WO2002037944A3 - Multiplexed cell analysis system - Google Patents

Multiplexed cell analysis system Download PDF

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Publication number
WO2002037944A3
WO2002037944A3 PCT/US2001/051413 US0151413W WO0237944A3 WO 2002037944 A3 WO2002037944 A3 WO 2002037944A3 US 0151413 W US0151413 W US 0151413W WO 0237944 A3 WO0237944 A3 WO 0237944A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis system
cell analysis
multiplexed cell
multiplexed
amalysis
Prior art date
Application number
PCT/US2001/051413
Other languages
French (fr)
Other versions
WO2002037944A2 (en
Inventor
Ilva Ravkin
Simon Goldbard
Michael A Zarowitz
Oren E Beske
Original Assignee
Virtual Arrays Inc
Ilva Ravkin
Simon Goldbard
Michael A Zarowitz
Oren E Beske
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virtual Arrays Inc, Ilva Ravkin, Simon Goldbard, Michael A Zarowitz, Oren E Beske filed Critical Virtual Arrays Inc
Priority to GB0311360A priority Critical patent/GB2384777B/en
Priority to JP2002540546A priority patent/JP2004537712A/en
Priority to AU2002236691A priority patent/AU2002236691A1/en
Priority to CA002424176A priority patent/CA2424176A1/en
Priority to EP01986240A priority patent/EP1395601A4/en
Priority to AU3669102A priority patent/AU3669102A/en
Priority to US10/120,900 priority patent/US7557070B2/en
Publication of WO2002037944A2 publication Critical patent/WO2002037944A2/en
Priority to EP02807992A priority patent/EP1585958A4/en
Priority to AU2002368207A priority patent/AU2002368207A1/en
Priority to US10/273,605 priority patent/US20030129654A1/en
Priority to PCT/US2002/033350 priority patent/WO2004034012A2/en
Priority to US10/282,904 priority patent/US20030134330A1/en
Priority to US10/382,797 priority patent/US20030166015A1/en
Priority to US10/382,818 priority patent/US20030219800A1/en
Priority to US10/407,630 priority patent/US20030207249A1/en
Priority to US10/444,573 priority patent/US20040018485A1/en
Publication of WO2002037944A3 publication Critical patent/WO2002037944A3/en
Priority to US10/842,954 priority patent/US7338773B2/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00513—Essentially linear supports
    • B01J2219/0052—Essentially linear supports in the shape of elongated tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00533—Sheets essentially rectangular
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00545—Colours
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00565—Electromagnetic means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00621—Delimitation of the attachment areas by physical means, e.g. trenches, raised areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00623—Immobilisation or binding
    • B01J2219/00626—Covalent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00702—Processes involving means for analysing and characterising the products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/0074—Biological products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/0074—Biological products
    • B01J2219/00743—Cells
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Abstract

Systems including apparatus, methods, compositions, and kits for multiplexed amalysis of biological systems using nonpositional and/or positional arrays of coded carriers.
PCT/US2001/051413 1999-04-15 2001-10-18 Multiplexed cell analysis system WO2002037944A2 (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GB0311360A GB2384777B (en) 2000-10-18 2001-10-18 Multiplexed cell analysis system
JP2002540546A JP2004537712A (en) 2000-10-18 2001-10-18 Multiple cell analysis system
AU2002236691A AU2002236691A1 (en) 2000-10-18 2001-10-18 Multiplexed cell analysis system
CA002424176A CA2424176A1 (en) 2000-10-18 2001-10-18 Multiplexed cell analysis system
EP01986240A EP1395601A4 (en) 2000-10-18 2001-10-18 Multiplexed cell analysis system
AU3669102A AU3669102A (en) 2000-10-18 2001-10-19 Multiplexed cell analysis system
US10/120,900 US7557070B2 (en) 2000-10-18 2002-04-10 Multiplexed cell analysis system
PCT/US2002/033350 WO2004034012A2 (en) 2001-10-18 2002-10-18 Coded particles for multiplexed analysis of biological samples
AU2002368207A AU2002368207A1 (en) 2001-10-18 2002-10-18 Coded particles for multiplexed analysis of biological samples
EP02807992A EP1585958A4 (en) 2001-10-18 2002-10-18 Coded particles for multiplexed analysis of biological samples
US10/273,605 US20030129654A1 (en) 1999-04-15 2002-10-18 Coded particles for multiplexed analysis of biological samples
US10/282,904 US20030134330A1 (en) 1999-04-15 2002-10-28 Chemical-library composition and method
US10/382,797 US20030166015A1 (en) 1999-04-15 2003-03-05 Multiplexed analysis of cell-substrate interactions
US10/382,818 US20030219800A1 (en) 2001-10-18 2003-03-05 Multiplexed cell transfection using coded carriers
US10/407,630 US20030207249A1 (en) 1999-04-15 2003-04-04 Connection of cells to substrates using association pairs
US10/444,573 US20040018485A1 (en) 1999-04-15 2003-05-23 Multiplexed analysis of cells
US10/842,954 US7338773B2 (en) 2000-04-14 2004-05-10 Multiplexed assays of cell migration

Applications Claiming Priority (21)

Application Number Priority Date Filing Date Title
US24171400P 2000-10-18 2000-10-18
US60/241,714 2000-10-18
US25941600P 2000-12-28 2000-12-28
US60/259,416 2000-12-28
US29386301P 2001-05-24 2001-05-24
US60/293,863 2001-05-24
US29926701P 2001-06-18 2001-06-18
US60/299,267 2001-06-18
US29981001P 2001-06-20 2001-06-20
US60/299,810 2001-06-20
US30765001P 2001-07-24 2001-07-24
US30764901P 2001-07-24 2001-07-24
US60/307,649 2001-07-24
US60/307,650 2001-07-24
US31054001P 2001-08-06 2001-08-06
US60/310,540 2001-08-06
US31740901P 2001-09-04 2001-09-04
US60/317,409 2001-09-04
US31815601P 2001-09-07 2001-09-07
US60/318,156 2001-09-07
US32861501P 2001-10-10 2001-10-10

Publications (2)

Publication Number Publication Date
WO2002037944A2 WO2002037944A2 (en) 2002-05-16
WO2002037944A3 true WO2002037944A3 (en) 2003-12-24

Family

ID=27582746

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/051413 WO2002037944A2 (en) 1999-04-15 2001-10-18 Multiplexed cell analysis system

Country Status (4)

Country Link
AU (1) AU2002236691A1 (en)
CA (1) CA2424176A1 (en)
GB (1) GB2384777B (en)
WO (1) WO2002037944A2 (en)

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US20040115692A1 (en) * 2000-04-03 2004-06-17 Cytyc Corporation Methods, compositions and apparatuses for detecting a target in a preservative solution
US7338773B2 (en) 2000-04-14 2008-03-04 Millipore Corporation Multiplexed assays of cell migration
US6977152B2 (en) 2001-09-07 2005-12-20 Virtual Arrays, Inc. Biological assays using coded RNA reporters
AU2002368207A1 (en) * 2001-10-18 2004-05-04 Virtual Arrays, Inc. Coded particles for multiplexed analysis of biological samples
US7381375B2 (en) 2001-10-26 2008-06-03 Millipore Corporation Assay systems with adjustable fluid communication
AU2003213790A1 (en) * 2002-03-05 2003-09-22 Vitra Bioscience, Inc. Multiplexed analysis of cell-substrate interactions
AU2003241871A1 (en) * 2002-05-28 2003-12-12 National Institute Of Advanced Industrial Science And Technology Chemical sensor system
GB2391230A (en) * 2002-07-26 2004-02-04 Smartbead Technologies Ltd Multiparameter assays using coded supports
US7105347B2 (en) 2002-07-30 2006-09-12 Corning Incorporated Method and device for protein delivery into cells
US7691580B2 (en) 2003-01-29 2010-04-06 Corning Incorporated Reverse protein delivery into cells on coded microparticles
US7390628B2 (en) * 2003-12-23 2008-06-24 University Of Florida Research Foundation, Inc. Microparticle-based diagnostic methods
GB2423581A (en) * 2005-02-28 2006-08-30 Smartbead Technologies Ltd Particulate sets carrying a unique identifier for assays
DE102008057067A1 (en) * 2008-11-13 2010-05-20 BF-BIOlabs Schneider und Zeltz GbR (Vertretungsberechtigten Gesellschafter: Dr. Patric Zeltz 79211 Denzlingen und Stephan Schneider 79211 Denzlingen Apparatus for parallel micro-array experiments, e.g. in DNA analysis, has a micro-titration plate with reaction vessels and a micro-array to one side of them
CN102918376B (en) 2010-05-28 2015-07-15 奥林巴斯株式会社 Cell sorter, cell sorting system, and cell sorting method
CN103221800B (en) 2010-11-19 2015-07-15 奥林巴斯株式会社 Method for preparing biological sample
JP5907959B2 (en) 2011-05-20 2016-04-26 オリンパス株式会社 Manufacturing method of substrate sheet
JP5996550B2 (en) 2011-11-24 2016-09-21 オリンパス株式会社 Cell sorting device and cell sorting method
CN103645308B (en) * 2013-12-09 2015-06-03 东南大学 Two-dimensional coding method of micro-carrier
JP7018023B2 (en) 2016-04-14 2022-02-09 モーガン イノベーション アンド テクノロジー リミテッド Methods and Devices for Measuring Levels of Subject in Body Fluids

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EP0871777A4 (en) * 1995-11-30 2001-12-19 Wlodeck Mandecki Electronically-solid-phase assay biomolecules
US6210910B1 (en) * 1998-03-02 2001-04-03 Trustees Of Tufts College Optical fiber biosensor array comprising cell populations confined to microcavities
US6093370A (en) * 1998-06-11 2000-07-25 Hitachi, Ltd. Polynucleotide separation method and apparatus therefor
US7225082B1 (en) * 1999-10-01 2007-05-29 Oxonica, Inc. Colloidal rod particles as nanobar codes

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
US6083763A (en) * 1996-12-31 2000-07-04 Genometrix Inc. Multiplexed molecular analysis apparatus and method

Non-Patent Citations (1)

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Title
See also references of EP1395601A4 *

Also Published As

Publication number Publication date
GB0311360D0 (en) 2003-06-25
CA2424176A1 (en) 2002-05-16
GB2384777B (en) 2005-03-02
AU2002236691A1 (en) 2002-05-21
GB2384777A (en) 2003-08-06
WO2002037944A2 (en) 2002-05-16

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