WO2001068664A3 - Mass labels - Google Patents

Mass labels Download PDF

Info

Publication number
WO2001068664A3
WO2001068664A3 PCT/GB2001/001122 GB0101122W WO0168664A3 WO 2001068664 A3 WO2001068664 A3 WO 2001068664A3 GB 0101122 W GB0101122 W GB 0101122W WO 0168664 A3 WO0168664 A3 WO 0168664A3
Authority
WO
WIPO (PCT)
Prior art keywords
mass
labels
label
group
different
Prior art date
Application number
PCT/GB2001/001122
Other languages
French (fr)
Other versions
WO2001068664A2 (en
Inventor
Gunter Schmidt
Andrew Hugin Thompson
Robert Alexander Wal Johnstone
Original Assignee
Xzillion Gmbh & Co Kg
Gunter Schmidt
Andrew Hugin Thompson
Robert Alexander Wal Johnstone
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9887608&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2001068664(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to AU4083401A priority Critical patent/AU4083401A/en
Priority to EP01911912A priority patent/EP1275004B1/en
Priority to CN018090419A priority patent/CN1427953B/en
Priority to US10/221,666 priority patent/US7294456B2/en
Priority to JP2001567754A priority patent/JP4608171B2/en
Priority to DK01911912T priority patent/DK1275004T3/en
Priority to AU2001240834A priority patent/AU2001240834B2/en
Priority to DE60128900T priority patent/DE60128900T2/en
Priority to IL15173201A priority patent/IL151732A0/en
Priority to CA002403114A priority patent/CA2403114C/en
Application filed by Xzillion Gmbh & Co Kg, Gunter Schmidt, Andrew Hugin Thompson, Robert Alexander Wal Johnstone filed Critical Xzillion Gmbh & Co Kg
Publication of WO2001068664A2 publication Critical patent/WO2001068664A2/en
Publication of WO2001068664A3 publication Critical patent/WO2001068664A3/en
Priority to IL151732A priority patent/IL151732A/en
Priority to NO20024344A priority patent/NO330733B1/en
Priority to US11/841,707 priority patent/US7816304B2/en
Priority to US11/894,735 priority patent/US7825069B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Abstract

Provided is a set of two or more mass labels, each label in the set comprising a mass marker moiety attached via a cleavable linker to a mass normalisation moiety, the mass marker moiety being fragmentation resistant, wherein the aggregate mass of each label in the set may be the same or different and the mass of the mass marker moiety of each label in the set may be the same or different, and wherein in any group of labels within the set having a mass marker moiety of a common mass each label has an aggregate mass different from all other labels in that group, and wherein in any group of labels within the set having a common aggregate mass each label has a mass marker moiety having a mass different from that of all other mass marker moieties in that group, such that all of the mass labels in the set are distinguishable from each other by mass spectrometry.
PCT/GB2001/001122 2000-03-14 2001-03-14 Mass labels WO2001068664A2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DE60128900T DE60128900T2 (en) 2000-03-14 2001-03-14 GROUND MARKER
CA002403114A CA2403114C (en) 2000-03-14 2001-03-14 Mass labels
IL15173201A IL151732A0 (en) 2000-03-14 2001-03-14 Mass labels
US10/221,666 US7294456B2 (en) 2000-03-14 2001-03-14 Mass labels
EP01911912A EP1275004B1 (en) 2000-03-14 2001-03-14 Mass labels
DK01911912T DK1275004T3 (en) 2000-03-14 2001-03-14 Mass labels
AU2001240834A AU2001240834B2 (en) 2000-03-14 2001-03-14 Mass labels
AU4083401A AU4083401A (en) 2000-03-14 2001-03-14 Mass labels
CN018090419A CN1427953B (en) 2000-03-14 2001-03-14 Mass labels
JP2001567754A JP4608171B2 (en) 2000-03-14 2001-03-14 Mass label
NO20024344A NO330733B1 (en) 2000-03-14 2002-09-12 Massemarkorer
IL151732A IL151732A (en) 2000-03-14 2002-09-12 Mass labels
US11/841,707 US7816304B2 (en) 2000-03-14 2007-08-20 Mass labels
US11/894,735 US7825069B2 (en) 2000-03-14 2007-08-20 Mass labels

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0006141.6 2000-03-14
GBGB0006141.6A GB0006141D0 (en) 2000-03-14 2000-03-14 Mass labels

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10221666 A-371-Of-International 2001-03-14
US11/841,707 Division US7816304B2 (en) 2000-03-14 2007-08-20 Mass labels
US11/894,735 Continuation US7825069B2 (en) 2000-03-14 2007-08-20 Mass labels

Publications (2)

Publication Number Publication Date
WO2001068664A2 WO2001068664A2 (en) 2001-09-20
WO2001068664A3 true WO2001068664A3 (en) 2002-03-21

Family

ID=9887608

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/001122 WO2001068664A2 (en) 2000-03-14 2001-03-14 Mass labels

Country Status (15)

Country Link
US (3) US7294456B2 (en)
EP (2) EP1806586B1 (en)
JP (1) JP4608171B2 (en)
CN (2) CN102839213A (en)
AT (1) ATE364841T1 (en)
AU (2) AU2001240834B2 (en)
CA (1) CA2403114C (en)
DE (1) DE60128900T2 (en)
DK (1) DK1275004T3 (en)
ES (2) ES2389510T3 (en)
GB (1) GB0006141D0 (en)
IL (2) IL151732A0 (en)
NO (1) NO330733B1 (en)
PT (1) PT1275004E (en)
WO (1) WO2001068664A2 (en)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999002728A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Characterising nucleic acids
AU8356201A (en) * 2000-08-11 2002-02-25 Agilix Corp Ultra-sensitive detection systems
ATE483161T1 (en) * 2001-04-03 2010-10-15 Thermo Finnigan Llc METHODS AND KITS SUITABLE FOR SIMPLIFYING COMPLEX PEPTIDE MIXTURES
DE60223696T2 (en) 2001-09-14 2009-01-29 Electrophoretics Ltd., Cobham GROUND MARKER
AU2002365271B2 (en) * 2001-11-06 2008-12-11 Agilix Corporation Sensitive coded detection systems
DE60231845D1 (en) * 2001-12-11 2009-05-14 Univ New Jersey Med DIAGNOSTIC PROCEDURE FOR PROTEIN PROFILING
AU2003224253A1 (en) 2002-04-04 2003-10-27 Electrophoretics Limited Method for characterising analytes
EP1588145B1 (en) 2003-01-30 2011-07-06 Life Technologies Corporation Methods, mixtures, kits and compositions pertaining to analyte determination
GB0306756D0 (en) * 2003-03-24 2003-04-30 Xzillion Gmbh & Co Kg Mass labels
US20060263886A1 (en) * 2003-11-14 2006-11-23 Eric Peters Fluorous labeling for selective processing of biologically-derived samples
US20050148087A1 (en) 2004-01-05 2005-07-07 Applera Corporation Isobarically labeled analytes and fragment ions derived therefrom
US20050148771A1 (en) 2004-01-05 2005-07-07 Applera Corporation. Active esters of N-substituted piperazine acetic acids, including isotopically enriched versions thereof
US7355045B2 (en) 2004-01-05 2008-04-08 Applera Corporation Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
WO2005085869A2 (en) * 2004-03-01 2005-09-15 Applera Corporation Determination of analyte characteristics based upon binding properties
WO2005101017A1 (en) * 2004-04-07 2005-10-27 Genentech, Inc. Mass spectrometry of antibody conjugates
CA2567459A1 (en) * 2004-05-19 2005-12-01 Applera Corporation Expression quantification using mass spectrometry
US20070054345A1 (en) * 2004-05-19 2007-03-08 Hunter Christie L Expression quantification using mass spectrometry
US20080206737A1 (en) * 2004-05-19 2008-08-28 Hunter Christie L Expression quantification using mass spectrometry
EP1756307A1 (en) 2004-05-20 2007-02-28 Trillion Genomics Limited Use of mass labelled probes to detect target nucleic acids using mass spectrometry
US20070048752A1 (en) * 2004-07-12 2007-03-01 Applera Corporation Mass tags for quantitative analyses
WO2006017208A1 (en) * 2004-07-12 2006-02-16 Applera Corporation Mass tags for quantitative analyses
CA2575675A1 (en) 2004-07-30 2006-03-09 Adeza Biomedical Corporation Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
JP2008529035A (en) * 2005-02-03 2008-07-31 パーキンエルマー エルエーエス，インク． Ultra-sensitive detection system using multidimensional signals
US20070037286A1 (en) * 2005-02-09 2007-02-15 Subhasish Purkayastha Thyroxine-containing compound analysis methods
US20060183238A1 (en) * 2005-02-09 2006-08-17 Applera Corporation Amine-containing compound analysis methods
GB0515323D0 (en) 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
JP4651094B2 (en) * 2005-08-09 2011-03-16 キヤノン株式会社 Labeled probe binding object, method for producing the same, and method for using the same
GB0518585D0 (en) 2005-09-12 2005-10-19 Electrophoretics Ltd Mass labels
WO2007078229A1 (en) * 2006-01-05 2007-07-12 Ge Healthcare Bio-Sciences Ab Kit and method for mass labelling
US7902345B2 (en) * 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US8133701B2 (en) * 2006-12-05 2012-03-13 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US7728287B2 (en) * 2007-03-01 2010-06-01 Lawrence Livermore National Security, Llc Imaging mass spectrometer with mass tags
GB0704764D0 (en) 2007-03-12 2007-04-18 Electrophoretics Ltd Isobarically labelled reagents and methods of their use
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
GB0809488D0 (en) 2008-05-23 2008-07-02 Electrophoretics Ltd Mass spectrometric analysis
GB0811574D0 (en) * 2008-06-24 2008-07-30 Trillion Genomics Ltd Characterising planar samples by mass spectrometry
EP2356259A4 (en) * 2008-10-30 2012-11-14 Sequenom Inc Products and processes for multiplex nucleic acid identification
EP2406634A4 (en) 2009-03-10 2013-06-19 Univ Maryland Deuterium isobaric tag reagents for quantitative analysis
GB0916881D0 (en) * 2009-09-25 2009-11-11 Electrophoretics Ltd Mass labels
GB0921665D0 (en) 2009-12-10 2010-01-27 Trillion Genomics Ltd Phobes
US8309359B2 (en) 2010-01-15 2012-11-13 California Institute Of Technology Isobaric tags for analyte detection and quantification
US8372653B2 (en) * 2010-01-22 2013-02-12 Dh Technologies Development Pte. Ltd. Mass tag reagents for simultaneous quantitation and identification of small molecules
ES2676183T3 (en) 2010-07-02 2018-07-17 Ventana Medical Systems, Inc. Target detection using mass marks and mass spectrometry
US8461987B2 (en) * 2010-11-17 2013-06-11 Theodosios Kountotsis System and method for performing chemical analysis of fingerprints for providing at least one response
WO2012159089A1 (en) * 2011-05-19 2012-11-22 Sequenom, Inc. Products and processes for multiplex nucleic acid identification
US9388132B2 (en) 2011-09-15 2016-07-12 Wisconsin Alumni Research Foundation Isobaric tandem mass tags for quantitative proteomics and peptidomics
WO2013170067A1 (en) 2012-05-10 2013-11-14 Thermo Finnigan Llc Method for highly multiplexed quantitation of peptides by mass spectrometry and labeling reagent sets therefor
US9366678B2 (en) 2012-10-25 2016-06-14 Wisconsin Alumni Research Foundation Neutron encoded mass tags for analyte quantification
CN105102977A (en) * 2012-12-26 2015-11-25 奎斯特诊断投资公司 C peptide detection by mass spectrometry
JP5569761B1 (en) * 2013-03-29 2014-08-13 シャープ株式会社 Analysis method
GB201308765D0 (en) * 2013-05-15 2013-06-26 Electrophoretics Ltd Mass Tag Reagents
GB201322567D0 (en) 2013-12-19 2014-02-05 Electrophoretics Ltd Mass labels
GB201410523D0 (en) 2014-06-12 2014-07-30 Electrophoretics Ltd Mass labels
AU2016250849A1 (en) 2015-04-24 2017-11-02 Agena Bioscience, Inc. Multiplex methods for detection and quantification of minor variants
US10233489B2 (en) 2015-04-24 2019-03-19 Agena Bioscience, Inc. Multiplexed method for the identification and quantitation of minor alleles and polymorphisms
GB201511508D0 (en) * 2015-07-01 2015-08-12 Ge Healthcare Bio Sciences Ab Method for determining a size of biomolecules
GB201521919D0 (en) 2015-12-11 2016-01-27 Electrophoretics Ltd Isobaric mass labels
GB201521903D0 (en) 2015-12-11 2016-01-27 Electrophoretics Ltd Isorbaric mass labels
CN108700551B (en) * 2016-02-22 2021-12-03 株式会社岛津制作所 Method for analyzing sialylated sugar chain
JP7051871B2 (en) * 2016-12-23 2022-04-11 エフ．ホフマン－ラ ロシュ アーゲー Methods for Identifying Reagents During Processes in Analytical Systems
JP7046070B2 (en) * 2016-12-23 2022-04-01 エフ．ホフマン－ラ ロシュ アーゲー Methods for Identifying Reagents During Processes in Analytical Systems
WO2018115243A1 (en) * 2016-12-23 2018-06-28 Roche Diagnostics Gmbh Method for tracking a sample identity during a process in an analysis system
JP2022526128A (en) * 2019-03-21 2022-05-23 シー２センス， インコーポレイテッド Systems and related methods for the detection of volatile ions
GB201907792D0 (en) 2019-05-31 2019-07-17 Thermo Fisher Scient Bremen Gmbh Deconvolution of mass spectromerty data
EP4047371A1 (en) 2021-02-18 2022-08-24 Thermo Fisher Scientific (Bremen) GmbH Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037041A2 (en) * 1996-03-18 1997-10-09 Sequenom, Inc. Dna sequencing by mass spectrometry
WO1998015652A1 (en) * 1996-10-04 1998-04-16 Brax Genomics Limited Nucleic acid sequencing by adaptator ligation
WO1998031830A1 (en) * 1997-01-15 1998-07-23 Brax Group Limited Mass label linked hybridisation probes
WO1999002728A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Characterising nucleic acids
WO1999013103A1 (en) * 1997-09-05 1999-03-18 Brax Group Limited Catalytically generated mass labels
WO1999014362A1 (en) * 1997-09-15 1999-03-25 Brax Group Limited Characterising nucleic acid by mass spectrometry

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5252296A (en) 1990-05-15 1993-10-12 Chiron Corporation Method and apparatus for biopolymer synthesis
GB9315847D0 (en) 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
JPH08145948A (en) * 1994-11-16 1996-06-07 Sumitomo Chem Co Ltd Mass spectrometry for reducible oligosaccharide
US6027890A (en) * 1996-01-23 2000-02-22 Rapigene, Inc. Methods and compositions for enhancing sensitivity in the analysis of biological-based assays
ES2144846T5 (en) 1996-01-23 2006-07-16 Qiagen Genomics, Inc. METHODS AND COMPOSITIONS TO DETERMINE THE SEQUENCE OF NUCLEIC ACID MOLECULES.
EP0863858B1 (en) 1996-04-08 2004-02-04 Glaxo Group Limited Mass-based encoding and qualitative analysis of combinatorial libraries
JPH10123096A (en) * 1996-10-22 1998-05-15 Sumitomo Chem Co Ltd Mass analysis method for sialooligosaccharide
DE69735445T2 (en) 1996-12-10 2006-08-10 Sequenom, Inc., San Diego NON-VOLATILE, NON-VOLATILE MOLECULES FOR MASS MARKING
FI106679B (en) * 1997-12-16 2001-03-15 Nokia Networks Oy Optical receiver
GB9815163D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds
GB9823646D0 (en) * 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry
AU8356201A (en) 2000-08-11 2002-02-25 Agilix Corp Ultra-sensitive detection systems
US9722639B2 (en) 2013-05-01 2017-08-01 Qorvo Us, Inc. Carrier aggregation arrangements for mobile devices
US9701046B2 (en) 2013-06-21 2017-07-11 Pavestone, LLC Method and apparatus for dry cast facing concrete deposition
US9187086B1 (en) 2014-05-22 2015-11-17 Ford Global Technologies, Llc Clutch control to enter powersplit hybrid powertrain parallel mode
US9701070B2 (en) 2014-11-06 2017-07-11 Lockheed Martin Corporation Mandrel forming for discrete wing skin stiffeners

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997037041A2 (en) * 1996-03-18 1997-10-09 Sequenom, Inc. Dna sequencing by mass spectrometry
WO1998015652A1 (en) * 1996-10-04 1998-04-16 Brax Genomics Limited Nucleic acid sequencing by adaptator ligation
WO1998031830A1 (en) * 1997-01-15 1998-07-23 Brax Group Limited Mass label linked hybridisation probes
WO1999002728A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Characterising nucleic acids
WO1999013103A1 (en) * 1997-09-05 1999-03-18 Brax Group Limited Catalytically generated mass labels
WO1999014362A1 (en) * 1997-09-15 1999-03-25 Brax Group Limited Characterising nucleic acid by mass spectrometry

Also Published As

Publication number Publication date
US7294456B2 (en) 2007-11-13
CA2403114C (en) 2007-07-31
CN1427953A (en) 2003-07-02
US20080167197A1 (en) 2008-07-10
CA2403114A1 (en) 2001-09-20
IL151732A0 (en) 2003-04-10
PT1275004E (en) 2007-08-14
AU2001240834B2 (en) 2005-11-17
IL151732A (en) 2008-11-03
US20080145850A1 (en) 2008-06-19
NO20024344D0 (en) 2002-09-12
DE60128900T2 (en) 2008-02-07
DK1275004T3 (en) 2007-10-15
ES2287104T3 (en) 2007-12-16
JP4608171B2 (en) 2011-01-05
NO330733B1 (en) 2011-06-27
US20030194717A1 (en) 2003-10-16
JP2003529059A (en) 2003-09-30
WO2001068664A2 (en) 2001-09-20
AU4083401A (en) 2001-09-24
US7816304B2 (en) 2010-10-19
ES2389510T3 (en) 2012-10-26
CN1427953B (en) 2012-08-29
DE60128900D1 (en) 2007-07-26
ATE364841T1 (en) 2007-07-15
US7825069B2 (en) 2010-11-02
NO20024344L (en) 2002-11-14
EP1275004B1 (en) 2007-06-13
EP1275004A2 (en) 2003-01-15
EP1806586A1 (en) 2007-07-11
CN102839213A (en) 2012-12-26
EP1806586B1 (en) 2012-08-15
GB0006141D0 (en) 2000-05-03

Similar Documents

Publication Publication Date Title
WO2001068664A3 (en) Mass labels
CA2460131A1 (en) Mass labels
GB0518585D0 (en) Mass labels
WO2003048387A3 (en) Labelled nucleotides
AU2002257403A1 (en) Biopolymer marker having a molecular weight of 1350 daltons
AU2001251217A1 (en) Compostable, degradable plastic compositions and articles thereof
WO2001068146A3 (en) Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene
MXPA01012610A (en) Adhesive binder and synergist composition and process of making lignocellulosic articles.
AU2002216774A1 (en) Eas marker
AU2001288360A1 (en) Genomics-assisted rapid identification of targets
AU2002252905A1 (en) Biopolymer marker having a molecular weight of 2937 daltons
AU2002257404A1 (en) Biopolymer marker having a molecular weight of 1449 daltons
AU7622600A (en) Ascot collar bar
AU2002254829A1 (en) Biopolymer marker having a molecular weight of 1097 daltons
AU2002252893A1 (en) Biopolymer marker having a molecular weight of 1465 daltons
AU2002308308A1 (en) Biopolymer marker having a molecular weight of 1424 daltons
AU2002308320A1 (en) Biopolymer marker having a molecular weight of 1845 daltons
AU2001250793A1 (en) Flame retardant, high impact monovinylidene aromatic polymer composition
AU2002252910A1 (en) Biopolymer marker having a molecular weight of 2267 daltons
AU2002257402A1 (en) Biopolymer marker having a molecular weight of 1206 daltons
AU2002252904A1 (en) Biopolymer marker having a molecular weight of 1896 daltons
AU2002252907A1 (en) Biopolymer marker having a molecular weight of 1690 daltons
WO2002014381A3 (en) Non-pressurized methods for the preparation of conjugated solid supports for boronic acids
AU2002308316A1 (en) Biopolymer marker state having a molecular weight of 1777 daltons
AU2001241622A1 (en) Novel defense induced genes and uses thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 151732

Country of ref document: IL

Ref document number: 2001911912

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2403114

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2001 567754

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2001240834

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 521527

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 018090419

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2001911912

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 10221666

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 521527

Country of ref document: NZ

WWG Wipo information: grant in national office

Ref document number: 521527

Country of ref document: NZ

WWG Wipo information: grant in national office

Ref document number: 2001240834

Country of ref document: AU

WWG Wipo information: grant in national office

Ref document number: 2001911912

Country of ref document: EP