WO2002034113A3 - Methods and instruments for treating pseudoarthrosis - Google Patents

Methods and instruments for treating pseudoarthrosis Download PDF

Info

Publication number
WO2002034113A3
WO2002034113A3 PCT/US2001/045479 US0145479W WO0234113A3 WO 2002034113 A3 WO2002034113 A3 WO 2002034113A3 US 0145479 W US0145479 W US 0145479W WO 0234113 A3 WO0234113 A3 WO 0234113A3
Authority
WO
WIPO (PCT)
Prior art keywords
pseudoarthrosis
instruments
drill
methods
treating
Prior art date
Application number
PCT/US2001/045479
Other languages
French (fr)
Other versions
WO2002034113A2 (en
Inventor
William F Mckay
Original Assignee
Sdgi Holdings Inc
William F Mckay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sdgi Holdings Inc, William F Mckay filed Critical Sdgi Holdings Inc
Priority to AU2006902A priority Critical patent/AU2006902A/en
Priority to JP2002537173A priority patent/JP2004512078A/en
Priority to AU2002220069A priority patent/AU2002220069B2/en
Priority to US10/399,836 priority patent/US8002775B2/en
Priority to EP01988541A priority patent/EP1335771A4/en
Priority to CA002426402A priority patent/CA2426402A1/en
Publication of WO2002034113A2 publication Critical patent/WO2002034113A2/en
Publication of WO2002034113A3 publication Critical patent/WO2002034113A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/446—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or elliptical cross-section substantially parallel to the axis of the spine, e.g. cylinders or frustocones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/30199—Three-dimensional shapes
    • A61F2002/30224—Three-dimensional shapes cylindrical
    • A61F2002/30235—Three-dimensional shapes cylindrical tubular, e.g. sleeves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30593—Special structural features of bone or joint prostheses not otherwise provided for hollow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0069—Three-dimensional shapes cylindrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells

Abstract

Methods, instruments, and kits for treating spinal pseudoarthrosis are provided. In one embodiment, a method includes delivering to a location of spinal pseudoarthrosis an effective amount of an osteoinductive composition that includes an injectible osteoinductive composition that includes an injectible osteoinductive composition in a pharmaceutically acceptable carrier. In other embodiments, cannulated drills 10, 10', 10'' and surgical instrument assemblies, 50, 50' including a drill and a syringe 60 and 60' wherein the syringe has a distal end that is matingly engaged to a proximal end of the drill are provided. The drill and other instruments, instrument assemblies, and kits formed therefrom may advantageously be used in a method for treating pseudoarthrosis.
PCT/US2001/045479 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis WO2002034113A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2006902A AU2006902A (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis
JP2002537173A JP2004512078A (en) 2000-10-24 2001-10-24 Methods and devices for treating pseudoarthritis
AU2002220069A AU2002220069B2 (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis
US10/399,836 US8002775B2 (en) 2001-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis
EP01988541A EP1335771A4 (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis
CA002426402A CA2426402A1 (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24295000P 2000-10-24 2000-10-24
US60/242,950 2000-10-24

Publications (2)

Publication Number Publication Date
WO2002034113A2 WO2002034113A2 (en) 2002-05-02
WO2002034113A3 true WO2002034113A3 (en) 2002-10-24

Family

ID=22916758

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/045479 WO2002034113A2 (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis

Country Status (5)

Country Link
EP (1) EP1335771A4 (en)
JP (1) JP2004512078A (en)
AU (2) AU2006902A (en)
CA (1) CA2426402A1 (en)
WO (1) WO2002034113A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US8002775B2 (en) 2001-10-24 2011-08-23 Warsaw Orthopedic, Inc. Methods and instruments for treating pseudoarthrosis
WO2003094617A2 (en) * 2002-05-06 2003-11-20 Genentech, Inc. Use of vegf for treating bone defects
FR2860422A1 (en) * 2003-10-02 2005-04-08 Emmanuel Berque Biocompatible adhesive substance applying device for prosthetic implant, has inner valve for closing catheters distal end and for opening distal end when manual thrust is applied on piston of syringe with respect of body
CA2602479A1 (en) * 2005-03-22 2006-09-28 Warsaw Orthopedic, Inc. Mechanisms of osteoinduction by lim mineralization protein-1 (lmp-1)
US8083722B2 (en) 2005-04-29 2011-12-27 Warsaw Orthopedic, Inc Instrumentation for injection of therapeutic fluid into joints
US7850656B2 (en) 2005-04-29 2010-12-14 Warsaw Orthopedic, Inc. Devices and methods for delivering medical agents
WO2010040076A2 (en) * 2008-10-02 2010-04-08 Trans1, Inc. Method and apparatus for bone graft insertion
WO2011111301A1 (en) * 2010-03-09 2011-09-15 国立大学法人神戸大学 Inter-spinous process implant

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824087A (en) * 1994-04-11 1998-10-20 Aberdeen University And Plasma Biotal Limited Bone regeneration
US6300127B1 (en) * 1997-07-30 2001-10-09 Emory University Bone mineralization proteins, DNA, vectors, expression systems

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013080A (en) * 1974-10-03 1977-03-22 Froning Edward C Cannula connector and direction indicator means for injection system
JPS58155867A (en) * 1982-03-12 1983-09-16 テルモ株式会社 Drill needle and medical container with drill needle
US6241734B1 (en) * 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
JP3424049B2 (en) * 1994-03-09 2003-07-07 山之内製薬株式会社 Bone formation implant
JP3125579B2 (en) * 1994-05-24 2001-01-22 三菱マテリアル株式会社 Biological cement filling equipment
US5584839A (en) * 1994-12-12 1996-12-17 Gieringer; Robert E. Intraarticular drill guide and arthroscopic methods
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US5779708A (en) * 1996-08-15 1998-07-14 Cyberdent, Inc. Intraosseous drug delivery device and method
EP0936929B1 (en) * 1996-10-16 2004-06-23 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
IL128261A0 (en) * 1999-01-27 1999-11-30 Disc O Tech Medical Tech Ltd Expandable element
JPH11313674A (en) * 1998-04-30 1999-11-16 Hoechst Marion Roussel Kk Human bmp-4 promotor and screening of bone-related substance using the same
WO2000049978A1 (en) * 1999-02-22 2000-08-31 Guagliano Peter A Method of treating an intervertebral disk

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824087A (en) * 1994-04-11 1998-10-20 Aberdeen University And Plasma Biotal Limited Bone regeneration
US6300127B1 (en) * 1997-07-30 2001-10-09 Emory University Bone mineralization proteins, DNA, vectors, expression systems

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1335771A4 *

Also Published As

Publication number Publication date
EP1335771A4 (en) 2006-06-07
AU2002220069B2 (en) 2005-12-15
EP1335771A2 (en) 2003-08-20
AU2006902A (en) 2002-05-06
JP2004512078A (en) 2004-04-22
WO2002034113A2 (en) 2002-05-02
CA2426402A1 (en) 2002-05-02

Similar Documents

Publication Publication Date Title
Ellis Iii et al. Lag screw fixation of anterior mandibular fractures
WO2004008949A3 (en) Method and apparatus for spinal fixation
AU2003260121A1 (en) Introduction system for minimally invasive surgical instruments
AU2002352035A1 (en) Surgical auxiliary instrument
WO2003103507A3 (en) Hernia mesh tacks
WO2005020827A3 (en) Devices and techniques for a minimally invasive disc space preparation and implant insertion
WO2002000119A3 (en) Surgical procedures and instruments
FR2844988B1 (en) SURGICAL TOOL FOR TREATING INCONTINENCE
WO2003037160A3 (en) Locking device for intramedullary pin fixation
WO2001037744A3 (en) Surgical screw delivery system and method
EP1302180A3 (en) Interference screws having increased proximal diameter
AU2001284857A1 (en) Surgical instrumentation and method for treatment of the spine
HK1075193A1 (en) Hand-held instruments that access interior body regions
WO2003043488A3 (en) Proximal anchors for bone fixation system
WO2004098453A3 (en) Proximal anchors for bone fixation system
WO2003024300A3 (en) Surgical suturing instrument and method of use
ATE255368T1 (en) INTRODUCTION GUIDE TO BONE FIXATION DEVICES
WO1998048687A3 (en) Surgical instrument with rotatably mounted offset end effector and method of using the same
EP1095624A3 (en) Femoral milling instrumentation for use in total knee arthroplasty
WO2005032358A3 (en) Methods, systems and apparatuses for performing minimally invasive spinal procedures
BG104982A (en) Device and method for resecting body tissues
WO2001060424A3 (en) Implantable tissues infused with growth factors and other additives
WO1996001074A3 (en) Method and apparatus for making additional incisions in laparoscopic surgery
AU2118601A (en) Ankle replacement system
ATE432051T1 (en) DISTAL BONE ANCHORS FOR BONE FIXATION WITH SECONDARY COMPRESSION

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2426402

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2002537173

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2002220069

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2001988541

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001988541

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 10399836

Country of ref document: US

WWG Wipo information: grant in national office

Ref document number: 2002220069

Country of ref document: AU