12-09 | 1998-09-22 | The Regents Of The University Of Michigan | Methods, compositions and apparatus for cell transfection |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5326691A (en) * | 1991-11-21 | 1994-07-05 | John Hozier | Micro-libraries and methods of making and manipulating them methods for generating and analyzing micro-libraries |
US5457041A (en) * | 1994-03-25 | 1995-10-10 | Science Applications International Corporation | Needle array and method of introducing biological substances into living cells using the needle array |
US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
EP0769063A1 (en) | 1994-06-27 | 1997-04-23 | The Johns Hopkins University | Targeted gene delivery system |
US6103479A (en) * | 1996-05-30 | 2000-08-15 | Cellomics, Inc. | Miniaturized cell array methods and apparatus for cell-based screening |
US5851818A (en) | 1996-05-31 | 1998-12-22 | Sequus Pharmaceuticals, Inc. | Condensed plasmid-liposome complex for transfection |
US6133026A (en) | 1996-05-31 | 2000-10-17 | Sequus Pharmaceuticals, Inc. | Condensed plasmid-liposome complex for transfection |
US6143037A (en) * | 1996-06-12 | 2000-11-07 | The Regents Of The University Of Michigan | Compositions and methods for coating medical devices |
US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
WO1999055886A1 (en) * | 1998-04-24 | 1999-11-04 | Genova Pharmaceuticals Corporation | Function-based gene discovery |
CA2329986A1 (en) | 1998-04-30 | 1999-11-11 | Dolores Cahill | New method for the selection of clones of an expression library involving rearraying |
ATE282717T1 (en) | 1998-04-30 | 2004-12-15 | Max Planck Gesellschaft | NOVEL METHOD FOR IDENTIFYING CLONES WITH A DESIRED BIOLOGICAL PROPERTY, STARTING FROM AN EXPRESSION GENE BANK |
GB9908681D0 (en) | 1999-04-16 | 1999-06-09 | Central Research Lab Ltd | Apparatus for, and method of, introducing a substance into an object |
US6398808B1 (en) * | 1999-06-15 | 2002-06-04 | Scimed Life Systems, Inc. | Localized delivery of genetic information from biostable materials |
DE60031997D1 (en) * | 1999-09-17 | 2007-01-04 | Whitehead Biomedical Inst | UMKEHRTRANSFEKTIONSVERFAHREN |
US20020006664A1 (en) * | 1999-09-17 | 2002-01-17 | Sabatini David M. | Arrayed transfection method and uses related thereto |
US20040132008A1 (en) * | 2002-04-30 | 2004-07-08 | Doranz Benjamin J | Elucidation of gene function |
US6792496B2 (en) * | 2001-08-02 | 2004-09-14 | Intel Corporation | Prefetching data for peripheral component interconnect devices |
-
2001
- 2001-03-22 US US09/817,003 patent/US20020006664A1/en not_active Abandoned
-
2002
- 2002-03-22 CA CA002440378A patent/CA2440378A1/en not_active Abandoned
- 2002-03-22 WO PCT/US2002/009265 patent/WO2002077264A2/en active Application Filing
- 2002-03-22 EP EP02725351A patent/EP1379642A4/en not_active Withdrawn
- 2002-03-22 JP JP2002575306A patent/JP2004530426A/en active Pending
-
2003
- 2003-03-04 US US10/379,130 patent/US6951757B2/en not_active Expired - Lifetime
- 2003-03-28 US US10/403,720 patent/US20030203486A1/en not_active Abandoned
- 2003-03-28 US US10/403,630 patent/US20030228601A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4591567A (en) * | 1982-04-21 | 1986-05-27 | California Institute Of Technology | Recombinant DNA screening system including fixed array replicator and support |
US5811274A (en) * | 1994-12-09 | 1998-09-22 | The Regents Of The University Of Michigan | Methods, compositions and apparatus for cell transfection |
US5750346A (en) * | 1995-08-07 | 1998-05-12 | The Perkin-Elmer Corporation | Host organism capture |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8883988B2 (en) | 1999-03-02 | 2014-11-11 | Life Technologies Corporation | Compositions for use in recombinational cloning of nucleic acids |
US9309520B2 (en) | 2000-08-21 | 2016-04-12 | Life Technologies Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites |
US8945884B2 (en) | 2000-12-11 | 2015-02-03 | Life Technologies Corporation | Methods and compositions for synthesis of nucleic acid molecules using multiplerecognition sites |
US9534252B2 (en) | 2003-12-01 | 2017-01-03 | Life Technologies Corporation | Nucleic acid molecules containing recombination sites and methods of using the same |
Also Published As
Publication number | Publication date |
---|---|
EP1379642A2 (en) | 2004-01-14 |
US20030203486A1 (en) | 2003-10-30 |
WO2002077264A2 (en) | 2002-10-03 |
CA2440378A1 (en) | 2002-10-03 |
US20030228601A1 (en) | 2003-12-11 |
JP2004530426A (en) | 2004-10-07 |
US20020006664A1 (en) | 2002-01-17 |
US20030228694A1 (en) | 2003-12-11 |
US6951757B2 (en) | 2005-10-04 |
EP1379642A4 (en) | 2006-04-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2002077264A3 (en) | Arrayed transfection method and uses related thereto | |
AU2001278783A1 (en) | Method of amplifying nucleic acid | |
AU2002314693A1 (en) | Nucleic acid amplification method | |
AU2002325538A1 (en) | Nucleic acid amplification methods | |
AU2002337030A1 (en) | Method for analyzing nucleic acid sequences and gene expression | |
DE60031997D1 (en) | UMKEHRTRANSFEKTIONSVERFAHREN | |
AU7878301A (en) | Method of amplifying nucleic acid | |
AU2003206095A1 (en) | Methods and means for amplifying nucleic acid | |
WO2001090345A3 (en) | Methods and compositions for enhancing the delivery of a nucleic acid to a cell | |
AU3027699A (en) | Nucleic acid analysis method | |
AU2001276843A1 (en) | Nucleic acid enzyme biosensor for ions | |
AU2002365912A1 (en) | Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection | |
AU2003280603A1 (en) | Method of amplifying nucleic acid | |
AU2002252297A1 (en) | Methods and tools for nucleic acid sequence analysis selection and generation | |
AU2001241674A1 (en) | Variant galactose oxidase, nucleic acid encoding same, and methods of using same | |
AU2002316863A1 (en) | Method for the preferential nucleic acid amplification of selected nucleic acid regions | |
AU2001296027A1 (en) | Method of determining nucleic acid base sequence | |
AU2002244757A1 (en) | Method for specifically detecting, isolating and characterizing cells from body samples by transfecting nucleic acid constructs | |
AU2003294652A1 (en) | Method and reactor for the amplification of dna | |
WO2003076897A3 (en) | Multiplexed analysis of cellular responses using endogenous reporter genes | |
AU1908100A (en) | Isothermal nucleic acid amplification methods | |
AU4934099A (en) | Method for enzymatic amplification of nucleic acid | |
AU2001250858A1 (en) | Methods of preparing amplified nucleic acid molecules | |
AU2003205817A1 (en) | Methods of nucleic acid amplification | |
AU2003234938A1 (en) | Method of identifying nucleic acid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2440378 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002255920 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002575306 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2002725351 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2002725351 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |