WO2001074401A3 - Camptothecin complexes - Google Patents
Camptothecin complexes Download PDFInfo
- Publication number
- WO2001074401A3 WO2001074401A3 PCT/US2001/006829 US0106829W WO0174401A3 WO 2001074401 A3 WO2001074401 A3 WO 2001074401A3 US 0106829 W US0106829 W US 0106829W WO 0174401 A3 WO0174401 A3 WO 0174401A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- camptothecin
- disclosed
- complexes
- compositions
- inventive
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G21/00—Supporting or protective framework or housings for endless load-carriers or traction elements of belt or chain conveyors
- B65G21/10—Supporting or protective framework or housings for endless load-carriers or traction elements of belt or chain conveyors movable, or having interchangeable or relatively movable parts; Devices for moving framework or parts thereof
- B65G21/14—Supporting or protective framework or housings for endless load-carriers or traction elements of belt or chain conveyors movable, or having interchangeable or relatively movable parts; Devices for moving framework or parts thereof to allow adjustment of length or configuration of load-carrier or traction element
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01914662A EP1267936A2 (en) | 2000-03-31 | 2001-03-02 | Camptothecin complexes |
AU2001240024A AU2001240024A1 (en) | 2000-03-31 | 2001-03-02 | Camptothecin complexes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53998200A | 2000-03-31 | 2000-03-31 | |
US09/539,982 | 2000-03-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001074401A2 WO2001074401A2 (en) | 2001-10-11 |
WO2001074401A3 true WO2001074401A3 (en) | 2002-05-02 |
Family
ID=24153476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/006829 WO2001074401A2 (en) | 2000-03-31 | 2001-03-02 | Camptothecin complexes |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1267936A2 (en) |
AU (1) | AU2001240024A1 (en) |
WO (1) | WO2001074401A2 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7049322B2 (en) * | 2002-02-21 | 2006-05-23 | Supergen, Inc. | Compositions and formulations of 9-nitrocamptothecin polymorphs and methods of use therefor |
KR20120104412A (en) * | 2002-09-06 | 2012-09-20 | 인설트 테라페틱스, 인코퍼레이티드 | Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto |
EP2153821A1 (en) * | 2008-08-06 | 2010-02-17 | BioAlliance Pharma | Oral formulations of camptothecin derivatives |
US20110207760A1 (en) * | 2010-02-23 | 2011-08-25 | Valery Alakhov | Sn-38 compositions |
EP2632264B1 (en) * | 2010-10-29 | 2019-10-02 | Health Research, Inc. | Novel formulations of water-insoluble chemical compounds and methods of using a formulation of compound fl118 for cancer therapy |
WO2014055493A1 (en) | 2012-10-02 | 2014-04-10 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
CN105561406A (en) * | 2016-02-15 | 2016-05-11 | 丹阳纳瑞康纳米科技有限公司 | Intravascular stent including composite medicine coating |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0623354A1 (en) * | 1993-04-26 | 1994-11-09 | Medtronic, Inc. | Intravascular stents |
WO1999030684A1 (en) * | 1997-12-12 | 1999-06-24 | Supergen, Inc. | Local delivery of therapeutic agents |
WO1999062510A2 (en) * | 1998-06-01 | 1999-12-09 | Angiotech Pharmaceuticals, Inc. | Compositions comprising anti-microtubule agents for treating or preventing inflammatory diseases |
WO2000000238A1 (en) * | 1998-06-26 | 2000-01-06 | Quanam Medical Corporation | Topoisomerase inhibitors for prevention of restenosis |
US20010021703A1 (en) * | 1998-12-30 | 2001-09-13 | Kosak Kenneth M. | Biocleavable micelle compositions for use as drug carriers |
-
2001
- 2001-03-02 WO PCT/US2001/006829 patent/WO2001074401A2/en active Application Filing
- 2001-03-02 EP EP01914662A patent/EP1267936A2/en not_active Withdrawn
- 2001-03-02 AU AU2001240024A patent/AU2001240024A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0623354A1 (en) * | 1993-04-26 | 1994-11-09 | Medtronic, Inc. | Intravascular stents |
US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
WO1999030684A1 (en) * | 1997-12-12 | 1999-06-24 | Supergen, Inc. | Local delivery of therapeutic agents |
WO1999062510A2 (en) * | 1998-06-01 | 1999-12-09 | Angiotech Pharmaceuticals, Inc. | Compositions comprising anti-microtubule agents for treating or preventing inflammatory diseases |
WO2000000238A1 (en) * | 1998-06-26 | 2000-01-06 | Quanam Medical Corporation | Topoisomerase inhibitors for prevention of restenosis |
US20010021703A1 (en) * | 1998-12-30 | 2001-09-13 | Kosak Kenneth M. | Biocleavable micelle compositions for use as drug carriers |
Non-Patent Citations (7)
Title |
---|
FRIEDMAN HENRY S ET AL: "Treatment of central nervous system xenografts with camptothecins.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 803, 1996, Conference;Bethesda, Maryland, USA; February 7-10, 1996, discovery to the patient. 1996 New York Academy of Sciences 2 East 63rd Street, New York, New York 10021, USA, pages 210 - 212, XP001053589, ISBN: 1-57331-057-3 * |
GIOVANELLA B C ET AL: "Protocols for the treatment of human tumor xenografts with camptothecins.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 803, 1996, Conference;Bethesda, Maryland, USA; February 7-10, 1996, discovery to the patient. 1996 New York Academy of Sciences 2 East 63rd Street, New York, New York 10021, USA, pages 181 - 187, XP001053591, ISBN: 1-57331-057-3 * |
JONKMAN-DE VRIES J.D. ET AL: "Pharmaceutical development of (investigational) anticancer agents for parenteral use - A review", DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1996, VOL. 22, NO. 6, PAGE(S) 475-494, XP001053466 * |
NATELSON ETHAN A ET AL: "Phase I clinical and pharmacological studies of 20-(S)-camptothecin and 20-(S)-9-nitrocamptothecin as anticancer agents.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 803, 1996, Conference;Bethesda, Maryland, USA; February 7-10, 1996, discovery to the patient. 1996 New York Academy of Sciences 2 East 63rd Street, New York, New York 10021, USA, pages 224 - 230, XP001053588, ISBN: 1-57331-057-3 * |
SAIJO NAGAHIRO: "Clinical trials of irinotecan hydrochloride (CPT, campto injection, topotecan injection) in Japan.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 803, 1996, Conference;Bethesda, Maryland, USA; February 7-10, 1996, discovery to the patient. 1996 New York Academy of Sciences 2 East 63rd Street, New York, New York 10021, USA, pages 292 - 305, XP001053587, ISBN: 1-57331-057-3 * |
SHARMA U S ET AL: "PHARMACEUTICAL AND PHYSICAL PROPERTIES OF PACLITAXEL (TAXOL) COMPLEXES WITH CYCLODEXTRINS", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION. WASHINGTON, US, vol. 84, no. 10, 1 October 1995 (1995-10-01), pages 1223 - 1230, XP000529731, ISSN: 0022-3549 * |
UNDERBERG WJ ET AL: "Equilibrium kinetics of the new experimental anti-tumour compound SK&F 104864-A in aqueous solution.", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1990, VOL. 8, NO. 8-12, PAGE(S) 681-3, XP001053447 * |
Also Published As
Publication number | Publication date |
---|---|
EP1267936A2 (en) | 2003-01-02 |
AU2001240024A1 (en) | 2001-10-15 |
WO2001074401A2 (en) | 2001-10-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU8003800A (en) | Methods and compositions for treating neurobehavioral disorders | |
AU8016200A (en) | Process for producing, methods and compositions of cholesterol lowering agents from higher basidiomycetes mushrooms | |
WO2000006133A3 (en) | Compositions for treating diseases associated with glycosaminoglycan-associated molecular interactions | |
AU2719300A (en) | Antimicrobial compositions containing photosensitizers, articles, and methods ofuse | |
AU4659900A (en) | Treating compositions comprising polysaccharides | |
WO2001012199A3 (en) | Methoxyamine potentiation of temozolomide anti-cancer activity | |
CA2388646A1 (en) | Methods and compositions utilizing quinazolinones | |
EP2260835A3 (en) | Composition for proteasome inhibition | |
GB9903216D0 (en) | Preservative compounds,compositions and methods of making and using the same | |
WO2003094837A3 (en) | Treatments with autologous fibroblast | |
AU2003297318A1 (en) | Methods and compositions for treating cancer using 15986, 2188, 20743, 9148, 9151, 9791, 44252, 14184, 42461, 8204, 7970, 25552, 21657, 26492, 2411, 15088, 1905, 28899, 63380, 33935, 10480, 12686, 25501, 17694, 15701, 53062, 49908, 21612, 38949, 6216, 46863, 9235, 2201, 6985, 9883, 12238, 18057, 21617, 39228, 49928, 54476. | |
AU5601300A (en) | Method and compositions for treating and preventing retinal damage | |
WO2000066528A3 (en) | Quinones for treatment of diseases | |
HK1047707A1 (en) | Use of (+)-tramadol, o-demethyltramadol or (+)-o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol or (+)-o-desmethyl-n-mono-desmethyl-tramadol for treating urinary incontinence | |
AU7360000A (en) | Methods and compositions for preventing and treating prostate disorders | |
ZA200003768B (en) | Methods and compositions for treating diseases and conditions of the eye. | |
AU2002367023A1 (en) | Compositions and methods for treating heart failure | |
WO2001074401A3 (en) | Camptothecin complexes | |
MXPA02003232A (en) | Compositions and methods for altering gene expression. | |
AU4033900A (en) | Compositions and methods for treating cell proliferation disorders | |
AU2002365057A1 (en) | Compositions and methods for treating heart failure | |
WO2000053231A3 (en) | Fatty acid-anticancer conjugates and uses thereof | |
WO2002040001A3 (en) | Compositions for treatment of malignant effusions comprising a biocompatible polymer and antineoplastic taxane | |
WO2003007914A3 (en) | Biocompatible polymer containing composition for treatment of prostate cancers | |
AU3065299A (en) | Compositions and methods for treating atopic dermatitis, angioedema and other disorders using antihistamines and glucocorticoids |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2001914662 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 2001914662 Country of ref document: EP |
|
NENP | Non-entry into the national phase |
Ref country code: JP |