WO2002048692A1 - Apparatus and method for imaging a histological sample - Google Patents
Apparatus and method for imaging a histological sample Download PDFInfo
- Publication number
- WO2002048692A1 WO2002048692A1 PCT/GB2001/005432 GB0105432W WO0248692A1 WO 2002048692 A1 WO2002048692 A1 WO 2002048692A1 GB 0105432 W GB0105432 W GB 0105432W WO 0248692 A1 WO0248692 A1 WO 0248692A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sample
- autofluorescence
- imaging
- histological
- electromagnetic radiation
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
- G01N21/6458—Fluorescence microscopy
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01270762A EP1350087A1 (en) | 2000-12-13 | 2001-12-11 | Apparatus and method for imaging a histological sample |
AU2002256549A AU2002256549A1 (en) | 2000-12-13 | 2001-12-11 | Apparatus and method for imaging a histological sample |
US10/433,870 US6992760B2 (en) | 2000-12-13 | 2001-12-11 | Apparatus and method for imaging a histological sample |
CA002427345A CA2427345A1 (en) | 2000-12-13 | 2001-12-11 | Apparatus and method for imaging a histological sample |
JP2002549950A JP2004515780A (en) | 2000-12-13 | 2001-12-11 | Apparatus and method for imaging a tissue specimen |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0030310.7 | 2000-12-13 | ||
GBGB0030310.7A GB0030310D0 (en) | 2000-12-13 | 2000-12-13 | Apparatus and method for imaging a histological sample |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002048692A1 true WO2002048692A1 (en) | 2002-06-20 |
Family
ID=9904943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2001/005432 WO2002048692A1 (en) | 2000-12-13 | 2001-12-11 | Apparatus and method for imaging a histological sample |
Country Status (7)
Country | Link |
---|---|
US (1) | US6992760B2 (en) |
EP (1) | EP1350087A1 (en) |
JP (1) | JP2004515780A (en) |
AU (1) | AU2002256549A1 (en) |
CA (1) | CA2427345A1 (en) |
GB (1) | GB0030310D0 (en) |
WO (1) | WO2002048692A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010138063A1 (en) * | 2009-05-29 | 2010-12-02 | General Electric Company | Method and apparatus for ultraviolet scan planning |
US11906723B2 (en) | 2018-11-01 | 2024-02-20 | Hust-Suzhou Institute For Brainsmatics | High-throughput optical sectioning three-dimensional imaging system |
US11940359B2 (en) | 2017-07-27 | 2024-03-26 | Agilent Technologies, Inc. | Preparation of tissue sections using fluorescence-based detection |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102004022484B4 (en) * | 2004-05-07 | 2007-12-20 | P.A.L.M. Microlaser Technologies Ag | microscope stage |
DE102004023262B8 (en) * | 2004-05-11 | 2013-01-17 | Carl Zeiss Microimaging Gmbh | Method for processing a mass by means of laser irradiation and control system |
DE102005042367B4 (en) * | 2005-09-07 | 2009-11-12 | Leica Microsystems Cms Gmbh | Apparatus for generating 3-D images of a sample |
US7831075B2 (en) * | 2005-10-20 | 2010-11-09 | Case Western Reserve University | Imaging system |
EP1801593A1 (en) | 2005-12-22 | 2007-06-27 | Koninklijke Philips Electronics N.V. | A method of imaging biological specimens using inorganic nanoparticles as label agents |
US7560689B2 (en) * | 2006-03-10 | 2009-07-14 | Canon Kabushiki Kaisha | High-sensitivity mass spectrometer and method |
US9008378B2 (en) * | 2006-12-20 | 2015-04-14 | The Board Of Trustees Of The Leland Stanford Junior University | Arrangement and imaging of biological samples |
US20100000383A1 (en) * | 2007-08-07 | 2010-01-07 | Koos David S | Microscope coupled tissue sectioning system |
JP5141816B2 (en) * | 2009-03-31 | 2013-02-13 | 株式会社島津製作所 | Mass spectrometer |
CN104831377A (en) * | 2009-06-25 | 2015-08-12 | 路博润高级材料公司 | High Strength Fabrics Consisting Of Thin Gauge Constant Compression Elastic Fibers |
US8704176B2 (en) * | 2011-08-10 | 2014-04-22 | Fei Company | Charged particle microscope providing depth-resolved imagery |
US10378135B2 (en) * | 2013-08-06 | 2019-08-13 | Johns Manville | Glass fibre mat and products containing glass fibre mats |
CN106461515B (en) * | 2014-05-12 | 2019-12-03 | 美国政府(由卫生和人类服务部的部长所代表) | Miniature serial segmentation slicer for the imaging of block face |
US9799113B2 (en) | 2015-05-21 | 2017-10-24 | Invicro Llc | Multi-spectral three dimensional imaging system and method |
JP7231345B2 (en) * | 2017-07-27 | 2023-03-01 | アジレント・テクノロジーズ・インク | Preparation of tissue sections using fluorescence-based detection |
DE102017128491B4 (en) * | 2017-11-30 | 2022-12-22 | Leica Biosystems Nussloch Gmbh | Microtome and method of positioning a microtome specimen head |
AU2021424678A1 (en) * | 2021-02-01 | 2023-08-31 | Agilent Technologies, Inc. | Analysis of embedded tissue samples using fluorescence-based detection |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998040007A1 (en) * | 1997-03-13 | 1998-09-17 | Biomax Technologies, Inc. | Methods and apparatus for detecting the rejection of transplanted tissue |
WO1999037204A1 (en) * | 1998-01-26 | 1999-07-29 | Massachusetts Institute Of Technology | Fluorescence imaging endoscope |
WO1999045838A1 (en) * | 1998-03-09 | 1999-09-16 | Spectrascience, Inc. | Optical biopsy system and methods for tissue diagnosis |
WO1999065394A1 (en) * | 1998-06-16 | 1999-12-23 | Bhaskar Banerjee | Detection of cancer using cellular autofluorescence |
WO2000064342A1 (en) * | 1999-04-26 | 2000-11-02 | Contec Medical Inc. | Method and apparatus for diseased tissue diagnosis |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4497792A (en) * | 1981-12-18 | 1985-02-05 | Sherwood Medical Company | Specimen embedding composition |
US4960330A (en) * | 1985-07-16 | 1990-10-02 | Kerschmann Russell L | Image recording apparatus |
US5682244A (en) * | 1994-03-25 | 1997-10-28 | Barlow; Clyde H. | Automated optical detection of tissue perfusion by microspheres |
US6372512B1 (en) * | 1998-09-16 | 2002-04-16 | Resolution Sciences Corporation | Combined en bloc staining and embedding process |
-
2000
- 2000-12-13 GB GBGB0030310.7A patent/GB0030310D0/en not_active Ceased
-
2001
- 2001-12-11 AU AU2002256549A patent/AU2002256549A1/en not_active Abandoned
- 2001-12-11 WO PCT/GB2001/005432 patent/WO2002048692A1/en not_active Application Discontinuation
- 2001-12-11 JP JP2002549950A patent/JP2004515780A/en not_active Withdrawn
- 2001-12-11 US US10/433,870 patent/US6992760B2/en not_active Expired - Fee Related
- 2001-12-11 EP EP01270762A patent/EP1350087A1/en not_active Withdrawn
- 2001-12-11 CA CA002427345A patent/CA2427345A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998040007A1 (en) * | 1997-03-13 | 1998-09-17 | Biomax Technologies, Inc. | Methods and apparatus for detecting the rejection of transplanted tissue |
WO1999037204A1 (en) * | 1998-01-26 | 1999-07-29 | Massachusetts Institute Of Technology | Fluorescence imaging endoscope |
WO1999045838A1 (en) * | 1998-03-09 | 1999-09-16 | Spectrascience, Inc. | Optical biopsy system and methods for tissue diagnosis |
WO1999065394A1 (en) * | 1998-06-16 | 1999-12-23 | Bhaskar Banerjee | Detection of cancer using cellular autofluorescence |
WO2000064342A1 (en) * | 1999-04-26 | 2000-11-02 | Contec Medical Inc. | Method and apparatus for diseased tissue diagnosis |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010138063A1 (en) * | 2009-05-29 | 2010-12-02 | General Electric Company | Method and apparatus for ultraviolet scan planning |
US8063385B2 (en) | 2009-05-29 | 2011-11-22 | General Electric Company | Method and apparatus for ultraviolet scan planning |
EP2435873A1 (en) * | 2009-05-29 | 2012-04-04 | General Electric Company | Method and apparatus for ultraviolet scan planning |
CN102449529A (en) * | 2009-05-29 | 2012-05-09 | 通用电气公司 | Method and apparatus for ultraviolet scan planning |
EP2435873A4 (en) * | 2009-05-29 | 2012-10-17 | Gen Electric | Method and apparatus for ultraviolet scan planning |
CN102449529B (en) * | 2009-05-29 | 2014-08-20 | 通用电气公司 | Method and apparatus for ultraviolet scan planning |
US11940359B2 (en) | 2017-07-27 | 2024-03-26 | Agilent Technologies, Inc. | Preparation of tissue sections using fluorescence-based detection |
US11906723B2 (en) | 2018-11-01 | 2024-02-20 | Hust-Suzhou Institute For Brainsmatics | High-throughput optical sectioning three-dimensional imaging system |
Also Published As
Publication number | Publication date |
---|---|
US6992760B2 (en) | 2006-01-31 |
CA2427345A1 (en) | 2002-06-20 |
AU2002256549A1 (en) | 2002-06-24 |
JP2004515780A (en) | 2004-05-27 |
US20040026630A1 (en) | 2004-02-12 |
GB0030310D0 (en) | 2001-01-24 |
EP1350087A1 (en) | 2003-10-08 |
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