WO2002038131A3 - Process - Google Patents

Process Download PDF

Info

Publication number
WO2002038131A3
WO2002038131A3 PCT/EP2001/012729 EP0112729W WO0238131A3 WO 2002038131 A3 WO2002038131 A3 WO 2002038131A3 EP 0112729 W EP0112729 W EP 0112729W WO 0238131 A3 WO0238131 A3 WO 0238131A3
Authority
WO
WIPO (PCT)
Prior art keywords
core
exterior
preparation
active agent
pharmaceutically active
Prior art date
Application number
PCT/EP2001/012729
Other languages
French (fr)
Other versions
WO2002038131A2 (en
Inventor
Luigi Martini
Philip Smith
Chi Leung Li
Original Assignee
Smithkline Beecham Plc
Smithkline Beecham Corp
Luigi Martini
Philip Smith
Chi Leung Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp, Luigi Martini, Philip Smith, Chi Leung Li filed Critical Smithkline Beecham Plc
Priority to EP01993458A priority Critical patent/EP1333813B1/en
Priority to DE60116530T priority patent/DE60116530T2/en
Priority to AU2002218280A priority patent/AU2002218280A1/en
Priority to JP2002540721A priority patent/JP4290981B2/en
Priority to US10/416,116 priority patent/US7923027B2/en
Publication of WO2002038131A2 publication Critical patent/WO2002038131A2/en
Publication of WO2002038131A3 publication Critical patent/WO2002038131A3/en
Priority to US13/029,198 priority patent/US8765065B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23B—TURNING; BORING
    • B23B37/00—Boring by making use of ultrasonic energy

Abstract

The present invention relates to a process using ultrasonic cutting for the preparation of an oral delivery device comprising a core which includes a pharmaceutically active agent covered by an outer coating which includes one or more openings communicating from the exterior of the device toward the core.
PCT/EP2001/012729 2000-11-08 2001-11-02 Process WO2002038131A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP01993458A EP1333813B1 (en) 2000-11-08 2001-11-02 Process for the preparation of an oral delivery device
DE60116530T DE60116530T2 (en) 2000-11-08 2001-11-02 PROCESS FOR THE MANUFACTURE OF AN ORAL MEDICINE
AU2002218280A AU2002218280A1 (en) 2000-11-08 2001-11-02 Process
JP2002540721A JP4290981B2 (en) 2000-11-08 2001-11-02 Oral delivery device manufacturing method
US10/416,116 US7923027B2 (en) 2000-11-08 2001-11-02 Process
US13/029,198 US8765065B2 (en) 2000-11-08 2011-02-17 Process

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0027471.2A GB0027471D0 (en) 2000-11-08 2000-11-08 Processes
GB0027471.2 2000-11-08

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10416116 A-371-Of-International 2001-11-02
US13/029,198 Division US8765065B2 (en) 2000-11-08 2011-02-17 Process

Publications (2)

Publication Number Publication Date
WO2002038131A2 WO2002038131A2 (en) 2002-05-16
WO2002038131A3 true WO2002038131A3 (en) 2002-09-12

Family

ID=9902924

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/012729 WO2002038131A2 (en) 2000-11-08 2001-11-02 Process

Country Status (9)

Country Link
US (2) US7923027B2 (en)
EP (2) EP1333813B1 (en)
JP (1) JP4290981B2 (en)
AT (2) ATE428407T1 (en)
AU (1) AU2002218280A1 (en)
DE (2) DE60116530T2 (en)
ES (2) ES2323879T3 (en)
GB (1) GB0027471D0 (en)
WO (1) WO2002038131A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9149438B2 (en) 2004-01-13 2015-10-06 Johnson & Johnson Consumer Inc. Rapidly disintegrating gelatinous coated tablets

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030153607A1 (en) * 1998-11-12 2003-08-14 Smithkline Beecham P.L.C. Novel composition and use
US20040081697A1 (en) * 1998-11-12 2004-04-29 Smithkline Beecham P.L.C. Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent
ATE404179T1 (en) * 2001-09-28 2008-08-15 Mcneil Ppc Inc DOSAGE FORMS WITH CORE AND OUTER SHELL
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
PE20030800A1 (en) * 2002-02-12 2003-10-31 Glaxo Group Ltd CONTROLLED RELEASE ORAL DOSAGE FORM
US8637512B2 (en) * 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
RU2005108576A (en) * 2002-09-28 2005-09-20 МакНЕЙЛ-ППС, ИНК. (US) POLYMERIC COMPOSITION AND CONTAINING ITS MEDICINAL FORMS
GB0318824D0 (en) * 2003-08-11 2003-09-10 Glaxo Group Ltd Novel composition
WO2005051325A2 (en) * 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Carvedilol compositions methods of treatment and delivery
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7404708B2 (en) * 2004-12-07 2008-07-29 Mcneil-Ppc, Inc. System and process for providing at least one opening in dosage forms
JP2009522259A (en) * 2005-12-30 2009-06-11 エーシーシーユー−ブレイク テクノロジーズ，インク． Adhesive bonded dosage form
US8273105B2 (en) 2008-02-20 2012-09-25 Tyco Healthcare Group Lp Compound barb medical device and method
BRPI0822655A2 (en) 2008-06-04 2015-06-30 Colgate Palmolive Co Oral Care Implement and System
CA2731008A1 (en) * 2008-07-18 2010-01-21 Valeant Pharmaceuticals International Modified release formulation and methods of use
US20100323015A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
US20100323016A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
US20220218719A1 (en) 2019-05-17 2022-07-14 Glaxosmithkline Intellectual Property Development Limited Matrix composition comprising (s)-5-benzyl-n-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-4h-1,2,4-triazole-3-carboxamide

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004614A (en) * 1988-08-26 1991-04-02 Forum Chemicals Ltd. Controlled release device with an impermeable coating having an orifice for release of drug
WO2001032149A1 (en) * 1999-10-29 2001-05-10 Merck & Co., Inc. Osmotic controlled release drug delivery device

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Publication number Priority date Publication date Assignee Title
DE1575050A1 (en) * 1966-01-12 1972-04-13 Misto Gen Equipment Co Ultrasonic fog generator
US4447235A (en) * 1981-05-07 1984-05-08 John M. Clarke Thoracentesis device
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
EP0303769A3 (en) * 1987-08-18 1989-10-25 Balzers Aktiengesellschaft Device for the transmission of rotary movements through a wall of a vacuum chamber
JPH02124251A (en) 1988-10-28 1990-05-11 Tanaka Kikinzoku Kogyo Kk Working method for small hole
US5123903A (en) * 1989-08-10 1992-06-23 Medical Products Development, Inc. Disposable aspiration sleeve for ultrasonic lipectomy
US5317932A (en) * 1992-02-28 1994-06-07 The Dow Chemical Company Sample probe
US5300046A (en) * 1992-03-30 1994-04-05 Symbiosis Corporation Thoracentesis sheath catheter assembly
US5674235A (en) * 1995-05-10 1997-10-07 Ultralase Technologies International Ultrasonic surgical cutting instrument
JPH1024491A (en) 1996-07-11 1998-01-27 Seidensha Denshi Kogyo Kk Ultrasonic machining apparatus
US6783662B2 (en) * 1999-03-18 2004-08-31 Exxonmobil Research And Engineering Company Cavitation enhanced liquid atomization
EP1202747A1 (en) * 1999-07-20 2002-05-08 Merck & Co., Inc. Sustained release drug dispersion delivery device
US7708504B2 (en) * 2005-08-29 2010-05-04 Savannah River Nuclear Solutions, Llc Pneumatic conveyance apparatus and process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004614A (en) * 1988-08-26 1991-04-02 Forum Chemicals Ltd. Controlled release device with an impermeable coating having an orifice for release of drug
WO2001032149A1 (en) * 1999-10-29 2001-05-10 Merck & Co., Inc. Osmotic controlled release drug delivery device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9149438B2 (en) 2004-01-13 2015-10-06 Johnson & Johnson Consumer Inc. Rapidly disintegrating gelatinous coated tablets

Also Published As

Publication number Publication date
EP1333813B1 (en) 2006-01-04
DE60138428D1 (en) 2009-05-28
JP4290981B2 (en) 2009-07-08
EP1333813A2 (en) 2003-08-13
AU2002218280A1 (en) 2002-05-21
DE60116530T2 (en) 2006-08-10
US20110131754A1 (en) 2011-06-09
DE60116530D1 (en) 2006-03-30
ATE314839T1 (en) 2006-02-15
EP1655024B1 (en) 2009-04-15
ES2323879T3 (en) 2009-07-27
US20040062806A1 (en) 2004-04-01
WO2002038131A2 (en) 2002-05-16
US7923027B2 (en) 2011-04-12
GB0027471D0 (en) 2000-12-27
JP2004512903A (en) 2004-04-30
ATE428407T1 (en) 2009-05-15
US8765065B2 (en) 2014-07-01
EP1655024A1 (en) 2006-05-10
ES2256329T3 (en) 2006-07-16

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