WO2001045675A8 - Valve for osmotic devices - Google Patents

Valve for osmotic devices

Info

Publication number
WO2001045675A8
WO2001045675A8 PCT/US2000/034314 US0034314W WO0145675A8 WO 2001045675 A8 WO2001045675 A8 WO 2001045675A8 US 0034314 W US0034314 W US 0034314W WO 0145675 A8 WO0145675 A8 WO 0145675A8
Authority
WO
WIPO (PCT)
Prior art keywords
valve
osmotic
agent
beneficial agent
reservoir
Prior art date
Application number
PCT/US2000/034314
Other languages
French (fr)
Other versions
WO2001045675A3 (en
WO2001045675A2 (en
Inventor
John P Carr
James B Di Eckenhoff
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Priority to EP00984483A priority Critical patent/EP1328256B1/en
Priority to AU21095/01A priority patent/AU773354B2/en
Priority to KR1020027008287A priority patent/KR100734187B1/en
Priority to DE60023361T priority patent/DE60023361T2/en
Priority to AT00984483T priority patent/ATE306908T1/en
Priority to CA002402637A priority patent/CA2402637C/en
Publication of WO2001045675A2 publication Critical patent/WO2001045675A2/en
Publication of WO2001045675A3 publication Critical patent/WO2001045675A3/en
Publication of WO2001045675A8 publication Critical patent/WO2001045675A8/en
Priority to HK03107967A priority patent/HK1055680A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Abstract

An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.
PCT/US2000/034314 1999-12-21 2000-12-13 Valve for osmotic devices WO2001045675A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP00984483A EP1328256B1 (en) 1999-12-21 2000-12-13 Valve for osmotic devices
AU21095/01A AU773354B2 (en) 1999-12-21 2000-12-13 Valve for osmotic devices
KR1020027008287A KR100734187B1 (en) 1999-12-21 2000-12-13 Valve for osmotic device
DE60023361T DE60023361T2 (en) 1999-12-21 2000-12-13 VALVE FOR OSMOTIC DEVICES
AT00984483T ATE306908T1 (en) 1999-12-21 2000-12-13 VALVE FOR OSMOTIC DEVICES
CA002402637A CA2402637C (en) 1999-12-21 2000-12-13 Valve for osmotic devices
HK03107967A HK1055680A1 (en) 1999-12-21 2003-11-05 Valve for osmotic devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17130599P 1999-12-21 1999-12-21
US60/171,305 1999-12-21

Publications (3)

Publication Number Publication Date
WO2001045675A2 WO2001045675A2 (en) 2001-06-28
WO2001045675A3 WO2001045675A3 (en) 2002-01-03
WO2001045675A8 true WO2001045675A8 (en) 2003-05-22

Family

ID=22623268

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/034314 WO2001045675A2 (en) 1999-12-21 2000-12-13 Valve for osmotic devices

Country Status (11)

Country Link
US (2) US6508808B1 (en)
EP (1) EP1328256B1 (en)
KR (1) KR100734187B1 (en)
AT (1) ATE306908T1 (en)
AU (1) AU773354B2 (en)
CA (1) CA2402637C (en)
DE (1) DE60023361T2 (en)
DK (1) DK1328256T3 (en)
ES (1) ES2248156T3 (en)
HK (1) HK1055680A1 (en)
WO (1) WO2001045675A2 (en)

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US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
DE60023361T2 (en) * 1999-12-21 2006-04-27 Alza Corp., Mountain View VALVE FOR OSMOTIC DEVICES
US6929636B1 (en) * 2000-11-08 2005-08-16 Hewlett-Packard Development Company, L.P. Internal drug dispenser capsule medical device
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US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
BR0317421A (en) * 2002-12-19 2005-11-08 Alza Corp Stable non-aqueous single phase gels and formulations for release from an implantable device
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
AU2004227986A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
JP2006521897A (en) * 2003-03-31 2006-09-28 アルザ・コーポレーション Osmotic pump with means for dissipating internal pressure
KR20060002922A (en) * 2003-03-31 2006-01-09 알자 코포레이션 Non-aqueous single phase vehicles and formulations utilizing such vehicles
CA2545027A1 (en) * 2003-11-06 2005-05-26 Alza Corporation Modular imbibition rate reducer for use with implantable osmotic pump
US20050175701A1 (en) * 2004-02-10 2005-08-11 Alza Corporation Capillary moderator for osmotic delivery system
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
US7350479B2 (en) * 2004-09-10 2008-04-01 United States Of America As Represented By The Secretary Of The Army System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
EP2361630A1 (en) * 2005-02-03 2011-08-31 Intarcia Therapeutics, Inc Implantable drug delivery device comprising particles and an osmotic pump
US7959938B2 (en) 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
CN101453982B (en) * 2006-05-30 2011-05-04 精达制药公司 Two-piece, internal-channel osmotic delivery system flow modulator
ES2422864T3 (en) * 2006-08-09 2013-09-16 Intarcia Therapeutics, Inc Osmotic release systems and piston units
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
RU2440097C2 (en) 2007-04-23 2012-01-20 Интарсия Терапьютикс, Инк. Method of treating insulin-independent diabetes and obesity, osmotic delivery system and method for making it
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EP2240155B1 (en) 2008-02-13 2012-06-06 Intarcia Therapeutics, Inc Devices, formulations, and methods for delivery of multiple beneficial agents
US8028743B2 (en) * 2008-04-17 2011-10-04 Hewlett-Packard Development Company, L.P. Passive cooling in response to ambient environmental properties
NZ592113A (en) * 2008-10-15 2012-04-27 Intarcia Therapeutics Inc Highly concentrated drug particles, formulations, suspensions and uses thereof
WO2010135369A1 (en) * 2009-05-18 2010-11-25 Dose Medical Corporation Drug eluting ocular implant
EP3323423B1 (en) * 2009-09-28 2020-06-17 Intarcia Therapeutics, Inc Rapid establishment and/or termination of substantial steady-state drug delivery
US20110311606A1 (en) * 2010-06-18 2011-12-22 Coldren Bret A Punctal plugs with continuous or pulsatile drug release mechanism
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US20130090633A1 (en) * 2011-10-07 2013-04-11 University Of Southern California Osmotic patch pump
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
EP3302354B1 (en) 2015-06-03 2023-10-04 i2o Therapeutics, Inc. Implant placement systems
WO2017027376A1 (en) 2015-08-07 2017-02-16 Massachusetts Institute Of Technology Subcutaneous drug delivery device with manual activation and deactivation of drug release
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
JP7037490B2 (en) 2015-11-05 2022-03-16 ザ ジェネラル ホスピタル コーポレイション Intrathecal delivery of the nucleic acid sequence encoding ABCD1 for the treatment of adrenal spinal neuropathy
WO2017200943A1 (en) 2016-05-16 2017-11-23 Intarcia Therapeutics, Inc. Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
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CA3040906A1 (en) 2016-10-20 2018-04-26 Peptron, Inc. Methods of delivering a neuroprotective polypeptide to the central nervous system
KR20190104039A (en) 2017-01-03 2019-09-05 인타르시아 세라퓨틱스 인코포레이티드 Methods Including Continuous Administration of GLP-1 Receptor Agonists and Co-administration of Drugs
AU2018231249A1 (en) 2017-03-08 2019-09-26 Intarcia Therapeutics, Inc Apparatus and methods for administration of a nauseogenic compound from a drug delivery device
WO2019175844A2 (en) * 2018-03-16 2019-09-19 Noel Elman Devices and methods for controlled release of substances
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
BR112021006823A2 (en) 2018-10-11 2021-07-27 Intarcia Therapeutics, Inc. human amylin analogue polypeptides and methods of use
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods

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Also Published As

Publication number Publication date
AU773354B2 (en) 2004-05-20
CA2402637C (en) 2007-04-10
CA2402637A1 (en) 2001-06-28
DE60023361T2 (en) 2006-04-27
WO2001045675A3 (en) 2002-01-03
HK1055680A1 (en) 2004-01-21
AU2109501A (en) 2001-07-03
US20030093063A1 (en) 2003-05-15
EP1328256B1 (en) 2005-10-19
US6508808B1 (en) 2003-01-21
DK1328256T3 (en) 2006-02-20
DE60023361D1 (en) 2005-11-24
KR100734187B1 (en) 2007-07-02
ES2248156T3 (en) 2006-03-16
WO2001045675A2 (en) 2001-06-28
ATE306908T1 (en) 2005-11-15
US6682522B2 (en) 2004-01-27
EP1328256A2 (en) 2003-07-23
KR20030009336A (en) 2003-01-29

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