WO2002038806A3 - Nachweis von nukleinsäure-polymorphismen - Google Patents

Nachweis von nukleinsäure-polymorphismen Download PDF

Info

Publication number
WO2002038806A3
WO2002038806A3 PCT/EP2001/013120 EP0113120W WO0238806A3 WO 2002038806 A3 WO2002038806 A3 WO 2002038806A3 EP 0113120 W EP0113120 W EP 0113120W WO 0238806 A3 WO0238806 A3 WO 0238806A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
nucleic acid
acid polymorphisms
polymorphisms
characterising
Prior art date
Application number
PCT/EP2001/013120
Other languages
English (en)
French (fr)
Other versions
WO2002038806A2 (de
Inventor
Rudolf Rigler
Lars Edman
Zeno Foeldes-Papp
Original Assignee
Gnothis Holding Sa
Rudolf Rigler
Lars Edman
Zeno Foeldes-Papp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10065631A external-priority patent/DE10065631A1/de
Application filed by Gnothis Holding Sa, Rudolf Rigler, Lars Edman, Zeno Foeldes-Papp filed Critical Gnothis Holding Sa
Priority to AU2002216035A priority Critical patent/AU2002216035A1/en
Priority to EP01993709A priority patent/EP1409721A2/de
Priority to US10/416,574 priority patent/US20040072200A1/en
Publication of WO2002038806A2 publication Critical patent/WO2002038806A2/de
Publication of WO2002038806A3 publication Critical patent/WO2002038806A3/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism

Abstract

Es werden Verfahren auf Einzelmolekülebene funktionierende Verfahren zur Charakterisierung von Nukleotidpolymorphismen beschrieben.
PCT/EP2001/013120 2000-11-13 2001-11-13 Nachweis von nukleinsäure-polymorphismen WO2002038806A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002216035A AU2002216035A1 (en) 2000-11-13 2001-11-13 Detection of nucleic acid polymorphisms
EP01993709A EP1409721A2 (de) 2000-11-13 2001-11-13 Nachweis von nukleinsäure-polymorphismen
US10/416,574 US20040072200A1 (en) 2000-11-13 2001-11-13 Detection of nucleic acid polymorphisms

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10056226.4 2000-11-13
DE10056226 2000-11-13
DE10065631A DE10065631A1 (de) 2000-11-13 2000-12-29 Nachweis von Nukleinsäure- Polymorphismen
DE10065631.5 2000-12-29

Publications (2)

Publication Number Publication Date
WO2002038806A2 WO2002038806A2 (de) 2002-05-16
WO2002038806A3 true WO2002038806A3 (de) 2004-02-19

Family

ID=26007647

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/013120 WO2002038806A2 (de) 2000-11-13 2001-11-13 Nachweis von nukleinsäure-polymorphismen

Country Status (4)

Country Link
US (1) US20040072200A1 (de)
EP (1) EP1409721A2 (de)
AU (1) AU2002216035A1 (de)
WO (1) WO2002038806A2 (de)

Families Citing this family (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4241038B2 (ja) 2000-10-30 2009-03-18 ザ ジェネラル ホスピタル コーポレーション 組織分析のための光学的な方法及びシステム
US9295391B1 (en) 2000-11-10 2016-03-29 The General Hospital Corporation Spectrally encoded miniature endoscopic imaging probe
US7865231B2 (en) 2001-05-01 2011-01-04 The General Hospital Corporation Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties
US7355716B2 (en) 2002-01-24 2008-04-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
ATE378424T1 (de) * 2002-08-12 2007-11-15 Gnothis Holding Sa Nachweis von einzelnukleotidpolymorphismen durch einzelmolekülanalyse
WO2004088361A2 (en) 2003-03-31 2004-10-14 The General Hospital Corporation Speckle reduction in optical coherence tomography by path length encoded angular compounding
US8054468B2 (en) * 2003-01-24 2011-11-08 The General Hospital Corporation Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands
WO2004071948A2 (en) * 2003-02-10 2004-08-26 Reveo, Inc. Micro-nozzle, nano-nozzle, manufacturing methods therefor, applications therefor
KR101386971B1 (ko) 2003-06-06 2014-04-18 더 제너럴 하스피탈 코포레이션 파장 동조 소스용 방법 및 장치
US7733497B2 (en) 2003-10-27 2010-06-08 The General Hospital Corporation Method and apparatus for performing optical imaging using frequency-domain interferometry
AU2004320269B2 (en) * 2004-05-29 2011-07-21 The General Hospital Corporation Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (OCT) imaging
WO2006014392A1 (en) * 2004-07-02 2006-02-09 The General Hospital Corporation Endoscopic imaging probe comprising dual clad fibre
US8081316B2 (en) * 2004-08-06 2011-12-20 The General Hospital Corporation Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography
US8208995B2 (en) 2004-08-24 2012-06-26 The General Hospital Corporation Method and apparatus for imaging of vessel segments
WO2006024014A2 (en) 2004-08-24 2006-03-02 The General Hospital Corporation Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample
US7365859B2 (en) 2004-09-10 2008-04-29 The General Hospital Corporation System and method for optical coherence imaging
EP2329759B1 (de) 2004-09-29 2014-03-12 The General Hospital Corporation System und Verfahren zur Abbildung optischer Kohärenz
US7995210B2 (en) 2004-11-24 2011-08-09 The General Hospital Corporation Devices and arrangements for performing coherence range imaging using a common path interferometer
JP2008521516A (ja) 2004-11-29 2008-06-26 ザ ジェネラル ホスピタル コーポレイション サンプル上の複数の地点を同時に照射し検出することによって光学画像生成を実行する構成、装置、内視鏡、カテーテル、及び方法
US20060228721A1 (en) * 2005-04-12 2006-10-12 Leamon John H Methods for determining sequence variants using ultra-deep sequencing
EP2325803A1 (de) 2005-04-28 2011-05-25 The General Hospital Corporation Beurteilung von optischen Kohärenztomographieinformationen für eine anatomische Struktur
US9060689B2 (en) 2005-06-01 2015-06-23 The General Hospital Corporation Apparatus, method and system for performing phase-resolved optical frequency domain imaging
ES2354287T3 (es) 2005-08-09 2011-03-11 The General Hospital Corporation Aparato y método para realizar una desmodulación en cuadratura por polarización en tomografía de coherencia óptica.
CN101365375B (zh) 2005-09-29 2013-09-11 通用医疗公司 用于经由谱编码进行光学成像的方法和设备
US7889348B2 (en) 2005-10-14 2011-02-15 The General Hospital Corporation Arrangements and methods for facilitating photoluminescence imaging
EP1971848B1 (de) 2006-01-10 2019-12-04 The General Hospital Corporation Systeme und verfahren zur datengenerierung auf der basis eines oder mehrerer spektral kodierter endoskopieverfahren
JP2009523574A (ja) * 2006-01-18 2009-06-25 ザ ジェネラル ホスピタル コーポレイション 1つ又は複数の内視鏡顕微鏡検査法を使用してデータを生成するシステム及び方法
PL1973466T3 (pl) 2006-01-19 2021-07-05 The General Hospital Corporation Balonowy cewnik do obrazowania
US8145018B2 (en) 2006-01-19 2012-03-27 The General Hospital Corporation Apparatus for obtaining information for a structure using spectrally-encoded endoscopy techniques and methods for producing one or more optical arrangements
GB0601183D0 (en) * 2006-01-20 2006-03-01 Perkinelmer Ltd Improvements in and relating to imaging
JP5524487B2 (ja) * 2006-02-01 2014-06-18 ザ ジェネラル ホスピタル コーポレイション コンフォーマルレーザ治療手順を用いてサンプルの少なくとも一部分に電磁放射を放射する方法及びシステム。
WO2007149603A2 (en) 2006-02-01 2007-12-27 The General Hospital Corporation Apparatus for applying a plurality of electro-magnetic radiations to a sample
JP5519152B2 (ja) 2006-02-08 2014-06-11 ザ ジェネラル ホスピタル コーポレイション 光学顕微鏡法を用いて解剖学的サンプルに関わる情報を取得するための装置
EP1987318B1 (de) 2006-02-24 2015-08-12 The General Hospital Corporation Verfahren und systeme zur durchführung von winkelaufgelöster optischer kohärenztomografie im fourier-bereich
EP2517616A3 (de) 2006-05-10 2013-03-06 The General Hospital Corporation Prozesse, Anordnungen und Systeme zur Bereitstellung der Frequenzbereichsabbildung einer Probe
WO2008049118A2 (en) 2006-10-19 2008-04-24 The General Hospital Corporation Apparatus and method for obtaining and providing imaging information associated with at least one portion of a sample and effecting such portion(s)
US8155730B2 (en) * 2006-10-24 2012-04-10 The Research Foundation Of State University Of New York Composition, method, system, and kit for optical electrophysiology
US20080206804A1 (en) * 2007-01-19 2008-08-28 The General Hospital Corporation Arrangements and methods for multidimensional multiplexed luminescence imaging and diagnosis
US7949019B2 (en) 2007-01-19 2011-05-24 The General Hospital Wavelength tuning source based on a rotatable reflector
CA2679511A1 (en) 2007-03-16 2008-09-25 454 Life Sciences Corporation System and method for detection of hiv drug resistant variants
EP2602651A3 (de) 2007-03-23 2014-08-27 The General Hospital Corporation Verfahren, Anordnungen und Vorrichtung zur Verwendung eines wellenlängengewobbelten Lasers anhand von Winkelabtastungs- und Dispersionsverfahren
US10534129B2 (en) 2007-03-30 2020-01-14 The General Hospital Corporation System and method providing intracoronary laser speckle imaging for the detection of vulnerable plaque
WO2008131082A1 (en) * 2007-04-17 2008-10-30 The General Hospital Corporation Apparatus and methods for measuring vibrations using spectrally-encoded endoscopy techniques
US8115919B2 (en) 2007-05-04 2012-02-14 The General Hospital Corporation Methods, arrangements and systems for obtaining information associated with a sample using optical microscopy
GB2450356A (en) * 2007-06-20 2008-12-24 Secretary Trade Ind Brit Method of Determining the Genotype of a Polymorphism using labelled nucleotides
JP5917803B2 (ja) 2007-07-31 2016-05-18 ザ ジェネラル ホスピタル コーポレイション 高速ドップラー光周波数領域撮像法のためのビーム走査パターンを放射するシステムおよび方法
EP2191254B1 (de) 2007-08-31 2017-07-19 The General Hospital Corporation System und verfahren für selbstinterferenz-fluoreszenzmikroskopie und damit assoziiertes rechnerzugriffsmedium
WO2009059034A1 (en) 2007-10-30 2009-05-07 The General Hospital Corporation System and method for cladding mode detection
US7898656B2 (en) 2008-04-30 2011-03-01 The General Hospital Corporation Apparatus and method for cross axis parallel spectroscopy
EP2274572A4 (de) 2008-05-07 2013-08-28 Gen Hospital Corp System, verfahren und computermedium zur verfolgung einer gefässbewegung in einer dreidimensionalen koronararterienmikroskopie
WO2009155536A2 (en) 2008-06-20 2009-12-23 The General Hospital Corporation Fused fiber optic coupler arrangement and method for use thereof
WO2010009136A2 (en) 2008-07-14 2010-01-21 The General Hospital Corporation Apparatus and methods for color endoscopy
JP5731394B2 (ja) 2008-12-10 2015-06-10 ザ ジェネラル ホスピタル コーポレイション 光サブサンプリングを通じて、光コヒーレンストモグラヒィーのイメージング深度範囲を伸ばすためのシステム、装置及び方法
US9615748B2 (en) * 2009-01-20 2017-04-11 The General Hospital Corporation Endoscopic biopsy apparatus, system and method
WO2010085775A2 (en) 2009-01-26 2010-07-29 The General Hospital Corporation System, method and computer-accessible medium for providing wide-field superresolution microscopy
US9351642B2 (en) 2009-03-12 2016-05-31 The General Hospital Corporation Non-contact optical system, computer-accessible medium and method for measurement at least one mechanical property of tissue using coherent speckle technique(s)
BR112012001042A2 (pt) * 2009-07-14 2016-11-22 Gen Hospital Corp equipamento e método de medição do fluxo de fluído dentro de estrutura anatômica.
ES2831223T3 (es) 2010-03-05 2021-06-07 Massachusetts Gen Hospital Aparato para proporcionar radiación electromagnética a una muestra
US9069130B2 (en) 2010-05-03 2015-06-30 The General Hospital Corporation Apparatus, method and system for generating optical radiation from biological gain media
US9795301B2 (en) 2010-05-25 2017-10-24 The General Hospital Corporation Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images
US9557154B2 (en) 2010-05-25 2017-01-31 The General Hospital Corporation Systems, devices, methods, apparatus and computer-accessible media for providing optical imaging of structures and compositions
EP2575591A4 (de) 2010-06-03 2017-09-13 The General Hospital Corporation Vorrichtung und verfahren für geräte zur abbildung von strukturen in oder an einem oder mehreren lumenorganen
US9510758B2 (en) 2010-10-27 2016-12-06 The General Hospital Corporation Apparatus, systems and methods for measuring blood pressure within at least one vessel
WO2013013049A1 (en) 2011-07-19 2013-01-24 The General Hospital Corporation Systems, methods, apparatus and computer-accessible-medium for providing polarization-mode dispersion compensation in optical coherence tomography
US10241028B2 (en) 2011-08-25 2019-03-26 The General Hospital Corporation Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
EP2769491A4 (de) 2011-10-18 2015-07-22 Gen Hospital Corp Vorrichtung und verfahren zur herstellung und/oder bereitstellung rezirkulierender optischer verzögerung(en)
WO2013148306A1 (en) 2012-03-30 2013-10-03 The General Hospital Corporation Imaging system, method and distal attachment for multidirectional field of view endoscopy
WO2013177154A1 (en) 2012-05-21 2013-11-28 The General Hospital Corporation Apparatus, device and method for capsule microscopy
JP6560126B2 (ja) 2013-01-28 2019-08-14 ザ ジェネラル ホスピタル コーポレイション 光周波数ドメインイメージングに重ね合わせされる拡散分光法を提供するための装置および方法
WO2014120791A1 (en) 2013-01-29 2014-08-07 The General Hospital Corporation Apparatus, systems and methods for providing information regarding the aortic valve
US11179028B2 (en) 2013-02-01 2021-11-23 The General Hospital Corporation Objective lens arrangement for confocal endomicroscopy
JP6378311B2 (ja) 2013-03-15 2018-08-22 ザ ジェネラル ホスピタル コーポレイション 物体を特徴付ける方法とシステム
WO2014186353A1 (en) 2013-05-13 2014-11-20 The General Hospital Corporation Detecting self-interefering fluorescence phase and amplitude
WO2015009932A1 (en) 2013-07-19 2015-01-22 The General Hospital Corporation Imaging apparatus and method which utilizes multidirectional field of view endoscopy
EP3021735A4 (de) 2013-07-19 2017-04-19 The General Hospital Corporation Bestimmung der augenbewegung mittels netzhautabbildung mit rückkopplung
EP3025173B1 (de) 2013-07-26 2021-07-07 The General Hospital Corporation Vorrichtung mit optische dispersion nutzender laseranordnung zur anwendung in der fourier-raum optischen kohärenztomographie
US9733460B2 (en) 2014-01-08 2017-08-15 The General Hospital Corporation Method and apparatus for microscopic imaging
WO2015116986A2 (en) 2014-01-31 2015-08-06 The General Hospital Corporation System and method for facilitating manual and/or automatic volumetric imaging with real-time tension or force feedback using a tethered imaging device
WO2015153982A1 (en) 2014-04-04 2015-10-08 The General Hospital Corporation Apparatus and method for controlling propagation and/or transmission of electromagnetic radiation in flexible waveguide(s)
WO2016015052A1 (en) 2014-07-25 2016-01-28 The General Hospital Corporation Apparatus, devices and methods for in vivo imaging and diagnosis

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314045A2 (de) * 1987-10-30 1989-05-03 Hitachi, Ltd. Gerät zur Elektrophorese mittels Wellenlängendispersion
WO1992015712A1 (en) * 1991-03-05 1992-09-17 Molecular Tool, Inc. Nucleic acid typing by polymerase extension of oligonucleotides using terminator mixtures
WO1998059066A1 (en) * 1997-06-25 1998-12-30 Orchid Biocomputer, Inc. Methods for the detection of multiple single nucleotide polymorphisms in a single reaction
WO2000018956A1 (de) * 1998-09-30 2000-04-06 Molecular Machines & Industries Gmbh Verfahren zur dns- oder rns-sequenzierung
WO2000031305A2 (en) * 1998-11-23 2000-06-02 Exact Laboratories, Inc. Primer extension methods utilizing donor and acceptor molecules for detecting nucleic acids
WO2000037680A1 (en) * 1998-12-18 2000-06-29 The Regents Of The University Of California Method for the detection of specific nucleic acid sequences by polymerase nucleotide incorporation
WO2000050172A1 (en) * 1999-02-23 2000-08-31 Caliper Technologies Corp. Manipulation of microparticles in microfluidic systems
WO2000058715A2 (en) * 1999-03-26 2000-10-05 The University Court Of The University Of Glasgow Assay system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185243A (en) * 1988-08-25 1993-02-09 Syntex (U.S.A.) Inc. Method for detection of specific nucleic acid sequences
US5119316A (en) * 1990-06-29 1992-06-02 E. I. Du Pont De Nemours And Company Method for determining dna sequences

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0314045A2 (de) * 1987-10-30 1989-05-03 Hitachi, Ltd. Gerät zur Elektrophorese mittels Wellenlängendispersion
WO1992015712A1 (en) * 1991-03-05 1992-09-17 Molecular Tool, Inc. Nucleic acid typing by polymerase extension of oligonucleotides using terminator mixtures
WO1998059066A1 (en) * 1997-06-25 1998-12-30 Orchid Biocomputer, Inc. Methods for the detection of multiple single nucleotide polymorphisms in a single reaction
WO2000018956A1 (de) * 1998-09-30 2000-04-06 Molecular Machines & Industries Gmbh Verfahren zur dns- oder rns-sequenzierung
WO2000031305A2 (en) * 1998-11-23 2000-06-02 Exact Laboratories, Inc. Primer extension methods utilizing donor and acceptor molecules for detecting nucleic acids
WO2000037680A1 (en) * 1998-12-18 2000-06-29 The Regents Of The University Of California Method for the detection of specific nucleic acid sequences by polymerase nucleotide incorporation
WO2000050172A1 (en) * 1999-02-23 2000-08-31 Caliper Technologies Corp. Manipulation of microparticles in microfluidic systems
WO2000058715A2 (en) * 1999-03-26 2000-10-05 The University Court Of The University Of Glasgow Assay system

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EIGEN M ET AL: "SORTING SINGLE MOLECULES: APPLICATION TO DIAGNOSTICS AND EVOLUTIONARY BIOTECHNOLOGY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 91, 1 June 1994 (1994-06-01), pages 5740 - 5747, XP002029412, ISSN: 0027-8424 *
GOESCH M ET AL: "HYDRODYNAMIC FLOW PROFILING IN MICROCHANNEL STRUCTURES BY SINGLE MOLECULE FLUORESCENCE CORRELATION SPECTROSCOPY", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 72, no. 14, 15 July 2000 (2000-07-15), pages 3260 - 3265, XP002180726, ISSN: 0003-2700 *
SCHWILLE P ET AL: "DUAL-COLOR FLUORESCENT CROSS-CORRELATION SPECTROSCOPY FOR MULTICOMPONENT DIFFUSIONAL ANALYSIS IN SOLUTION", BIOPHYSICAL JOURNAL, NEW YORK, US, US, vol. 72, no. 4, April 1997 (1997-04-01), pages 1878 - 1886, XP008008967, ISSN: 0006-3495 *

Also Published As

Publication number Publication date
EP1409721A2 (de) 2004-04-21
US20040072200A1 (en) 2004-04-15
AU2002216035A1 (en) 2002-05-21
WO2002038806A2 (de) 2002-05-16

Similar Documents

Publication Publication Date Title
WO2002038806A3 (de) Nachweis von nukleinsäure-polymorphismen
WO2003094838A3 (en) Simple catalytic dna biosensors for ions based on color changes
WO1999057325A3 (en) Enzymes mixture
AU2001245945A1 (en) Detection kits, such as nucleic acid arrays, for detecting the expression of 10,000 or more drosophila genes and uses thereof
WO2005044836A3 (de) Makromolekulare nukleotidverbindungen und methoden zu deren anwendung
WO2001019800A3 (en) Mediators of hedgehog signaling pathways, compositions and uses related thereto
AU2001276843A1 (en) Nucleic acid enzyme biosensor for ions
AU2001238030A1 (en) Detection of single nucleotide polymorphisms
WO2001094630A3 (en) Compositions and methods for array-based nucleic acid hybridization
WO2002026967A3 (en) Targeted gene correction by single-stranded oligodeoxynucleotides
WO2003040395A3 (en) Universal nucleotides for nucleic acid analysis
WO2003097794A3 (en) Universal-tagged oligonucleotide primers and methods of use
WO2004058990A3 (en) Genetic polymorphisms associated with stenosis, methods of detection and uses thereof
WO2002061133A3 (en) Nucleic acid detection using structured probes
WO2004081186A8 (en) Single nucleotide polymorphisms associated with stenosis, methods of detection and uses thereof
WO2003033732A3 (de) Echtzeitdetektion von dna-amplifikationsprodukten
WO2001047944A3 (en) Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
AU2001241733A1 (en) Methods for determining single nucleotide variations
AU2002232177A1 (en) Method of detecting nucleotide polymorphism
AU2001275192A1 (en) Determination of nucleotide sequence variations through limited primer extension
WO2001002571A3 (en) An interleukin-1 receptor antagonist and uses thereof
AU2002346498A1 (en) Thermus brockianus nucleic acid polymerases
WO2003048309A3 (en) Thermus thermophilus nucleic acid polymerases
AU2002346517A1 (en) Thermus oshimai nucleic acid polymerases
WO2001029262A3 (en) Genotyping reagents, kits and methods of use thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2001993709

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 10416574

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 2001993709

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP