WO2001090147A3 - Long wavelength engineered fluorescent proteins - Google Patents

Long wavelength engineered fluorescent proteins Download PDF

Info

Publication number
WO2001090147A3
WO2001090147A3 PCT/US2001/016149 US0116149W WO0190147A3 WO 2001090147 A3 WO2001090147 A3 WO 2001090147A3 US 0116149 W US0116149 W US 0116149W WO 0190147 A3 WO0190147 A3 WO 0190147A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluorescent proteins
long wavelength
engineered fluorescent
wavelength engineered
proteins
Prior art date
Application number
PCT/US2001/016149
Other languages
French (fr)
Other versions
WO2001090147A2 (en
Inventor
Rebekka Wachter
S James Remington
Original Assignee
Oregon State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon State filed Critical Oregon State
Priority to EP01937550A priority Critical patent/EP1285065B1/en
Priority to AU2001263269A priority patent/AU2001263269A1/en
Priority to CA2408302A priority patent/CA2408302C/en
Priority to JP2001586334A priority patent/JP4427222B2/en
Priority to DE60114804T priority patent/DE60114804T2/en
Priority to AT01937550T priority patent/ATE309356T1/en
Publication of WO2001090147A2 publication Critical patent/WO2001090147A2/en
Publication of WO2001090147A3 publication Critical patent/WO2001090147A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Engineered fluorescent proteins, nucleic acids encoding them and methods of use.
PCT/US2001/016149 2000-05-19 2001-05-17 Long wavelength engineered fluorescent proteins WO2001090147A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP01937550A EP1285065B1 (en) 2000-05-19 2001-05-17 Long wavelength engineered fluorescent proteins
AU2001263269A AU2001263269A1 (en) 2000-05-19 2001-05-17 Long wavelength engineered fluorescent proteins
CA2408302A CA2408302C (en) 2000-05-19 2001-05-17 Long wavelength engineered fluorescent proteins
JP2001586334A JP4427222B2 (en) 2000-05-19 2001-05-17 Modified fluorescent protein with long wavelength
DE60114804T DE60114804T2 (en) 2000-05-19 2001-05-17 CONSTRUCTED FLUORESCENCE PROTEINS WITH LONG WAVELENGTH
AT01937550T ATE309356T1 (en) 2000-05-19 2001-05-17 DESIGNED FLUORESCENT PROTEINS WITH LONG WAVELENGTHS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/575,847 US6593135B2 (en) 1996-08-16 2000-05-19 Long wavelength engineered fluorescent proteins
US09/575,847 2000-05-19

Publications (2)

Publication Number Publication Date
WO2001090147A2 WO2001090147A2 (en) 2001-11-29
WO2001090147A3 true WO2001090147A3 (en) 2002-05-02

Family

ID=24301941

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016149 WO2001090147A2 (en) 2000-05-19 2001-05-17 Long wavelength engineered fluorescent proteins

Country Status (10)

Country Link
US (4) US6593135B2 (en)
EP (1) EP1285065B1 (en)
JP (1) JP4427222B2 (en)
AT (1) ATE309356T1 (en)
AU (1) AU2001263269A1 (en)
CA (1) CA2408302C (en)
DE (1) DE60114804T2 (en)
DK (1) DK1285065T3 (en)
ES (1) ES2253384T3 (en)
WO (1) WO2001090147A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803188B1 (en) * 1996-01-31 2004-10-12 The Regents Of The University Of California Tandem fluorescent protein constructs
US6593135B2 (en) * 1996-08-16 2003-07-15 The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Long wavelength engineered fluorescent proteins
US6124128A (en) 1996-08-16 2000-09-26 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
JP3829252B2 (en) * 2001-06-08 2006-10-04 独立行政法人理化学研究所 Fluorescent protein
ATE509946T1 (en) * 2002-11-12 2011-06-15 Zakrytoe Aktsionernoe Obschestvo S Evrogens FLUORESCENT PROTEINS AND CHROMOPROTEINS FROM NON-AEQUOREA HYDROZOA SPECIES AND METHOD FOR THE USE THEREOF
ES2399563T3 (en) * 2005-11-04 2013-04-02 Evrogen, Jsc Modified fluorescent green proteins and method for their use
JP4719226B2 (en) * 2006-01-26 2011-07-06 Ｎｅｃソフト株式会社 How to change the fluorescence wavelength of fluorescent protein
KR100742217B1 (en) 2006-03-13 2007-07-24 학교법인 포항공과대학교 An assay for antimicrobial peptides through ph-controlled fret
US20120122115A1 (en) * 2006-04-25 2012-05-17 Sayre Richard T Bacterial quorum sensing biosensor
US8236838B2 (en) 2008-04-21 2012-08-07 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
WO2009131957A2 (en) 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
WO2010085844A1 (en) 2009-01-29 2010-08-05 Commonwealth Scientific Industrial Research Organisation Measuring g protein coupled receptor activation
US8343976B2 (en) 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
WO2014020933A1 (en) * 2012-07-31 2014-02-06 アルバイオ株式会社 Novel fluorescent substance
US11341384B2 (en) * 2014-08-28 2022-05-24 Banctec, Incorporated Document processing system and method for associating metadata with a physical document while maintaining the integrity of its content

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996023810A1 (en) * 1994-11-10 1996-08-08 The Regents Of The University Of California Modified green fluorescenct proteins
WO1997028261A1 (en) * 1996-01-31 1997-08-07 The Regents Of The University Of California Tandem fluorescent protein constructs
WO1998006737A1 (en) * 1996-08-16 1998-02-19 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
WO1998047148A1 (en) * 1997-04-14 1998-10-22 The Regents Of The University Of California Photochromic fluorescent proteins and optical memory storage devices based on fluorescent proteins
WO1999064592A2 (en) * 1998-06-09 1999-12-16 The Regents Of The University Of California Green fluorescent proteins for measuring the ph of a biological sample

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US640374A (en) * 1899-03-02 1900-01-02 John C Fleming Reflector for electric or other lights.
US5085985A (en) * 1987-11-12 1992-02-04 Becton Dickinson & Co. Monoclonal antibodies and their use in a method for monitoring subsets of activated T cells
GB8916806D0 (en) 1989-07-22 1989-09-06 Univ Wales Medicine Modified proteins
WO1995007463A1 (en) 1993-09-10 1995-03-16 The Trustees Of Columbia University In The City Of New York Uses of green fluorescent protein
US5491084A (en) 1993-09-10 1996-02-13 The Trustees Of Columbia University In The City Of New York Uses of green-fluorescent protein
WO1995021191A1 (en) 1994-02-04 1995-08-10 William Ward Bioluminescent indicator based upon the expression of a gene for a modified green-fluorescent protein
US5795737A (en) 1994-09-19 1998-08-18 The General Hospital Corporation High level expression of proteins
US5777079A (en) 1994-11-10 1998-07-07 The Regents Of The University Of California Modified green fluorescent proteins
DE69618350T2 (en) 1995-01-31 2002-09-19 Bioimage As Soeborg A METHOD FOR DETECTING BIOLOGICALLY ACTIVE SUBSTANCES
WO1996027027A1 (en) 1995-03-02 1996-09-06 Rutgers The State University Of New Jersey Improved method for purifying green fluorescent protein
GB9504446D0 (en) 1995-03-06 1995-04-26 Medical Res Council Improvements in or relating to gene expression
US5741657A (en) * 1995-03-20 1998-04-21 The Regents Of The University Of California Fluorogenic substrates for β-lactamase and methods of use
US6342379B1 (en) * 1995-06-07 2002-01-29 The Regents Of The University Of California Detection of transmembrane potentials by optical methods
US5661035A (en) * 1995-06-07 1997-08-26 The Regents Of The University Of California Voltage sensing by fluorescence resonance energy transfer
ES2139329T3 (en) 1995-09-22 2000-02-01 Bioimage A S NEW VARIANTS OF GREEN FLUORESCENT PROTEIN, GFP.
US5874304A (en) 1996-01-18 1999-02-23 University Of Florida Research Foundation, Inc. Humanized green fluorescent protein genes and methods
US5804387A (en) 1996-02-01 1998-09-08 The Board Of Trustees Of The Leland Stanford Junior University FACS-optimized mutants of the green fluorescent protein (GFP)
US6027881A (en) 1996-05-08 2000-02-22 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Mutant Aequorea victoria fluorescent proteins having increased cellular fluorescence
US5912137A (en) * 1996-07-16 1999-06-15 The Regents Of The University Of California Assays for protein kinases using fluorescent
US5925558A (en) * 1996-07-16 1999-07-20 The Regents Of The University Of California Assays for protein kinases using fluorescent protein substrates
US6593135B2 (en) 1996-08-16 2003-07-15 The State Of Oregon, Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Long wavelength engineered fluorescent proteins
US5998204A (en) 1997-03-14 1999-12-07 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes
US6197928B1 (en) 1997-03-14 2001-03-06 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes
US6008378A (en) 1997-10-21 1999-12-28 The Regents Of The University Of California Synthetic molecules that specifically react with target sequences
US6140132A (en) 1998-06-09 2000-10-31 The Regents Of The University Of California Fluorescent protein sensors for measuring the pH of a biological sample
US6699687B1 (en) 1999-05-21 2004-03-02 The Regents Of The University Of California Circularly permuted fluorescent protein indicators
US6469154B1 (en) 1999-05-21 2002-10-22 The Regents Of The University Of California Fluorescent protein indicators
US7060793B2 (en) 1999-05-21 2006-06-13 The Regents Of The University Of California Circularly permuted fluorescent protein indicators
WO2002077011A2 (en) * 2001-03-12 2002-10-03 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon Oxidation-reduction sensitive green fluorescent protein variants

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996023810A1 (en) * 1994-11-10 1996-08-08 The Regents Of The University Of California Modified green fluorescenct proteins
WO1997028261A1 (en) * 1996-01-31 1997-08-07 The Regents Of The University Of California Tandem fluorescent protein constructs
WO1998006737A1 (en) * 1996-08-16 1998-02-19 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
WO1998047148A1 (en) * 1997-04-14 1998-10-22 The Regents Of The University Of California Photochromic fluorescent proteins and optical memory storage devices based on fluorescent proteins
WO1999064592A2 (en) * 1998-06-09 1999-12-16 The Regents Of The University Of California Green fluorescent proteins for measuring the ph of a biological sample

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
A.B. CUBITT ET AL.: "Understanding structure-function relationship in the Aequorea victoria green fluorescent protein", METHODS IN CELL BIOLOGY ; K.F. SULLIVAN AND S.A KAY, ED.;, vol. 58, 1999, 1999 Academic Press Inc., London, UK, pages 19 - 30, XP002189454, ISSN: 0-12-544169-X *
ANDERSON M T ET AL: "Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 93, no. 16, 1996, 1996, pages 8508 - 8511, XP002189455, ISSN: 0027-8424 *
ELSLIGER MARC-ANDRE ET AL: "Structural and spectral response of green fluorescent protein variants to changes in pH.", BIOCHEMISTRY, vol. 38, no. 17, 27 April 1999 (1999-04-27), pages 5296 - 5301, XP002189453, ISSN: 0006-2960 *
JAYARAMAN SUJATHA ET AL: "Mechanism and cellular applications of a green fluorescent protein-based halide sensor.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 9, 3 March 2000 (2000-03-03), pages 6047 - 6050, XP002189452, ISSN: 0021-9258 *
R.M. WACHTER AND S.J. REMINGTON: "Sensitivity of the yellow variant of green florescent protein to halides and nitrates", CURRENT BIOLOGY, vol. 9, no. 17, 1999, LONDON, UK, pages R628 - R629, XP001053344 *
WACHTER REBEKKA M ET AL: "Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein.", JOURNAL OF MOLECULAR BIOLOGY, vol. 301, no. 1, 4 August 2000 (2000-08-04), pages 157 - 171, XP002189456, ISSN: 0022-2836 *
WACHTER REBEKKA M ET AL: "Structural basis of spectral shifts in the yellow-emission variants of green fluorescent protein.", STRUCTURE (LONDON), vol. 6, no. 10, 15 October 1998 (1998-10-15), pages 1267 - 1277, XP001053367, ISSN: 0969-2126 *

Also Published As

Publication number Publication date
EP1285065B1 (en) 2005-11-09
CA2408302C (en) 2013-07-02
JP4427222B2 (en) 2010-03-03
AU2001263269A1 (en) 2001-12-03
WO2001090147A2 (en) 2001-11-29
DE60114804T2 (en) 2006-08-10
EP1285065A2 (en) 2003-02-26
US20040014128A1 (en) 2004-01-22
US20030013149A1 (en) 2003-01-16
ATE309356T1 (en) 2005-11-15
DK1285065T3 (en) 2006-03-27
US20110275107A1 (en) 2011-11-10
CA2408302A1 (en) 2001-11-29
JP2004502410A (en) 2004-01-29
US7544776B2 (en) 2009-06-09
US20100145024A1 (en) 2010-06-10
ES2253384T3 (en) 2006-06-01
DE60114804D1 (en) 2005-12-15
US6593135B2 (en) 2003-07-15
US8263412B2 (en) 2012-09-11

Similar Documents

Publication Publication Date Title
CA2232242A1 (en) Long wavelength engineered fluorescent proteins
WO2003003984A9 (en) Novel proteins and nucleic acids encoding same
AU2002236300A1 (en) Novel protein, gene encoding the same and method of using the same
WO2001090147A3 (en) Long wavelength engineered fluorescent proteins
AU2001238212A1 (en) Modified fluorescent proteins
AU2003252111A1 (en) Fluorescent proteins, nucleic acids encoding them and methods for making and using them
AU2002365909A1 (en) Glycosidases, nucleic acids encoding them and methods of making and using them
AU2002214542A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
WO2003000901A8 (en) Nucleic acids encoding protein kinases
EP1572995A3 (en) Novel proteins and nucleic acids encoding same
AU2001288363A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
WO2003025134A3 (en) mcFP ENCODING NUCLEIC ACIDS, POLYPEPTIDES, ANTIBODIES AND METHODS OF USE THEREOF
AU2002258630A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AU2002324449A1 (en) Catalases, nucleic acids encoding them and methods for making and using them
AU2002250254A1 (en) Nucleic acids, proteins, and antibodies
AU2002229060A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
WO2003040393A3 (en) Nucleic acids encoding proteases
AU2002330145A1 (en) Amidases, nucleic acids encoding them and methods for making and using them
AU2002257075A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AU2002303137A1 (en) Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
AU2001229508A1 (en) Nucleic acids, proteins, and antibodies
WO2002079390A9 (en) $i(pesudomonas) avr and hop proteins, their encoding nucleic acids, and use thereof
AU2001292273A1 (en) Novel proteins, genes encoding them and method of using the same
WO2003002606A3 (en) Nucleic acids encoding ion channels
AU9227301A (en) Novel proteins, genes encoding them and method of using the same

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2408302

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001937550

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001937550

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2001937550

Country of ref document: EP