WO2001060424A3 - Implantable tissues infused with growth factors and other additives - Google Patents
Implantable tissues infused with growth factors and other additives Download PDFInfo
- Publication number
- WO2001060424A3 WO2001060424A3 PCT/US2001/005414 US0105414W WO0160424A3 WO 2001060424 A3 WO2001060424 A3 WO 2001060424A3 US 0105414 W US0105414 W US 0105414W WO 0160424 A3 WO0160424 A3 WO 0160424A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- additives
- growth factors
- tissue
- implantable tissues
- infused
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002399224A CA2399224A1 (en) | 2000-02-18 | 2001-02-20 | Implantable tissues infused with growth factors and other additives |
JP2001559519A JP2003535620A (en) | 2000-02-18 | 2001-02-20 | Transplant tissue implanted with growth factors and other additives |
AU2001241594A AU2001241594A1 (en) | 2000-02-18 | 2001-02-20 | Implantable tissues infused with growth factors and other additives |
EP01912854A EP1286707A2 (en) | 2000-02-18 | 2001-02-20 | Implantable tissues infused with growth factors and other additives |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18346800P | 2000-02-18 | 2000-02-18 | |
US60/183,468 | 2000-02-18 | ||
US18420300P | 2000-02-22 | 2000-02-22 | |
US60/184,203 | 2000-02-22 | ||
US19747700P | 2000-04-17 | 2000-04-17 | |
US60/197,477 | 2000-04-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001060424A2 WO2001060424A2 (en) | 2001-08-23 |
WO2001060424A3 true WO2001060424A3 (en) | 2002-12-27 |
Family
ID=27391680
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/005414 WO2001060424A2 (en) | 2000-02-18 | 2001-02-20 | Implantable tissues infused with growth factors and other additives |
Country Status (6)
Country | Link |
---|---|
US (1) | US20010038848A1 (en) |
EP (1) | EP1286707A2 (en) |
JP (1) | JP2003535620A (en) |
AU (1) | AU2001241594A1 (en) |
CA (1) | CA2399224A1 (en) |
WO (1) | WO2001060424A2 (en) |
Cited By (7)
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US8870954B2 (en) | 2008-09-09 | 2014-10-28 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
US8877175B2 (en) | 2006-09-14 | 2014-11-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9155749B2 (en) | 2006-09-14 | 2015-10-13 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
US9545377B2 (en) | 2004-10-14 | 2017-01-17 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor compositions and methods of use thereof |
CN110612129B (en) * | 2017-10-19 | 2022-02-22 | 执行生物制药有限公司 | Autologous bone graft substitute |
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US6179840B1 (en) | 1999-07-23 | 2001-01-30 | Ethicon, Inc. | Graft fixation device and method |
US20020095157A1 (en) | 1999-07-23 | 2002-07-18 | Bowman Steven M. | Graft fixation device combination |
CA2365376C (en) | 2000-12-21 | 2006-03-28 | Ethicon, Inc. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
US8088568B2 (en) | 2001-11-05 | 2012-01-03 | Medgentics, Inc. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US7468242B2 (en) | 2001-11-05 | 2008-12-23 | Medgenics, Inc. | Dermal micro organs, methods and apparatuses for producing and using the same |
US8501396B2 (en) | 2001-11-05 | 2013-08-06 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US7205337B2 (en) * | 2001-12-21 | 2007-04-17 | Isotis Orthobiologics, Inc. | End-capped polymers and compositions containing such compounds |
US7923431B2 (en) | 2001-12-21 | 2011-04-12 | Ferrosan Medical Devices A/S | Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis |
CA2471403A1 (en) * | 2001-12-21 | 2003-07-10 | Gensci Orthobiologics, Inc. | End-capped polyalkylene glycols and compositions containing such compounds |
US20060204544A1 (en) * | 2002-05-20 | 2006-09-14 | Musculoskeletal Transplant Foundation | Allograft bone composition having a gelatin binder |
ES2524444T3 (en) * | 2002-06-27 | 2014-12-09 | Roberto Beretta | Method for preparing a solid fibrin sheet |
JP2004123576A (en) * | 2002-09-30 | 2004-04-22 | Medgel Corp | Sustained release preparation containing platelet-rich plasma |
US20040078090A1 (en) | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
US7824701B2 (en) | 2002-10-18 | 2010-11-02 | Ethicon, Inc. | Biocompatible scaffold for ligament or tendon repair |
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US7087086B2 (en) * | 2003-01-31 | 2006-08-08 | Depuy Products, Inc. | Biological agent-containing ceramic coating and method |
US8197837B2 (en) | 2003-03-07 | 2012-06-12 | Depuy Mitek, Inc. | Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof |
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US6905723B2 (en) * | 2003-05-30 | 2005-06-14 | Depuy Products, Inc. | Strontium-substituted apatite coating |
US8226715B2 (en) | 2003-06-30 | 2012-07-24 | Depuy Mitek, Inc. | Scaffold for connective tissue repair |
US10583220B2 (en) | 2003-08-11 | 2020-03-10 | DePuy Synthes Products, Inc. | Method and apparatus for resurfacing an articular surface |
US7375077B2 (en) * | 2003-09-19 | 2008-05-20 | The Board Of Trustees Of The University Of Illinois | In vivo synthesis of connective tissues |
US7316822B2 (en) | 2003-11-26 | 2008-01-08 | Ethicon, Inc. | Conformable tissue repair implant capable of injection delivery |
US20050125033A1 (en) * | 2003-12-04 | 2005-06-09 | Mcnally-Heintzelman Karen M. | Wound closure apparatus |
US20050125015A1 (en) * | 2003-12-04 | 2005-06-09 | Mcnally-Heintzelman Karen M. | Tissue-handling apparatus, system and method |
US7901461B2 (en) * | 2003-12-05 | 2011-03-08 | Ethicon, Inc. | Viable tissue repair implants and methods of use |
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US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
US20050196519A1 (en) * | 2004-03-08 | 2005-09-08 | Depuy Products, Inc. | Apparatus for producing a biomimetic coating on a medical implant |
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US20060085003A1 (en) * | 2004-10-05 | 2006-04-20 | Arthrex, Inc. | Use of autogenous growth factors in bone tunnels during ligament reconstruction |
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CH211207A (en) * | 1940-01-23 | 1940-08-31 | Kuhn Kramer Karoline | Process for the production of a hemostatic and wound healing agent. |
US5298254A (en) * | 1989-09-21 | 1994-03-29 | Osteotech, Inc. | Shaped, swollen demineralized bone and its use in bone repair |
US5322499A (en) * | 1985-09-20 | 1994-06-21 | Liprie Sam F | Continuous sheated low dose radioactive core adapted for cutting into short sealed segments |
US5556430A (en) * | 1990-10-31 | 1996-09-17 | Gendler; El | Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction |
WO1999048540A1 (en) * | 1998-03-23 | 1999-09-30 | Bio-Vascular, Inc. | Implants and method of making |
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-
2001
- 2001-02-20 US US09/789,292 patent/US20010038848A1/en not_active Abandoned
- 2001-02-20 AU AU2001241594A patent/AU2001241594A1/en not_active Abandoned
- 2001-02-20 CA CA002399224A patent/CA2399224A1/en not_active Abandoned
- 2001-02-20 WO PCT/US2001/005414 patent/WO2001060424A2/en not_active Application Discontinuation
- 2001-02-20 JP JP2001559519A patent/JP2003535620A/en active Pending
- 2001-02-20 EP EP01912854A patent/EP1286707A2/en not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH211207A (en) * | 1940-01-23 | 1940-08-31 | Kuhn Kramer Karoline | Process for the production of a hemostatic and wound healing agent. |
US5322499A (en) * | 1985-09-20 | 1994-06-21 | Liprie Sam F | Continuous sheated low dose radioactive core adapted for cutting into short sealed segments |
US5298254A (en) * | 1989-09-21 | 1994-03-29 | Osteotech, Inc. | Shaped, swollen demineralized bone and its use in bone repair |
US5556430A (en) * | 1990-10-31 | 1996-09-17 | Gendler; El | Flexible membranes produced from organic bone matrix for skeletal repair and reconstruction |
WO1999048540A1 (en) * | 1998-03-23 | 1999-09-30 | Bio-Vascular, Inc. | Implants and method of making |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9545377B2 (en) | 2004-10-14 | 2017-01-17 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor compositions and methods of use thereof |
US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
US8877175B2 (en) | 2006-09-14 | 2014-11-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9155749B2 (en) | 2006-09-14 | 2015-10-13 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US8870954B2 (en) | 2008-09-09 | 2014-10-28 | Biomimetic Therapeutics, Llc | Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries |
CN110612129B (en) * | 2017-10-19 | 2022-02-22 | 执行生物制药有限公司 | Autologous bone graft substitute |
Also Published As
Publication number | Publication date |
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JP2003535620A (en) | 2003-12-02 |
EP1286707A2 (en) | 2003-03-05 |
CA2399224A1 (en) | 2001-08-23 |
WO2001060424A2 (en) | 2001-08-23 |
US20010038848A1 (en) | 2001-11-08 |
AU2001241594A1 (en) | 2001-08-27 |
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