Search Images Maps Play YouTube News Gmail Drive More »
Sign in
Screen reader users: click this link for accessible mode. Accessible mode has the same essential features but works better with your reader.

Patents

  1. Advanced Patent Search
Publication numberWO2001092565 A3
Publication typeApplication
Application numberPCT/EP2001/003973
Publication date6 Sep 2002
Filing date6 Apr 2001
Priority date6 Apr 2000
Also published asDE60126593D1, DE60126593T2, EP1268857A2, EP1268861A2, EP1272670A2, EP1274865A2, EP1274865B1, EP1274866A2, EP1278893A2, EP1360319A2, EP1370685A2, EP2014776A2, EP2014776A3, US7195870, US20030082609, US20030148326, US20030148327, US20030162194, US20040067491, US20040076956, US20050282157, WO2001076451A2, WO2001076451A3, WO2001076451A9, WO2001077164A2, WO2001077164A3, WO2001077164A8, WO2001077375A2, WO2001077375A3, WO2001077375A8, WO2001077376A2, WO2001077376A3, WO2001077376A8, WO2001077377A2, WO2001077377A3, WO2001077377A8, WO2001077378A2, WO2001077378A3, WO2001081622A2, WO2001081622A3, WO2001081622A8, WO2001092565A2, WO2001092565A8
Publication numberPCT/2001/3973, PCT/EP/1/003973, PCT/EP/1/03973, PCT/EP/2001/003973, PCT/EP/2001/03973, PCT/EP1/003973, PCT/EP1/03973, PCT/EP1003973, PCT/EP103973, PCT/EP2001/003973, PCT/EP2001/03973, PCT/EP2001003973, PCT/EP200103973, WO 0192565 A3, WO 0192565A3, WO 2001/092565 A3, WO 2001092565 A3, WO 2001092565A3, WO-A3-0192565, WO-A3-2001092565, WO0192565 A3, WO0192565A3, WO2001/092565A3, WO2001092565 A3, WO2001092565A3
InventorsAlexander Olek, Christian Piepenbrock, Kurt Berlin
ApplicantEpigenomics Ag, Alexander Olek, Christian Piepenbrock, Kurt Berlin
Export CitationBiBTeX, EndNote, RefMan
External Links: Patentscope, Espacenet
Diagnosis of diseases associated dna transcription by means of assessing the methylation status of genes associated with dna transcription
WO 2001092565 A3
Abstract
The present invention relates to the chemically modified genomic sequences of genes associated with DNA transcription, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genes associated with DNA transcription which are directed against the sequence, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes associated with DNA transcription.
Patent Citations
Cited PatentFiling datePublication dateApplicantTitle
WO1999028498A2 *27 Nov 199810 Jun 1999Epigenomics GmbhMethod for producing complex dna methylation fingerprints
WO1999029898A2 *4 Dec 199817 Jun 1999MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.Method for identifying nucleic acids by means of matrix-assisted laser desorption/ionisation mass spectrometry
WO2001068912A2 *15 Mar 200120 Sep 2001Epigenomics AgDiagnosis of diseases associated with tumor suppressor genes and oncogenes
WO2001077375A2 *6 Apr 200118 Oct 2001Epigenomics AgDiagnosis of diseases associated with gene regulation
WO2001077377A2 *6 Apr 200118 Oct 2001Epigenomics AgDiagnosis of diseases associated with dna replication by assessing dna methylation
US5744305 *6 Jun 199528 Apr 1998Affymetrix, Inc.Arrays of materials attached to a substrate
Non-Patent Citations
Reference
1 *BRUNK BP ET AL.: "Regulated demethylation of the myoD distal enhancer during skeletal myogenesis.", DEVELOPMENTAL BIOLOGY, vol. 177, no. 2, 1996, pages 490 - 503, XP001026536
2 *DATABASE EMBL [online] EBI; 10 October 1995 (1995-10-10), OGURA T.: "NAD+ ADP-ribosyltransferase; PADPRP-I gene; promoter", XP002187359, retrieved from HTTP://WWW.EBI.AC.UK/CGI-BIN/EMBLFETCH Database accession no. X16674
3 *DATABASE EMBL [online] EBI; 11 October 1999 (1999-10-11), BIRREN B ET AL.: "Homo sapiens clone RP11-15H13", XP002187361, retrieved from HTTP://WWW.EBI.AC.UK/CGI-BIN/EMBLFETCH Database accession no. AC011651
4 *DATABASE EMBL [online] EBI; 2 July 1999 (1999-07-02), HERZOG ET AL.: "human poly(ADP-ribose) polymerase gene, 5' end.", XP002187360, retrieved from HTTP://WWW.EBI.AC.UK/CGI-BIN/EMBLFETCH Database accession no. M60436
5 *DATABASE GENBANK [online] NCBI; 7 August 1998 (1998-08-07), CHEN B ET AL.: "Homo sapiens myogenic determining factor 3 (MYOD1) gene", XP002187358, retrieved from HTTP://WWW.NCBI.NLM.NIH.GOV/ Database accession no. AF027148
Classifications
International ClassificationA61P35/00, C07K14/46, C07K14/82, C12M1/00, G01N33/53, C12Q1/48, A61P29/00, A61P11/06, G01N37/00, A61P13/12, G01N33/483, A61P7/04, C12Q1/68, C07K14/47, G01N27/62, A61K48/00, G01N33/566, B01J19/00, A61P9/10, C12N15/09, A61K31/711
Cooperative ClassificationC12Q2600/156, C12Q2600/154, C07K14/82, C12Q1/6886, C12Q1/6883, C07K14/4703
European ClassificationC12Q1/68M6, C12Q1/68M6B, C07K14/47A1A, C07K14/82
Legal Events
DateCodeEventDescription
6 Dec 2001AKDesignated states
Kind code of ref document: A2
Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW
6 Dec 2001ALDesignated countries for regional patents
Kind code of ref document: A2
Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG
30 Jan 2002121Ep: the epo has been informed by wipo that ep was designated in this application
31 Jan 2002DFPERequest for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
2 May 2002CFPCorrected version of a pamphlet front page
30 May 2002CFPCorrected version of a pamphlet front page
25 Sep 2002WWEWipo information: entry into national phase
Ref document number: 2001969303
Country of ref document: EP
2 Jan 2003WWPWipo information: published in national office
Ref document number: 2001969303
Country of ref document: EP
21 Jan 2003WWEWipo information: entry into national phase
Ref document number: 10240453
Country of ref document: US
13 Jan 2005NENPNon-entry into the national phase in:
Ref country code: JP