WO2001049364A3 - A communications system for an implantable device and a drug dispenser - Google Patents

A communications system for an implantable device and a drug dispenser Download PDF

Info

Publication number
WO2001049364A3
WO2001049364A3 PCT/US2000/031890 US0031890W WO0149364A3 WO 2001049364 A3 WO2001049364 A3 WO 2001049364A3 US 0031890 W US0031890 W US 0031890W WO 0149364 A3 WO0149364 A3 WO 0149364A3
Authority
WO
WIPO (PCT)
Prior art keywords
patient
drug
imds
monitor
data center
Prior art date
Application number
PCT/US2000/031890
Other languages
French (fr)
Other versions
WO2001049364A2 (en
Inventor
Dwight H Warkentin
Bozidar Ferek-Petric
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to EP00980586A priority Critical patent/EP1246663B1/en
Priority to DE60017943T priority patent/DE60017943T2/en
Publication of WO2001049364A2 publication Critical patent/WO2001049364A2/en
Publication of WO2001049364A3 publication Critical patent/WO2001049364A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
    • A61N1/37282—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data characterised by communication with experts in remote locations using a network
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/903—Radio telemetry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/904—Telephone telemetry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00—Surgery
    • Y10S128/92—Computer assisted medical diagnostics

Abstract

A closed loop system for monitoring drug dose, intake and effectiveness includes a pill dispenser in data communications with at least one implantable medical device. The system is preferably implemented in a web-enabled environment in which a remote data center communicates with the implantable devices (IMDs) in a patient via a programmer or the pill dispenser. The data center includes high speed computers and databases relating to patient history and device information. A physician or clinician may access the remote data center to review and monitor the IMDs remotely. More specifically, the IMDs are adapted to chronically monitor the pill dispenser to thereby log and document drug dose, patient compliance with prescriptive regimens and as well to monitor drug efficacy in the patient. The system further provides a dynamic drug management system, compatible with a web-enabled interactive data communication environment, that accurately monitors dose and specific drug effectiveness in a patient to enhance patient care.
PCT/US2000/031890 1999-12-30 2000-11-20 A communications system for an implantable device and a drug dispenser WO2001049364A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00980586A EP1246663B1 (en) 1999-12-30 2000-11-20 A communications system for an implantable device and a drug dispenser
DE60017943T DE60017943T2 (en) 1999-12-30 2000-11-20 COMMUNICATION SYSTEM FOR AN IMPLANTABLE DEVICE AND A MEDICAL DISPENSER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/475,709 US6471645B1 (en) 1999-12-30 1999-12-30 Communications system for an implantable device and a drug dispenser
US09/475,709 1999-12-30

Publications (2)

Publication Number Publication Date
WO2001049364A2 WO2001049364A2 (en) 2001-07-12
WO2001049364A3 true WO2001049364A3 (en) 2002-05-23

Family

ID=23888775

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031890 WO2001049364A2 (en) 1999-12-30 2000-11-20 A communications system for an implantable device and a drug dispenser

Country Status (4)

Country Link
US (2) US6471645B1 (en)
EP (1) EP1246663B1 (en)
DE (1) DE60017943T2 (en)
WO (1) WO2001049364A2 (en)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8847766B2 (en) 2005-04-28 2014-09-30 Proteus Digital Health, Inc. Pharma-informatics system
US8855775B2 (en) 2006-11-14 2014-10-07 Cyberonics, Inc. Systems and methods of reducing artifact in neurological stimulation systems
US8858432B2 (en) 2007-02-01 2014-10-14 Proteus Digital Health, Inc. Ingestible event marker systems
US8868453B2 (en) 2009-11-04 2014-10-21 Proteus Digital Health, Inc. System for supply chain management
US8932221B2 (en) 2007-03-09 2015-01-13 Proteus Digital Health, Inc. In-body device having a multi-directional transmitter
US8945005B2 (en) 2006-10-25 2015-02-03 Proteus Digital Health, Inc. Controlled activation ingestible identifier
US8956287B2 (en) 2006-05-02 2015-02-17 Proteus Digital Health, Inc. Patient customized therapeutic regimens
US8956288B2 (en) 2007-02-14 2015-02-17 Proteus Digital Health, Inc. In-body power source having high surface area electrode
US8961412B2 (en) 2007-09-25 2015-02-24 Proteus Digital Health, Inc. In-body device with virtual dipole signal amplification
US9060708B2 (en) 2008-03-05 2015-06-23 Proteus Digital Health, Inc. Multi-mode communication ingestible event markers and systems, and methods of using the same
US9083589B2 (en) 2006-11-20 2015-07-14 Proteus Digital Health, Inc. Active signal processing personal health signal receivers
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
US9289595B2 (en) 2009-01-09 2016-03-22 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US9445730B2 (en) 2007-03-21 2016-09-20 Cyberonics, Inc. Implantable systems and methods for identifying a contra-ictal condition in a subject

Families Citing this family (306)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030036746A1 (en) 2001-08-16 2003-02-20 Avi Penner Devices for intrabody delivery of molecules and systems and methods utilizing same
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US9375573B2 (en) 1998-08-05 2016-06-28 Cyberonics, Inc. Systems and methods for monitoring a patient's neurological disease state
US7853329B2 (en) 1998-08-05 2010-12-14 Neurovista Corporation Monitoring efficacy of neural modulation therapy
US7209787B2 (en) 1998-08-05 2007-04-24 Bioneuronics Corporation Apparatus and method for closed-loop intracranial stimulation for optimal control of neurological disease
US7747325B2 (en) 1998-08-05 2010-06-29 Neurovista Corporation Systems and methods for monitoring a patient's neurological disease state
US9042988B2 (en) 1998-08-05 2015-05-26 Cyberonics, Inc. Closed-loop vagus nerve stimulation
US9415222B2 (en) 1998-08-05 2016-08-16 Cyberonics, Inc. Monitoring an epilepsy disease state with a supervisory module
US8762065B2 (en) 1998-08-05 2014-06-24 Cyberonics, Inc. Closed-loop feedback-driven neuromodulation
US6564104B2 (en) * 1999-12-24 2003-05-13 Medtronic, Inc. Dynamic bandwidth monitor and adjuster for remote communications with a medical device
US8002700B2 (en) * 1999-12-30 2011-08-23 Medtronic, Inc. Communications system for an implantable medical device and a delivery device
US6622050B2 (en) 2000-03-31 2003-09-16 Medtronic, Inc. Variable encryption scheme for data transfer between medical devices and related data management systems
US6735479B2 (en) * 2000-06-14 2004-05-11 Medtronic, Inc. Lifestyle management system
US20020087113A1 (en) * 2000-12-29 2002-07-04 Medtronic, Inc. Drug management techniques for an implantable medical device
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6749566B2 (en) * 2001-02-14 2004-06-15 Draeger Medical Systems, Inc. Patient monitoring area network
US6949929B2 (en) * 2003-06-24 2005-09-27 Biophan Technologies, Inc. Magnetic resonance imaging interference immune device
US20050283167A1 (en) * 2003-08-25 2005-12-22 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20050283214A1 (en) * 2003-08-25 2005-12-22 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20050288753A1 (en) * 2003-08-25 2005-12-29 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20070168006A1 (en) * 2001-02-20 2007-07-19 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20070168005A1 (en) * 2001-02-20 2007-07-19 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20070173911A1 (en) * 2001-02-20 2007-07-26 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
US20050119580A1 (en) 2001-04-23 2005-06-02 Eveland Doug C. Controlling access to a medical monitoring system
JP4498636B2 (en) 2001-04-27 2010-07-07 日本サーモスタット株式会社 Thermostat device
US6941168B2 (en) * 2001-12-12 2005-09-06 Cardiac Pacemakers, Inc. System and method for treating an adverse cardiac condition using combined pacing and drug delivery
US8775196B2 (en) 2002-01-29 2014-07-08 Baxter International Inc. System and method for notification and escalation of medical data
US10173008B2 (en) 2002-01-29 2019-01-08 Baxter International Inc. System and method for communicating with a dialysis machine through a network
US20030149593A1 (en) * 2002-02-04 2003-08-07 Msc Healthcare (S) Pte. Ltd. Health-care system
US6985773B2 (en) 2002-02-07 2006-01-10 Cardiac Pacemakers, Inc. Methods and apparatuses for implantable medical device telemetry power management
US8234128B2 (en) 2002-04-30 2012-07-31 Baxter International, Inc. System and method for verifying medical device operational parameters
US20040172290A1 (en) * 2002-07-15 2004-09-02 Samuel Leven Health monitoring device
US7086532B2 (en) * 2003-07-16 2006-08-08 Allergan, Inc. Titration/compliance pack with increasing doses
US7328069B2 (en) * 2002-09-06 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves
US7427280B2 (en) 2002-09-06 2008-09-23 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by delivering drugs to various nerves or tissues
US7276057B2 (en) * 2002-09-06 2007-10-02 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by drug delivery to the pudendal and sacral nerves
US7369894B2 (en) * 2002-09-06 2008-05-06 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of the sacral and/or pudendal nerves
US7328068B2 (en) * 2003-03-31 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by means of electrical stimulation of the pudendal and associated nerves, and the optional delivery of drugs in association therewith
US7065409B2 (en) * 2002-12-13 2006-06-20 Cardiac Pacemakers, Inc. Device communications of an implantable medical device and an external system
US7009511B2 (en) 2002-12-17 2006-03-07 Cardiac Pacemakers, Inc. Repeater device for communications with an implantable medical device
US7127300B2 (en) 2002-12-23 2006-10-24 Cardiac Pacemakers, Inc. Method and apparatus for enabling data communication between an implantable medical device and a patient management system
US7395117B2 (en) * 2002-12-23 2008-07-01 Cardiac Pacemakers, Inc. Implantable medical device having long-term wireless capabilities
US20040128161A1 (en) * 2002-12-27 2004-07-01 Mazar Scott T. System and method for ad hoc communications with an implantable medical device
NZ523948A (en) * 2003-01-30 2006-08-31 Sensortec Ltd Animal control system
EP2374406B1 (en) * 2003-01-30 2013-06-05 Accenture Global Services Limited Event data acquisition and transmission system
US7742821B1 (en) * 2003-06-11 2010-06-22 Boston Scientific Neutomodulation Corporation Remote control for implantable medical device
US20040210273A1 (en) * 2003-04-18 2004-10-21 Medtronic, Inc. Presentation of patient image with implantable medical device information
US20040225199A1 (en) * 2003-05-08 2004-11-11 Evanyk Shane Walter Advanced physiological monitoring systems and methods
US7769465B2 (en) * 2003-06-11 2010-08-03 Matos Jeffrey A System for cardiac resuscitation
US9082156B2 (en) * 2005-08-17 2015-07-14 Jeffrey A. Matos Emergency management system
CA2533014A1 (en) * 2003-06-23 2004-12-29 Seiko Instruments Inc. Health care system, biological information terminal
US7289761B2 (en) * 2003-06-23 2007-10-30 Cardiac Pacemakers, Inc. Systems, devices, and methods for selectively preventing data transfer from a medical device
US7388378B2 (en) * 2003-06-24 2008-06-17 Medtronic, Inc. Magnetic resonance imaging interference immune device
US7839146B2 (en) * 2003-06-24 2010-11-23 Medtronic, Inc. Magnetic resonance imaging interference immune device
DE10333133A1 (en) * 2003-07-21 2005-03-03 Siemens Ag Implant according to the "thin client" principle
US20050050042A1 (en) * 2003-08-20 2005-03-03 Marvin Elder Natural language database querying
US20050288752A1 (en) * 2003-08-25 2005-12-29 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20050283213A1 (en) * 2003-08-25 2005-12-22 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20050288755A1 (en) * 2003-08-25 2005-12-29 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US8868212B2 (en) * 2003-08-25 2014-10-21 Medtronic, Inc. Medical device with an electrically conductive anti-antenna member
US20050049481A1 (en) * 2003-08-25 2005-03-03 Biophan Technologies, Inc. Electromagnetic radiation transparent device and method of making thereof
US20050288754A1 (en) * 2003-08-25 2005-12-29 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20050288756A1 (en) * 2003-08-25 2005-12-29 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US20050288751A1 (en) * 2003-08-25 2005-12-29 Biophan Technologies, Inc. Medical device with an electrically conductive anti-antenna member
US7315760B2 (en) * 2003-10-15 2008-01-01 Ge Medical Systems Information Technologies, Inc. Detection of function of implanted medical devices
US7226430B2 (en) * 2003-12-26 2007-06-05 Codman & Shurtleff, Inc. Closed loop system and method for controlling muscle activity via an intrathecal catheter
US8165695B2 (en) * 2004-02-11 2012-04-24 Ethicon, Inc. System and method for selectively stimulating different body parts
US8751003B2 (en) 2004-02-11 2014-06-10 Ethicon, Inc. Conductive mesh for neurostimulation
US20050177067A1 (en) * 2004-02-11 2005-08-11 Tracey Michael R. System and method for urodynamic evaluation utilizing micro-electronic mechanical system
US7647112B2 (en) * 2004-02-11 2010-01-12 Ethicon, Inc. System and method for selectively stimulating different body parts
US7979137B2 (en) 2004-02-11 2011-07-12 Ethicon, Inc. System and method for nerve stimulation
US8467875B2 (en) 2004-02-12 2013-06-18 Medtronic, Inc. Stimulation of dorsal genital nerves to treat urologic dysfunctions
US20050187789A1 (en) * 2004-02-25 2005-08-25 Cardiac Pacemakers, Inc. Advanced patient and medication therapy management system and method
WO2005099817A1 (en) 2004-04-07 2005-10-27 Cardiac Pacemakers, Inc. Rf wake-up of implantable medical device
US20050261559A1 (en) * 2004-05-18 2005-11-24 Mumford John R Wireless physiological monitoring system
US8961461B2 (en) 2004-05-27 2015-02-24 Baxter International Inc. Multi-state alarm system for a medical pump
US7927313B2 (en) 2004-05-27 2011-04-19 Baxter International Inc. Medical device configuration based on recognition of identification information
US7794499B2 (en) 2004-06-08 2010-09-14 Theken Disc, L.L.C. Prosthetic intervertebral spinal disc with integral microprocessor
US7565197B2 (en) * 2004-06-18 2009-07-21 Medtronic, Inc. Conditional requirements for remote medical device programming
US7697994B2 (en) * 2004-06-18 2010-04-13 Medtronic, Inc. Remote scheduling for management of an implantable medical device
WO2006023700A2 (en) * 2004-08-20 2006-03-02 Biophan Technologies, Inc. Magnetic resonance imaging interference immune device
US20060064133A1 (en) 2004-09-17 2006-03-23 Cardiac Pacemakers, Inc. System and method for deriving relative physiologic measurements using an external computing device
US8150509B2 (en) 2004-10-21 2012-04-03 Cardiac Pacemakers, Inc. Systems and methods for drug therapy enhancement using expected pharmacodynamic models
US7813808B1 (en) 2004-11-24 2010-10-12 Remon Medical Technologies Ltd Implanted sensor system with optimized operational and sensing parameters
US7218969B2 (en) * 2005-01-19 2007-05-15 Cardiac Pacemakers, Inc. Dynamic channel selection for RF telemetry with implantable device
US20060206066A1 (en) * 2005-03-10 2006-09-14 Bozidar Ferek-Petric Communications system for an implantable device and a drug dispenser
US7526335B2 (en) * 2005-03-10 2009-04-28 Medtronic, Inc. Communications system for an implantable device and a drug dispenser
DE102005015010A1 (en) * 2005-04-01 2006-10-05 Christoph Eder Medicament e.g. birth control pill, dispenser for use in mobile telephone, has repository filled with pill stock, where message in the form of tone, vibration or light signal is repeated when release of pills is delayed
US8438039B2 (en) 2005-04-27 2013-05-07 Medtronic, Inc. User customizable workflow preferences for remote patient management
US7664553B2 (en) 2005-04-27 2010-02-16 Cardiac Pacemakers, Inc. System and method for enabling communications with implantable medical devices
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
US8915893B2 (en) 2005-05-10 2014-12-23 Palyon Medical (Bvi) Limited Variable flow infusion pump system
US8114055B2 (en) 2005-05-10 2012-02-14 Palyon Medical (Bvi) Limited Implantable pump with infinitely variable resistor
US7637892B2 (en) * 2005-05-10 2009-12-29 Palyon Medical (Bvi) Limited Variable flow infusion pump system
US8211060B2 (en) 2005-05-10 2012-07-03 Palyon Medical (Bvi) Limited Reduced size implantable pump
US8391990B2 (en) 2005-05-18 2013-03-05 Cardiac Pacemakers, Inc. Modular antitachyarrhythmia therapy system
US20070010735A1 (en) * 2005-05-19 2007-01-11 Biophan Technologies, Inc. Electromagnetic resonant circuit sleeve for implantable medical device
US8588930B2 (en) * 2005-06-07 2013-11-19 Ethicon, Inc. Piezoelectric stimulation device
US8251904B2 (en) 2005-06-09 2012-08-28 Roche Diagnostics Operations, Inc. Device and method for insulin dosing
US7801620B2 (en) * 2005-08-29 2010-09-21 Cardiac Pacemakers, Inc. RF telemetry link quality assessment system and method
US7742815B2 (en) 2005-09-09 2010-06-22 Cardiac Pacemakers, Inc. Using implanted sensors for feedback control of implanted medical devices
US20070078497A1 (en) * 2005-10-03 2007-04-05 Vandanacker John P Remote programming of implantable medical devices
US8457742B2 (en) 2005-10-14 2013-06-04 Nanostim, Inc. Leadless cardiac pacemaker system for usage in combination with an implantable cardioverter-defibrillator
US9168383B2 (en) 2005-10-14 2015-10-27 Pacesetter, Inc. Leadless cardiac pacemaker with conducted communication
US7843328B2 (en) * 2005-11-22 2010-11-30 Covidien Ag Medical device with selectable status monitoring modes
US8725243B2 (en) 2005-12-28 2014-05-13 Cyberonics, Inc. Methods and systems for recommending an appropriate pharmacological treatment to a patient for managing epilepsy and other neurological disorders
US8868172B2 (en) 2005-12-28 2014-10-21 Cyberonics, Inc. Methods and systems for recommending an appropriate action to a patient for managing epilepsy and other neurological disorders
US9066847B2 (en) 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US9289583B2 (en) 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US8252328B2 (en) 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US20070260491A1 (en) * 2006-05-08 2007-11-08 Pamela Palmer System for delivery and monitoring of administration of controlled substances
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US20080027347A1 (en) 2006-06-23 2008-01-31 Neuro Vista Corporation, A Delaware Corporation Minimally Invasive Monitoring Methods
US20080004533A1 (en) * 2006-06-30 2008-01-03 General Electric Company Optical imaging systems and methods
US7623922B2 (en) * 2006-07-12 2009-11-24 Cardiac Pacemakers, Inc. Implantable medical device telemetry with periodic frequency hopping
US8185204B2 (en) * 2006-07-12 2012-05-22 Cardiac Pacemakers, Inc. Implantable medical device telemetry with adaptive frequency hopping
US7955268B2 (en) 2006-07-21 2011-06-07 Cardiac Pacemakers, Inc. Multiple sensor deployment
US20080077028A1 (en) * 2006-09-27 2008-03-27 Biotronic Crm Patent Personal health monitoring and care system
US20080132962A1 (en) * 2006-12-01 2008-06-05 Diubaldi Anthony System and method for affecting gatric functions
US8768486B2 (en) * 2006-12-11 2014-07-01 Medtronic, Inc. Medical leads with frequency independent magnetic resonance imaging protection
EP2126785A2 (en) 2007-01-25 2009-12-02 NeuroVista Corporation Systems and methods for identifying a contra-ictal condition in a subject
US20080183097A1 (en) 2007-01-25 2008-07-31 Leyde Kent W Methods and Systems for Measuring a Subject's Susceptibility to a Seizure
US9270025B2 (en) 2007-03-09 2016-02-23 Proteus Digital Health, Inc. In-body device having deployable antenna
US8046079B2 (en) * 2007-03-13 2011-10-25 Cardiac Pacemakers, Inc. Implantable medical device telemetry with hop-on-error frequency hopping
US8540632B2 (en) 2007-05-24 2013-09-24 Proteus Digital Health, Inc. Low profile antenna for in body device
US20080312966A1 (en) * 2007-06-13 2008-12-18 Zubin Meshginpoosh Rx SCAN SOFTWARE COMPONENT SUCH AS FOR INCORPORATION INTO A MEDICAL COMPLIANCE SOFTWARE BASED SYSTEM & COMPUTER WRITEABLE MEDIUM
US9788744B2 (en) 2007-07-27 2017-10-17 Cyberonics, Inc. Systems for monitoring brain activity and patient advisory device
CA2704929C (en) * 2007-08-07 2018-05-15 Pamela Palmer Compositions and methods for procedural sedation and analgesia using oral transmucosal dosage forms
US8352026B2 (en) 2007-10-03 2013-01-08 Ethicon, Inc. Implantable pulse generators and methods for selective nerve stimulation
US8180442B2 (en) * 2007-12-14 2012-05-15 Greatbatch Ltd. Deriving patient activity information from sensed body electrical information
US8636670B2 (en) 2008-05-13 2014-01-28 The Invention Science Fund I, Llc Circulatory monitoring systems and methods
US9717896B2 (en) 2007-12-18 2017-08-01 Gearbox, Llc Treatment indications informed by a priori implant information
US20090287120A1 (en) 2007-12-18 2009-11-19 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Circulatory monitoring systems and methods
US20090171168A1 (en) 2007-12-28 2009-07-02 Leyde Kent W Systems and Method for Recording Clinical Manifestations of a Seizure
US9259591B2 (en) 2007-12-28 2016-02-16 Cyberonics, Inc. Housing for an implantable medical device
US8725260B2 (en) 2008-02-11 2014-05-13 Cardiac Pacemakers, Inc Methods of monitoring hemodynamic status for rhythm discrimination within the heart
WO2009102640A1 (en) 2008-02-12 2009-08-20 Cardiac Pacemakers, Inc. Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices
US20090281393A1 (en) * 2008-05-08 2009-11-12 Putnam Technical Group, Inc. Method and apparatus for administering and monitoring patient treatment
US8112290B2 (en) 2008-05-16 2012-02-07 Adolor Corporation Methods for delivering a drug to a hospital patient for short-term use while minimizing long-term use of the drug
SG10201702853UA (en) 2008-07-08 2017-06-29 Proteus Digital Health Inc Ingestible event marker data framework
US10089443B2 (en) 2012-05-15 2018-10-02 Baxter International Inc. Home medical device systems and methods for therapy prescription and tracking, servicing and inventory
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
AU2009281876B2 (en) 2008-08-13 2014-05-22 Proteus Digital Health, Inc. Ingestible circuitry
JP5465252B2 (en) 2008-10-10 2014-04-09 カーディアック ペースメイカーズ， インコーポレイテッド System and method for determining cardiac output using pulmonary artery pressure measurements
US8554579B2 (en) 2008-10-13 2013-10-08 Fht, Inc. Management, reporting and benchmarking of medication preparation
EP2350969A4 (en) * 2008-10-14 2012-08-29 Proteus Biomedical Inc Method and system for incorporating physiologic data in a gaming environment
WO2010059291A1 (en) 2008-11-19 2010-05-27 Cardiac Pacemakers, Inc. Assessment of pulmonary vascular resistance via pulmonary artery pressure
US8945592B2 (en) * 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
US8849390B2 (en) 2008-12-29 2014-09-30 Cyberonics, Inc. Processing for multi-channel signals
SG196787A1 (en) 2009-01-06 2014-02-13 Proteus Digital Health Inc Ingestion-related biofeedback and personalized medical therapy method and system
US8685093B2 (en) 2009-01-23 2014-04-01 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8126736B2 (en) 2009-01-23 2012-02-28 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8527068B2 (en) 2009-02-02 2013-09-03 Nanostim, Inc. Leadless cardiac pacemaker with secondary fixation capability
US20100228566A1 (en) * 2009-03-09 2010-09-09 Gloria Taylor Portable Vital Statistics Monitoring and Medication Dispensing System
WO2010107761A1 (en) 2009-03-18 2010-09-23 Acelrx Pharmaceuticals, Inc. Improved storage and dispensing devices for administration of oral transmucosal dosage forms
GB2480965B (en) 2009-03-25 2014-10-08 Proteus Digital Health Inc Probablistic pharmacokinetic and pharmacodynamic modeling
SG10201810784SA (en) 2009-04-28 2018-12-28 Proteus Digital Health Inc Highly Reliable Ingestible Event Markers And Methods For Using The Same
US8786624B2 (en) 2009-06-02 2014-07-22 Cyberonics, Inc. Processing for multi-channel signals
US20110091544A1 (en) * 2009-10-16 2011-04-21 Acelrx Pharmaceuticals, Inc. Compositions and Methods for Mild Sedation, Anxiolysis and Analgesia in the Procedural Setting
US9643019B2 (en) 2010-02-12 2017-05-09 Cyberonics, Inc. Neurological monitoring and alerts
TWI638652B (en) 2010-04-07 2018-10-21 波提亞斯數位康健公司 Miniature ingestible device
JP2013523395A (en) * 2010-04-11 2013-06-17 プロテウス デジタル ヘルス， インコーポレイテッド Devices, systems, and methods for detection and delivery of medical doses
TWI557672B (en) 2010-05-19 2016-11-11 波提亞斯數位康健公司 Computer system and computer-implemented method to track medication from manufacturer to a patient, apparatus and method for confirming delivery of medication to a patient, patient interface device
US9060692B2 (en) 2010-10-12 2015-06-23 Pacesetter, Inc. Temperature sensor for a leadless cardiac pacemaker
CN103249452A (en) 2010-10-12 2013-08-14 内诺斯蒂姆股份有限公司 Temperature sensor for a leadless cardiac pacemaker
US9020611B2 (en) 2010-10-13 2015-04-28 Pacesetter, Inc. Leadless cardiac pacemaker with anti-unscrewing feature
WO2012071280A2 (en) 2010-11-22 2012-05-31 Proteus Biomedical, Inc. Ingestible device with pharmaceutical product
US8615310B2 (en) 2010-12-13 2013-12-24 Pacesetter, Inc. Delivery catheter systems and methods
US9126032B2 (en) 2010-12-13 2015-09-08 Pacesetter, Inc. Pacemaker retrieval systems and methods
EP2654889B1 (en) 2010-12-20 2017-03-01 Pacesetter, Inc. Leadless pacemaker with radial fixation mechanism
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
CN103827914A (en) 2011-07-21 2014-05-28 普罗秋斯数字健康公司 Mobile communication device, system, and method
US9511236B2 (en) 2011-11-04 2016-12-06 Pacesetter, Inc. Leadless cardiac pacemaker with integral battery and redundant welds
US8568360B2 (en) 2011-12-28 2013-10-29 Palyon Medical (Bvi) Limited Programmable implantable pump design
WO2013158712A1 (en) 2012-04-20 2013-10-24 Smiths Medical Asd, Inc. Medication dispensers
BR112015001388A2 (en) 2012-07-23 2017-07-04 Proteus Digital Health Inc techniques for making ingestible event markers comprising an ingestible component
EP2879758B1 (en) 2012-08-01 2018-04-18 Pacesetter, Inc. Biostimulator circuit with flying cell
US8761717B1 (en) 2012-08-07 2014-06-24 Brian K. Buchheit Safety feature to disable an electronic device when a wireless implantable medical device (IMD) is proximate
AU2013331417B2 (en) 2012-10-18 2016-06-02 Proteus Digital Health, Inc. Apparatus, system, and method to adaptively optimize power dissipation and broadcast power in a power source for a communication device
WO2014065871A2 (en) 2012-10-26 2014-05-01 Baxter Corporation Englewood Improved image acquisition for medical dose preparation system
NZ716476A (en) 2012-10-26 2018-10-26 Baxter Corp Englewood Improved work station for medical dose preparation system
TWI659994B (en) 2013-01-29 2019-05-21 美商普羅托斯數位健康公司 Highly-swellable polymeric films and compositions comprising the same
US20140275827A1 (en) * 2013-03-14 2014-09-18 Pacesetter, Inc. Method and system for deriving effectiveness of medical treatment of a patient
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
JP6511439B2 (en) 2013-06-04 2019-05-15 プロテウス デジタル ヘルス， インコーポレイテッド Systems, devices, and methods for data collection and outcome assessment
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
CN106102830B (en) 2014-01-10 2019-07-16 心脏起搏器股份公司 For improving the method and system of the communication between medical device
EP3092034B1 (en) 2014-01-10 2019-10-30 Cardiac Pacemakers, Inc. Systems for detecting cardiac arrhythmias
US9492357B2 (en) 2014-04-11 2016-11-15 DoseSmart, Inc. Personal intelligent dispenser
US10678382B2 (en) * 2014-04-22 2020-06-09 Avery Dennison Retail Information Services, Llc Methods and systems for monitoring medication compliance
US11367533B2 (en) 2014-06-30 2022-06-21 Baxter Corporation Englewood Managed medical information exchange
US9808631B2 (en) 2014-08-06 2017-11-07 Cardiac Pacemakers, Inc. Communication between a plurality of medical devices using time delays between communication pulses to distinguish between symbols
US9694189B2 (en) 2014-08-06 2017-07-04 Cardiac Pacemakers, Inc. Method and apparatus for communicating between medical devices
US9757570B2 (en) 2014-08-06 2017-09-12 Cardiac Pacemakers, Inc. Communications in a medical device system
EP3185952B1 (en) 2014-08-28 2018-07-25 Cardiac Pacemakers, Inc. Implantable cardiac rhythm system and an associated method for triggering a blanking period through a second device
US11107574B2 (en) 2014-09-30 2021-08-31 Baxter Corporation Englewood Management of medication preparation with formulary management
US11575673B2 (en) 2014-09-30 2023-02-07 Baxter Corporation Englewood Central user management in a distributed healthcare information management system
US10818387B2 (en) 2014-12-05 2020-10-27 Baxter Corporation Englewood Dose preparation data analytics
US10762753B2 (en) 2014-12-12 2020-09-01 Avery Dennison Retail Information Services, Llc Methods and systems for determining the time at which a seal was broken
MY187877A (en) 2014-12-23 2021-10-26 Acelrx Pharmaceuticals Inc Systems, devices and methods for dispensing oral transmucosal dosage forms
US9468772B2 (en) 2015-01-21 2016-10-18 Medtronic, Inc. Multi-device implantable medical device system and programming methods
EP3253450B1 (en) 2015-02-06 2021-03-24 Cardiac Pacemakers, Inc. System for treating cardiac arrhythmias
CN107206242B (en) 2015-02-06 2020-10-30 心脏起搏器股份公司 Systems and methods for safe delivery of electrical stimulation therapy
WO2016130477A2 (en) 2015-02-09 2016-08-18 Cardiac Pacemakers, Inc. Implantable medical device with radiopaque id tag
EP3265989A4 (en) 2015-03-03 2018-10-24 Baxter Corporation Englewood Pharmacy workflow management with integrated alerts
EP3265172B1 (en) 2015-03-04 2018-12-19 Cardiac Pacemakers, Inc. Systems for treating cardiac arrhythmias
CN107427222B (en) 2015-03-18 2021-02-09 心脏起搏器股份公司 Communication in a medical device system using link quality assessment
US10050700B2 (en) 2015-03-18 2018-08-14 Cardiac Pacemakers, Inc. Communications in a medical device system with temporal optimization
WO2016207206A1 (en) 2015-06-25 2016-12-29 Gambro Lundia Ab Medical device system and method having a distributed database
US10896301B2 (en) 2015-07-07 2021-01-19 Avery Dennison Retail Information Services, Llc RFID-based methods and systems for monitoring medication compliance
US10913594B2 (en) 2015-07-07 2021-02-09 Avery Dennison Retail Information Services, Llc Smart ejection trays for use with medication containers
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
WO2017031347A1 (en) 2015-08-20 2017-02-23 Cardiac Pacemakers, Inc. Systems and methods for communication between medical devices
CN108136186B (en) 2015-08-20 2021-09-17 心脏起搏器股份公司 System and method for communication between medical devices
US9968787B2 (en) 2015-08-27 2018-05-15 Cardiac Pacemakers, Inc. Spatial configuration of a motion sensor in an implantable medical device
US9956414B2 (en) 2015-08-27 2018-05-01 Cardiac Pacemakers, Inc. Temporal configuration of a motion sensor in an implantable medical device
WO2017040115A1 (en) 2015-08-28 2017-03-09 Cardiac Pacemakers, Inc. System for detecting tamponade
US10137305B2 (en) 2015-08-28 2018-11-27 Cardiac Pacemakers, Inc. Systems and methods for behaviorally responsive signal detection and therapy delivery
US10226631B2 (en) 2015-08-28 2019-03-12 Cardiac Pacemakers, Inc. Systems and methods for infarct detection
WO2017044389A1 (en) 2015-09-11 2017-03-16 Cardiac Pacemakers, Inc. Arrhythmia detection and confirmation
CN108136185B (en) 2015-10-08 2021-08-31 心脏起搏器股份公司 Apparatus and method for adjusting pacing rate in an implantable medical device
EP3389775B1 (en) 2015-12-17 2019-09-25 Cardiac Pacemakers, Inc. Conducted communication in a medical device system
US10905886B2 (en) 2015-12-28 2021-02-02 Cardiac Pacemakers, Inc. Implantable medical device for deployment across the atrioventricular septum
US10583303B2 (en) 2016-01-19 2020-03-10 Cardiac Pacemakers, Inc. Devices and methods for wirelessly recharging a rechargeable battery of an implantable medical device
US10350423B2 (en) 2016-02-04 2019-07-16 Cardiac Pacemakers, Inc. Delivery system with force sensor for leadless cardiac device
US11116988B2 (en) 2016-03-31 2021-09-14 Cardiac Pacemakers, Inc. Implantable medical device with rechargeable battery
US10286221B2 (en) 2016-04-29 2019-05-14 Medtronic, Inc. Operation of an extracardiovascular implantable cardioverter defibrillator (ICD) during implantation of another medical device
US9844675B2 (en) 2016-04-29 2017-12-19 Medtronic, Inc. Enabling and disabling anti-tachyarrhythmia pacing in a concomitant medical device system
US10668294B2 (en) 2016-05-10 2020-06-02 Cardiac Pacemakers, Inc. Leadless cardiac pacemaker configured for over the wire delivery
US10328272B2 (en) 2016-05-10 2019-06-25 Cardiac Pacemakers, Inc. Retrievability for implantable medical devices
US10512784B2 (en) 2016-06-27 2019-12-24 Cardiac Pacemakers, Inc. Cardiac therapy system using subcutaneously sensed P-waves for resynchronization pacing management
WO2018009569A1 (en) 2016-07-06 2018-01-11 Cardiac Pacemakers, Inc. Method and system for determining an atrial contraction timing fiducial in a leadless cardiac pacemaker system
US10426962B2 (en) 2016-07-07 2019-10-01 Cardiac Pacemakers, Inc. Leadless pacemaker using pressure measurements for pacing capture verification
EP3487579B1 (en) 2016-07-20 2020-11-25 Cardiac Pacemakers, Inc. System for utilizing an atrial contraction timing fiducial in a leadless cardiac pacemaker system
KR102051875B1 (en) 2016-07-22 2019-12-04 프로테우스 디지털 헬스, 인코포레이티드 Electromagnetic detection and detection of ingestible event markers
CN109562269B (en) 2016-08-19 2023-08-11 心脏起搏器股份公司 Transseptal implantable medical device
WO2018039322A1 (en) 2016-08-24 2018-03-01 Cardiac Pacemakers, Inc. Cardiac resynchronization using fusion promotion for timing management
US10780278B2 (en) 2016-08-24 2020-09-22 Cardiac Pacemakers, Inc. Integrated multi-device cardiac resynchronization therapy using P-wave to pace timing
WO2018057626A1 (en) 2016-09-21 2018-03-29 Cardiac Pacemakers, Inc. Implantable cardiac monitor
US10758737B2 (en) 2016-09-21 2020-09-01 Cardiac Pacemakers, Inc. Using sensor data from an intracardially implanted medical device to influence operation of an extracardially implantable cardioverter
EP3515553B1 (en) 2016-09-21 2020-08-26 Cardiac Pacemakers, Inc. Leadless stimulation device with a housing that houses internal components of the leadless stimulation device and functions as the battery case and a terminal of an internal battery
AU2017348094B2 (en) 2016-10-26 2022-10-13 Otsuka Pharmaceutical Co., Ltd. Methods for manufacturing capsules with ingestible event markers
EP3532159B1 (en) 2016-10-27 2021-12-22 Cardiac Pacemakers, Inc. Implantable medical device delivery system with integrated sensor
JP7038115B2 (en) 2016-10-27 2022-03-17 カーディアック ペースメイカーズ， インコーポレイテッド Implantable medical device with pressure sensor
WO2018081275A1 (en) 2016-10-27 2018-05-03 Cardiac Pacemakers, Inc. Multi-device cardiac resynchronization therapy with timing enhancements
US10413733B2 (en) 2016-10-27 2019-09-17 Cardiac Pacemakers, Inc. Implantable medical device with gyroscope
WO2018081237A1 (en) 2016-10-27 2018-05-03 Cardiac Pacemakers, Inc. Use of a separate device in managing the pace pulse energy of a cardiac pacemaker
WO2018081133A1 (en) 2016-10-27 2018-05-03 Cardiac Pacemakers, Inc. Implantable medical device having a sense channel with performance adjustment
US10434317B2 (en) 2016-10-31 2019-10-08 Cardiac Pacemakers, Inc. Systems and methods for activity level pacing
WO2018081713A1 (en) 2016-10-31 2018-05-03 Cardiac Pacemakers, Inc Systems for activity level pacing
US10583301B2 (en) 2016-11-08 2020-03-10 Cardiac Pacemakers, Inc. Implantable medical device for atrial deployment
US10632313B2 (en) 2016-11-09 2020-04-28 Cardiac Pacemakers, Inc. Systems, devices, and methods for setting cardiac pacing pulse parameters for a cardiac pacing device
US10639486B2 (en) 2016-11-21 2020-05-05 Cardiac Pacemakers, Inc. Implantable medical device with recharge coil
US10894163B2 (en) 2016-11-21 2021-01-19 Cardiac Pacemakers, Inc. LCP based predictive timing for cardiac resynchronization
US10881869B2 (en) 2016-11-21 2021-01-05 Cardiac Pacemakers, Inc. Wireless re-charge of an implantable medical device
WO2018094342A1 (en) 2016-11-21 2018-05-24 Cardiac Pacemakers, Inc Implantable medical device with a magnetically permeable housing and an inductive coil disposed about the housing
JP6781346B2 (en) 2016-11-21 2020-11-04 カーディアック ペースメイカーズ， インコーポレイテッド Leadless cardiac pacemaker with multi-mode communication
BR112019012719A2 (en) 2016-12-21 2019-11-26 Gambro Lundia Ab medical device system including information technology infrastructure having secure cluster domain supporting external domain
US11207532B2 (en) 2017-01-04 2021-12-28 Cardiac Pacemakers, Inc. Dynamic sensing updates using postural input in a multiple device cardiac rhythm management system
CN110234392B (en) 2017-01-26 2023-08-11 心脏起搏器股份公司 Leadless device with overmolded component
EP3573706A1 (en) 2017-01-26 2019-12-04 Cardiac Pacemakers, Inc. Intra-body device communication with redundant message transmission
WO2018140797A1 (en) 2017-01-26 2018-08-02 Cardiac Pacemakers, Inc. Leadless implantable device with detachable fixation
US10905872B2 (en) 2017-04-03 2021-02-02 Cardiac Pacemakers, Inc. Implantable medical device with a movable electrode biased toward an extended position
CN110740779B (en) 2017-04-03 2024-03-08 心脏起搏器股份公司 Cardiac pacemaker with pacing pulse energy modulation based on sensed heart rate
WO2019036568A1 (en) 2017-08-18 2019-02-21 Cardiac Pacemakers, Inc. Implantable medical device with a flux concentrator and a receiving coil disposed about the flux concentrator
EP3668592B1 (en) 2017-08-18 2021-11-17 Cardiac Pacemakers, Inc. Implantable medical device with pressure sensor
US11013436B2 (en) 2017-09-06 2021-05-25 Medtronic, Inc. Marker monitoring via a medical device
WO2019060302A1 (en) 2017-09-20 2019-03-28 Cardiac Pacemakers, Inc. Implantable medical device with multiple modes of operation
US11185703B2 (en) 2017-11-07 2021-11-30 Cardiac Pacemakers, Inc. Leadless cardiac pacemaker for bundle of his pacing
CN111417432A (en) 2017-12-01 2020-07-14 心脏起搏器股份公司 Leadless cardiac pacemaker with involution behavior
WO2019108837A1 (en) 2017-12-01 2019-06-06 Cardiac Pacemakers, Inc. Methods and systems for detecting atrial contraction timing fiducials within a search window from a ventricularly implanted leadless cardiac pacemaker
EP3717064B1 (en) 2017-12-01 2023-06-07 Cardiac Pacemakers, Inc. Methods and systems for detecting atrial contraction timing fiducials during ventricular filling from a ventricularly implanted leadless cardiac pacemaker
EP3717063B1 (en) 2017-12-01 2023-12-27 Cardiac Pacemakers, Inc. Systems for detecting atrial contraction timing fiducials and determining a cardiac interval from a ventricularly implanted leadless cardiac pacemaker
WO2019136148A1 (en) 2018-01-04 2019-07-11 Cardiac Pacemakers, Inc. Dual chamber pacing without beat-to-beat communication
US11529523B2 (en) 2018-01-04 2022-12-20 Cardiac Pacemakers, Inc. Handheld bridge device for providing a communication bridge between an implanted medical device and a smartphone
US11235159B2 (en) 2018-03-23 2022-02-01 Medtronic, Inc. VFA cardiac resynchronization therapy
US11400296B2 (en) 2018-03-23 2022-08-02 Medtronic, Inc. AV synchronous VfA cardiac therapy
WO2019183514A1 (en) 2018-03-23 2019-09-26 Medtronic, Inc. Vfa cardiac therapy for tachycardia
JP2022501085A (en) 2018-09-26 2022-01-06 メドトロニック，インコーポレイテッド Capturing in ventricular cardiac therapy from the atria
US11951313B2 (en) 2018-11-17 2024-04-09 Medtronic, Inc. VFA delivery systems and methods
US11679265B2 (en) 2019-02-14 2023-06-20 Medtronic, Inc. Lead-in-lead systems and methods for cardiac therapy
US11697025B2 (en) 2019-03-29 2023-07-11 Medtronic, Inc. Cardiac conduction system capture
US11213676B2 (en) 2019-04-01 2022-01-04 Medtronic, Inc. Delivery systems for VfA cardiac therapy
US11712188B2 (en) 2019-05-07 2023-08-01 Medtronic, Inc. Posterior left bundle branch engagement
US11305127B2 (en) 2019-08-26 2022-04-19 Medtronic Inc. VfA delivery and implant region detection
US11813466B2 (en) 2020-01-27 2023-11-14 Medtronic, Inc. Atrioventricular nodal stimulation
US11911168B2 (en) 2020-04-03 2024-02-27 Medtronic, Inc. Cardiac conduction system therapy benefit determination
US11813464B2 (en) 2020-07-31 2023-11-14 Medtronic, Inc. Cardiac conduction system evaluation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526166A2 (en) * 1991-07-29 1993-02-03 Albert L. Dessertine Patient compliance monitoring method and system
US5752976A (en) * 1995-06-23 1998-05-19 Medtronic, Inc. World wide patient location and data telemetry system for implantable medical devices
US5971594A (en) * 1998-03-24 1999-10-26 Innovative Medical Devices, Inc. Medication dispensing system
EP1022035A1 (en) * 1999-01-25 2000-07-26 Sun Microsystems, Inc. Communication network and devices to be implanted within a subject

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4360126A (en) 1978-10-13 1982-11-23 Weikel Maurice M Rotary dental amalgam dispenser
US4360125A (en) 1980-03-10 1982-11-23 Medtronic, Inc. Medication inventory device
US4494950A (en) * 1982-01-19 1985-01-22 The Johns Hopkins University Plural module medication delivery system
US4768177A (en) 1984-07-06 1988-08-30 Kehr Bruce A Method of and apparatus for alerting a patient to take medication
US4768176A (en) 1984-07-06 1988-08-30 Kehr Bruce A Apparatus for alerting a patient to take medication
US4617557A (en) * 1984-11-08 1986-10-14 National Patent Development Corporation Medication compliance aid for unit dose packaging
US4987897A (en) 1989-09-18 1991-01-29 Medtronic, Inc. Body bus medical device communication system
US5200891A (en) 1990-01-17 1993-04-06 Bruce A. Kehr Electronic medication dispensing method
US5752235A (en) 1990-01-17 1998-05-12 Informedix, Inc. Electronic medication monitoring and dispensing method
US5642731A (en) 1990-01-17 1997-07-01 Informedix, Inc. Method of and apparatus for monitoring the management of disease
AU4626893A (en) * 1992-09-14 1994-03-24 Aprex Corporation Contactless communication system
US5954641A (en) 1997-09-08 1999-09-21 Informedix, Inc. Method, apparatus and operating system for managing the administration of medication and medical treatment regimens
US5950632A (en) * 1997-03-03 1999-09-14 Motorola, Inc. Medical communication apparatus, system, and method
US6294999B1 (en) * 1999-12-29 2001-09-25 Becton, Dickinson And Company Systems and methods for monitoring patient compliance with medication regimens

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0526166A2 (en) * 1991-07-29 1993-02-03 Albert L. Dessertine Patient compliance monitoring method and system
US5752976A (en) * 1995-06-23 1998-05-19 Medtronic, Inc. World wide patient location and data telemetry system for implantable medical devices
US5971594A (en) * 1998-03-24 1999-10-26 Innovative Medical Devices, Inc. Medication dispensing system
EP1022035A1 (en) * 1999-01-25 2000-07-26 Sun Microsystems, Inc. Communication network and devices to be implanted within a subject

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
US8847766B2 (en) 2005-04-28 2014-09-30 Proteus Digital Health, Inc. Pharma-informatics system
US8956287B2 (en) 2006-05-02 2015-02-17 Proteus Digital Health, Inc. Patient customized therapeutic regimens
US8945005B2 (en) 2006-10-25 2015-02-03 Proteus Digital Health, Inc. Controlled activation ingestible identifier
US8855775B2 (en) 2006-11-14 2014-10-07 Cyberonics, Inc. Systems and methods of reducing artifact in neurological stimulation systems
US9444503B2 (en) 2006-11-20 2016-09-13 Proteus Digital Health, Inc. Active signal processing personal health signal receivers
US9083589B2 (en) 2006-11-20 2015-07-14 Proteus Digital Health, Inc. Active signal processing personal health signal receivers
US8858432B2 (en) 2007-02-01 2014-10-14 Proteus Digital Health, Inc. Ingestible event marker systems
US8956288B2 (en) 2007-02-14 2015-02-17 Proteus Digital Health, Inc. In-body power source having high surface area electrode
US8932221B2 (en) 2007-03-09 2015-01-13 Proteus Digital Health, Inc. In-body device having a multi-directional transmitter
US9445730B2 (en) 2007-03-21 2016-09-20 Cyberonics, Inc. Implantable systems and methods for identifying a contra-ictal condition in a subject
US8961412B2 (en) 2007-09-25 2015-02-24 Proteus Digital Health, Inc. In-body device with virtual dipole signal amplification
US9433371B2 (en) 2007-09-25 2016-09-06 Proteus Digital Health, Inc. In-body device with virtual dipole signal amplification
US9258035B2 (en) 2008-03-05 2016-02-09 Proteus Digital Health, Inc. Multi-mode communication ingestible event markers and systems, and methods of using the same
US9060708B2 (en) 2008-03-05 2015-06-23 Proteus Digital Health, Inc. Multi-mode communication ingestible event markers and systems, and methods of using the same
US9289595B2 (en) 2009-01-09 2016-03-22 Cyberonics, Inc. Medical lead termination sleeve for implantable medical devices
US8868453B2 (en) 2009-11-04 2014-10-21 Proteus Digital Health, Inc. System for supply chain management
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen

Also Published As

Publication number Publication date
US20020111542A1 (en) 2002-08-15
WO2001049364A2 (en) 2001-07-12
US6824512B2 (en) 2004-11-30
EP1246663B1 (en) 2005-02-02
DE60017943T2 (en) 2006-01-12
US6471645B1 (en) 2002-10-29
DE60017943D1 (en) 2005-03-10
EP1246663A2 (en) 2002-10-09

Similar Documents

Publication Publication Date Title
WO2001049364A3 (en) A communications system for an implantable device and a drug dispenser
WO2005009514A3 (en) A communications system for an implantable medical device and a delivery device
WO2004060043A3 (en) Advanced patient management system including interrogator/transceiver unit
WO2001047597A3 (en) Information network interrogation of an implanted device
EP1485164B1 (en) Device telemetry module with configurable physical layer for use with an implantable medical device
DE60012368T2 (en) CENTRAL NETWORK DEVICE FOR SIMPLIFYING REMOTE COLLABORATION OF MEDICAL INSTRUMENTS
EP1505816B1 (en) Data feedback loop for medical therapy adjustment
WO2005031631A3 (en) A medical device management system including a clinical system interface
US20030114885A1 (en) System and device for implementing an integrated medical device component package
WO2001022343A3 (en) Medical wellness parameters management system, apparatus and method
US20030177031A1 (en) Data management of patient medical information for use with an implantable medical device
US20070250130A1 (en) Remote Communication System with Availability Indicator for an Implantable Medical Device
WO2007070669A3 (en) Patient management device for portably interfacing with implantable medical devices and method
DK1546819T3 (en) Power management for instrumented drug packaging
EP1721282A2 (en) Advanced patient and medication therapy management system and method
ATE364873T1 (en) PATIENT DATA MONITORING SYSTEM
WO2002053213A3 (en) Drug management techniques for an implantable medical device
WO2002019247A3 (en) Patient analysis and research system and associated methods
EP1294440A2 (en) Portable extender for data transmission within a medical device communication system
CA2352198A1 (en) A medical system and a method of controlling the system for use by a patient for medical self treatment
AU2002241719A1 (en) Therapy management techniques for an implantable medical device
CN107184400A (en) A kind of intelligent reminding system for chronic's regular medicine taking
WO2003094089A3 (en) Personalization software for implanted medical device patients
FR2824933B1 (en) METHOD FOR MANAGING MEDICAL DATA OF AN ACTIVE IMPLANTABLE DEVICE SUCH AS A CARDIAC STIMULATOR, DEFIBRILATOR, CARDIOVERTER AND / OR MULTISITE DEVICE FOR THE USE OF A CARDIOLOGIST
WO2001047410A3 (en) Integrated software system for implantable medical device installation and management

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): CA JP

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

WWE Wipo information: entry into national phase

Ref document number: 2000980586

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000980586

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2000980586

Country of ref document: EP