WO2002047638A1 - Oral bleaching composition - Google Patents
Oral bleaching composition Download PDFInfo
- Publication number
- WO2002047638A1 WO2002047638A1 PCT/EP2001/013829 EP0113829W WO0247638A1 WO 2002047638 A1 WO2002047638 A1 WO 2002047638A1 EP 0113829 W EP0113829 W EP 0113829W WO 0247638 A1 WO0247638 A1 WO 0247638A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tooth cleaning
- oral
- peracid
- cleaning composition
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/38—Percompounds, e.g. peracids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
Definitions
- the present invention relates to an oral composition with an improved teeth whitening effect . More particularly, it relates to an oral composition with an improved teeth whitening effect comprising a safe and effective amount of certain organic peroxyacids.
- WO 96/05802 teaches an oral care composition for whitening teeth.
- the activity is achieved by inclusion in the oral care compositions of certain organic peroxy acids as teeth whitening/bleaching agents, particularly peroxyamidophthalamides and cationic peroxycarboxylic acids such as N-phthalimido per hexanoic acid and quaternary benzylperoxyacid.
- peracids in a whitening/bleaching agent for use on teeth would be an advantage .
- the present invention provides an oral tooth cleaning composition according to claim 1.
- the peracid as used obviously need be acceptable to the subject being treated and to regulatory authorities. Such acceptability will be evident to one skilled in the art.
- the rigours of any regulatory authority will depend upon the jurisdiction and the mammal being treated. Obviously, a higher standard is set for human treatment.
- the term "acceptable for physical contact” need be construed within the spirit of the teachings as found herein.
- the peracid for use in the composion is a peroxy amido phthalamide having the following formula:
- a most preferred peracid is N,N- phthaloylaminoperoxycaproic acid (PAP) .
- the peracid is present in the composition at an amount ranging from 0.01 to 5% by weight, more preferably from 0.05 to 4%, especially from 0.1 to 2% and most preferably from 0.5 to 1.5% by weight of the composition.
- Certain oral bleaching formulations used under medical supervision may contain up to 35% of hydrogen peroxide. It is within the scope of the present invention for the composition as defined to contain such a high level of hydrogen peroxide in conjunction with a peracid. Preferably, the peroxide source is present in an amount ranging from 0.05 to 4%, more preferably from 0.1 to 2% by weight of the composition.
- the peroxide source is preferably hydrogen peroxide but may also be another source suitable for use in oral care compositions e.g. Carbonide peroxide.
- the present invention extends to the use of the composition for the whitening/bleaching/cleaning of teeth.
- the present invention also extends to a commercial package comprising a cleaning composition of the present invention, together with instructions for its use.
- the present invention may also be extended to the cleaning of dentures .
- the oral composition according to the invention may also comprise further ingredients which are common in the art, such as:
- antimicrobial agents e.g. Triclosan, chlorhexidine, copper-, zinc- and stannous salts such as zinc citrate, zinc sulphate, zinc glycinate, sodium zinc citrate and stannous pyrophosphate , sanguinarine extract, metronidazole, quaternary ammonium compounds, such as cetylpyridinium chloride; bis-guanides, such as chlorhexidine digluconate, hexetidine, octenidine, alexidine; and halogenated bisphenolic compounds, such as 2,2' methylenebis- (4-chloro- 6-bromophenol) ; anti-inflammatory agents such as ibuprofen, flurbiprofen, aspirin, indomethacin etc . ,-
- anti-caries agents such as sodium- and stannous fluoride, aminefluorides, sodium monofluorophosphate, sodium trimeta phosphate and casein;
- plaque buffers such as urea, calcium lactate, calcium glycerophosphate and strontium polyacrylates
- vitamins such as Vitamins A, C and E;
- desensitising agents e.g. potassium citrate, potassium chloride, potassium tartrate, potassium bicarbonate, potassium oxalate, potassium nitrate and strontium salts;
- anti-calculus agents e.g. alkali-metal pyrophosphates , hypophosphite-containing polymers, organic phosphonates and phosphocitrates etc . ;
- biomolecules e.g. bacteriocins , antibodies, enzymes, etc.;
- flavours e.g. peppermint and spearmint oils
- proteinaceous materials such as collagen; Keratin;
- opacifying agents opacifying agents; colouring agents;
- pharmaceutically acceptable carriers e.g. starch, sucrose, water or water/alcohol systems etc.;
- surfactants such as anionic, nonionic, cationic and zwitterionic or amphoteric surfactants
- particulate abrasive materials such as silicas, aluminas, calcium carbonates, dicalciumphosphates,. calcium pyrophosphates, hydroxyapatites, trimetaphosphates, insoluble hexametaphosphates and so on, including agglomerated particulate abrasive materials, usually in amounts between 3 and 60% by weight of the oral care composition.
- humectants such as glycerol , sorbitol, propyleneglycol, xylitol, lactitol etc.;
- binders and thickeners such as sodium carboxymethyl- cellulose, xanthan gum, gum arabic etc. as well as synthetic polymers such as polyacrylates and carboxyvinyl polymers such as Carbopol ® ;
- polymeric compounds which can enhance the delivery of active ingredients such as antimicrobial agents can also be included.
- examples of such polymers are copolymers of polyvinylmethylether with maleic anhydride and other similar delivery enhancing polymers, e.g. those described in DE-A-3,942,643 (Colgate);
- bleaching agents such as peroxy compounds e.g. potassium peroxydiphosphate, effervescing systems such as sodium bicarbonate/citric acid systems, colour change systems, and so on.
- Liposomes may also be used to improve delivery or stability of active ingredients.
- the oral compositions may be in any form common in the art, e.g. toothpaste, gel, mousse, bioadhesive patch/strip, aerosol, gum, lozenge, tooth lacquers, mouthwash, powder, cream, etc. and may also be formulated into systems for use in dual-compartment type dispensers.
- the bleaching agents were evaluated as follows:
- Synthetic hydroxyapatite discs were polished and placed in sterile saliva at 37°C overnight to form a pellicle.
- Table 1 shows the use of PAP alone in an aqueous 0.5 M NaHC03 solution together with 0.1 % H202.
- Table 1 shows that the addition of a hydrogen peroxide to the peracid provides a more effective bleaching composition over PAP alone.
- Table 2 shows data from a PAP bleaching experiment in which commercial products were used to make formulations.
- Eureco HCP-11 is a commercial formulation containing a PAP/cyclodextrin complex material .
- Eureco HCL-17 is a commercial formulation containing an aqueous dispersion of PAP.
- the aformentioned commercial formulations are available from available from Ausimont : Via S. Pietro, 50/A 1-20021 Bollate, Milano, Italy.
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0303048A HUP0303048A2 (en) | 2000-12-15 | 2001-11-26 | Oral bleaching composition, its use and packaged product containing such composition |
AU2002216059A AU2002216059A1 (en) | 2000-12-15 | 2001-11-26 | Oral bleaching composition |
PL362435A PL203249B1 (en) | 2000-12-15 | 2001-11-26 | Oral bleaching composition |
BR0116674-3A BR0116674A (en) | 2000-12-15 | 2001-11-26 | Oral tooth cleaning composition, use of oral tooth cleaning composition and commercial packaging |
EP01270310A EP1341513B1 (en) | 2000-12-15 | 2001-11-26 | Oral bleaching composition |
DE60119973T DE60119973T2 (en) | 2000-12-15 | 2001-11-26 | COMPOSITION FOR BLEACHING TEETH |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00311230.7 | 2000-12-15 | ||
EP00311230 | 2000-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2002047638A1 true WO2002047638A1 (en) | 2002-06-20 |
Family
ID=8173449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2001/013829 WO2002047638A1 (en) | 2000-12-15 | 2001-11-26 | Oral bleaching composition |
Country Status (13)
Country | Link |
---|---|
US (1) | US6475472B2 (en) |
EP (1) | EP1341513B1 (en) |
CN (1) | CN1262265C (en) |
AR (1) | AR031813A1 (en) |
AT (1) | ATE326944T1 (en) |
AU (1) | AU2002216059A1 (en) |
BR (1) | BR0116674A (en) |
DE (1) | DE60119973T2 (en) |
ES (1) | ES2263547T3 (en) |
HU (1) | HUP0303048A2 (en) |
PL (1) | PL203249B1 (en) |
WO (1) | WO2002047638A1 (en) |
ZA (1) | ZA200303682B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1656031A2 (en) * | 2003-07-11 | 2006-05-17 | Cadbury Adams USA LLC | Chewing gum and confectionery compositions containing a strain removing complex, and methods of making and using the same |
FR2940121A1 (en) * | 2008-12-23 | 2010-06-25 | Oreal | Composition for the care of greasy skin, especially for eliminating bacteria responsible for acne, contains a combination of phthalamidoperhexanoic acid and zinc salicylate |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8652446B2 (en) | 2000-03-17 | 2014-02-18 | Lg Household & Healthcare Ltd. | Apparatus and method for whitening teeth |
ES2320321T3 (en) | 2000-03-17 | 2009-05-21 | LG HOUSEHOLD & HEALTH CARE LTD. | PATCHES FOR WHITENING TEETH. |
US7785572B2 (en) | 2000-03-17 | 2010-08-31 | Lg Household And Health Care Ltd. | Method and device for teeth whitening using a dry type adhesive |
US6689344B2 (en) | 2000-03-17 | 2004-02-10 | Lg Household & Healthcare Ltd. | Patches for teeth whitening |
US6916463B2 (en) * | 2002-09-24 | 2005-07-12 | The Procter & Gamble Company | Oral products having an aesthetic layer |
US20070098648A1 (en) * | 2002-11-05 | 2007-05-03 | Haley Jeffrey T | Treating mouth sores caused by dental braces with blobs of hydrophilic gums |
US8734421B2 (en) | 2003-06-30 | 2014-05-27 | Johnson & Johnson Consumer Companies, Inc. | Methods of treating pores on the skin with electricity |
PT1664935E (en) * | 2003-08-19 | 2008-01-10 | Mallinckrodt Baker Inc | Stripping and cleaning compositions for microelectronics |
US20060045854A1 (en) * | 2004-08-27 | 2006-03-02 | Lynette Zaidel | Oral care composition with cross-linked polymer peroxide |
US9358193B2 (en) * | 2005-02-15 | 2016-06-07 | Martin S. Giniger | Whitening compositions and methods involving nitrogen oxide radicals |
US20070243238A1 (en) * | 2006-04-13 | 2007-10-18 | Haley Jeffrey T | Treating mouth sores with patches adhered to teeth |
US20080187563A1 (en) * | 2006-11-07 | 2008-08-07 | Ehud Levy | Oxygen delivery compositon |
JP5467996B2 (en) * | 2007-04-04 | 2014-04-09 | ヘンケル・アクチェンゲゼルシャフト・ウント・コムパニー・コマンディットゲゼルシャフト・アウフ・アクチェン | Detergent or detergent containing bleach |
US20120089232A1 (en) | 2009-03-27 | 2012-04-12 | Jennifer Hagyoung Kang Choi | Medical devices with galvanic particulates |
CN101843563B (en) * | 2010-05-11 | 2012-06-27 | 李少君 | Whitening toothpaste composite |
CN106726702A (en) * | 2017-03-13 | 2017-05-31 | 广州欧诺洁个人护理用品有限公司 | A kind of tooth whitening products without hydrogen peroxide |
WO2018224311A1 (en) | 2017-06-06 | 2018-12-13 | Unilever N.V. | A composition, method and kit for whitening teeth |
US11110047B2 (en) | 2017-08-07 | 2021-09-07 | Colgate-Palmolive Company | Oral care compositions including cyclic anhydrides |
WO2020001864A1 (en) | 2018-06-26 | 2020-01-02 | Unilever N.V. | A novel polymer, a composition, a method and a kit for whitening teeth |
WO2021094156A1 (en) | 2019-11-11 | 2021-05-20 | Unilever Ip Holdings B.V. | A film and a kit for whitening teeth |
CN113476333A (en) * | 2020-08-19 | 2021-10-08 | 唯艺科学研究(深圳)有限公司 | PAP-containing gel |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0545594A1 (en) * | 1991-11-22 | 1993-06-09 | Colgate-Palmolive Company | Oral composition having improved tooth whitening effect |
GB2290234A (en) * | 1994-06-07 | 1995-12-20 | Janina International | Oral care compositions |
WO1996005802A2 (en) * | 1994-08-22 | 1996-02-29 | Unilever N.V. | Teeth whitening composition containing organic peroxyacids |
US5616335A (en) * | 1993-05-05 | 1997-04-01 | Chemoxal S.A. | Stable thickened disinfecting aqueous composition containing an organic peroxy acid intended for human or animal use |
US5785957A (en) * | 1995-12-12 | 1998-07-28 | Losee; Paul | Inclusion of tooth whitening oxidation chemistries into a tooth-paste composition |
EP0895777A2 (en) * | 1997-08-05 | 1999-02-10 | Ausimont S.p.A. | Compositions based on peroxyacids |
WO2000059461A1 (en) * | 1999-04-01 | 2000-10-12 | Unilever N.V. | Oral composition with an improved teeth whitening effect |
US6136297A (en) * | 1997-06-06 | 2000-10-24 | The Procter & Gamble Company | Delivery system for an oral care substance using a strip of material having low flexural stiffness |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5188821A (en) | 1987-01-30 | 1993-02-23 | Colgate-Palmolive Company | Antibacterial antiplaque oral composition mouthwash or liquid dentifrice |
SE507731C2 (en) | 1988-12-29 | 1998-07-06 | Colgate Palmolive Co | Antibacterial oral antiplaque composition |
US5360569A (en) * | 1993-11-12 | 1994-11-01 | Lever Brothers Company, Division Of Conopco, Inc. | Activation of bleach precursors with catalytic imine quaternary salts |
US5360568A (en) * | 1993-11-12 | 1994-11-01 | Lever Brothers Company, Division Of Conopco, Inc. | Imine quaternary salts as bleach catalysts |
US5370826A (en) * | 1993-11-12 | 1994-12-06 | Lever Brothers Company, Division Of Conopco, Inc. | Quaternay oxaziridinium salts as bleaching compounds |
US5693603A (en) * | 1996-04-30 | 1997-12-02 | Lever Brothers Company, Division Of Conopco, Inc. | Sulfanimines as bleach catalysts |
US5652207A (en) * | 1996-08-12 | 1997-07-29 | Lever Brothers Company, Division Of Conopco, Inc. | Phosphinoyl imines for use as oxygen transfer agents |
US5858949A (en) * | 1996-08-23 | 1999-01-12 | Lever Brothers Company, Division Of Conopco, Inc. | N-acylimines as bleach catalysts |
US5760222A (en) * | 1996-12-03 | 1998-06-02 | Lever Brothers Company, Division Of Conopco, Inc. | Thiadiazole dioxide derived oxaziridines as bleaching compounds |
US5753599A (en) * | 1996-12-03 | 1998-05-19 | Lever Brothers Company, Division Of Conopco, Inc. | Thiadiazole dioxides as bleach enhancers |
US5955415A (en) * | 1997-08-04 | 1999-09-21 | Lever Brothers Company, Division Of Conopco, Inc. | Detergent compositions containing polyethyleneimines for enhanced peroxygen bleach stability |
US6185448B1 (en) * | 1998-09-29 | 2001-02-06 | Simcha Borovsky | Apparatus and method for locating and mapping a catheter in intracardiac operations |
IT1311889B1 (en) * | 1999-03-12 | 2002-03-20 | Farmaceutici Dott Ciccarelli S | TOOTHPASTE PASTE. |
-
2001
- 2001-11-26 ES ES01270310T patent/ES2263547T3/en not_active Expired - Lifetime
- 2001-11-26 DE DE60119973T patent/DE60119973T2/en not_active Expired - Lifetime
- 2001-11-26 WO PCT/EP2001/013829 patent/WO2002047638A1/en active IP Right Grant
- 2001-11-26 ZA ZA200303682A patent/ZA200303682B/en unknown
- 2001-11-26 AT AT01270310T patent/ATE326944T1/en not_active IP Right Cessation
- 2001-11-26 BR BR0116674-3A patent/BR0116674A/en not_active IP Right Cessation
- 2001-11-26 PL PL362435A patent/PL203249B1/en not_active IP Right Cessation
- 2001-11-26 HU HU0303048A patent/HUP0303048A2/en unknown
- 2001-11-26 CN CNB018205364A patent/CN1262265C/en not_active Expired - Fee Related
- 2001-11-26 EP EP01270310A patent/EP1341513B1/en not_active Expired - Lifetime
- 2001-11-26 AU AU2002216059A patent/AU2002216059A1/en not_active Abandoned
- 2001-12-11 US US10/013,602 patent/US6475472B2/en not_active Expired - Fee Related
- 2001-12-14 AR ARP010105805A patent/AR031813A1/en not_active Application Discontinuation
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0545594A1 (en) * | 1991-11-22 | 1993-06-09 | Colgate-Palmolive Company | Oral composition having improved tooth whitening effect |
US5616335A (en) * | 1993-05-05 | 1997-04-01 | Chemoxal S.A. | Stable thickened disinfecting aqueous composition containing an organic peroxy acid intended for human or animal use |
GB2290234A (en) * | 1994-06-07 | 1995-12-20 | Janina International | Oral care compositions |
WO1996005802A2 (en) * | 1994-08-22 | 1996-02-29 | Unilever N.V. | Teeth whitening composition containing organic peroxyacids |
US5785957A (en) * | 1995-12-12 | 1998-07-28 | Losee; Paul | Inclusion of tooth whitening oxidation chemistries into a tooth-paste composition |
US6136297A (en) * | 1997-06-06 | 2000-10-24 | The Procter & Gamble Company | Delivery system for an oral care substance using a strip of material having low flexural stiffness |
EP0895777A2 (en) * | 1997-08-05 | 1999-02-10 | Ausimont S.p.A. | Compositions based on peroxyacids |
WO2000059461A1 (en) * | 1999-04-01 | 2000-10-12 | Unilever N.V. | Oral composition with an improved teeth whitening effect |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1656031A2 (en) * | 2003-07-11 | 2006-05-17 | Cadbury Adams USA LLC | Chewing gum and confectionery compositions containing a strain removing complex, and methods of making and using the same |
EP1656031A4 (en) * | 2003-07-11 | 2011-02-09 | Cadbury Adams Usa Llc | Chewing gum and confectionery compositions containing a strain removing complex, and methods of making and using the same |
FR2940121A1 (en) * | 2008-12-23 | 2010-06-25 | Oreal | Composition for the care of greasy skin, especially for eliminating bacteria responsible for acne, contains a combination of phthalamidoperhexanoic acid and zinc salicylate |
Also Published As
Publication number | Publication date |
---|---|
DE60119973D1 (en) | 2006-06-29 |
HUP0303048A2 (en) | 2003-12-29 |
US6475472B2 (en) | 2002-11-05 |
ZA200303682B (en) | 2006-06-28 |
PL203249B1 (en) | 2009-09-30 |
DE60119973T2 (en) | 2006-09-28 |
BR0116674A (en) | 2003-11-04 |
CN1262265C (en) | 2006-07-05 |
AU2002216059A1 (en) | 2002-06-24 |
US20020122776A1 (en) | 2002-09-05 |
EP1341513A1 (en) | 2003-09-10 |
AR031813A1 (en) | 2003-10-01 |
ES2263547T3 (en) | 2006-12-16 |
CN1481232A (en) | 2004-03-10 |
ATE326944T1 (en) | 2006-06-15 |
PL362435A1 (en) | 2004-11-02 |
EP1341513B1 (en) | 2006-05-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US6475472B2 (en) | Oral bleaching composition | |
EP1351658B1 (en) | Oral composition | |
US5747004A (en) | Self-heating dentifrice | |
EP1115373B1 (en) | Oral composition with an improved teeth whitening effect | |
EP1155681B1 (en) | Oral composition with teeth whitening effect | |
US6165448A (en) | Oral composition with an improved teeth whitening effect | |
US20030068283A1 (en) | Composition | |
US20030215403A1 (en) | Oral composition | |
EP3952829B1 (en) | Process for producing an oral care composition comprising gingerdiol | |
EP3955884B1 (en) | A personal care composition comprising piperlongumine and process for producing the composition | |
US20030068282A1 (en) | Composition | |
EP3955883B1 (en) | A personal care composition comprising tetramethylcurcumin and process for producing the composition | |
US6436372B2 (en) | Oral composition with abrasive mixture of chalk and carbide | |
WO2003020230A1 (en) | Oral composition | |
WO2006005420A1 (en) | Tooth whitening composition |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 1200300511 Country of ref document: VN |
|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2003/03682 Country of ref document: ZA Ref document number: 200303682 Country of ref document: ZA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2001270310 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 594/MUMNP/2003 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 018205364 Country of ref document: CN |
|
WWP | Wipo information: published in national office |
Ref document number: 2001270310 Country of ref document: EP |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
NENP | Non-entry into the national phase |
Ref country code: JP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: JP |
|
WWG | Wipo information: grant in national office |
Ref document number: 2001270310 Country of ref document: EP |