WO2001091721A3 - Modified starch as a replacement for gelatin in soft gel films and capsules - Google Patents

Modified starch as a replacement for gelatin in soft gel films and capsules Download PDF

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Publication number
WO2001091721A3
WO2001091721A3 PCT/US2001/014888 US0114888W WO0191721A3 WO 2001091721 A3 WO2001091721 A3 WO 2001091721A3 US 0114888 W US0114888 W US 0114888W WO 0191721 A3 WO0191721 A3 WO 0191721A3
Authority
WO
WIPO (PCT)
Prior art keywords
gelatin
capsules
replacement
modified starch
soft gel
Prior art date
Application number
PCT/US2001/014888
Other languages
French (fr)
Other versions
WO2001091721A2 (en
Inventor
Gregory M Gilleland
Judy L Turner
Penelope A Patton
Michael D Harrison
Original Assignee
Staley Mfg Co A E
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Staley Mfg Co A E filed Critical Staley Mfg Co A E
Priority to AU2001259644A priority Critical patent/AU2001259644A1/en
Publication of WO2001091721A2 publication Critical patent/WO2001091721A2/en
Publication of WO2001091721A3 publication Critical patent/WO2001091721A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18Manufacture of films or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2303/00Characterised by the use of starch, amylose or amylopectin or of their derivatives or degradation products

Abstract

Film-forming compositions are disclosed that can comprise, on a dry solid basis, 25 to 75 percent by weight of certain starch derivatives having a DE less than about 1,25 to 75 % plasticizer, and 0.1 to 15 % hydrocolloid gum. The starch derivatives can be chemically modified starches which range in molecular weight from 100,000 to 2,000,000. These starch-based systems can completely replace gelatin in edible film-forming applications such as soft and hard gel capsules.
PCT/US2001/014888 2000-06-01 2001-05-09 Modified starch as a replacement for gelatin in soft gel films and capsules WO2001091721A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001259644A AU2001259644A1 (en) 2000-06-01 2001-05-09 Modified starch as a replacement for gelatin in soft gel films and capsules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/584,413 2000-06-01
US09/584,413 US6375981B1 (en) 2000-06-01 2000-06-01 Modified starch as a replacement for gelatin in soft gel films and capsules

Publications (2)

Publication Number Publication Date
WO2001091721A2 WO2001091721A2 (en) 2001-12-06
WO2001091721A3 true WO2001091721A3 (en) 2002-05-30

Family

ID=24337221

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/014888 WO2001091721A2 (en) 2000-06-01 2001-05-09 Modified starch as a replacement for gelatin in soft gel films and capsules

Country Status (3)

Country Link
US (1) US6375981B1 (en)
AU (1) AU2001259644A1 (en)
WO (1) WO2001091721A2 (en)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030068362A1 (en) * 1993-02-22 2003-04-10 American Bioscience, Inc. Methods and formulations for the delivery of pharmacologically active agents
BR0007787A (en) * 1999-01-29 2002-02-05 Avebe Coop Verkoop Prod Starch Composition, Use of a Process Starch Composition to Prepare a Thick Food, Food, and Confectionery
CA2271361A1 (en) * 1999-05-07 2000-11-07 Peter Taylor Edible casing film formulation
US6528088B1 (en) * 2000-06-01 2003-03-04 A. E. Staley Manufacturing Co. Highly flexible starch-based films
AU2001261318A1 (en) * 2000-06-01 2001-12-11 A.E. Staley Manufacturing Co. Highly flexible starch-based films
US6479649B1 (en) * 2000-12-13 2002-11-12 Fmc Corporation Production of carrageenan and carrageenan products
US20030070584A1 (en) 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US8309118B2 (en) 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
JP5701468B2 (en) * 2001-10-12 2015-04-15 モノソル・アールエックス・エルエルシー Thin film with uniform heterogeneity that does not self-aggregate, method for producing the same, and drug delivery system produced therefrom
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20030099691A1 (en) * 2001-11-16 2003-05-29 Susan Lydzinski Films containing starch
DE60238269D1 (en) * 2001-11-22 2010-12-23 Morishita Jintan Co Non-gelatinous capsules
US6949256B2 (en) * 2002-01-18 2005-09-27 Banner Pharmacaps, Inc. Non-gelatin capsule shell formulation
US7887838B2 (en) * 2002-01-18 2011-02-15 Banner Pharmacaps, Inc. Non-gelatin film and method and apparatus for producing same
US20030198682A1 (en) * 2002-02-12 2003-10-23 Gruber James V. Composition and method for protecting labile active components during high temperature drying
US8017150B2 (en) 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
DE60316454T2 (en) * 2002-07-29 2008-06-26 Alza Corp., Mountain View METHOD AND METHOD OF FORMING THE CONTROLLED DELIVERY OF PALIPERIDONE
US6979482B2 (en) * 2002-11-08 2005-12-27 Exopack-Technology, Llc Multiwall bag with zipper and fin
US20040111275A1 (en) * 2002-11-15 2004-06-10 Kroll David B. Methods for marketing and generating revenue from edible thin films
US20040096569A1 (en) * 2002-11-15 2004-05-20 Barkalow David G. Edible film products and methods of making same
US20060134311A1 (en) * 2002-12-20 2006-06-22 Rolf Mueller Starch-based rubber-elastic confectionery
CN100356908C (en) * 2003-01-30 2007-12-26 莫诺索尔克斯有限公司 Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20040156794A1 (en) * 2003-02-11 2004-08-12 Barkalow David G. Bioerodible and bioadhesive confectionery products and methods of making same
US6969196B2 (en) * 2003-03-07 2005-11-29 Exopack-Technology, Llc Bag having reclosable seal and associated methods
GB0306736D0 (en) * 2003-03-24 2003-04-30 Nestec Sa Gelled food with a liquid centre
JP4414670B2 (en) * 2003-04-10 2010-02-10 松谷化学工業株式会社 Process for producing glucose polymer having ion exchange ability and composition containing the same
US20050013847A1 (en) * 2003-04-14 2005-01-20 Fmc Corporation Delivery systems of homogeneous, thermoreversible alginate films
US7816341B2 (en) * 2003-04-14 2010-10-19 Fmc Corporation Homogeneous, thermoreversible gel containing reduced viscosity carrageenan and products made therefrom
US20050048185A1 (en) * 2003-04-14 2005-03-03 Fmc Corporation Delivery systems of homogeneous, thermoreversible low viscosity polymannan gum films
US20050019294A1 (en) * 2003-04-14 2005-01-27 Fmc Corporation Homogeneous, thermoreversible alginate films and soft capsules made therefrom
KR20060011953A (en) * 2003-04-14 2006-02-06 에프엠씨 코포레이션 Process for making gel films
US20050008677A1 (en) * 2003-04-14 2005-01-13 Fmc Corporation Delivery system of homogeneous, thermoreversible gel film containing kappa-2 carrageenan
US20050019295A1 (en) * 2003-04-14 2005-01-27 Fmc Corporation Homogeneous, thermoreversible low viscosity polymannan gum films and soft capsules made therefrom
US6939210B2 (en) * 2003-05-02 2005-09-06 Applied Materials, Inc. Slurry delivery arm
US20050008736A1 (en) * 2003-05-19 2005-01-13 Egan Philip A. Non-fluorocarbon high temperature packaging having flexible starch-based film and methods of producing same
CN102670568A (en) * 2003-05-28 2012-09-19 莫诺索尔克斯有限公司 Polyethylene oxide-based films and drug delivery systems made therefrom
US20040241294A1 (en) * 2003-05-31 2004-12-02 Barabolak Roman M. Edible films including aspartame and methods of making same
GB0314832D0 (en) * 2003-06-25 2003-07-30 Phoqus Pharmaceuticals Ltd Production of capsule shells and capsules
US7134978B2 (en) * 2003-07-28 2006-11-14 Sagittarius Life Science Corporation Seamless BB paintball
DE50303300D1 (en) * 2003-08-22 2006-06-14 Symrise Gmbh & Co Kg Covering material for seamless capsules
US20050042331A1 (en) * 2003-08-22 2005-02-24 Billmers Robert L. Starches for reduced fat in fried foods systems
US7582341B2 (en) * 2003-10-02 2009-09-01 Exopack Technology Llc Elastomer and polyolefin resin based films and associated methods
US7083838B2 (en) * 2003-10-02 2006-08-01 Exopack, L.L.C. Elastomer and polyolefin resin based films and associated methods
WO2005104674A2 (en) 2003-11-12 2005-11-10 National Paintball Supply, Inc. Projectile, projectile core, and method of making
US20050186256A1 (en) * 2004-02-20 2005-08-25 Dihel Deborah L. Dissolvable film comprising an active ingredient and method of manufacture
US7494667B2 (en) * 2004-03-02 2009-02-24 Brunob Ii B.V. Blends of different acyl gellan gums and starch
US20050196437A1 (en) * 2004-03-02 2005-09-08 Bednarz Christina A. Hard capsules
JP4374497B2 (en) * 2004-04-20 2009-12-02 松谷化学工業株式会社 Edible film
US6998374B2 (en) * 2004-06-14 2006-02-14 Carl Niedbala Composition and method for cleaning gelatin encapsulated products comprising a non-volatile silicone/volatile silicone mixture
US20060011089A1 (en) * 2004-06-17 2006-01-19 Edward Hensel Paintball having reduced drag
US20080194337A1 (en) * 2004-10-25 2008-08-14 Edward Hensel Hunting Game Having Human And Electromechanical Players
US7905181B2 (en) * 2005-02-05 2011-03-15 Ciesiun Paul M Bioluminescent paintball
US8479656B2 (en) * 2005-02-05 2013-07-09 Hydro-Caps, Llc Water based paintball and method for fabricating water based paintballs
US20060289518A1 (en) * 2005-05-20 2006-12-28 Exopack-Technology, Llc Microwave cooking package for food products and associated methods
US20060289519A1 (en) * 2005-05-20 2006-12-28 Exopack-Technology, Llc Microwave cooking package for food products and associated methods
US20070034827A1 (en) * 2005-12-02 2007-02-15 Zhixin Li Blends of gelling and non-gelling starches with gellan gums and plasticizer
US8282539B2 (en) * 2008-12-22 2012-10-09 Exopack, Llc Multi-layered bags and methods of manufacturing the same
US20090324143A1 (en) * 2005-08-19 2009-12-31 Exopack, Llc. Bags having composite structures and related methods
US20070047852A1 (en) * 2005-08-29 2007-03-01 Exopack-Technology, Llc Grease-resistant pinch-bottom bag, adhesive closure for bag, and related methods
US20070047853A1 (en) * 2005-08-29 2007-03-01 Exopack-Technology, Llc Grease-resistant bag having adhesive closure, adhesive closure for bag, and related methods
US7569529B2 (en) 2005-09-07 2009-08-04 The Procter & Gamble Company Method of using fabric care compositions to achieve a synergistic odor benefit
CA2572937A1 (en) * 2005-12-27 2007-06-27 Christopher Black Paintball and method of manufacture
WO2007081655A2 (en) * 2006-01-05 2007-07-19 Tate & Lyle Ingredients Americas, Inc. Extrudable food composition
US20070161942A1 (en) * 2006-01-06 2007-07-12 Pharmaphil Inc. Biodegradable tampon applicator and method of making
DK3095447T3 (en) 2006-02-03 2022-01-31 Opko Renal Llc TREATMENT OF VITAMIN D INSUFFICIENTS AND DEFICIENCY WITH 25-HYDROXYVITAMIN D2 AND 25-HYDROXYVITAMIN D3
WO2007121318A2 (en) * 2006-04-12 2007-10-25 Emisphere Technologies, Inc. Formulations for delivering insulin
US20070281065A1 (en) * 2006-06-06 2007-12-06 Modliszewski James J Kappa-2 carrageenan composition and products made therefrom
PL2679228T3 (en) 2006-06-21 2018-07-31 Opko Ireland Global Holdings, Ltd. Therapy using vitamin D repletion agent and vitamin D hormone replacement agent
US8574624B2 (en) * 2006-11-17 2013-11-05 Corn Products Development, Inc. Highly inhibited starch fillers for films and capsules
US20090087468A1 (en) * 2007-03-28 2009-04-02 Serena Stephenson Semi-Rigid Gel Article For Disinfecting A Surface
EP3225243A1 (en) 2007-04-25 2017-10-04 Opko Renal, LLC Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
CN104257667B (en) 2007-04-25 2019-06-04 欧普科Ip 控股Ii 有限公司 Treat vitamin d insufficiency and shortage, secondary hyperparathyroidism and vitamin D-responsive diseases method and composition
PL2481400T3 (en) 2007-04-25 2015-04-30 Opko Ip Holdings Ii Inc Oral controlled release compositions comprising vitamin D compound and waxy carrier
US20090238925A1 (en) * 2007-12-18 2009-09-24 Shiji Shen Starch and Amphiphilic Surfactant or Particulate Emulsion for Paper Coating Applications
CN102046019B (en) * 2008-04-02 2013-09-18 帝斯曼知识产权资产管理有限公司 Gum confections
ES2954932T3 (en) 2008-04-02 2023-11-27 Eirgen Pharma Ltd Useful methods, compositions, uses and kits for vitamin D deficiency and related disorders
US9056697B2 (en) * 2008-12-15 2015-06-16 Exopack, Llc Multi-layered bags and methods of manufacturing the same
JP4797211B2 (en) * 2009-02-05 2011-10-19 キャタレント・ジャパン株式会社 Film forming composition for soft capsule
CH700543A2 (en) 2009-03-03 2010-09-15 Innogel Ag Film based on starch.
EP2243381A1 (en) 2009-04-24 2010-10-27 Mars, Incorporated Edible composition
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
TR201904204T4 (en) * 2009-09-10 2019-04-22 Dupont Nutrition Usa Inc Jointless alginate capsules.
US8747562B2 (en) * 2009-10-09 2014-06-10 Philip Morris Usa Inc. Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release
US8604399B2 (en) * 2009-10-19 2013-12-10 Exopack, Llc Microwavable bags for use with liquid oil and related methods
CN105796530A (en) 2010-03-29 2016-07-27 赛特克罗公司 Methods and compositions for reducing parathyroid levels
US8974826B2 (en) 2010-06-10 2015-03-10 Monosol Rx, Llc Nanoparticle film delivery systems
TW201215334A (en) * 2010-06-29 2012-04-16 Tate & Amp Lyle Ingredients Americas Llc Hydroxypropyl substituted starches as source of soluble fiber
CN103228269B (en) * 2010-08-04 2015-06-17 R·P·舍勒科技有限责任公司 Film-forming composition for soft capsules
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
CN102167845A (en) * 2010-12-09 2011-08-31 楼仲平 Method for preparing degradable biomass material and straw
EP2688551A1 (en) * 2011-03-22 2014-01-29 Nordbloom Ltd A composition and method
KR101847947B1 (en) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 Stabilized modified release vitamin d formulation
US20160051478A1 (en) * 2013-03-29 2016-02-25 Roquette Freres Film-forming compostions for the film-coating of solid forms
BR112015028255B1 (en) * 2013-05-21 2021-06-22 Cargill, Incorporated AQUEOUS COMPOSITION, METHOD FOR THE PRODUCTION OF AN AQUEOUS COMPOSITION, BINDING COMPOSITION, PAPER COATING COMPOSITION AND PAPER COATING COMPOSITION
JP5769760B2 (en) * 2013-06-25 2015-08-26 アール.ピー. シェーラー テクノロジーズ エルエルシー Shell forming composition for soft capsule and soft capsule
PH12014000076A1 (en) 2013-07-01 2015-09-07 Priscila F Kimes Improved processes in the preparation of coconut meat based composition and films
CN103554552B (en) 2013-10-26 2014-09-17 中山市凯博思淀粉材料科技有限公司 Preparation process of starch self-reinforced composite material for capsule articles
CN103520133B (en) * 2013-10-26 2015-02-04 中山市凯博思淀粉材料科技有限公司 Preparation method of starch-based soft capsules
CN103893771B (en) * 2014-04-21 2015-08-26 湖南尔康制药股份有限公司 A kind of film-forming composition for the production of starch material soft capsule and preparation method thereof
CN104059248B (en) * 2014-06-27 2016-08-24 江南大学 A kind of by adding the method that hydrophilic colloid improves starch base edible package film properties
EP3193925A2 (en) 2014-08-07 2017-07-26 OPKO Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin d
CN104257874A (en) * 2014-09-28 2015-01-07 通化市佳俊生物电子有限公司 Patch for treating hyperplasia of mammary glands and medical application of potatoes
US10184765B1 (en) * 2015-04-21 2019-01-22 Briana Gardell Throwable paint balls and method of manufacture
WO2017021533A1 (en) * 2015-08-06 2017-02-09 Roquette Freres Film-forming compositions based on starchy material and articles obtained thereof
CN105166885A (en) * 2015-08-07 2015-12-23 江南大学 Conjugated linoleic acid embedded microcapsule preparation method
KR101675438B1 (en) * 2015-12-18 2016-11-11 김문구 Composition for preparing soft capsule shell
CN105694118A (en) * 2016-01-29 2016-06-22 上海盈美机电工程有限公司 Novel lightly crosslinked-starch succinate-based empty capsule and preparation method thereof
CN105646951B (en) * 2016-03-03 2018-11-20 武汉市九合生物技术有限公司 The preparation method of functional solvable edible composite membrane
MX2018011820A (en) 2016-03-28 2019-01-24 Opko Ireland Global Holdings Ltd Methods of vitamin d treatment.
EP3452023A1 (en) 2016-05-05 2019-03-13 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
EP3360544A1 (en) * 2017-02-08 2018-08-15 Roquette Freres Film-forming compositions for hard capsule shells and hard capsule shells obtained thereof
WO2019169195A1 (en) * 2018-03-02 2019-09-06 Captek Softgel International, Inc Soft gel compositions and capsules made from the same
CN111116949A (en) * 2018-10-31 2020-05-08 齐鲁工业大学 Preparation method of double-enzyme modified composite edible film with slow digestion characteristic
CN110075081A (en) * 2019-06-12 2019-08-02 江苏艾兰得营养品有限公司 A kind of soft capsule and preparation method thereof and purposes
CN113121889B (en) * 2019-12-30 2022-10-21 仙乐健康科技股份有限公司 Starch film-forming composition and application thereof in plant soft capsules
US11560439B2 (en) * 2020-04-24 2023-01-24 Hunan Er-Kang Pharmaceutical Co., Ltd. Hydroxypropyl starch for preparing empty capsules and hydroxypropyl starch-based soft capsules
KR20230173712A (en) 2021-04-22 2023-12-27 씨비 바이오파마, 인크. Oral delivery of oligonucleotides
WO2024064875A1 (en) * 2022-09-23 2024-03-28 Cargill, Incorporated Natural based carbomer replacement

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4009291A (en) * 1974-03-25 1977-02-22 General Foods Corporation Cold water soluble stable bulked starch
JPH054914A (en) * 1991-06-27 1993-01-14 Asahi Chem Ind Co Ltd Capsule improved in adhesion
US5451673A (en) * 1993-04-23 1995-09-19 The United States Of America As Represented By The Secretary Of Agriculture Films fabricated from mixtures of pectin and starch
WO2000010538A1 (en) * 1998-08-25 2000-03-02 Banner Pharmacaps, Inc. Non-gelatin substitutes for oral delivery capsules, their composition and process of manufacture
FR2783832A1 (en) * 1998-09-30 2000-03-31 Warner Lambert Co Compositions for manufacture of pharmaceutical capsules comprise hydroxy propylated starch and hydrocolloid plus cation hardening system
JP2000116339A (en) * 1998-08-13 2000-04-25 Itoo Kaigai Jigyo Kk Production of edible film
WO2001003677A1 (en) * 1999-07-07 2001-01-18 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
EP1103254A1 (en) * 1999-11-19 2001-05-30 Greither, Peter Process to manufacture starch-containing shaped bodies,mass containing homogenized starch and device to manufacture soft capsules

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499962A (en) 1967-08-24 1970-03-10 Nat Starch Chem Corp Encapsulation of water insoluble materials
US3865603A (en) 1972-07-17 1975-02-11 Nat Starch Chem Corp Modified starch-extended gelatin compositions
US3956173A (en) 1974-07-05 1976-05-11 Hercules Incorporated Preparation of gels based on carrageenan
US4026986A (en) 1975-05-22 1977-05-31 The Dow Chemical Company Capsule shell
DE3529694A1 (en) 1985-08-20 1987-02-26 Scherer Gmbh R P GELATINE CAPSULES AND METHOD FOR THEIR PRODUCTION
US4795642A (en) 1986-05-01 1989-01-03 Pharmacaps, Inc. Gelatin-encapsulated controlled-release composition
US4935243A (en) 1988-12-19 1990-06-19 Pharmacaps, Inc. Chewable, edible soft gelatin capsule
US5089307A (en) 1989-05-23 1992-02-18 Mitsubishi Rayon Co., Ltd. Edible film and method of making same
CA2020895C (en) 1989-07-18 2004-02-17 Jean-Pierre Sachetto Polymer base blend compositions containing destructurized starch
GB9017800D0 (en) 1990-08-14 1990-09-26 Unilever Plc Moisture barrier and its preparation
EP0559827B1 (en) 1990-11-28 1997-08-27 R.P. Scherer Corporation High amylose starch substituted gelatin capsules
EP0547551B1 (en) 1991-12-16 1997-11-05 National Starch and Chemical Investment Holding Corporation Edible films
WO1993020110A1 (en) 1992-03-31 1993-10-14 Parke-Davis & Company Esterified starch composition
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
NZ244796A (en) 1992-08-18 1995-05-26 Scherer Corp R P Capsule shell of soft gelatin contains a medicament and has a removable tab
US5342626A (en) 1993-04-27 1994-08-30 Merck & Co., Inc. Composition and process for gelatin-free soft capsules
GB9313329D0 (en) 1993-06-28 1993-08-11 Scherer Ltd R P Softgel capsule shell compositions
US5393054A (en) 1994-03-09 1995-02-28 Zap Paintball Corporation Paint ball
US5756123A (en) 1994-12-01 1998-05-26 Japan Elanco Co., Ltd. Capsule shell
US5932639A (en) 1996-05-06 1999-08-03 National Starch And Chemical Investment Holding Corporation Maltodextrin-based adhesives
US5726008A (en) 1996-09-18 1998-03-10 Eastman Kodak Company Photographic elements with improved vehicles
US5976586A (en) 1997-03-10 1999-11-02 Lawrence Foods Glaze composition with vegetable gums
US6210709B1 (en) 1999-03-24 2001-04-03 Elementis Specialties, Inc. Flexible gelatin free encapsulation material useful for pharmaceuticals, paint balls and other formulations

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4009291A (en) * 1974-03-25 1977-02-22 General Foods Corporation Cold water soluble stable bulked starch
JPH054914A (en) * 1991-06-27 1993-01-14 Asahi Chem Ind Co Ltd Capsule improved in adhesion
US5451673A (en) * 1993-04-23 1995-09-19 The United States Of America As Represented By The Secretary Of Agriculture Films fabricated from mixtures of pectin and starch
JP2000116339A (en) * 1998-08-13 2000-04-25 Itoo Kaigai Jigyo Kk Production of edible film
WO2000010538A1 (en) * 1998-08-25 2000-03-02 Banner Pharmacaps, Inc. Non-gelatin substitutes for oral delivery capsules, their composition and process of manufacture
FR2783832A1 (en) * 1998-09-30 2000-03-31 Warner Lambert Co Compositions for manufacture of pharmaceutical capsules comprise hydroxy propylated starch and hydrocolloid plus cation hardening system
WO2001003677A1 (en) * 1999-07-07 2001-01-18 R.P. Scherer Technologies, Inc. Film forming compositions comprising modified starches and iota-carrageenan and methods for manufacturing soft capsules using same
EP1103254A1 (en) * 1999-11-19 2001-05-30 Greither, Peter Process to manufacture starch-containing shaped bodies,mass containing homogenized starch and device to manufacture soft capsules

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199307, Derwent World Patents Index; AN 1993-055171 *
DATABASE WPI Week 200032, Derwent World Patents Index; AN 2000-369392 *
PATENT ABSTRACTS OF JAPAN vol. 17, no. 266 (C - 1062) 25 May 1993 (1993-05-25) *
PATENT ABSTRACTS OF JAPAN vol. 2000, no. 07 29 September 2000 (2000-09-29) *

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