WO2002075022A8 - Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration - Google Patents

Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration

Info

Publication number
WO2002075022A8
WO2002075022A8 PCT/US2002/005509 US0205509W WO02075022A8 WO 2002075022 A8 WO2002075022 A8 WO 2002075022A8 US 0205509 W US0205509 W US 0205509W WO 02075022 A8 WO02075022 A8 WO 02075022A8
Authority
WO
WIPO (PCT)
Prior art keywords
neutral red
generation
motive force
reduced
electrochemical methods
Prior art date
Application number
PCT/US2002/005509
Other languages
French (fr)
Other versions
WO2002075022A1 (en
Inventor
Greogry J Zeikus
Hyoun S Shin
Mahendra K Jain
Original Assignee
Michigan Biotech Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michigan Biotech Inst filed Critical Michigan Biotech Inst
Priority to AU2002240480A priority Critical patent/AU2002240480A1/en
Publication of WO2002075022A1 publication Critical patent/WO2002075022A1/en
Publication of WO2002075022A8 publication Critical patent/WO2002075022A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01M—PROCESSES OR MEANS, e.g. BATTERIES, FOR THE DIRECT CONVERSION OF CHEMICAL ENERGY INTO ELECTRICAL ENERGY
    • H01M8/00—Fuel cells; Manufacture thereof
    • H01M8/16—Biochemical fuel cells, i.e. cells in which microorganisms function as catalysts
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/50—Fuel cells

Abstract

Disclosed are methods using neutral red to mediate the interconversion of chemical and elctrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced: oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial cell growth. Neutral red is also able to promote coversation of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.
PCT/US2002/005509 2001-02-26 2002-02-25 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration WO2002075022A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002240480A AU2002240480A1 (en) 2001-02-26 2002-02-25 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/793,025 US6495023B1 (en) 1998-07-09 2001-02-26 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration
US09/793,025 2001-02-26

Publications (2)

Publication Number Publication Date
WO2002075022A1 WO2002075022A1 (en) 2002-09-26
WO2002075022A8 true WO2002075022A8 (en) 2002-11-07

Family

ID=25158852

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/005509 WO2002075022A1 (en) 2001-02-26 2002-02-25 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration

Country Status (3)

Country Link
US (2) US6495023B1 (en)
AU (1) AU2002240480A1 (en)
WO (1) WO2002075022A1 (en)

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Also Published As

Publication number Publication date
US6495023B1 (en) 2002-12-17
US20030138674A1 (en) 2003-07-24
AU2002240480A1 (en) 2002-10-03
WO2002075022A1 (en) 2002-09-26

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