WO2002020645A3 - Polymer matrices prepared by supercritical fluid processing techniques - Google Patents

Polymer matrices prepared by supercritical fluid processing techniques Download PDF

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Publication number
WO2002020645A3
WO2002020645A3 PCT/US2001/026457 US0126457W WO0220645A3 WO 2002020645 A3 WO2002020645 A3 WO 2002020645A3 US 0126457 W US0126457 W US 0126457W WO 0220645 A3 WO0220645 A3 WO 0220645A3
Authority
WO
WIPO (PCT)
Prior art keywords
reactor
supercritical fluid
polymer matrices
processing techniques
fluid processing
Prior art date
Application number
PCT/US2001/026457
Other languages
French (fr)
Other versions
WO2002020645A2 (en
Inventor
Frederick S Mandel
J Don Wang
Original Assignee
Ferro Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferro Corp filed Critical Ferro Corp
Priority to AU2001285255A priority Critical patent/AU2001285255A1/en
Publication of WO2002020645A2 publication Critical patent/WO2002020645A2/en
Publication of WO2002020645A3 publication Critical patent/WO2002020645A3/en
Priority to US12/027,728 priority patent/US8568766B2/en
Priority to US13/804,161 priority patent/US20130295042A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/005—Processes for mixing polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/405—Methods of mixing liquids with liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/49—Mixing systems, i.e. flow charts or diagrams
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
    • B01F27/90—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with paddles or arms 
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/002—Methods
    • B29B7/005—Methods for mixing in batches
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29B—PREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
    • B29B7/00—Mixing; Kneading
    • B29B7/80—Component parts, details or accessories; Auxiliary operations
    • B29B7/86—Component parts, details or accessories; Auxiliary operations for working at sub- or superatmospheric pressure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/2805—Mixing plastics, polymer material ingredients, monomers or oligomers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/04—Specific aggregation state of one or more of the phases to be mixed
    • B01F23/043—Mixing fluids or with fluids in a supercritical state, in supercritical conditions or variable density fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/70—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming
    • B01F33/71—Mixers specially adapted for working at sub- or super-atmospheric pressure, e.g. combined with de-foaming working at super-atmospheric pressure, e.g. in pressurised vessels
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Abstract

Polymer matrices for use in orthopedic, pharmaceutical, and similar mixtures are prepared by mixing two or more polymers and a process medium in a reactor to form a supercritical fluid slurry. The process medium preferably is carbon dioxide which is supplied to the reactor in a supercritical state or which is heated and pressurized in the reactor to attain a supercritical state. After mixing for a period of time, the slurry either is left in the reactor or is discharged into a receiving vessel. The process medium is separated from the polymers and removed, leaving behind finely divided particles.
PCT/US2001/026457 2000-08-24 2001-08-24 Polymer matrices prepared by supercritical fluid processing techniques WO2002020645A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001285255A AU2001285255A1 (en) 2000-09-08 2001-08-24 Polymer matrices prepared by supercritical fluid processing techniques
US12/027,728 US8568766B2 (en) 2000-08-24 2008-02-07 Peptides and peptide mimetics to treat pathologies associated with eye disease
US13/804,161 US20130295042A1 (en) 2000-08-24 2013-03-14 Peptides and Peptide Mimetics to Treat Pathologies Associated With Eye Disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/658,251 2000-09-08
US09/658,251 US6521258B1 (en) 2000-09-08 2000-09-08 Polymer matrices prepared by supercritical fluid processing techniques

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US09/896,841 Continuation-In-Part US6933279B2 (en) 2000-08-24 2001-06-29 Orally administered peptides to ameliorate atherosclerosis
US10/187,215 Continuation-In-Part US7144862B2 (en) 2000-08-24 2002-06-28 Orally administered peptides to ameliorate atherosclerosis

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/187,215 Continuation-In-Part US7144862B2 (en) 2000-08-24 2002-06-28 Orally administered peptides to ameliorate atherosclerosis
US10/273,386 Continuation-In-Part US7166578B2 (en) 2000-08-24 2002-10-16 Orally administered peptides synergize statin activity

Publications (2)

Publication Number Publication Date
WO2002020645A2 WO2002020645A2 (en) 2002-03-14
WO2002020645A3 true WO2002020645A3 (en) 2002-07-18

Family

ID=24640505

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/026457 WO2002020645A2 (en) 2000-08-24 2001-08-24 Polymer matrices prepared by supercritical fluid processing techniques

Country Status (3)

Country Link
US (1) US6521258B1 (en)
AU (1) AU2001285255A1 (en)
WO (1) WO2002020645A2 (en)

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US9486558B2 (en) 2003-03-27 2016-11-08 Locate Therapeutics Limited Porous matrix

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US7129322B2 (en) * 2001-10-24 2006-10-31 Seikisui Chemicals Co., Ltd. Method for producing polymer alloy polymer alloy formed article transparent formed article and optical film
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US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
US20090062909A1 (en) * 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
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CA2996768C (en) 2006-04-26 2020-12-08 Micell Technologies, Inc. Coatings containing multiple drugs
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US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
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Also Published As

Publication number Publication date
US6521258B1 (en) 2003-02-18
AU2001285255A1 (en) 2002-03-22
WO2002020645A2 (en) 2002-03-14

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