WO2002014531A3 - Microarray platen - Google Patents

Microarray platen Download PDF

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Publication number
WO2002014531A3
WO2002014531A3 PCT/US2001/024994 US0124994W WO0214531A3 WO 2002014531 A3 WO2002014531 A3 WO 2002014531A3 US 0124994 W US0124994 W US 0124994W WO 0214531 A3 WO0214531 A3 WO 0214531A3
Authority
WO
WIPO (PCT)
Prior art keywords
platen
grooves
work surface
adjustment member
positioning
Prior art date
Application number
PCT/US2001/024994
Other languages
French (fr)
Other versions
WO2002014531A2 (en
Inventor
Joe Ben Bevirt
Eric J Rollins
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to AU2001281217A priority Critical patent/AU2001281217A1/en
Publication of WO2002014531A2 publication Critical patent/WO2002014531A2/en
Publication of WO2002014531A3 publication Critical patent/WO2002014531A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00533—Sheets essentially rectangular
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00689—Automatic using computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0491—Position sensing, encoding; closed-loop control
    • G01N2035/0494—Detecting or compensating piositioning errors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Jigs For Machine Tools (AREA)
  • Specific Conveyance Elements (AREA)

Abstract

The present invention provides a platen (200) for a microarray processing device to retain workpieces such as microscope slides (32) on a work surface of the platen. The platen includes a plurality of grooves (202) that are located on the work surface of the platen. Each groove has at least one restricting orifice (204). The restricting orifices are connected to a vacuum source so that the workpiece is capable of being retained on the work surface of the platen when the workpiece is positioned over one of the plurality of grooves. The grooves may be of various shapes such as rectangular, circular, oval or square. For purposes of alignment and positioning, the platen may also rest on a plurality of positioning devices. Each positioning device includes an outer adjustment member and an inner bolt. The outer adjustment member is pivotally mounted to the inner bolt such that the outer adjustement member is allowed to rotate about the inner adjustment member and force the platen in the vertical direction.
PCT/US2001/024994 2000-08-11 2001-08-09 Microarray platen WO2002014531A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281217A AU2001281217A1 (en) 2000-08-11 2001-08-09 Microarray platen

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US22433700P 2000-08-11 2000-08-11
US22433800P 2000-08-11 2000-08-11
US22433500P 2000-08-11 2000-08-11
US22433600P 2000-08-11 2000-08-11
US60/224,336 2000-08-11
US60/224,338 2000-08-11
US60/224,335 2000-08-11
US60/224,337 2000-08-11
US63973200A 2000-08-15 2000-08-15
US63973300A 2000-08-15 2000-08-15
US63973100A 2000-08-15 2000-08-15
US63973400A 2000-08-15 2000-08-15
US09/639,731 2000-08-15
US09/638,733 2000-08-15
US09/639,734 2000-08-15
US09/639,732 2000-08-15

Publications (2)

Publication Number Publication Date
WO2002014531A2 WO2002014531A2 (en) 2002-02-21
WO2002014531A3 true WO2002014531A3 (en) 2003-01-16

Family

ID=27575221

Family Applications (4)

Application Number Title Priority Date Filing Date
PCT/US2001/024844 WO2002013967A2 (en) 2000-08-11 2001-08-08 Microarray alignment mechanism
PCT/US2001/024850 WO2002014877A2 (en) 2000-08-11 2001-08-08 Microarray retrieval unit
PCT/US2001/024994 WO2002014531A2 (en) 2000-08-11 2001-08-09 Microarray platen
PCT/US2001/024996 WO2002013968A2 (en) 2000-08-11 2001-08-09 Microarray placer unit

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/US2001/024844 WO2002013967A2 (en) 2000-08-11 2001-08-08 Microarray alignment mechanism
PCT/US2001/024850 WO2002014877A2 (en) 2000-08-11 2001-08-08 Microarray retrieval unit

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2001/024996 WO2002013968A2 (en) 2000-08-11 2001-08-09 Microarray placer unit

Country Status (2)

Country Link
AU (4) AU2001281182A1 (en)
WO (4) WO2002013967A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6955788B2 (en) 2001-09-07 2005-10-18 Affymetrix, Inc. Apparatus and method for aligning microarray printing head
DE10261533A1 (en) * 2002-12-23 2004-07-15 BioChip Technologies GmbH Gesellschaft für Entwicklung und Produktion von Detektionssystemen Holder for slide onto which droplet array is deposited, includes locating stops on long side of slide support surface, used in conjunction with clamping system
EP1652580A1 (en) * 2004-10-29 2006-05-03 Affymetrix, Inc. High throughput microarray, package assembly and methods of manufacturing arrays
HUP0700404A2 (en) * 2007-06-08 2009-03-30 3D Histech Kft Catch frame for slide and slide feeding unit
US10509216B2 (en) 2012-12-26 2019-12-17 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
CN102010817B (en) * 2010-08-06 2013-05-22 博奥生物有限公司 Chip automatic loading device of microarray chip scanner
JP6080860B2 (en) * 2011-11-16 2017-02-15 ライカ・バイオシステムズ・メルボルン・プロプライエタリー・リミテッドＬｅｉｃａ Ｂｉｏｓｙｓｔｅｍｓ Ｍｅｌｂｏｕｒｎｅ Ｐｔｙ Ｌｔｄ Automated system and method for processing tissue samples on slides
CN104053979B (en) 2011-11-16 2018-03-27 莱卡生物系统墨尔本私人有限公司 For handling the equipment and automated process of the biological specimen being arranged on substrate
US11274998B2 (en) 2012-12-26 2022-03-15 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
US9989448B2 (en) 2012-12-26 2018-06-05 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
AU2013369398B2 (en) * 2012-12-26 2017-04-20 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
CN104007274B (en) * 2014-06-04 2016-02-03 上海宏莘科技发展有限公司 Folder off-type digital-code type fully-automatic intelligent sampler
DE102016125691B4 (en) 2016-12-23 2018-10-25 Leica Microsystems Cms Gmbh Holder for microscope slide, microscope and method for controlling a microscope
JP7126809B2 (en) * 2017-04-13 2022-08-29 浜松ホトニクス株式会社 Image acquisition device and image acquisition method

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US4336765A (en) * 1981-06-12 1982-06-29 Coughlin Vincent D Vacuum work piece holder
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US5324012A (en) * 1991-07-16 1994-06-28 Nikon Corporation Holding apparatus for holding an article such as a semiconductor wafer
US5534073A (en) * 1992-09-07 1996-07-09 Mitsubishi Denki Kabushiki Kaisha Semiconductor producing apparatus comprising wafer vacuum chucking device
US5671910A (en) * 1992-05-06 1997-09-30 James C. Carne Vacuum plates
US5707051A (en) * 1993-08-13 1998-01-13 Kabushiki Kaisha Toshiba Wafer stage apparatus for attracting and holding semiconductor wafer
US5953590A (en) * 1996-11-26 1999-09-14 Micron Technology, Inc. Method and apparatus to hold integrated circuit chips onto a chuck and to simultaneously remove multiple integrated circuit chips from a cutting chuck

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Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4336765A (en) * 1981-06-12 1982-06-29 Coughlin Vincent D Vacuum work piece holder
DE3210528A1 (en) * 1982-03-23 1983-10-13 Krauss U. Reichert Gmbh + Co Kg Spezialmaschinenfabrik, 7012 Fellbach Table for the handling and processing of flat material, in particular table for cutting material to size
US5324012A (en) * 1991-07-16 1994-06-28 Nikon Corporation Holding apparatus for holding an article such as a semiconductor wafer
US5671910A (en) * 1992-05-06 1997-09-30 James C. Carne Vacuum plates
US5534073A (en) * 1992-09-07 1996-07-09 Mitsubishi Denki Kabushiki Kaisha Semiconductor producing apparatus comprising wafer vacuum chucking device
US5707051A (en) * 1993-08-13 1998-01-13 Kabushiki Kaisha Toshiba Wafer stage apparatus for attracting and holding semiconductor wafer
US5953590A (en) * 1996-11-26 1999-09-14 Micron Technology, Inc. Method and apparatus to hold integrated circuit chips onto a chuck and to simultaneously remove multiple integrated circuit chips from a cutting chuck

Also Published As

Publication number Publication date
WO2002013968A3 (en) 2003-01-16
WO2002013967A2 (en) 2002-02-21
WO2002013967A3 (en) 2002-08-08
WO2002014877A3 (en) 2003-01-03
WO2002014531A2 (en) 2002-02-21
AU2001279251A1 (en) 2002-02-25
AU2001281217A1 (en) 2002-02-25
AU2001281179A1 (en) 2002-02-25
WO2002013968A2 (en) 2002-02-21
AU2001281182A1 (en) 2002-02-25
WO2002014877A2 (en) 2002-02-21

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