WO2002015940A3 - Solution of an oxazolidinone antibiotic drug - Google Patents
Solution of an oxazolidinone antibiotic drug Download PDFInfo
- Publication number
- WO2002015940A3 WO2002015940A3 PCT/US2001/025932 US0125932W WO0215940A3 WO 2002015940 A3 WO2002015940 A3 WO 2002015940A3 US 0125932 W US0125932 W US 0125932W WO 0215940 A3 WO0215940 A3 WO 0215940A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug
- solution
- concentration
- composition
- antibiotic drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/541—Non-condensed thiazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2003-7002424A KR20030027047A (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading |
CA002419597A CA2419597A1 (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading |
JP2002520861A JP2004506699A (en) | 2000-08-22 | 2001-08-20 | Solution composition of oxazolidinone antibiotic drug with enhanced drug loading |
NZ52415801A NZ524158A (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enchanced drug loading |
AU2001285087A AU2001285087B2 (en) | 2000-08-22 | 2001-08-20 | Solution of an oxazolidinone antibiotic drug |
BR0113363-2A BR0113363A (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading |
IL15442301A IL154423A0 (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading |
MXPA03001531A MXPA03001531A (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading. |
EP01964205A EP1311296B1 (en) | 2000-08-22 | 2001-08-20 | Solution of an oxazolidinone antibiotic drug |
DE60115910T DE60115910T2 (en) | 2000-08-22 | 2001-08-20 | Solution containing an antibiotic oxazolidinone drug |
AT01964205T ATE312627T1 (en) | 2000-08-22 | 2001-08-20 | SOLUTION CONTAINING AN OXAZOLIDINONE ANTIBIOTIC |
AU8508701A AU8508701A (en) | 2000-08-22 | 2001-08-20 | Solution composition of an oxazolidinone antibiotic drug having enhanced drug loading |
NO20030787A NO20030787L (en) | 2000-08-22 | 2003-02-19 | Dissolution composition of an antibiotic oxazolidinone drug with elevated drug content |
CY20061100332T CY1105464T1 (en) | 2000-08-22 | 2006-03-09 | SOLUTION OF AN OXAZOLIDINONE ANTIBIOTIC DRUG |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22684600P | 2000-08-22 | 2000-08-22 | |
US60/226,846 | 2000-08-22 | ||
US28534701P | 2001-04-20 | 2001-04-20 | |
US60/285,347 | 2001-04-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002015940A2 WO2002015940A2 (en) | 2002-02-28 |
WO2002015940A3 true WO2002015940A3 (en) | 2003-02-20 |
Family
ID=26920930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/025932 WO2002015940A2 (en) | 2000-08-22 | 2001-08-20 | Solution of an oxazolidinone antibiotic drug |
Country Status (20)
Country | Link |
---|---|
US (1) | US6989381B2 (en) |
EP (1) | EP1311296B1 (en) |
JP (1) | JP2004506699A (en) |
KR (1) | KR20030027047A (en) |
AR (1) | AR030470A1 (en) |
AT (1) | ATE312627T1 (en) |
AU (2) | AU8508701A (en) |
BR (1) | BR0113363A (en) |
CA (1) | CA2419597A1 (en) |
CY (1) | CY1105464T1 (en) |
DE (1) | DE60115910T2 (en) |
DK (1) | DK1311296T3 (en) |
ES (1) | ES2250461T3 (en) |
IL (1) | IL154423A0 (en) |
MX (1) | MXPA03001531A (en) |
NO (1) | NO20030787L (en) |
NZ (1) | NZ524158A (en) |
PE (1) | PE20020300A1 (en) |
PL (1) | PL365674A1 (en) |
WO (1) | WO2002015940A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6696426B2 (en) | 2000-08-22 | 2004-02-24 | Pharmacia Corporation | Preservative free ophthalmic oxazolidinone antibiotic drug delivery systems |
WO2004098592A1 (en) * | 2003-05-06 | 2004-11-18 | Senju Pharmaceutical Co. Ltd. | Composition containing oxazolidinone derivative |
DE10355461A1 (en) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Solid, high bioavailabilty oral formulations of N-substituted 5-chloro-2-thiophene-carboxamide derivative in hydrophilized form, useful for combating thrombo-embolic diseases |
SG10201406571YA (en) * | 2009-10-13 | 2014-11-27 | Melinta Therapeutics Inc | Pharmaceutical compositions |
WO2015042170A1 (en) | 2013-09-17 | 2015-03-26 | Wayne State University | Compositions and uses of combinations of dim-related indoles and selected anti-androgen compounds |
WO2018055581A1 (en) * | 2016-09-24 | 2018-03-29 | Jodas Expoim Private Limited | Stable injectable composition of oxazolidinone |
US10870646B2 (en) * | 2017-02-27 | 2020-12-22 | University Of St. Thomas | Oxazolidinones and pharmaceutical compositions thereof for treating bacterial infections, including infection of Mycobacterium tuberculosis |
CN108571074A (en) * | 2018-05-25 | 2018-09-25 | 夏念涛 | A kind of assembling type steel structure rectangle coupled column frame system and its assembly method |
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WO2000018387A2 (en) * | 1998-09-30 | 2000-04-06 | Alcon Laboratories, Inc. | Antibiotic compositions for treatment of the eye, ear and nose |
WO2001019366A1 (en) * | 1999-09-13 | 2001-03-22 | Insite Vision Incorporated | Topical treatment for prevention of ocular infections |
WO2002030395A1 (en) * | 2000-10-10 | 2002-04-18 | Pharmacia & Upjohn Company | Topical antibiotic composition for treatment of eye infection |
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US6407079B1 (en) * | 1985-07-03 | 2002-06-18 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation |
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-
2001
- 2001-08-14 PE PE2001000807A patent/PE20020300A1/en not_active Application Discontinuation
- 2001-08-20 ES ES01964205T patent/ES2250461T3/en not_active Expired - Lifetime
- 2001-08-20 US US09/933,366 patent/US6989381B2/en not_active Expired - Fee Related
- 2001-08-20 CA CA002419597A patent/CA2419597A1/en not_active Abandoned
- 2001-08-20 MX MXPA03001531A patent/MXPA03001531A/en active IP Right Grant
- 2001-08-20 IL IL15442301A patent/IL154423A0/en unknown
- 2001-08-20 AU AU8508701A patent/AU8508701A/en active Pending
- 2001-08-20 WO PCT/US2001/025932 patent/WO2002015940A2/en active IP Right Grant
- 2001-08-20 KR KR10-2003-7002424A patent/KR20030027047A/en not_active Application Discontinuation
- 2001-08-20 BR BR0113363-2A patent/BR0113363A/en not_active Application Discontinuation
- 2001-08-20 DK DK01964205T patent/DK1311296T3/en active
- 2001-08-20 AT AT01964205T patent/ATE312627T1/en not_active IP Right Cessation
- 2001-08-20 JP JP2002520861A patent/JP2004506699A/en not_active Withdrawn
- 2001-08-20 EP EP01964205A patent/EP1311296B1/en not_active Expired - Lifetime
- 2001-08-20 AU AU2001285087A patent/AU2001285087B2/en not_active Ceased
- 2001-08-20 PL PL01365674A patent/PL365674A1/en not_active Application Discontinuation
- 2001-08-20 DE DE60115910T patent/DE60115910T2/en not_active Expired - Fee Related
- 2001-08-20 NZ NZ52415801A patent/NZ524158A/en unknown
- 2001-08-22 AR ARP010104011A patent/AR030470A1/en unknown
-
2003
- 2003-02-19 NO NO20030787A patent/NO20030787L/en not_active Application Discontinuation
-
2006
- 2006-03-09 CY CY20061100332T patent/CY1105464T1/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000018387A2 (en) * | 1998-09-30 | 2000-04-06 | Alcon Laboratories, Inc. | Antibiotic compositions for treatment of the eye, ear and nose |
WO2001019366A1 (en) * | 1999-09-13 | 2001-03-22 | Insite Vision Incorporated | Topical treatment for prevention of ocular infections |
WO2002030395A1 (en) * | 2000-10-10 | 2002-04-18 | Pharmacia & Upjohn Company | Topical antibiotic composition for treatment of eye infection |
Non-Patent Citations (1)
Title |
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LOFTSSON T: "INCREASING THE CYCLODEXTRIN COMPLEXATION OF DRUGS AND DRUG BIOVAILABILITY THROUGH ADDITION OF WATER-SOLUBLE POLYMERS", PHARMAZIE, VEB VERLAG VOLK UND GESUNDHEIT. BERLIN, DD, vol. 53, no. 11, 1 November 1998 (1998-11-01), pages 733 - 740, XP000783396, ISSN: 0031-7144 * |
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ATE312627T1 (en) | 2005-12-15 |
CY1105464T1 (en) | 2010-04-28 |
KR20030027047A (en) | 2003-04-03 |
IL154423A0 (en) | 2003-09-17 |
JP2004506699A (en) | 2004-03-04 |
AU8508701A (en) | 2002-03-04 |
US6989381B2 (en) | 2006-01-24 |
ES2250461T3 (en) | 2006-04-16 |
MXPA03001531A (en) | 2003-06-24 |
PL365674A1 (en) | 2005-01-10 |
BR0113363A (en) | 2004-01-06 |
AR030470A1 (en) | 2003-08-20 |
DK1311296T3 (en) | 2006-04-18 |
DE60115910D1 (en) | 2006-01-19 |
NZ524158A (en) | 2004-12-24 |
EP1311296B1 (en) | 2005-12-14 |
NO20030787L (en) | 2003-04-03 |
CA2419597A1 (en) | 2002-02-28 |
PE20020300A1 (en) | 2002-05-10 |
US20020068720A1 (en) | 2002-06-06 |
EP1311296A2 (en) | 2003-05-21 |
NO20030787D0 (en) | 2003-02-19 |
AU2001285087B2 (en) | 2006-08-03 |
DE60115910T2 (en) | 2006-08-17 |
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