WO2002005866A3 - Deployment system for myocardial cellular material - Google Patents

Deployment system for myocardial cellular material Download PDF

Info

Publication number
WO2002005866A3
WO2002005866A3 PCT/US2001/022029 US0122029W WO0205866A3 WO 2002005866 A3 WO2002005866 A3 WO 2002005866A3 US 0122029 W US0122029 W US 0122029W WO 0205866 A3 WO0205866 A3 WO 0205866A3
Authority
WO
WIPO (PCT)
Prior art keywords
needle assembly
cellular material
deployment system
guiding catheter
lumen
Prior art date
Application number
PCT/US2001/022029
Other languages
French (fr)
Other versions
WO2002005866A2 (en
Inventor
Howard J Leonhardt
Robert D Lashinski
Original Assignee
Bioheart Inc
Howard J Leonhardt
Robert D Lashinski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioheart Inc, Howard J Leonhardt, Robert D Lashinski filed Critical Bioheart Inc
Priority to US10/332,737 priority Critical patent/US7686799B2/en
Priority to EP01952692A priority patent/EP1301228B1/en
Priority to AU2001273421A priority patent/AU2001273421A1/en
Priority to DE60134982T priority patent/DE60134982D1/en
Publication of WO2002005866A2 publication Critical patent/WO2002005866A2/en
Publication of WO2002005866A3 publication Critical patent/WO2002005866A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082—Catheter tip comprising a tool
    • A61M25/0084—Catheter tip comprising a tool being one or more injection needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238—Type of minimally invasive operation
    • A61B2017/00243—Type of minimally invasive operation cardiac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082—Catheter tip comprising a tool
    • A61M25/0084—Catheter tip comprising a tool being one or more injection needles
    • A61M2025/0085—Multiple injection needles protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
    • A61M2025/0086—Multiple injection needles protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip the needles having bent tips, i.e. the needle distal tips are angled in relation to the longitudinal axis of the catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082—Catheter tip comprising a tool
    • A61M25/0084—Catheter tip comprising a tool being one or more injection needles
    • A61M2025/0087—Multiple injection needles protruding laterally from the distal tip

Abstract

A catheter-based deployment system for deploying cellular material (22) into the heart muscle (25). The deployment system includes a guiding catheter (19) and a needle assembly (31) capable of sliding within the guiding catheter. The needle assembly (31) terminates in a tip (34) having at least one side with an opening (43) in communication with a lumen (20) disposed within the needle assembly (31). Once the guiding catheter (19) is positioned, the needle assembly (31) is advanced until the tip (34) penetrates the muscle wall (25). At a predetermined depth the cellular material (22) may be deployed into the muscle wall (25) via a push rod (46) disposed through the lumen of the needle assembly (31).
PCT/US2001/022029 2000-07-13 2001-07-13 Deployment system for myocardial cellular material WO2002005866A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US10/332,737 US7686799B2 (en) 2000-07-13 2001-07-13 Deployment system for myocardial cellular material
EP01952692A EP1301228B1 (en) 2000-07-13 2001-07-13 Deployment system for myocardial cellular material
AU2001273421A AU2001273421A1 (en) 2000-07-13 2001-07-13 Deployment system for myocardial cellular material
DE60134982T DE60134982D1 (en) 2000-07-13 2001-07-13 INTRODUCTION SYSTEM FOR MYOCARDIAL, CELLULAR MATERIAL

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US21797700P 2000-07-13 2000-07-13
US21797600P 2000-07-13 2000-07-13
US60/217,977 2000-07-13
US60/217,976 2000-07-13
US25351400P 2000-11-28 2000-11-28
US60/253,514 2000-11-28

Publications (2)

Publication Number Publication Date
WO2002005866A2 WO2002005866A2 (en) 2002-01-24
WO2002005866A3 true WO2002005866A3 (en) 2002-05-23

Family

ID=27396479

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/022029 WO2002005866A2 (en) 2000-07-13 2001-07-13 Deployment system for myocardial cellular material

Country Status (7)

Country Link
US (1) US7686799B2 (en)
EP (1) EP1301228B1 (en)
AT (1) ATE401920T1 (en)
AU (1) AU2001273421A1 (en)
DE (1) DE60134982D1 (en)
ES (1) ES2309079T3 (en)
WO (1) WO2002005866A2 (en)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6120520A (en) 1997-05-27 2000-09-19 Angiotrax, Inc. Apparatus and methods for stimulating revascularization and/or tissue growth
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
US6051008A (en) 1996-12-02 2000-04-18 Angiotrax, Inc. Apparatus having stabilization members for percutaneously performing surgery and methods of use
US7087064B1 (en) * 2002-10-15 2006-08-08 Advanced Cardiovascular Systems, Inc. Apparatuses and methods for heart valve repair
US7335213B1 (en) 2002-11-15 2008-02-26 Abbott Cardiovascular Systems Inc. Apparatus and methods for heart valve repair
US9149602B2 (en) 2005-04-22 2015-10-06 Advanced Cardiovascular Systems, Inc. Dual needle delivery system
US7485143B2 (en) * 2002-11-15 2009-02-03 Abbott Cardiovascular Systems Inc. Apparatuses and methods for heart valve repair
US6945978B1 (en) * 2002-11-15 2005-09-20 Advanced Cardiovascular Systems, Inc. Heart valve catheter
US8187324B2 (en) 2002-11-15 2012-05-29 Advanced Cardiovascular Systems, Inc. Telescoping apparatus for delivering and adjusting a medical device in a vessel
US7981152B1 (en) 2004-12-10 2011-07-19 Advanced Cardiovascular Systems, Inc. Vascular delivery system for accessing and delivering devices into coronary sinus and other vascular sites
US7404824B1 (en) * 2002-11-15 2008-07-29 Advanced Cardiovascular Systems, Inc. Valve aptation assist device
US8308708B2 (en) * 2003-07-15 2012-11-13 Abbott Cardiovascular Systems Inc. Deployment system for myocardial cellular material
ITRM20030376A1 (en) 2003-07-31 2005-02-01 Univ Roma PROCEDURE FOR THE ISOLATION AND EXPANSION OF CARDIOC STAMIN CELLS FROM BIOPSIA.
US7998112B2 (en) 2003-09-30 2011-08-16 Abbott Cardiovascular Systems Inc. Deflectable catheter assembly and method of making same
US7632262B2 (en) * 2004-07-19 2009-12-15 Nexeon Medical Systems, Inc. Systems and methods for atraumatic implantation of bio-active agents
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
US20090012525A1 (en) * 2005-09-01 2009-01-08 Eric Buehlmann Devices and systems for delivering bone fill material
US20070282254A1 (en) * 2006-05-16 2007-12-06 Mina Chow Needle devices and methods
AU2007292923B2 (en) * 2006-09-08 2013-10-03 Cardiopolymers, Inc. Intramyocardial patterning for global cardiac resizing and reshaping
US10335131B2 (en) * 2006-10-23 2019-07-02 Intuitive Surgical Operations, Inc. Methods for preventing tissue migration
US20110034867A1 (en) * 2007-03-22 2011-02-10 Jacques Guyette Microthread delivery system
WO2008154033A2 (en) * 2007-06-11 2008-12-18 Symphony Medical, Inc. Cardiac patterning for improving diastolic function
CA2692038A1 (en) * 2007-06-15 2008-12-24 Lifescan, Inc. Flexible cannula or medical device conduit
US7935082B2 (en) 2007-09-27 2011-05-03 Biosense Webster, Inc. Control handle with device advancing mechanism
DE602008002201D1 (en) 2007-10-29 2010-09-30 Lifescan Inc Flexible cannula made of a Nitinol strip coated with a flexible hose for medical applications
DE102008013854A1 (en) * 2008-03-12 2009-09-24 Siemens Aktiengesellschaft Catheter and associated medical examination and treatment facility
US8801665B2 (en) * 2008-04-10 2014-08-12 Henry Ford Health System Apparatus and method for controlled depth of injection into myocardial tissue
US20100112696A1 (en) * 2008-11-03 2010-05-06 Baxter International Inc. Apparatus And Methods For Processing Tissue To Release Cells
US8309343B2 (en) * 2008-12-01 2012-11-13 Baxter International Inc. Apparatus and method for processing biological material
BE1018521A5 (en) 2009-04-29 2011-02-01 Cardio3 Biosciences Sa INJECTION CATHETER FOR DELIVERING A THERAPEUTIC AGENT IN A SUBSTRATE.
US9554830B2 (en) 2010-02-25 2017-01-31 Mayo Foundation For Medical Education And Research Delivering drugs to desired locations within a mammal
US9845457B2 (en) 2010-04-30 2017-12-19 Cedars-Sinai Medical Center Maintenance of genomic stability in cultured stem cells
US9249392B2 (en) 2010-04-30 2016-02-02 Cedars-Sinai Medical Center Methods and compositions for maintaining genomic stability in cultured stem cells
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
US20130197468A1 (en) * 2012-01-26 2013-08-01 Carnegie Mellon University Device for Intramyocardial Delivery
US9107693B2 (en) * 2012-04-16 2015-08-18 Pacesetter, Inc. Apparatus and method for pericardial access
JP2015521054A (en) 2012-06-05 2015-07-27 カプリコール，インコーポレイテッド Optimized methods for generating cardiac stem cells from heart tissue and their use in cardiac therapy
CA2881394A1 (en) 2012-08-13 2014-02-20 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
CN105992816B (en) 2013-11-16 2018-04-17 泰尔茂比司特公司 Cell amplification in bioreactor
JP6783143B2 (en) 2014-03-25 2020-11-11 テルモ ビーシーティー、インコーポレーテッド Passive replenishment of medium
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
CA2962444C (en) 2014-10-03 2023-09-05 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
EP3380017A4 (en) 2015-11-25 2019-11-27 Talon Medical, LLC Tissue engagement devices, systems, and methods
EP3402543B1 (en) 2016-01-11 2021-09-08 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
US10646644B2 (en) * 2016-03-15 2020-05-12 CalXStars Business Accelerator, Inc. Stimulator, pump and composition
US11110274B2 (en) 2016-03-15 2021-09-07 Leonhardt Ventures Llc System and method for treating inflammation
US11052247B2 (en) 2016-03-15 2021-07-06 Leonhardt Ventures Llc Skin treatment system
US10695563B2 (en) 2016-03-28 2020-06-30 CalXStars Business Accelerator, Inc. Orthodontic treatment
US11185691B2 (en) 2016-03-15 2021-11-30 Leonhardt Ventures Llc Tumor therapy
US11691007B2 (en) 2016-03-15 2023-07-04 Leonhardt Ventures Llc Bioelectric OPG treatment of cancer
US11849910B2 (en) 2016-03-15 2023-12-26 Valvublator Inc. Methods, systems, and devices for heart valve decalcification, regeneration, and repair
US10960206B2 (en) 2016-03-15 2021-03-30 Leonhardt Ventures Llc Bioelectric stimulator
US11167141B2 (en) 2016-03-15 2021-11-09 Leonhardt Ventures Llc Bioelectric blood pressure management
WO2017172854A1 (en) 2016-03-29 2017-10-05 George Pins Compositions and methods for wound healing
WO2017210652A1 (en) 2016-06-03 2017-12-07 Cedars-Sinai Medical Center Cdc-derived exosomes for treatment of ventricular tachyarrythmias
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
EP3515459A4 (en) 2016-09-20 2020-08-05 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656842A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
EP3612191A4 (en) 2017-04-19 2020-12-30 Cedars-Sinai Medical Center Methods and compositions for treating skeletal muscular dystrophy
US11660355B2 (en) 2017-12-20 2023-05-30 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
US11471686B2 (en) 2019-03-13 2022-10-18 Leonhardt Ventures Llc Klotho modulation
US11446488B2 (en) 2019-03-13 2022-09-20 Leonhardt Ventures Llc Kidney treatment
USD957646S1 (en) 2019-08-29 2022-07-12 OrthodontiCell, Inc. Dental mouthpiece

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5419777A (en) * 1994-03-10 1995-05-30 Bavaria Medizin Technologie Gmbh Catheter for injecting a fluid or medicine

Family Cites Families (220)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US598059A (en) * 1898-01-25 Gas-lam p
US2749909A (en) 1956-06-12 Biopsy knife
US1162901A (en) 1915-10-08 1915-12-07 Edward B Cantey Instrument for cutting cores from solid substances.
US2001638A (en) 1932-11-14 1935-05-14 Res Foundation Inc Surgical needle
US2710000A (en) 1952-02-19 1955-06-07 Cromer Jeremiah Keith Cutting instrument
US3120845A (en) 1961-02-20 1964-02-11 David B Horner Self-powered surgical drill
US3477423A (en) 1967-01-09 1969-11-11 Baxter Laboratories Inc Biopsy instrument
GB1235321A (en) 1968-01-30 1971-06-09 Nat Res Dev Improvements in or relating to drills for clearing obstructions
US3557794A (en) 1968-07-30 1971-01-26 Us Air Force Arterial dilation device
US3692020A (en) 1971-04-29 1972-09-19 Robert J Schied Rotary punch for excising uniform diopsy specimens
US3780246A (en) 1972-08-22 1973-12-18 Black & Decker Mfg Co Hand-operated tool with switch actuator having three-position lock-off assembly
US4207874A (en) 1978-03-27 1980-06-17 Choy Daniel S J Laser tunnelling device
US4186750A (en) 1978-04-19 1980-02-05 The Kendall Company Position testing device
US4356826A (en) 1979-05-09 1982-11-02 Olympus Optical Co., Ltd. Stabbing apparatus for diagnosis of living body
US4299230A (en) 1979-05-09 1981-11-10 Olympus Optical Co., Ltd. Stabbing apparatus for diagnosis of living body
IT7922984V0 (en) 1979-10-29 1979-10-29 Star Utensili Elett PORTABLE ELECTRIC TOOL WITH PERFECTED CONTROLS.
US4362161A (en) 1980-10-27 1982-12-07 Codman & Shurtleff, Inc. Cranial drill
US4578061A (en) * 1980-10-28 1986-03-25 Lemelson Jerome H Injection catheter and method
US4461305A (en) 1981-09-04 1984-07-24 Cibley Leonard J Automated biopsy device
US4479896A (en) 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
US4582056A (en) 1983-03-30 1986-04-15 Mccorkle Jr Charles E Endocardial lead extraction apparatus and method
US4576162A (en) 1983-03-30 1986-03-18 Mccorkle Charles E Apparatus and method for separation of scar tissue in venous pathway
DE3341117C2 (en) 1983-11-12 1986-02-06 Josef 7512 Rheinstetten Lindenberg Biopsy cannula
US4600014A (en) 1984-02-10 1986-07-15 Dan Beraha Transrectal prostate biopsy device and method
US5135531A (en) 1984-05-14 1992-08-04 Surgical Systems & Instruments, Inc. Guided atherectomy system
US5443443A (en) 1984-05-14 1995-08-22 Surgical Systems & Instruments, Inc. Atherectomy system
US4596574A (en) 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
USRE33258E (en) 1984-07-23 1990-07-10 Surgical Dynamics Inc. Irrigating, cutting and aspirating system for percutaneous surgery
US4578057A (en) 1984-08-31 1986-03-25 Cordis Corporation Ventricular right angle connector and system
US4957742A (en) 1984-11-29 1990-09-18 Regents Of The University Of Minnesota Method for promoting hair growth
US4702261A (en) 1985-07-03 1987-10-27 Sherwood Medical Company Biopsy device and method
US4790812A (en) 1985-11-15 1988-12-13 Hawkins Jr Irvin F Apparatus and method for removing a target object from a body passsageway
US4646738A (en) 1985-12-05 1987-03-03 Concept, Inc. Rotary surgical tool
US5000185A (en) 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
US4729763A (en) 1986-06-06 1988-03-08 Henrie Rodney A Catheter for removing occlusive material
US4792327A (en) 1986-09-15 1988-12-20 Barry Swartz Lipectomy cannula
WO1988003035A2 (en) * 1986-10-31 1988-05-05 Titan Medical, Inc. Applicator with splittable cannula for placement of flexible catheter
US4976710A (en) 1987-01-28 1990-12-11 Mackin Robert A Working well balloon method
US4923462A (en) 1987-03-17 1990-05-08 Cordis Corporation Catheter system having a small diameter rotatable drive member
US4850354A (en) 1987-08-13 1989-07-25 Baxter Travenol Laboratories, Inc. Surgical cutting instrument
US4813930A (en) 1987-10-13 1989-03-21 Dimed, Inc. Angioplasty guiding catheters and methods for performing angioplasty
US4788975B1 (en) 1987-11-05 1999-03-02 Trimedyne Inc Control system and method for improved laser angioplasty
US4895166A (en) 1987-11-23 1990-01-23 Interventional Technologies, Inc. Rotatable cutter for the lumen of a blood vesel
DE3906301A1 (en) 1988-04-28 1989-12-14 Olympus Optical Co Surgical resection instrument
US5195988A (en) 1988-05-26 1993-03-23 Haaga John R Medical needle with removable sheath
US4917102A (en) 1988-09-14 1990-04-17 Advanced Cardiovascular Systems, Inc. Guidewire assembly with steerable adjustable tip
US4898577A (en) 1988-09-28 1990-02-06 Advanced Cardiovascular Systems, Inc. Guiding cathether with controllable distal tip
US4964854A (en) * 1989-01-23 1990-10-23 Luther Medical Products, Inc. Intravascular catheter assembly incorporating needle tip shielding cap
US4985028A (en) 1989-08-30 1991-01-15 Angeion Corporation Catheter
US5104393A (en) 1989-08-30 1992-04-14 Angelase, Inc. Catheter
US4997431A (en) 1989-08-30 1991-03-05 Angeion Corporation Catheter
US5226909A (en) 1989-09-12 1993-07-13 Devices For Vascular Intervention, Inc. Atherectomy device having helical blade and blade guide
US5030201A (en) 1989-11-24 1991-07-09 Aubrey Palestrant Expandable atherectomy catheter device
US5152744A (en) 1990-02-07 1992-10-06 Smith & Nephew Dyonics Surgical instrument
EP0448857A1 (en) 1990-03-27 1991-10-02 Jong-Khing Huang An apparatus of a spinning type of resectoscope for prostatectomy
US5269785A (en) 1990-06-28 1993-12-14 Bonutti Peter M Apparatus and method for tissue removal
US5125924A (en) 1990-09-24 1992-06-30 Laser Engineering, Inc. Heart-synchronized vacuum-assisted pulsed laser system and method
US5125926A (en) 1990-09-24 1992-06-30 Laser Engineering, Inc. Heart-synchronized pulsed laser system
US5242460A (en) 1990-10-25 1993-09-07 Devices For Vascular Intervention, Inc. Atherectomy catheter having axially-disposed cutting edge
US5389096A (en) 1990-12-18 1995-02-14 Advanced Cardiovascular Systems System and method for percutaneous myocardial revascularization
US5505725A (en) 1990-10-30 1996-04-09 Cardiogenesis Corporation Shapeable optical fiber apparatus
US5093877A (en) 1990-10-30 1992-03-03 Advanced Cardiovascular Systems Optical fiber lasing apparatus lens
US5885272A (en) 1990-10-30 1999-03-23 Aita; Michael System and method for percutaneous myocardial revascularization
US5380316A (en) 1990-12-18 1995-01-10 Advanced Cardiovascular Systems, Inc. Method for intra-operative myocardial device revascularization
US5465717A (en) 1991-02-15 1995-11-14 Cardiac Pathways Corporation Apparatus and Method for ventricular mapping and ablation
US5415166A (en) 1991-02-15 1995-05-16 Cardiac Pathways Corporation Endocardial mapping apparatus and cylindrical semiconductor device mounting structure for use therewith and method
US5224951A (en) 1991-02-19 1993-07-06 Dexide, Inc. Surgical trocar and spike assembly
US5339799A (en) 1991-04-23 1994-08-23 Olympus Optical Co., Ltd. Medical system for reproducing a state of contact of the treatment section in the operation unit
NZ272209A (en) 1991-05-01 2001-02-23 Univ Columbia Myocardial revascularisation of the heart by a laser
US5285795A (en) 1991-09-12 1994-02-15 Surgical Dynamics, Inc. Percutaneous discectomy system having a bendable discectomy probe and a steerable cannula
US5263959A (en) 1991-10-21 1993-11-23 Cathco, Inc. Dottering auger catheter system and method
US5238005A (en) 1991-11-18 1993-08-24 Intelliwire, Inc. Steerable catheter guidewire
WO1993012825A1 (en) 1991-12-20 1993-07-08 Abbott Laboratories Automated drug infusion system with autopriming
ATE150953T1 (en) 1992-01-13 1997-04-15 Schneider Usa Inc SURGICAL CUTTING INSTRUMENT
DE69225812T2 (en) 1992-01-13 1998-10-01 Schneider Usa Inc CUTTING DEVICE FOR ATHEREECTOMY CATHETER
US5222501A (en) 1992-01-31 1993-06-29 Duke University Methods for the diagnosis and ablation treatment of ventricular tachycardia
GR920100104A (en) 1992-03-13 1993-11-30 Christodoulos I Stefanadis Temporary luminal stent for the support of the vascular wall.
SE9201413L (en) 1992-04-30 1993-10-31 Stiftelsen Foer Medicinsk Tekn Preparation and Methods for Apheresis Preparation of Platelet Concentrate with Significantly Extended Durability
US5324284A (en) 1992-06-05 1994-06-28 Cardiac Pathways, Inc. Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method
US5281218A (en) 1992-06-05 1994-01-25 Cardiac Pathways Corporation Catheter having needle electrode for radiofrequency ablation
US5279567A (en) 1992-07-02 1994-01-18 Conmed Corporation Trocar and tube with pressure signal
US5613972A (en) 1992-07-15 1997-03-25 The University Of Miami Surgical cutting heads with curled cutting wings
US5342393A (en) 1992-08-27 1994-08-30 Duke University Method and device for vascular repair
US5447533A (en) 1992-09-03 1995-09-05 Pacesetter, Inc. Implantable stimulation lead having an advanceable therapeutic drug delivery system
US5411514A (en) 1992-09-30 1995-05-02 Linvatec Corporation Bendable variable angle rotating shaver
US5429144A (en) 1992-10-30 1995-07-04 Wilk; Peter J. Coronary artery by-pass method
CA2102084A1 (en) 1992-11-09 1994-05-10 Howard C. Topel Surgical cutting instrument for coring tissue affixed thereto
US5330466A (en) 1992-12-01 1994-07-19 Cardiac Pathways Corporation Control mechanism and system and method for steering distal extremity of a flexible elongate member
US5389073A (en) 1992-12-01 1995-02-14 Cardiac Pathways Corporation Steerable catheter with adjustable bend location
US5584842A (en) 1992-12-02 1996-12-17 Intramed Laboratories, Inc. Valvulotome and method of using
US5383884A (en) 1992-12-04 1995-01-24 American Biomed, Inc. Spinal disc surgical instrument
US5273051A (en) 1993-03-16 1993-12-28 Wilk Peter J Method and associated device for obtaining a biopsy of tissues of an internal organ
US5354310A (en) 1993-03-22 1994-10-11 Cordis Corporation Expandable temporary graft
CA2121861A1 (en) 1993-04-23 1994-10-24 William D. Fox Mechanical morcellator
WO1994027670A1 (en) 1993-06-02 1994-12-08 Cardiac Pathways Corporation Catheter having tip with fixation means
US5571088A (en) 1993-07-01 1996-11-05 Boston Scientific Corporation Ablation catheters
US5527325A (en) 1993-07-09 1996-06-18 Device For Vascular Intervention, Inc. Atherectomy catheter and method
US5921982A (en) 1993-07-30 1999-07-13 Lesh; Michael D. Systems and methods for ablating body tissue
US5392917A (en) 1993-08-03 1995-02-28 Ethicon, Inc. Easy open 1-2-3 instrumentation package
US5336237A (en) 1993-08-25 1994-08-09 Devices For Vascular Intervention, Inc. Removal of tissue from within a body cavity
US5454791A (en) 1993-09-07 1995-10-03 United States Surgical Corporation Trocar with tissue penetration pressure indicator
US5470316A (en) 1993-09-07 1995-11-28 United States Surgical Corporation Body tissue penetrating device having a vacuum indicator
US5425376A (en) * 1993-09-08 1995-06-20 Sofamor Danek Properties, Inc. Method and apparatus for obtaining a biopsy sample
US5409000A (en) 1993-09-14 1995-04-25 Cardiac Pathways Corporation Endocardial mapping and ablation system utilizing separately controlled steerable ablation catheter with ultrasonic imaging capabilities and method
US5379772A (en) 1993-09-14 1995-01-10 Intelliwire, Inc. Flexible elongate device having forward looking ultrasonic imaging
US5464404A (en) 1993-09-20 1995-11-07 Abela Laser Systems, Inc. Cardiac ablation catheters and method
US5415654A (en) 1993-10-05 1995-05-16 S.L.T. Japan Co., Ltd. Laser balloon catheter apparatus
US5439474A (en) 1993-10-08 1995-08-08 Li Medical Technologies, Inc. Morcellator system
US5456689A (en) 1993-10-13 1995-10-10 Arnold J. Kresch Method and device for tissue resection
US5575810A (en) 1993-10-15 1996-11-19 Ep Technologies, Inc. Composite structures and methods for ablating tissue to form complex lesion patterns in the treatment of cardiac conditions and the like
US5575766A (en) 1993-11-03 1996-11-19 Daig Corporation Process for the nonsurgical mapping and treatment of atrial arrhythmia using catheters guided by shaped guiding introducers
US5640955A (en) 1995-02-14 1997-06-24 Daig Corporation Guiding introducers for use in the treatment of accessory pathways around the mitral valve using a retrograde approach
US5722400A (en) 1995-02-16 1998-03-03 Daig Corporation Guiding introducers for use in the treatment of left ventricular tachycardia
US5366468A (en) 1993-11-09 1994-11-22 Linvatec Corporation Double bladed surgical router having aspiration ports within flutes
US5421821A (en) 1993-11-12 1995-06-06 Marlow Surgical Technologies, Inc. Verres needle system and method
US5492119A (en) 1993-12-22 1996-02-20 Heart Rhythm Technologies, Inc. Catheter tip stabilizing apparatus
CA2143560C (en) 1994-03-02 2007-01-16 Mark Fogelberg Sterile occlusion fasteners and instrument and method for their placement
DE59409469D1 (en) 1994-03-23 2000-09-07 Erbe Elektromedizin Multifunctional instrument for ultrasound surgery
US5464395A (en) 1994-04-05 1995-11-07 Faxon; David P. Catheter for delivering therapeutic and/or diagnostic agents to the tissue surrounding a bodily passageway
SE9401267D0 (en) 1994-04-14 1994-04-14 Siemens Elema Ab The electrode device
US5743870A (en) 1994-05-09 1998-04-28 Somnus Medical Technologies, Inc. Ablation apparatus and system for removal of soft palate tissue
US5547469A (en) 1994-05-13 1996-08-20 Boston Scientific Corporation Apparatus for performing diagnostic and therapeutic modalities in the biliary tree
DE4420232A1 (en) 1994-06-07 1995-12-14 Robert Waltereit Penetration depth checking device for hollow needle or probe inserted in human or animal patient
US5656339A (en) 1994-06-20 1997-08-12 U.S. Philips Corporation Method of and arrangement for applying a fluid to a surface using a vibrating needle
US5643253A (en) 1995-06-06 1997-07-01 Rare Earth Medical, Inc. Phototherapy apparatus with integral stopper device
US5569284A (en) 1994-09-23 1996-10-29 United States Surgical Corporation Morcellator
JP3614943B2 (en) 1994-09-29 2005-01-26 オリンパス株式会社 Endoscopic puncture needle
US5562694A (en) 1994-10-11 1996-10-08 Lasersurge, Inc. Morcellator
US5591159A (en) 1994-11-09 1997-01-07 Taheri; Syde A. Transcavitary myocardial perfusion apparatus
DE4441327C1 (en) 1994-11-22 1995-11-09 Inst Pflanzengenetik & Kultur Embryonic heart muscle cells, their production and their use
US5611803A (en) 1994-12-22 1997-03-18 Urohealth Systems, Inc. Tissue segmentation device
US5551427A (en) * 1995-02-13 1996-09-03 Altman; Peter A. Implantable device for the effective elimination of cardiac arrhythmogenic sites
US5569254A (en) 1995-04-12 1996-10-29 Midas Rex Pneumatic Tools, Inc. Surgical resection tool having an irrigation, lighting, suction and vision attachment
US5651781A (en) 1995-04-20 1997-07-29 Grace-Wells Technology Partners No. 1, L.P. Surgical cutting instrument
AU5558096A (en) 1995-05-01 1996-11-21 Medtronic Cardiorhythm Dual curve ablation catheter and method
US5606974A (en) 1995-05-02 1997-03-04 Heart Rhythm Technologies, Inc. Catheter having ultrasonic device
US6322548B1 (en) 1995-05-10 2001-11-27 Eclipse Surgical Technologies Delivery catheter system for heart chamber
US6251104B1 (en) 1995-05-10 2001-06-26 Eclipse Surgical Technologies, Inc. Guiding catheter system for ablating heart tissue
US5658263A (en) 1995-05-18 1997-08-19 Cordis Corporation Multisegmented guiding catheter for use in medical catheter systems
US5571133A (en) 1995-06-01 1996-11-05 Yoon; Inbae Penetrating instrument with sequential indication of entry into anatomical cavities
US6224584B1 (en) 1997-01-14 2001-05-01 Eclipse Surgical Technologies, Inc. Therapeutic and diagnostic agent delivery
US5797870A (en) 1995-06-07 1998-08-25 Indiana University Foundation Pericardial delivery of therapeutic and diagnostic agents
US5840059A (en) 1995-06-07 1998-11-24 Cardiogenesis Corporation Therapeutic and diagnostic agent delivery
US5609621A (en) 1995-08-04 1997-03-11 Medtronic, Inc. Right ventricular outflow tract defibrillation lead
US5702412A (en) 1995-10-03 1997-12-30 Cedars-Sinai Medical Center Method and devices for performing vascular anastomosis
CA2234389A1 (en) 1995-10-13 1997-04-17 Transvascular, Inc. A device, system and method for interstitial transvascular intervention
US6283951B1 (en) 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US5569178A (en) 1995-10-20 1996-10-29 Henley; Julian L. Power assisted suction lipectomy device
US5709697A (en) 1995-11-22 1998-01-20 United States Surgical Corporation Apparatus and method for removing tissue
EP0871512A1 (en) 1995-12-22 1998-10-21 Localmed, Inc. Localized intravascular delivery of growth factors for promotion of angiogenesis
IL116685A (en) 1996-01-05 2000-07-16 Vascular Technologies Ltd Blood vessel entry indicator
US5688234A (en) 1996-01-26 1997-11-18 Cardiometrics Inc. Apparatus and method for the treatment of thrombotic occlusions in vessels
US5810836A (en) * 1996-03-04 1998-09-22 Myocardial Stents, Inc. Device and method for trans myocardial revascularization (TMR)
US5834418A (en) 1996-03-20 1998-11-10 Theratechnologies, Inc. Process for the preparation of platelet growth factors extract
US5725521A (en) 1996-03-29 1998-03-10 Eclipse Surgical Technologies, Inc. Depth stop apparatus and method for laser-assisted transmyocardial revascularization and other surgical applications
US5782823A (en) 1996-04-05 1998-07-21 Eclipse Surgical Technologies, Inc. Laser device for transmyocardial revascularization procedures including means for enabling a formation of a pilot hole in the epicardium
US5980545A (en) 1996-05-13 1999-11-09 United States Surgical Corporation Coring device and method
US5649911A (en) 1996-05-17 1997-07-22 Indiana University Foundation Intravenous catheter and delivery system
DE19621099C2 (en) 1996-05-24 1999-05-20 Sulzer Osypka Gmbh Device with a catheter and a needle that can be inserted into the heart wall from the inside as a high-frequency electrode
US5746713A (en) 1996-06-06 1998-05-05 Hood; Larry Phacoemulsification needle
US5662124A (en) 1996-06-19 1997-09-02 Wilk Patent Development Corp. Coronary artery by-pass method
US5662671A (en) 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries
WO1998002150A1 (en) * 1996-07-17 1998-01-22 Medtronic, Inc. System for genetically treating cardiac conduction disturbances
US5857995A (en) 1996-08-15 1999-01-12 Surgical Dynamics, Inc. Multiple bladed surgical cutting device removably connected to a rotary drive element
US5976164A (en) 1996-09-13 1999-11-02 Eclipse Surgical Technologies, Inc. Method and apparatus for myocardial revascularization and/or biopsy of the heart
US5871495A (en) 1996-09-13 1999-02-16 Eclipse Surgical Technologies, Inc. Method and apparatus for mechanical transmyocardial revascularization of the heart
US5830210A (en) 1996-10-21 1998-11-03 Plc Medical Systems, Inc. Catheter navigation apparatus
US6030377A (en) * 1996-10-21 2000-02-29 Plc Medical Systems, Inc. Percutaneous transmyocardial revascularization marking system
US5893848A (en) 1996-10-24 1999-04-13 Plc Medical Systems, Inc. Gauging system for monitoring channel depth in percutaneous endocardial revascularization
US6096036A (en) 1998-05-05 2000-08-01 Cardiac Pacemakers, Inc. Steerable catheter with preformed distal shape and method for use
US5873366A (en) 1996-11-07 1999-02-23 Chim; Nicholas Method for transmyocardial revascularization
US5971993A (en) 1996-11-07 1999-10-26 Myocardial Stents, Inc. System for delivery of a trans myocardial device to a heart wall
US6120520A (en) 1997-05-27 2000-09-19 Angiotrax, Inc. Apparatus and methods for stimulating revascularization and/or tissue growth
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
US6051008A (en) 1996-12-02 2000-04-18 Angiotrax, Inc. Apparatus having stabilization members for percutaneously performing surgery and methods of use
US5910150A (en) 1996-12-02 1999-06-08 Angiotrax, Inc. Apparatus for performing surgery
US5944716A (en) 1996-12-09 1999-08-31 Scimed Life Systems, Inc. Radio frequency transmyocardial revascularization corer
US5724975A (en) 1996-12-12 1998-03-10 Plc Medical Systems, Inc. Ultrasonic detection system for transmyocardial revascularization
US5807384A (en) 1996-12-20 1998-09-15 Eclipse Surgical Technologies, Inc. Transmyocardial revascularization (TMR) enhanced treatment for coronary artery disease
CA2225521C (en) 1996-12-27 2004-04-06 Eclipse Surgical Technologies, Inc. Laser assisted drug delivery apparatus
US5906594A (en) 1997-01-08 1999-05-25 Symbiosis Corporation Endoscopic infusion needle having dual distal stops
US5846225A (en) 1997-02-19 1998-12-08 Cornell Research Foundation, Inc. Gene transfer therapy delivery device and method
US5730741A (en) 1997-02-07 1998-03-24 Eclipse Surgical Technologies, Inc. Guided spiral catheter
US5968059A (en) 1997-03-06 1999-10-19 Scimed Life Systems, Inc. Transmyocardial revascularization catheter and method
US6045565A (en) 1997-11-04 2000-04-04 Scimed Life Systems, Inc. Percutaneous myocardial revascularization growth factor mediums and method
US5938632A (en) 1997-03-06 1999-08-17 Scimed Life Systems, Inc. Radiofrequency transmyocardial revascularization apparatus and method
US6093177A (en) 1997-03-07 2000-07-25 Cardiogenesis Corporation Catheter with flexible intermediate section
US5876373A (en) 1997-04-04 1999-03-02 Eclipse Surgical Technologies, Inc. Steerable catheter
US6024703A (en) 1997-05-07 2000-02-15 Eclipse Surgical Technologies, Inc. Ultrasound device for axial ranging
US5951567A (en) 1997-07-24 1999-09-14 Cardiogenesis Corporation Introducer for channel forming device
US6004302A (en) * 1997-08-28 1999-12-21 Brierley; Lawrence A. Cannula
US5964757A (en) 1997-09-05 1999-10-12 Cordis Webster, Inc. Steerable direct myocardial revascularization catheter
US6179809B1 (en) 1997-09-24 2001-01-30 Eclipse Surgical Technologies, Inc. Drug delivery catheter with tip alignment
US6106520A (en) 1997-09-30 2000-08-22 Hearten Medical, Inc. Endocardial device for producing reversible damage to heart tissue
US6238389B1 (en) 1997-09-30 2001-05-29 Boston Scientific Corporation Deflectable interstitial ablation device
US6056743A (en) 1997-11-04 2000-05-02 Scimed Life Systems, Inc. Percutaneous myocardial revascularization device and method
US5885276A (en) 1997-12-02 1999-03-23 Galil Medical Ltd. Method and device for transmyocardial cryo revascularization
US6066126A (en) 1997-12-18 2000-05-23 Medtronic, Inc. Precurved, dual curve cardiac introducer sheath
ES2293473T3 (en) 1998-02-05 2008-03-16 Biosense Webster, Inc. INTRACARDIAC ADMINISTRATION OF FARMACO.
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US6165164A (en) 1999-03-29 2000-12-26 Cordis Corporation Catheter for injecting therapeutic and diagnostic agents
US6905476B2 (en) 1998-06-04 2005-06-14 Biosense Webster, Inc. Catheter with injection needle
US6102887A (en) * 1998-08-11 2000-08-15 Biocardia, Inc. Catheter drug delivery system and method for use
US6432126B1 (en) * 1998-09-30 2002-08-13 C.R. Bard, Inc. Flexible vascular inducing implants
US6251079B1 (en) 1998-09-30 2001-06-26 C. R. Bard, Inc. Transthoracic drug delivery device
US6045530A (en) 1998-10-14 2000-04-04 Heyer-Schulte Neurocare Inc. Adjustable angle catheter
US6162202A (en) 1998-10-26 2000-12-19 Sicurelli; Robert Flexible syringe needle
EP1140278B1 (en) * 1998-12-14 2004-05-19 Tre Esse Progettazione Biomedica S.r.l Catheter system for performing intramyocardiac therapeutic treatment
US6217554B1 (en) 1999-02-12 2001-04-17 Pharmaspec Corporation Methods and apparatus for delivering substances into extravascular tissue
US6546787B1 (en) 1999-03-25 2003-04-15 Regents Of The University Of Minnesota Means and method for modeling and treating specific tissue structures
US6517521B1 (en) 1999-04-22 2003-02-11 Keith K. Ly Painless perforated intradermal injection needle
US6302870B1 (en) 1999-04-29 2001-10-16 Precision Vascular Systems, Inc. Apparatus for injecting fluids into the walls of blood vessels, body cavities, and the like
US6494862B1 (en) 1999-07-13 2002-12-17 Advanced Cardiovascular Systems, Inc. Substance delivery apparatus and a method of delivering a therapeutic substance to an anatomical passageway
US6405091B1 (en) * 1999-07-20 2002-06-11 Pacesetter, Inc. Lead assembly with masked microdisk tip electrode and monolithic controlled release device
US6638233B2 (en) 1999-08-19 2003-10-28 Fox Hollow Technologies, Inc. Apparatus and methods for material capture and removal
US6613062B1 (en) 1999-10-29 2003-09-02 Medtronic, Inc. Method and apparatus for providing intra-pericardial access
WO2002083003A1 (en) 2001-04-11 2002-10-24 Clarke Dana S Tissue structure identification in advance of instrument
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
ATE363310T1 (en) 2002-09-10 2007-06-15 Becton Dickinson Co METHOD AND DEVICE FOR EPIDERMIC ADMINISTRATION OF A SUBSTANCE
US20040171933A1 (en) 2002-11-25 2004-09-02 Milton Stoller Mammography needle biopsy system and method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5419777A (en) * 1994-03-10 1995-05-30 Bavaria Medizin Technologie Gmbh Catheter for injecting a fluid or medicine

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WO2002005866A2 (en) 2002-01-24
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EP1301228A4 (en) 2006-05-31
DE60134982D1 (en) 2008-09-04
US20040010231A1 (en) 2004-01-15
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EP1301228A2 (en) 2003-04-16
US7686799B2 (en) 2010-03-30

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