WO2001045550B1 - Ultrasound transducers for imaging and therapy - Google Patents

Ultrasound transducers for imaging and therapy

Info

Publication number
WO2001045550B1
WO2001045550B1 PCT/US2000/035262 US0035262W WO0145550B1 WO 2001045550 B1 WO2001045550 B1 WO 2001045550B1 US 0035262 W US0035262 W US 0035262W WO 0145550 B1 WO0145550 B1 WO 0145550B1
Authority
WO
WIPO (PCT)
Prior art keywords
ultrasound transducer
ultrasound
transducer elements
array
separate
Prior art date
Application number
PCT/US2000/035262
Other languages
French (fr)
Other versions
WO2001045550A3 (en
WO2001045550A2 (en
Inventor
Lee Weng
David Perozek
Jimin Zhang
Original Assignee
Therus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therus Corp filed Critical Therus Corp
Priority to AU25982/01A priority Critical patent/AU2598201A/en
Priority to EP00989483A priority patent/EP1241994A4/en
Priority to JP2001546292A priority patent/JP2004512856A/en
Priority to CA002394892A priority patent/CA2394892A1/en
Publication of WO2001045550A2 publication Critical patent/WO2001045550A2/en
Publication of WO2001045550A3 publication Critical patent/WO2001045550A3/en
Publication of WO2001045550B1 publication Critical patent/WO2001045550B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/4461—Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
    • A61B8/445—Details of catheter construction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0245—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with ultrasonic transducers, e.g. piezoelectric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
    • G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
    • G10K11/18—Methods or devices for transmitting, conducting or directing sound
    • G10K11/26—Sound-focusing or directing, e.g. scanning
    • G10K11/32—Sound-focusing or directing, e.g. scanning characterised by the shape of the source
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10K—SOUND-PRODUCING DEVICES; METHODS OR DEVICES FOR PROTECTING AGAINST, OR FOR DAMPING, NOISE OR OTHER ACOUSTIC WAVES IN GENERAL; ACOUSTICS NOT OTHERWISE PROVIDED FOR
    • G10K11/00—Methods or devices for transmitting, conducting or directing sound in general; Methods or devices for protecting against, or for damping, noise or other acoustic waves in general
    • G10K11/18—Methods or devices for transmitting, conducting or directing sound
    • G10K11/26—Sound-focusing or directing, e.g. scanning
    • G10K11/34—Sound-focusing or directing, e.g. scanning using electrical steering of transducer arrays, e.g. beam steering
    • G10K11/341—Circuits therefor
    • G10K11/346—Circuits therefor using phase variation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A61B2017/00504—Tissue welding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00831—Material properties
    • A61B2017/00902—Material properties transparent or translucent
    • A61B2017/00907—Material properties transparent or translucent for light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06—Measuring instruments not otherwise provided for
    • A61B2090/062—Measuring instruments not otherwise provided for penetration depth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/378—Surgical systems with images on a monitor during operation using ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3904—Markers, e.g. radio-opaque or breast lesions markers specially adapted for marking specified tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3937—Visible markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/164—Details of sensor housings or probes; Details of structural supports for sensors the sensor is mounted in or on a conformable substrate or carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0052—Ultrasound therapy using the same transducer for therapy and imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0056—Beam shaping elements
    • A61N2007/0065—Concave transducers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers

Abstract

Ultrasound applicators able to both image a treatment site and administer ultrasound therapy include an array of transducer elements (102) that can be focused. In several embodiments, an electronically phased array (102) is used for controlling the focal point of an ultrasound beam. The ultrasound beam produced thereby can also be electronically steered. To reduce the quality factor or Q of the array (102) when the array (102) is used for imaging, an electronic switch (171) is selectively closed, placing a resistance in parallel with each of the array elements (102). A flexible array (102) is employed in several embodiments and is selectively bent or flexed to vary its radius of curvature and thus control the focal point (132) and/or a direction of focus of the array (102). In another embodiment, each of the transducer elements (102) comprising the array (102) are individually mechanically pivotable to steer the ultrasonic beam produced by the transducer elements.

Claims

AM ENDED CLAIMS
[received by the International Bureau on 27 July 2001 (27.07.01); original claims 44 and 49 amended; remaining claims unchanged (2 pages)]
41. The flexible ultrasound transducer of Claim 40, further comprising a key having a plurality of surfaces that act upon the plurality of pins to define the curvature of the array and thus, the focal point of the array.
42. The flexible ultrasound transducer of Claim 41, wherein the plurality of surfaces of the key are cam shaped and wherein the key is adapted to vary the position of the pins and thereby, to vary the focus of the array as the key is moved.
43. A method for selectively controlling at least one of a direction in which an ultrasound beam is emitted by an ultrasound transducer and a focus point of the ultrasound transducer, comprising the steps of:
(a) providing a flexible transducer array that includes a plurality of ultrasound transducer elements supported on a flexible layer;
(b) energizing the plurality of ultrasound transducer elements so that they emit an ultrasound beam; and
(c) enabling a user to selectively cause the flexible transducer array to bend so that the flexible transducer array assumes a curvature that achieves at least one of a desired direction and a desired focal point for the ultrasound beam emitted by the plurality of ultrasound transducer elements.
44. An ultrasound transducer that emits an ultrasound beam toward at least one of a desired direction and a desired focal point, comprising:
(a) a plurality of separate ultrasound transducer elements that are pivotally mounted in a spaced-apart array; and
(b) a plurality of actuators coupled to the plurality of ultrasound transducer elements and adapted to independently selectively rotate the plurality of separate ultrasound transducer elements about an axis of each, thereby orienting each of the plurality of separate ultrasound transducer elements so that it is directed in a desired direction, and so that when energized, the plurality of separate ultrasound transducer elements collectively emit an ultrasound beam toward at least one of a desired direction and a desired focal point.
45. The ultrasound transducer of Claim 44, wherein each of the plurality of actuators includes a prime mover and a linkage coupled to one of the plurality of separate ultrasound transducer elements. -35 -
46. The ultrasound transducer of Claim 44, further comprising a housing in which the plurality of separate ultrasound transducer elements are disposed.
47. The ultrasound transducer of Claim 44, further comprising a plurality of leads separately coupled to each of the plurality of separate ultrasound transducer elements to provide a driving signal thereto.
48. The ultrasound transducer of Claim 44, wherein each of the plurality of separate ultrasound transducer elements comprises a composite mixture that includes a piezo ceramic, an adhesive binder, and thermally conductive particles.
49. A method of mechanically controlling at least one of a desired direction and a desired focal point of an ultrasound beam emitted by a plurality of separate ultrasound transducer elements, comprising the steps of:
(a) providing a plurality of separate ultrasound transducer elements that are pivotally mounted to rotate when actuated, each of the plurality of separate transducer elements being independently pivoted by its own actuator;
(b) actuating the plurality of separate ultrasound transducer elements so that each emit an ultrasound signal; and
(c) selectively rotating the plurality of separate ultrasound transducer elements about their respective axes so that the ultrasound signals they produce are combined in an ultrasound beam that is directed toward at least one of a desired direction and a desired focus.
50. An ultrasound applicator that is capable of both ultrasound imaging and administering ultrasound therapy to a site, comprising:
(a) a ultrasound transducer mounted in a housing;
(b) a plurality of conductors adapted to couple a control system to the ultrasound transducer, for conveying signals that energize the ultrasound transducer in one of an imaging mode and a therapy mode; and
(c) a quality factor circuit adapted to couple to the control system and connected to the ultrasound transducer, said quality factor circuit including a switch that is selectively actuated to vary a quality factor associated with the ultrasound transducer based upon whether the ultrasound transducer is operated in the imaging mode or the therapy mode.
51. The ultrasound applicator of Claim 50, wherein the ultrasound transducer is configured in a concave curved shape.
PCT/US2000/035262 1999-12-23 2000-12-22 Ultrasound transducers for imaging and therapy WO2001045550A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU25982/01A AU2598201A (en) 1999-12-23 2000-12-22 Ultrasound transducers for imaging and therapy
EP00989483A EP1241994A4 (en) 1999-12-23 2000-12-22 Ultrasound transducers for imaging and therapy
JP2001546292A JP2004512856A (en) 1999-12-23 2000-12-22 Imaging and therapeutic ultrasound transducers
CA002394892A CA2394892A1 (en) 1999-12-23 2000-12-22 Ultrasound transducers for imaging and therapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17170399P 1999-12-23 1999-12-23
US60/171,703 1999-12-23

Publications (3)

Publication Number Publication Date
WO2001045550A2 WO2001045550A2 (en) 2001-06-28
WO2001045550A3 WO2001045550A3 (en) 2001-12-13
WO2001045550B1 true WO2001045550B1 (en) 2002-05-30

Family

ID=22624813

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/035262 WO2001045550A2 (en) 1999-12-23 2000-12-22 Ultrasound transducers for imaging and therapy

Country Status (6)

Country Link
US (3) US6719694B2 (en)
EP (1) EP1241994A4 (en)
JP (1) JP2004512856A (en)
AU (1) AU2598201A (en)
CA (1) CA2394892A1 (en)
WO (1) WO2001045550A2 (en)

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US20060235300A1 (en) 2006-10-19
US6719694B2 (en) 2004-04-13
JP2004512856A (en) 2004-04-30
CA2394892A1 (en) 2001-06-28
WO2001045550A3 (en) 2001-12-13
US20050096542A1 (en) 2005-05-05
WO2001045550A2 (en) 2001-06-28
AU2598201A (en) 2001-07-03
US7063666B2 (en) 2006-06-20
EP1241994A4 (en) 2005-12-14
US20010031922A1 (en) 2001-10-18
EP1241994A2 (en) 2002-09-25

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