WO2001085128A3 - Skin protectant spray compositions - Google Patents

Skin protectant spray compositions Download PDF

Info

Publication number
WO2001085128A3
WO2001085128A3 PCT/IB2001/000717 IB0100717W WO0185128A3 WO 2001085128 A3 WO2001085128 A3 WO 2001085128A3 IB 0100717 W IB0100717 W IB 0100717W WO 0185128 A3 WO0185128 A3 WO 0185128A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
skin
carrier
mineral oil
skin protectant
Prior art date
Application number
PCT/IB2001/000717
Other languages
French (fr)
Other versions
WO2001085128A2 (en
Inventor
Michael Sean Healy
Dennis George Anthony Nelson
Original Assignee
Pfizer Prod Inc
Michael Sean Healy
Dennis George Anthony Nelson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU4871501A priority Critical patent/AU4871501A/en
Application filed by Pfizer Prod Inc, Michael Sean Healy, Dennis George Anthony Nelson filed Critical Pfizer Prod Inc
Priority to DE60122879T priority patent/DE60122879T2/en
Priority to BR0110702-0A priority patent/BR0110702A/en
Priority to JP2001581783A priority patent/JP3911161B2/en
Priority to AU2001248715A priority patent/AU2001248715B2/en
Priority to US10/275,994 priority patent/US6949249B2/en
Priority to EP01921751A priority patent/EP1286652B1/en
Priority to CA002408112A priority patent/CA2408112A1/en
Priority to MXPA02010980A priority patent/MXPA02010980A/en
Publication of WO2001085128A2 publication Critical patent/WO2001085128A2/en
Publication of WO2001085128A3 publication Critical patent/WO2001085128A3/en
Priority to US11/202,127 priority patent/US20050266035A1/en
Priority to US12/336,007 priority patent/US20090317485A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585—Organosilicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/896—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate
    • A61K8/898—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients
    • A61K2800/31—Anhydrous
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Abstract

A liquid, water-repellent, substantially anhydrous, spray-pumpable skin protectant composition is disclosed. The composition is designed for spraying directly onto skin, has suitable adherence to the skin, and resists running. The composition contains one or more actives, one or more rheology modifiers, and a carrier. The rheological modifiers can be waxes and/or associative thickeners such as some forms of silica. The carrier can be mineral oil or a mineral oil replacement (e.g., isohexadecane, cyclomethicone). Film-forming components also help the composition resist running. One indication for which the composition may be formulated is diaper rash. The active ingredient for diaper rash may be dimethicone and preferably also zinc oxide.
PCT/IB2001/000717 2000-05-08 2001-04-30 Skin protectant spray compositions WO2001085128A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
US10/275,994 US6949249B2 (en) 2000-05-08 2001-04-30 Skin protectant spray compositions
DE60122879T DE60122879T2 (en) 2000-05-08 2001-04-30 SPRAY SKIN PROTECTION
BR0110702-0A BR0110702A (en) 2000-05-08 2001-04-30 Skin Protection Spray Compositions
JP2001581783A JP3911161B2 (en) 2000-05-08 2001-04-30 Spray composition for skin protection
AU2001248715A AU2001248715B2 (en) 2000-05-08 2001-04-30 Skin protectant spray compositions
AU4871501A AU4871501A (en) 2000-05-08 2001-04-30 Skin protectant spray compositions
EP01921751A EP1286652B1 (en) 2000-05-08 2001-04-30 Skin protectant spray compositions
CA002408112A CA2408112A1 (en) 2000-05-08 2001-04-30 Skin protectant spray compositions
MXPA02010980A MXPA02010980A (en) 2000-05-08 2001-04-30 Skin protectant spray compositions.
US11/202,127 US20050266035A1 (en) 2000-05-08 2005-08-11 Skin protectant spray compositions
US12/336,007 US20090317485A1 (en) 2000-05-08 2008-12-16 Skin Protectant Spray Compositions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20246700P 2000-05-08 2000-05-08
US60/202,467 2000-05-08

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/202,127 Continuation US20050266035A1 (en) 2000-05-08 2005-08-11 Skin protectant spray compositions

Publications (2)

Publication Number Publication Date
WO2001085128A2 WO2001085128A2 (en) 2001-11-15
WO2001085128A3 true WO2001085128A3 (en) 2002-04-11

Family

ID=22749979

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2001/000717 WO2001085128A2 (en) 2000-05-08 2001-04-30 Skin protectant spray compositions

Country Status (19)

Country Link
US (3) US6949249B2 (en)
EP (1) EP1286652B1 (en)
JP (1) JP3911161B2 (en)
AR (1) AR028555A1 (en)
AT (1) ATE338577T1 (en)
AU (2) AU4871501A (en)
BR (1) BR0110702A (en)
CA (1) CA2408112A1 (en)
CR (1) CR6809A (en)
DE (1) DE60122879T2 (en)
DK (1) DK1286652T3 (en)
EC (1) ECSP014064A (en)
ES (1) ES2272459T3 (en)
GT (1) GT200100080A (en)
MX (1) MXPA02010980A (en)
PA (1) PA8516601A1 (en)
SV (1) SV2003000441A (en)
WO (1) WO2001085128A2 (en)
ZA (1) ZA200209756B (en)

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US8840869B2 (en) 2002-10-25 2014-09-23 Foamix Ltd. Body cavity foams
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US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US8900553B2 (en) 2007-12-07 2014-12-02 Foamix Pharmaceuticals Ltd. Oil and liquid silicone foamable carriers and formulations
US9050253B2 (en) 2003-08-04 2015-06-09 Foamix Pharmaceuticals Ltd. Oleaginous pharmaceutical and cosmetic foam
US9072667B2 (en) 2009-07-29 2015-07-07 Foamix Pharmaceuticals Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9101662B2 (en) 2003-08-04 2015-08-11 Foamix Pharmaceuticals Ltd. Compositions with modulating agents
US9167813B2 (en) 2009-07-29 2015-10-27 Foamix Pharmaceuticals Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
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