WO2002018921A3 - Method and system for real-time fluorescent determination of trace elements - Google Patents

Method and system for real-time fluorescent determination of trace elements Download PDF

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Publication number
WO2002018921A3
WO2002018921A3 PCT/US2001/026892 US0126892W WO0218921A3 WO 2002018921 A3 WO2002018921 A3 WO 2002018921A3 US 0126892 W US0126892 W US 0126892W WO 0218921 A3 WO0218921 A3 WO 0218921A3
Authority
WO
WIPO (PCT)
Prior art keywords
samples
real
trace elements
time fluorescent
radiation
Prior art date
Application number
PCT/US2001/026892
Other languages
French (fr)
Other versions
WO2002018921A2 (en
Inventor
Dwight Sherod Walker
Original Assignee
Glaxo Group Ltd
Dwight Sherod Walker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE60126959T priority Critical patent/DE60126959T2/en
Priority to AU8688401A priority patent/AU8688401A/en
Priority to IL15425601A priority patent/IL154256A0/en
Priority to CA002420665A priority patent/CA2420665A1/en
Priority to JP2002523593A priority patent/JP2004507759A/en
Priority to AU2001286884A priority patent/AU2001286884B2/en
Application filed by Glaxo Group Ltd, Dwight Sherod Walker filed Critical Glaxo Group Ltd
Priority to EP01966362A priority patent/EP1314021B1/en
Priority to US10/363,294 priority patent/US7277168B2/en
Publication of WO2002018921A2 publication Critical patent/WO2002018921A2/en
Publication of WO2002018921A3 publication Critical patent/WO2002018921A3/en
Priority to IL154256A priority patent/IL154256A/en
Priority to US11/531,469 priority patent/US7456952B2/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/88Investigating the presence of flaws or contamination
    • G01N21/95Investigating the presence of flaws or contamination characterised by the material or shape of the object to be examined
    • G01N21/9508Capsules; Tablets
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/02Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material
    • G01N23/04Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material
    • G01N23/043Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material using fluoroscopic examination, with visual observation or video transmission of fluoroscopic images
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0339Holders for solids, powders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N2021/845Objects on a conveyor

Abstract

A system for real-time fluorescent determination of trace elements comprising means for moving a plurality of samples (14) having at least one trace element along a sample path; means (22) for generating a plurality of incident radiation pulses of different wavelength; means for illuminating at least a respective one of the samples with at least a respective one of the radiation pulses during the movement of the samples, the radiation pulse having a suitable range of fluorescence radiation wavelengths; means (22) for detecting the resultant fluorescence emitted from each of the samples; and first control means (24) in communication with the moving means and the incident radiation generating means for synchronizing the means for illuminating each of the samples with the moving means.
PCT/US2001/026892 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements WO2002018921A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AU8688401A AU8688401A (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements
IL15425601A IL154256A0 (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements
CA002420665A CA2420665A1 (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements
JP2002523593A JP2004507759A (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescence measurement of trace elements
AU2001286884A AU2001286884B2 (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements
DE60126959T DE60126959T2 (en) 2000-08-29 2001-08-29 METHOD AND DEVICE FOR REAL-TIME FLUORESCENCE DETERMINATION OF TRACE ELEMENTS
EP01966362A EP1314021B1 (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements
US10/363,294 US7277168B2 (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements
IL154256A IL154256A (en) 2000-08-29 2003-02-03 Method and system for real-time fluorescent determination of trace elements
US11/531,469 US7456952B2 (en) 2000-08-29 2006-09-13 System for real-time fluorescent determination of trace elements

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22867300P 2000-08-29 2000-08-29
US60/228,673 2000-08-29

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10363294 A-371-Of-International 2001-08-29
US11/531,469 Continuation US7456952B2 (en) 2000-08-29 2006-09-13 System for real-time fluorescent determination of trace elements

Publications (2)

Publication Number Publication Date
WO2002018921A2 WO2002018921A2 (en) 2002-03-07
WO2002018921A3 true WO2002018921A3 (en) 2003-01-30

Family

ID=22858146

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/026892 WO2002018921A2 (en) 2000-08-29 2001-08-29 Method and system for real-time fluorescent determination of trace elements

Country Status (11)

Country Link
US (2) US7277168B2 (en)
EP (1) EP1314021B1 (en)
JP (1) JP2004507759A (en)
AT (1) ATE355516T1 (en)
AU (2) AU8688401A (en)
CA (1) CA2420665A1 (en)
DE (1) DE60126959T2 (en)
ES (1) ES2282286T3 (en)
IL (2) IL154256A0 (en)
WO (1) WO2002018921A2 (en)
ZA (1) ZA200300895B (en)

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US20040126450A1 (en) * 2002-12-30 2004-07-01 Barkans Anthony Christian Method for using electromagnetic radiation to destroy data stored on a data storage device fabricated with a conductive layer
EP1787106A1 (en) * 2004-09-10 2007-05-23 Wallac Oy Instrumentation and method adapted for optical measurement of an amplified luminescent proximity homogeneous assay
US20070257202A1 (en) * 2004-09-28 2007-11-08 Glaxo Group Limited Luminescence Sensor Apparatus and Method
US7924414B2 (en) * 2006-05-10 2011-04-12 Abb Schweiz Ag Non-hazardous bulk material analyzer system
WO2008042565A2 (en) * 2006-09-29 2008-04-10 Glaxo Group Limited Method and system for rapid phase luminescense spectroscopy analysis
US8841570B2 (en) * 2010-10-13 2014-09-23 Paramount Farms International Llc System and method for aflatoxin detection
US8967851B1 (en) 2011-01-19 2015-03-03 Kemeny Associates Spectral monitoring of ingredient blending
US20230322977A1 (en) 2022-04-11 2023-10-12 Independence Oilfield Chemicals Llc Aqueous formulations

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US5257302A (en) * 1987-08-31 1993-10-26 Ngk Insulators, Ltd. Fluorescent X-ray analyzing system
US5296911A (en) * 1992-07-16 1994-03-22 Schiapparelli Biosystems, Inc. Optical test system for a chemical analyzer
US5663997A (en) * 1995-01-27 1997-09-02 Asoma Instruments, Inc. Glass composition determination method and apparatus
WO2000006078A2 (en) * 1998-07-30 2000-02-10 Systems & Electronics Pharmaceutical pill recognition and verification system
JP2000186915A (en) * 1998-12-21 2000-07-04 Yuki Gijutsu Sogo:Kk Visual inspection method and visual inspection device in tablet blister package line

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JPS5896247A (en) * 1981-12-03 1983-06-08 Hitachi Ltd Detector for welded part
US4577110A (en) 1983-04-11 1986-03-18 Biochem Sensors, Inc. Optical apparatus and method for measuring the characteristics of materials by their fluorescence
US4866283A (en) * 1988-08-12 1989-09-12 Southwest Research Institute Optical inspection of food products
US5000569A (en) * 1988-12-28 1991-03-19 Lamb-Weston, Inc. Light reflection defect detection apparatus and method using pulsed light-emitting semiconductor devices of different wavelengths
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JPH04340445A (en) * 1991-05-17 1992-11-26 Scala Kk Method for discriminating false medicine
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US5257302A (en) * 1987-08-31 1993-10-26 Ngk Insulators, Ltd. Fluorescent X-ray analyzing system
US5085510A (en) * 1990-08-28 1992-02-04 Pfizer Inc. Pharmaceutical tablet vision inspection system
US5296911A (en) * 1992-07-16 1994-03-22 Schiapparelli Biosystems, Inc. Optical test system for a chemical analyzer
US5663997A (en) * 1995-01-27 1997-09-02 Asoma Instruments, Inc. Glass composition determination method and apparatus
WO2000006078A2 (en) * 1998-07-30 2000-02-10 Systems & Electronics Pharmaceutical pill recognition and verification system
JP2000186915A (en) * 1998-12-21 2000-07-04 Yuki Gijutsu Sogo:Kk Visual inspection method and visual inspection device in tablet blister package line

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Also Published As

Publication number Publication date
ZA200300895B (en) 2004-02-09
US20040027567A1 (en) 2004-02-12
EP1314021B1 (en) 2007-02-28
DE60126959D1 (en) 2007-04-12
CA2420665A1 (en) 2002-03-07
ATE355516T1 (en) 2006-03-15
EP1314021A2 (en) 2003-05-28
DE60126959T2 (en) 2007-11-08
IL154256A0 (en) 2003-09-17
JP2004507759A (en) 2004-03-11
ES2282286T3 (en) 2007-10-16
US7277168B2 (en) 2007-10-02
WO2002018921A2 (en) 2002-03-07
US20070091308A1 (en) 2007-04-26
IL154256A (en) 2008-11-26
AU2001286884B2 (en) 2004-12-09
US7456952B2 (en) 2008-11-25
AU8688401A (en) 2002-03-13

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