WO2001064344A3 - Microfabricated devices for the storage and selective exposure of chemicals and devices - Google Patents

Microfabricated devices for the storage and selective exposure of chemicals and devices Download PDF

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Publication number
WO2001064344A3
WO2001064344A3 PCT/US2001/006886 US0106886W WO0164344A3 WO 2001064344 A3 WO2001064344 A3 WO 2001064344A3 US 0106886 W US0106886 W US 0106886W WO 0164344 A3 WO0164344 A3 WO 0164344A3
Authority
WO
WIPO (PCT)
Prior art keywords
devices
reservoirs
chemicals
storage
selective exposure
Prior art date
Application number
PCT/US2001/006886
Other languages
French (fr)
Other versions
WO2001064344A2 (en
Inventor
John T Santini Jr
Norman F Sheppard Jr
Chung Chang Young
Robert S Langer
Original Assignee
Microchips Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microchips Inc filed Critical Microchips Inc
Priority to DE60144142T priority Critical patent/DE60144142D1/en
Priority to AT01926347T priority patent/ATE499988T1/en
Priority to ES01926347T priority patent/ES2420279T3/en
Priority to AU5289001A priority patent/AU5289001A/en
Priority to EP01926347A priority patent/EP1261427B1/en
Priority to CA002399842A priority patent/CA2399842C/en
Priority to AU2001252890A priority patent/AU2001252890B2/en
Priority to JP2001563234A priority patent/JP3960802B2/en
Publication of WO2001064344A2 publication Critical patent/WO2001064344A2/en
Publication of WO2001064344A3 publication Critical patent/WO2001064344A3/en
Priority to AU2005204238A priority patent/AU2005204238B2/en

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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G01N2035/00247—Microvalves
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49002—Electrical device making
    • Y10T29/49007—Indicating transducer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49002—Electrical device making
    • Y10T29/49117—Conductor or circuit manufacturing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation

Abstract

Microchip devices are provided which include a substrate having a plurality of reservoirs containing a secondary device, a reacting component, or a combination thereof. At least one barrier layer covers each reservoir to isolate the reservoir contents from one or more environmental components outside the reservoirs. The barrier layer can be selectively disintegrated or permeabilized to expose the isolated contents to the one or more environmental components. The secondary device preferably includes a sensor or sensing component, for example, a biosensor, or a light detection or imaging device, such as an optical fiber. Preferred reacting components include catalyst and reagent, which may be immobilized in the reservoirs.
PCT/US2001/006886 2000-03-02 2001-03-02 Microfabricated devices for the storage and selective exposure of chemicals and devices WO2001064344A2 (en)

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DE60144142T DE60144142D1 (en) 2000-03-02 2001-03-02 MICROMECHANICAL DEVICES AND METHOD FOR THE STORAGE AND SELECTIVE EXPOSURE OF CHEMICALS
AT01926347T ATE499988T1 (en) 2000-03-02 2001-03-02 MICROMECHANICAL DEVICES AND METHODS FOR STORAGE AND SELECTIVE EXPOSURE OF CHEMICALS
ES01926347T ES2420279T3 (en) 2000-03-02 2001-03-02 Microfabricated devices and methods for storage and selective exposure of chemicals
AU5289001A AU5289001A (en) 2000-03-02 2001-03-02 Microfabricated devices for the storage and selective exposure of chemicals and devices
EP01926347A EP1261427B1 (en) 2000-03-02 2001-03-02 Microfabricated devices and methods for storage and selective exposure of chemicals
CA002399842A CA2399842C (en) 2000-03-02 2001-03-02 Microfabricated devices for the storage and selective exposure of chemicals and devices
AU2001252890A AU2001252890B2 (en) 2000-03-02 2001-03-02 Microfabricated devices for the storage and selective exposure of chemicals and devices
JP2001563234A JP3960802B2 (en) 2000-03-02 2001-03-02 Microfabricated devices for storing and selectively exposing chemicals and devices
AU2005204238A AU2005204238B2 (en) 2000-03-02 2005-08-25 Microfabricated devices for the storage and selective exposure of chemicals and devices

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US18654500P 2000-03-02 2000-03-02
US60/186,545 2000-03-02

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