WO2002062405A3 - Selective uptake of materials by bone implants - Google Patents

Selective uptake of materials by bone implants Download PDF

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Publication number
WO2002062405A3
WO2002062405A3 PCT/US2002/004980 US0204980W WO02062405A3 WO 2002062405 A3 WO2002062405 A3 WO 2002062405A3 US 0204980 W US0204980 W US 0204980W WO 02062405 A3 WO02062405 A3 WO 02062405A3
Authority
WO
WIPO (PCT)
Prior art keywords
implant
selective uptake
bone
demineralization
machined
Prior art date
Application number
PCT/US2002/004980
Other languages
French (fr)
Other versions
WO2002062405A2 (en
Inventor
Tom Sander
Original Assignee
Regeneration Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneration Tech Inc filed Critical Regeneration Tech Inc
Priority to AU2002252019A priority Critical patent/AU2002252019A1/en
Publication of WO2002062405A2 publication Critical patent/WO2002062405A2/en
Publication of WO2002062405A3 publication Critical patent/WO2002062405A3/en

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    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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Abstract

This invention provides a novel unitary bone implant having at least one rigid, mineralized bone segment, which may be machined to include threads, grooves, a driver head, perforations, a recess or a symmetric or asymmetric shape, and a flexible, demineralized segment, which may also be machined to any desired shape prior to demineralization, or after demineralization. The implant of this invention has wide orthopedic applicability, including but not limited to repair or replacement of ligaments, tendons and joints and for inducing vertebral fusions and fractured bone repair. In a particular embodiment of this invention, selective uptake of biologically active or inactive materials into the segmentally demineralized portion of the implant is disclosed.
PCT/US2002/004980 1997-10-27 2002-02-05 Selective uptake of materials by bone implants WO2002062405A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002252019A AU2002252019A1 (en) 2001-02-05 2002-02-05 Selective uptake of materials by bone implants

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/958,364 US6090998A (en) 1997-10-27 1997-10-27 Segmentally demineralized bone implant
US09/778,046 2001-02-05
US09/778,046 US20010020188A1 (en) 1997-10-27 2001-02-05 Selective uptake of materials by bone implants

Publications (2)

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WO2002062405A2 WO2002062405A2 (en) 2002-08-15
WO2002062405A3 true WO2002062405A3 (en) 2002-12-19

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PCT/US1998/021530 WO1999021515A1 (en) 1997-10-27 1998-10-13 Segmentally demineralized bone implant
PCT/US2002/004980 WO2002062405A2 (en) 1997-10-27 2002-02-05 Selective uptake of materials by bone implants

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US (2) US6090998A (en)
EP (1) EP1027017A1 (en)
JP (1) JP2001520914A (en)
AU (1) AU755050B2 (en)
CA (1) CA2304099A1 (en)
HU (1) HUP0200217A2 (en)
PL (1) PL342109A1 (en)
WO (2) WO1999021515A1 (en)

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