WO2002047609A3 - Feedback control of ultrafiltration to prevent hypotension using osmotic pressure - Google Patents

Feedback control of ultrafiltration to prevent hypotension using osmotic pressure Download PDF

Info

Publication number
WO2002047609A3
WO2002047609A3 PCT/US2001/043334 US0143334W WO0247609A3 WO 2002047609 A3 WO2002047609 A3 WO 2002047609A3 US 0143334 W US0143334 W US 0143334W WO 0247609 A3 WO0247609 A3 WO 0247609A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood
osmotic pressure
patient
filter
ultrafiltration
Prior art date
Application number
PCT/US2001/043334
Other languages
French (fr)
Other versions
WO2002047609A9 (en
WO2002047609A2 (en
Inventor
Mark Gelfoand
John J O'mahony
Howard R Levin
Original Assignee
Chf Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chf Solutions Inc filed Critical Chf Solutions Inc
Priority to AU2002243218A priority Critical patent/AU2002243218A1/en
Publication of WO2002047609A2 publication Critical patent/WO2002047609A2/en
Publication of WO2002047609A9 publication Critical patent/WO2002047609A9/en
Publication of WO2002047609A3 publication Critical patent/WO2002047609A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601—Control or regulation
    • A61M1/1603—Regulation parameters
    • A61M1/1611—Weight of the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3403—Regulation parameters
    • A61M1/341—Regulation parameters by measuring the filtrate rate or volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/367—Circuit parts not covered by the preceding subgroups of group A61M1/3621
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3639—Blood pressure control, pressure transducers specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3344—Measuring or controlling pressure at the body treatment site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3375—Acoustical, e.g. ultrasonic, measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics

Abstract

A method and system for the extracorporeal treatment of blood to remove fluid from the fluid overloaded patient is disclosed that non-invasively measures osmotic pressure across a filter membrane of a blood filter (111). The filter is permeable to water and electrolytes, but not to blood protein. The osmotic pressure indicates the protein concentration in the blood. Osmotic pressure is used to detect when hypotension is about to occur in a patient, as a result of excessive blood volume reduction during treatment of the blood. Using the osmotic pressure measurement as a feedback signal, the rate of fluid extraction is automatically controlled to achieve the desired clinical outcome and avoid precipitating a hypotensive crisis in the patient.
PCT/US2001/043334 2000-11-27 2001-11-21 Feedback control of ultrafiltration to prevent hypotension using osmotic pressure WO2002047609A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002243218A AU2002243218A1 (en) 2000-11-27 2001-11-21 Feedback control of ultrafiltration to prevent hypotension using osmotic pressure

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/721,778 US6689083B1 (en) 2000-11-27 2000-11-27 Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood
US09/721,778 2000-11-27

Publications (3)

Publication Number Publication Date
WO2002047609A2 WO2002047609A2 (en) 2002-06-20
WO2002047609A9 WO2002047609A9 (en) 2003-02-06
WO2002047609A3 true WO2002047609A3 (en) 2003-04-17

Family

ID=24899271

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/043334 WO2002047609A2 (en) 2000-11-27 2001-11-21 Feedback control of ultrafiltration to prevent hypotension using osmotic pressure

Country Status (3)

Country Link
US (3) US6689083B1 (en)
AU (1) AU2002243218A1 (en)
WO (1) WO2002047609A2 (en)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689083B1 (en) * 2000-11-27 2004-02-10 Chf Solutions, Inc. Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood
CA2456091A1 (en) * 2001-08-01 2003-02-13 Jms Co., Ltd. Blood purification apparatus for elevating purification efficiency
US6942633B2 (en) 2002-03-22 2005-09-13 Twin Star Medical, Inc. System for treating tissue swelling
US6890157B2 (en) * 2003-02-05 2005-05-10 Delphi Technologies, Inc. Matching or not matching flow rates in two fluidly-unconnected flow paths
US7125186B1 (en) 2003-08-15 2006-10-24 Thomas Richard Stokes Writing instrument with enclosing structure
JP4394916B2 (en) * 2003-09-19 2010-01-06 独立行政法人科学技術振興機構 Artificial lipid bilayer membrane formation apparatus, artificial lipid bilayer membrane formation method, and use thereof
US7135008B2 (en) * 2003-12-02 2006-11-14 Chf Solutions, Inc. Method and apparatus for ultrafiltration utilizing a peripheral access dual lumen venous cannula
US20050192558A1 (en) * 2004-02-27 2005-09-01 Chf Solutions, Inc. Peripheral access venous cannula with infusion side holes and embedded reinforcement
ES2311895T3 (en) * 2004-03-15 2009-02-16 F. Hoffmann-La Roche Ag THE USE OF BNP TYPE PEPTIDES AND ANF TYPE PEPTIDES TO ASSESS THE RISK OF PADDING A CARDIO-VASCULAR COMPLICATION AS A FREQUENCY OF OVERLOADING THE VOLUME.
WO2006006163A2 (en) * 2004-07-12 2006-01-19 Coreolis Inc. Apparatus and method for multiple organ assist
CA3123166A1 (en) * 2006-04-14 2007-10-25 Deka Products Limited Partnership Systems, devices and methods for fluid pumping, heat exchange, thermal sensing, and conductivity sensing
US10537671B2 (en) 2006-04-14 2020-01-21 Deka Products Limited Partnership Automated control mechanisms in a hemodialysis apparatus
US7887502B2 (en) 2006-09-15 2011-02-15 University Of Florida Research Foundation, Inc. Method for using photoplethysmography to optimize fluid removal during renal replacement therapy by hemodialysis or hemofiltration
US8409441B2 (en) 2007-02-27 2013-04-02 Deka Products Limited Partnership Blood treatment systems and methods
US9028691B2 (en) * 2007-02-27 2015-05-12 Deka Products Limited Partnership Blood circuit assembly for a hemodialysis system
US8425471B2 (en) * 2007-02-27 2013-04-23 Deka Products Limited Partnership Reagent supply for a hemodialysis system
CA2681912C (en) 2007-02-27 2015-09-29 Deka Products Limited Partnership Hemodialysis systems and methods
US8393690B2 (en) 2007-02-27 2013-03-12 Deka Products Limited Partnership Enclosure for a portable hemodialysis system
US9517295B2 (en) 2007-02-27 2016-12-13 Deka Products Limited Partnership Blood treatment systems and methods
US8491184B2 (en) * 2007-02-27 2013-07-23 Deka Products Limited Partnership Sensor apparatus systems, devices and methods
US8317492B2 (en) 2007-02-27 2012-11-27 Deka Products Limited Partnership Pumping cassette
US8357298B2 (en) * 2007-02-27 2013-01-22 Deka Products Limited Partnership Hemodialysis systems and methods
US8042563B2 (en) 2007-02-27 2011-10-25 Deka Products Limited Partnership Cassette system integrated apparatus
US8562834B2 (en) * 2007-02-27 2013-10-22 Deka Products Limited Partnership Modular assembly for a portable hemodialysis system
US20090107335A1 (en) 2007-02-27 2009-04-30 Deka Products Limited Partnership Air trap for a medical infusion device
US9199022B2 (en) 2008-09-12 2015-12-01 Fresenius Medical Care Holdings, Inc. Modular reservoir assembly for a hemodialysis and hemofiltration system
US8240636B2 (en) 2009-01-12 2012-08-14 Fresenius Medical Care Holdings, Inc. Valve system
US8105487B2 (en) 2007-09-25 2012-01-31 Fresenius Medical Care Holdings, Inc. Manifolds for use in conducting dialysis
US9358331B2 (en) 2007-09-13 2016-06-07 Fresenius Medical Care Holdings, Inc. Portable dialysis machine with improved reservoir heating system
US9308307B2 (en) 2007-09-13 2016-04-12 Fresenius Medical Care Holdings, Inc. Manifold diaphragms
US8597505B2 (en) 2007-09-13 2013-12-03 Fresenius Medical Care Holdings, Inc. Portable dialysis machine
US8535522B2 (en) 2009-02-12 2013-09-17 Fresenius Medical Care Holdings, Inc. System and method for detection of disconnection in an extracorporeal blood circuit
US20100056975A1 (en) * 2008-08-27 2010-03-04 Deka Products Limited Partnership Blood line connector for a medical infusion device
US8771508B2 (en) * 2008-08-27 2014-07-08 Deka Products Limited Partnership Dialyzer cartridge mounting arrangement for a hemodialysis system
US7879069B2 (en) * 2007-10-26 2011-02-01 Global Monitors, Inc. Anti-pooling vest for patients undergoing hemodialysis and in critical care
CA2960103C (en) 2007-11-29 2020-03-10 Fredenius Medical Care Holdings, Inc. System and method for conducting hemodialysis and hemofiltration
US10201647B2 (en) 2008-01-23 2019-02-12 Deka Products Limited Partnership Medical treatment system and methods using a plurality of fluid lines
US11833281B2 (en) 2008-01-23 2023-12-05 Deka Products Limited Partnership Pump cassette and methods for use in medical treatment system using a plurality of fluid lines
US20090281473A1 (en) * 2008-05-07 2009-11-12 Scheiber Lane Bernard Anti-Human Immunodeficiency Virus Surrogate Target Agent Technology Filter Intended to Neutralize or Remove Human Immunodeficiency Virus Virions From Blood
WO2010042667A2 (en) 2008-10-07 2010-04-15 Xcorporeal, Inc. Thermal flow meter
EP2334412B1 (en) 2008-10-07 2019-08-21 Fresenius Medical Care Holdings, Inc. Priming system and method for dialysis systems
EP2342003B1 (en) 2008-10-30 2018-09-26 Fresenius Medical Care Holdings, Inc. Modular, portable dialysis system
US9399091B2 (en) * 2009-09-30 2016-07-26 Medtronic, Inc. System and method to regulate ultrafiltration
CA2779296C (en) * 2009-10-30 2018-02-13 Deka Products Limited Partnership Apparatus and method for detecting disconnection of an intravascular access device
ES2853742T3 (en) * 2010-04-22 2021-09-17 Fresenius Medical Care Deutschland Gmbh Controller to control a filtration rate, appliances, devices and digital storage media
PL2380609T3 (en) * 2010-04-22 2017-12-29 Fresenius Medical Care Deutschland Gmbh Devices and controller for controlling of a filtration rate
US9750862B2 (en) 2011-04-29 2017-09-05 Medtronic, Inc. Adaptive system for blood fluid removal
DE102011076228A1 (en) * 2011-05-20 2012-11-22 Siemens Ag Arrangement and method for filtration
CA3166031A1 (en) 2011-05-24 2012-11-29 Deka Products Limited Partnership Hemodialysis system
US20130146541A1 (en) 2011-12-13 2013-06-13 Nxstage Medical, Inc. Fluid purification methods, devices, and systems
JP5914106B2 (en) * 2012-03-30 2016-05-11 日機装株式会社 Blood purification equipment
US9201036B2 (en) 2012-12-21 2015-12-01 Fresenius Medical Care Holdings, Inc. Method and system of monitoring electrolyte levels and composition using capacitance or induction
US9157786B2 (en) 2012-12-24 2015-10-13 Fresenius Medical Care Holdings, Inc. Load suspension and weighing system for a dialysis machine reservoir
US9433720B2 (en) 2013-03-14 2016-09-06 Fresenius Medical Care Holdings, Inc. Universal portable artificial kidney for hemodialysis and peritoneal dialysis
US20140263062A1 (en) 2013-03-14 2014-09-18 Fresenius Medical Care Holdings, Inc. Universal portable machine for online hemodiafiltration using regenerated dialysate
DE102013006562A1 (en) * 2013-04-16 2014-10-16 Fresenius Medical Care Deutschland Gmbh Method for determining the pressure in an extracorporeal circuit
EP3102107A4 (en) 2013-11-04 2018-02-07 Medtronic, Inc. Method and device to manage fluid volumes in the body
US9354640B2 (en) 2013-11-11 2016-05-31 Fresenius Medical Care Holdings, Inc. Smart actuator for valve
US10398448B2 (en) 2014-06-23 2019-09-03 Kpr U.S., Llc Arteriovenous fistula maturation
JP5851003B1 (en) 2014-09-12 2016-02-03 日機装株式会社 Blood purification equipment
DE102014113462A1 (en) * 2014-09-18 2016-03-24 Fresenius Medical Care Deutschland Gmbh Method and apparatus for accounting for patient feedback in blood treatment
US10220132B2 (en) 2014-12-19 2019-03-05 Fenwal, Inc. Biological fluid flow control apparatus and method
JP6517023B2 (en) 2015-01-23 2019-05-22 日機装株式会社 Blood purification device
JP6516559B2 (en) 2015-05-21 2019-05-22 日機装株式会社 Blood purification device
WO2016208705A1 (en) 2015-06-24 2016-12-29 日機装株式会社 Blood purifying device
JP6613062B2 (en) 2015-06-24 2019-11-27 日機装株式会社 Blood purification apparatus and blood purification system
JP6111351B1 (en) 2016-01-25 2017-04-05 日機装株式会社 Blood purification equipment
US10874790B2 (en) 2016-08-10 2020-12-29 Medtronic, Inc. Peritoneal dialysis intracycle osmotic agent adjustment
US10994064B2 (en) 2016-08-10 2021-05-04 Medtronic, Inc. Peritoneal dialysate flow path sensing
US11013843B2 (en) 2016-09-09 2021-05-25 Medtronic, Inc. Peritoneal dialysis fluid testing system
JP6998112B2 (en) 2016-09-12 2022-01-18 日機装株式会社 Blood purification device
JP6826852B2 (en) 2016-09-23 2021-02-10 日機装株式会社 Blood purification device
US10272187B2 (en) * 2017-02-22 2019-04-30 Fresenius Medical Care Holdings, Inc. System and methods for dialyzer flow rates estimation using measured dialyzer pressures
US20200237977A1 (en) * 2017-03-17 2020-07-30 Irras Ab Fluid Exchange System and Related Methods
EP3630221A4 (en) 2017-06-02 2021-03-10 Analiza, Inc. Absolute blood volume estimation device and method
US10625011B2 (en) * 2017-09-29 2020-04-21 Fresnius Medical Care Holdings, Inc. System and method for dialyzer evaluation
US10881347B2 (en) * 2017-12-29 2021-01-05 Fresenius Medical Care Holdings, Inc. Closed loop dialysis treatment using adaptive ultrafiltration rates
US20210236710A1 (en) * 2018-04-19 2021-08-05 Texas Children's Hospital Physiologic cardiovascular ph balanced counter current electrolyte transfer and fluid removal system
JP7144979B2 (en) * 2018-06-20 2022-09-30 日機装株式会社 Blood purification device and method for estimating patient's nutritional status by blood purification device
JP7055372B2 (en) * 2018-09-13 2022-04-18 学校法人 川崎学園 Blood pressure estimation method, actual blood pressure estimation method and blood purification device
US11806457B2 (en) 2018-11-16 2023-11-07 Mozarc Medical Us Llc Peritoneal dialysis adequacy meaurements
US11806456B2 (en) 2018-12-10 2023-11-07 Mozarc Medical Us Llc Precision peritoneal dialysis therapy based on dialysis adequacy measurements
WO2021138601A1 (en) * 2019-12-31 2021-07-08 Chf Solutions, Inc. Blood filtration system and plasma volume monitoring
US11850344B2 (en) 2021-08-11 2023-12-26 Mozarc Medical Us Llc Gas bubble sensor
US11965763B2 (en) 2021-11-12 2024-04-23 Mozarc Medical Us Llc Determining fluid flow across rotary pump
US11944733B2 (en) 2021-11-18 2024-04-02 Mozarc Medical Us Llc Sodium and bicarbonate control

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202764A (en) * 1978-10-02 1980-05-13 Baxter Travenol Laboratories, Inc. Ultrafiltration control system
US4936980A (en) * 1982-05-28 1990-06-26 Kuraray Co., Ltd. Apparatus and method for plasma separation
US5431811A (en) * 1992-05-19 1995-07-11 Hospal Ag Artificial kidney with device for filtering dialysis liquid
US5589077A (en) * 1993-09-20 1996-12-31 Sumitomo Chemical Company, Limited Liquid filtering and supply system controlling recirculation responsive to pressure difference across filter
US5660722A (en) * 1994-07-13 1997-08-26 Fresenius Ag Hemo(dia)filtration apparatus and filtrate flow regulator
US5792367A (en) * 1994-02-18 1998-08-11 Gambro Ab System and method for monitoring a flow of dialysis fluid in a dialysis machine
US5947689A (en) * 1997-05-07 1999-09-07 Scilog, Inc. Automated, quantitative, system for filtration of liquids having a pump controller

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2129165A5 (en) * 1971-03-17 1972-10-27 Rhone Poulenc Sa
US4080958A (en) 1976-02-27 1978-03-28 Datascope Corporation Apparatus for aiding and improving the blood flow in patients
DE2644062A1 (en) 1976-09-30 1978-04-06 Fraunhofer Ges Forschung Automatic regulator for haemodialysis appts. - with continuous extraction of water from patient during dialysis
DE2644584A1 (en) * 1976-10-02 1978-04-06 Klauschenz & Perrot DEVICE FOR DIALYZING THE BLOOD OF A PATIENT
US4086924A (en) 1976-10-06 1978-05-02 Haemonetics Corporation Plasmapheresis apparatus
GB1583023A (en) 1976-11-22 1981-01-21 Lavender A R Blood fractionating apparatus and process
US4469593A (en) * 1982-03-10 1984-09-04 Kabushiki Kaisha Toyota Chuo Kenkyusho Blood purification apparatus
US4680122A (en) * 1983-09-10 1987-07-14 Organon Teknika Corporation Ultrafiltration control for hemodialysis
EP0188451B1 (en) 1984-06-29 1991-12-11 BAXTER INTERNATIONAL INC. (a Delaware corporation) Blood extraction and reinfusion flow control system and method
FR2574664B1 (en) * 1984-12-14 1987-03-06 Issautier Gerald HEMODIALYSIS DEVICE FOR AUTOMATICALLY CONTROLLING WEIGHT LOSS
US4767399A (en) 1986-12-05 1988-08-30 Fisher Scientific Group Inc. Dba Imed Corporation Volumetric fluid withdrawal system
DE3709432A1 (en) 1987-03-21 1988-10-06 Fresenius Ag CAPILLARY FILTER ARRANGEMENT FOR THE STERILIZATION OF LIQUID MEDIA
US5114580A (en) 1989-06-20 1992-05-19 The Board Of Regents Of The University Of Washington Combined hemofiltration and hemodialysis system
US5350360A (en) 1990-03-01 1994-09-27 Michigan Transtech Corporation Implantable access devices
FR2680318B1 (en) 1991-08-14 1994-01-21 Hospal Industrie ARTIFICIAL KIDNEY AND ORDERING METHOD.
US5312550B1 (en) 1992-04-27 1996-04-23 Robert L Hester Method for detecting undesired dialysis recirculation
US5536237A (en) 1992-06-01 1996-07-16 Baxter International Inc. Blood extraction flow control calibration system and method
US5910252A (en) 1993-02-12 1999-06-08 Cobe Laboratories, Inc. Technique for extracorporeal treatment of blood
SE502222C2 (en) 1994-01-17 1995-09-18 Althin Medical Ab Method of dialysis
US5685989A (en) 1994-09-16 1997-11-11 Transonic Systems, Inc. Method and apparatus to measure blood flow and recirculation in hemodialysis shunts
US5591344A (en) 1995-02-13 1997-01-07 Aksys, Ltd. Hot water disinfection of dialysis machines, including the extracorporeal circuit thereof
SE508374C2 (en) 1995-09-12 1998-09-28 Gambro Med Tech Ab Method and apparatus for detecting the condition of a blood vessel access
EP0862378A4 (en) 1995-10-26 2000-01-18 Medisystems Technology Corp Pressure measurement in blood treatment
US5906589A (en) 1996-11-13 1999-05-25 Cobe Laboratories, Inc. Method and apparatus for occlusion monitoring using pressure waveform analysis
US6852090B2 (en) 1997-02-14 2005-02-08 Nxstage Medical, Inc. Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge
US20010016699A1 (en) 1997-02-14 2001-08-23 Jeffrey H. Burbank Hemofiltration system
US6979309B2 (en) 1997-02-14 2005-12-27 Nxstage Medical Inc. Systems and methods for performing blood processing and/or fluid exchange procedures
US7004924B1 (en) 1998-02-11 2006-02-28 Nxstage Medical, Inc. Methods, systems, and kits for the extracorporeal processing of blood
US6582385B2 (en) 1998-02-19 2003-06-24 Nstage Medical, Inc. Hemofiltration system including ultrafiltrate purification and re-infusion system
US6193681B1 (en) 1998-09-14 2001-02-27 American Immuno Tech, Llc. Septicemia prevention and treatment system
DE10047421C1 (en) 2000-09-26 2003-01-02 Klaus Sodemann Method and device for ultrafiltration control in blood treatment methods
US6689083B1 (en) * 2000-11-27 2004-02-10 Chf Solutions, Inc. Controller for ultrafiltration blood circuit which prevents hypotension by monitoring osmotic pressure in blood
US6572576B2 (en) 2001-07-07 2003-06-03 Nxstage Medical, Inc. Method and apparatus for leak detection in a fluid line
US7597677B2 (en) 2001-11-16 2009-10-06 National Quality Care, Inc. Wearable ultrafiltration device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202764A (en) * 1978-10-02 1980-05-13 Baxter Travenol Laboratories, Inc. Ultrafiltration control system
US4936980A (en) * 1982-05-28 1990-06-26 Kuraray Co., Ltd. Apparatus and method for plasma separation
US5431811A (en) * 1992-05-19 1995-07-11 Hospal Ag Artificial kidney with device for filtering dialysis liquid
US5589077A (en) * 1993-09-20 1996-12-31 Sumitomo Chemical Company, Limited Liquid filtering and supply system controlling recirculation responsive to pressure difference across filter
US5792367A (en) * 1994-02-18 1998-08-11 Gambro Ab System and method for monitoring a flow of dialysis fluid in a dialysis machine
US5660722A (en) * 1994-07-13 1997-08-26 Fresenius Ag Hemo(dia)filtration apparatus and filtrate flow regulator
US5947689A (en) * 1997-05-07 1999-09-07 Scilog, Inc. Automated, quantitative, system for filtration of liquids having a pump controller

Also Published As

Publication number Publication date
WO2002047609A9 (en) 2003-02-06
US6689083B1 (en) 2004-02-10
US7399289B2 (en) 2008-07-15
US20090024070A1 (en) 2009-01-22
US8070707B2 (en) 2011-12-06
US20040039324A1 (en) 2004-02-26
AU2002243218A1 (en) 2002-06-24
WO2002047609A2 (en) 2002-06-20

Similar Documents

Publication Publication Date Title
WO2002047609A3 (en) Feedback control of ultrafiltration to prevent hypotension using osmotic pressure
WO2002053098A3 (en) Feedback control of ultrafiltration to prevent hypotension
US5151082A (en) Apparatus and method for kidney dialysis using plasma in lieu of blood
CA2429369C (en) Apparatus and method for in-vivo plasmapheresis using periodic backflush
US5366630A (en) Artificial kidney and a method of controlling it
US3946731A (en) Apparatus for extracorporeal treatment of blood
WO2006011009A3 (en) A machine and a procedure for extracorporeal treatment of blood.
EP0096973B1 (en) Apparatus for plasma separation
CN105813665B (en) Device and method for adjusting and providing the pump rate of blood pump
AU5583098A (en) Device and method for preparation of substitution solution
EP1389475A3 (en) Process for controlling sodium concentration in a dialysate as prescribed
EP1604699A3 (en) Device and method for controlling infusion of a liquid in an extracorporeal blood circuit
JP2000107283A (en) Dialysis apparatus and washing priming method
WO2008024434A8 (en) Device for removing fluid from blood in a patient
EP1062960A3 (en) Method for determining the performance of a dialyser and dialysis apparatus therefor
KR100905984B1 (en) Apparatus for determining access flow
AU2002231285A1 (en) Apparatus and method for in-vivo plasmapheresis using periodic backflush
WO2001089599A3 (en) Method and apparatus for peripheral vein fluid removal in heart failure
EP0980685A3 (en) Peritoneal dialysis fluid and method for a continuous recirculating peritoneal dialysis using the same
JP2000107284A (en) Dialysis apparatus and washing priming method
CA2364677A1 (en) Device and a method for determining blood recirculation in a vascular access
JP4158334B2 (en) Blood purification equipment
JP4158333B2 (en) Blood purification equipment
Vanholder et al. Single needle haemodialysis
JPH059008Y2 (en)

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
COP Corrected version of pamphlet

Free format text: PAGES 1/8-8/8, DRAWINGS, REPLACED BY NEW PAGES 1/8-8/8; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP