WO2002061428A3 - Method of disrupting interactions between biotin and biotin-binding compounds - Google Patents

Method of disrupting interactions between biotin and biotin-binding compounds Download PDF

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Publication number
WO2002061428A3
WO2002061428A3 PCT/GB2002/000466 GB0200466W WO02061428A3 WO 2002061428 A3 WO2002061428 A3 WO 2002061428A3 GB 0200466 W GB0200466 W GB 0200466W WO 02061428 A3 WO02061428 A3 WO 02061428A3
Authority
WO
WIPO (PCT)
Prior art keywords
biotin
conjugate
compound
binding compounds
disrupted
Prior art date
Application number
PCT/GB2002/000466
Other languages
French (fr)
Other versions
WO2002061428A2 (en
WO2002061428A8 (en
Inventor
Anders Holmberg
Original Assignee
Magnetic Biosolutions Sweden A
Anders Holmberg
Golding Louise
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magnetic Biosolutions Sweden A, Anders Holmberg, Golding Louise filed Critical Magnetic Biosolutions Sweden A
Priority to EP02710163A priority Critical patent/EP1356290B1/en
Priority to US10/470,846 priority patent/US7279285B2/en
Priority to AT02710163T priority patent/ATE553379T1/en
Priority to AU2002228214A priority patent/AU2002228214B2/en
Priority to JP2002561943A priority patent/JP4394879B2/en
Priority to CA2432538A priority patent/CA2432538C/en
Publication of WO2002061428A2 publication Critical patent/WO2002061428A2/en
Publication of WO2002061428A3 publication Critical patent/WO2002061428A3/en
Publication of WO2002061428A8 publication Critical patent/WO2002061428A8/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding

Abstract

The present invention relates to a method of disrupting a conjugate comprising a biotin compound and a biotin-binding compound, said method comprising the step of contacting said conjugate with an effective amount of a substantially aqueous solution under conditions such that the conjugate is disrupted, preferably reversibly disrupted, thereby forming a biotin compound and a biotin-binding compound. In particular, the invention relates to a method of reversibly releasing a biotinylated moiety from a streptavidin ( or avidin) coated support. Uses of the methods in techniques of detection, identification, determination, purification, separation and/or isolation of target proteins or nucleic acid molecules are also encompassed by the present invention.
PCT/GB2002/000466 2001-02-01 2002-02-01 Method of disrupting interactions between biotin and biotin-binding compounds WO2002061428A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP02710163A EP1356290B1 (en) 2001-02-01 2002-02-01 Method of disrupting interactions between biotin and biotin-binding compounds
US10/470,846 US7279285B2 (en) 2001-02-01 2002-02-01 Method of reversibly disrupting a conjugate comprising a biotin compound and a biotin-binding compound
AT02710163T ATE553379T1 (en) 2001-02-01 2002-02-01 METHOD FOR DESTROYING INTERACTIONS BETWEEN BIOTIN AND BIOTIN-BINDING COMPOUNDS
AU2002228214A AU2002228214B2 (en) 2001-02-01 2002-02-01 Method of disrupting interactions between biotin and biotin-binding compounds
JP2002561943A JP4394879B2 (en) 2001-02-01 2002-02-01 Method for reversibly decomposing a complex containing a biotin compound and a compound that binds biotin
CA2432538A CA2432538C (en) 2001-02-01 2002-02-01 Method of disrupting interactions between biotin and biotin-binding compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0102568.3 2001-02-01
GBGB0102568.3A GB0102568D0 (en) 2001-02-01 2001-02-01 Method
US26652401P 2001-02-05 2001-02-05

Publications (3)

Publication Number Publication Date
WO2002061428A2 WO2002061428A2 (en) 2002-08-08
WO2002061428A3 true WO2002061428A3 (en) 2003-04-17
WO2002061428A8 WO2002061428A8 (en) 2003-11-27

Family

ID=9907949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/000466 WO2002061428A2 (en) 2001-02-01 2002-02-01 Method of disrupting interactions between biotin and biotin-binding compounds

Country Status (8)

Country Link
US (1) US7279285B2 (en)
EP (1) EP1356290B1 (en)
JP (1) JP4394879B2 (en)
AT (1) ATE553379T1 (en)
AU (1) AU2002228214B2 (en)
CA (1) CA2432538C (en)
GB (1) GB0102568D0 (en)
WO (1) WO2002061428A2 (en)

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WO2004072258A2 (en) * 2003-02-11 2004-08-26 University Of Washington Stimuli-responsive polymer conjugates and related methods
DE602004018631D1 (en) 2003-04-24 2009-02-05 Afshin Ahmadian EN
EP2112168B1 (en) * 2006-12-28 2014-10-01 Japan Tobacco Inc. Use of thermostable biotin-binding protein
US7981688B2 (en) 2007-03-08 2011-07-19 University Of Washington Stimuli-responsive magnetic nanoparticles and related methods
EP2167965B1 (en) * 2007-06-22 2013-04-10 B.R.A.H.M.S GmbH Method for detecting analytes
DE102007044708A1 (en) * 2007-09-18 2009-03-19 Eads Deutschland Gmbh Apparatus and method for regenerating biosensors
US9090910B2 (en) * 2008-07-16 2015-07-28 Kbi Biopharma, Inc. Methods and systems for manipulating particles using a fluidized bed
KR20100122366A (en) * 2009-05-12 2010-11-22 삼성전자주식회사 Magnetic nanoparticles for nucleic acid sequencing and the method using the same
US8426214B2 (en) * 2009-06-12 2013-04-23 University Of Washington System and method for magnetically concentrating and detecting biomarkers
US20110117668A1 (en) * 2009-11-09 2011-05-19 University Of Washington Through Its Center For Commercialization Self-powered smart diagnostic devices
US9080933B2 (en) 2009-11-09 2015-07-14 University Of Washington Through Its Center For Commercialization Stimuli-responsive polymer diagnostic assay comprising magnetic nanoparticles and capture conjugates
US20110318743A1 (en) * 2010-06-28 2011-12-29 Life Technologies Corporation Methods, workflows, kits, apparatuses, and computer program media for nucleic acid sample preparation for nucleic acid sequencing
WO2012159089A1 (en) * 2011-05-19 2012-11-22 Sequenom, Inc. Products and processes for multiplex nucleic acid identification
ES2873850T3 (en) 2013-08-19 2021-11-04 Abbott Molecular Inc Next Generation Sequencing Libraries
US11225658B2 (en) * 2013-12-05 2022-01-18 New England Biolabs, Inc. Enrichment and sequencing of RNA species
WO2016120247A1 (en) * 2015-01-26 2016-08-04 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Methods for a quantitative release of biotinylated peptides and proteins from streptavidin complexes
AU2016250849A1 (en) 2015-04-24 2017-11-02 Agena Bioscience, Inc. Multiplex methods for detection and quantification of minor variants
US10233489B2 (en) 2015-04-24 2019-03-19 Agena Bioscience, Inc. Multiplexed method for the identification and quantitation of minor alleles and polymorphisms
MA45489A (en) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh CELL CULTURE PROCESSES, ASSOCIATED KITS AND APPARATUS
NZ758485A (en) 2017-04-27 2024-02-23 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
KR102653725B1 (en) 2018-01-29 2024-04-01 세인트 쥬드 칠드런즈 리써치 호스피탈, 인코포레이티드 Methods for Nucleic Acid Amplification
WO2020225971A1 (en) * 2019-05-08 2020-11-12 株式会社日立ハイテク Automatic analysis device pretreatment method
WO2020242856A1 (en) * 2019-05-31 2020-12-03 The Penn State Research Foundation Specific selection of immune cells using versatile display scaffolds
CN111676217B (en) * 2019-09-12 2021-10-26 南京君华基因科技有限公司 Method and system for improving nucleic acid yield and being compatible with subsequent reaction

Citations (6)

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EP0456304A1 (en) * 1990-05-04 1991-11-13 Johnson & Johnson Clinical Diagnostics, Inc. Preparation and isolation of single-stranded biotinylated nucleic acids by avidin-biotin cleavage
JPH0578369A (en) * 1991-08-12 1993-03-30 Mitsubishi Petrochem Co Ltd Method for separating and recovering d-biotin
US5395856A (en) * 1991-05-16 1995-03-07 Rohm And Haas Company HPLC avidin monomer affinity resin
WO1997000329A2 (en) * 1995-06-14 1997-01-03 Yeda Research And Development Co. Ltd. Modified avidin and streptavidin molecules and use thereof
WO2000070073A1 (en) * 1999-05-19 2000-11-23 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
WO2001051067A1 (en) * 2000-01-13 2001-07-19 Baxter International Inc. Multiple inactivated blood factor anticoagulant composition

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US6022688A (en) * 1996-05-13 2000-02-08 Sequenom, Inc. Method for dissociating biotin complexes

Patent Citations (7)

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US5387505A (en) * 1990-05-04 1995-02-07 Eastman Kodak Company Preparation and isolation of single-stranded biotinylated nucleic acids by heat avidin-biotin cleavage
US5395856A (en) * 1991-05-16 1995-03-07 Rohm And Haas Company HPLC avidin monomer affinity resin
JPH0578369A (en) * 1991-08-12 1993-03-30 Mitsubishi Petrochem Co Ltd Method for separating and recovering d-biotin
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Non-Patent Citations (6)

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Title
DATABASE WPI Section Ch Week 199317, Derwent World Patents Index; Class B02, AN 1993-140353, XP002226763 *
DING ZHONGLI ET AL: "Temperature control of biotin binding and release with A streptavidin-poly(N-isopropylacrylamide) site-specific conjugate.", BIOCONJUGATE CHEMISTRY, vol. 10, no. 3, May 1999 (1999-05-01), pages 395 - 400, XP002226760, ISSN: 1043-1802 *
FOULON C F ET AL: "Preparation and Biological Evaluation of an Astatine-211 Labeled Biotin Conjugate: Biotinyl-3-[At]astatoanilide", NUCLEAR MEDICINE AND BIOLOGY, ELSEVIER SCIENCE PUBLISHERS, NEW YORK, NY, US, vol. 24, no. 2, 1 February 1997 (1997-02-01), pages 135 - 143, XP004058584, ISSN: 0969-8051 *
GARRET-FLAUDY F ET AL: "Use of the avidin (imino)biotin system as a general approach to affinity precipitation.", BIOTECHNOLOGY AND BIOENGINEERING. UNITED STATES 2000-2001, vol. 71, no. 3, 2000, pages 223 - 234, XP002226762, ISSN: 0006-3592 *
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Also Published As

Publication number Publication date
JP4394879B2 (en) 2010-01-06
AU2002228214B2 (en) 2007-01-04
EP1356290A2 (en) 2003-10-29
EP1356290B1 (en) 2012-04-11
GB0102568D0 (en) 2001-03-21
CA2432538C (en) 2012-03-20
JP2004527732A (en) 2004-09-09
US20040077024A1 (en) 2004-04-22
WO2002061428A2 (en) 2002-08-08
WO2002061428A8 (en) 2003-11-27
ATE553379T1 (en) 2012-04-15
CA2432538A1 (en) 2002-08-08
US7279285B2 (en) 2007-10-09

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