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Publication numberWO2002070029 A3
Publication typeApplication
Application numberPCT/US2002/005827
Publication date6 Feb 2003
Filing date26 Feb 2002
Priority date2 Mar 2001
Also published asCA2439813A1, CA2439813C, CA2659188A1, DE60232061D1, EP1372748A2, EP1372748B1, US6949251, US7357941, US7390498, US8173149, US20030180376, US20050170012, US20060292198, US20090110743, WO2002070029A2
Publication numberPCT/2002/5827, PCT/US/2/005827, PCT/US/2/05827, PCT/US/2002/005827, PCT/US/2002/05827, PCT/US2/005827, PCT/US2/05827, PCT/US2002/005827, PCT/US2002/05827, PCT/US2002005827, PCT/US200205827, PCT/US2005827, PCT/US205827, WO 02070029 A3, WO 02070029A3, WO 2002/070029 A3, WO 2002070029 A3, WO 2002070029A3, WO-A3-02070029, WO-A3-2002070029, WO02070029 A3, WO02070029A3, WO2002/070029A3, WO2002070029 A3, WO2002070029A3
InventorsParesh S Dalal, Godofredo R Dimaano, Carol Ann Toth, Shailesh C Kulkarni
ApplicantStryker Corp, Paresh S Dalal, Godofredo R Dimaano, Carol Ann Toth, Shailesh C Kulkarni
Export CitationBiBTeX, EndNote, RefMan
External Links: Patentscope, Espacenet
Porous beta-tricalcium phosphate granules and methods for producing same
WO 2002070029 A3
Abstract
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 Ám, preferably 50-125 Ám. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implementable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and including bone formation are also provided.
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
WO2001013970A1 *28 Aug 20001 Mar 2001Gerontocare GmbhResorbable bone replacement and bone formation material
GB2323083A * Title not available
US4596574 *14 May 198424 Jun 1986The Regents Of The University Of CaliforniaBiodegradable porous ceramic delivery system for bone morphogenetic protein
US4869906 *17 Apr 198726 Sep 1989Merck Patent Gesellschaft Mit Beschrankter HaftungTricalcium phosphate for implant materials wherein the pores of the tricalciumphosphate are filled with antibiotic and amino acid
US5135394 *29 Aug 19914 Aug 1992Olympus Optical Co., Ltd.Extraction cavity filling member and a manufacturing method thereof
US5422340 *8 Jun 19946 Jun 1995Ammann; Arthur J.TGF-βformulation for inducing bone growth
Referenced by
Citing PatentFiling datePublication dateApplicantTitle
US88709549 Sep 200928 Oct 2014Biomimetic Therapeutics, LlcPlatelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
US91619674 Dec 200920 Oct 2015Biomimetic Therapeutics, LlcCompositions and methods for treating the vertebral column
US954537716 Jul 200717 Jan 2017Biomimetic Therapeutics, LlcPlatelet-derived growth factor compositions and methods of use thereof
Classifications
International ClassificationA61L27/12, C01B25/32, A61L27/00, A61L24/00, A61L27/56, A61K47/04
Cooperative ClassificationA61L27/50, A61L27/12, Y10S530/811, A61L27/56, A61L2430/02
European ClassificationA61L27/50, A61L27/12, A61L27/56
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