WO2001045548A3 - Surgical needle with weeping tip and method of use - Google Patents

Surgical needle with weeping tip and method of use Download PDF

Info

Publication number
WO2001045548A3
WO2001045548A3 PCT/US2000/034365 US0034365W WO0145548A3 WO 2001045548 A3 WO2001045548 A3 WO 2001045548A3 US 0034365 W US0034365 W US 0034365W WO 0145548 A3 WO0145548 A3 WO 0145548A3
Authority
WO
WIPO (PCT)
Prior art keywords
needle
catheter
distal portion
porous
injectate
Prior art date
Application number
PCT/US2000/034365
Other languages
French (fr)
Other versions
WO2001045548A2 (en
Inventor
Robert A Vantassel
David R Holmes Jr
Robert S Schwartz
Original Assignee
Tricardia Llc
Robert A Vantassel
David R Holmes Jr
Robert S Schwartz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tricardia Llc, Robert A Vantassel, David R Holmes Jr, Robert S Schwartz filed Critical Tricardia Llc
Priority to EP00986533A priority Critical patent/EP1239776B1/en
Priority to DE60033688T priority patent/DE60033688T2/en
Priority to JP2001546291A priority patent/JP2003517863A/en
Priority to CA002394860A priority patent/CA2394860A1/en
Priority to AU22757/01A priority patent/AU783463B2/en
Publication of WO2001045548A2 publication Critical patent/WO2001045548A2/en
Publication of WO2001045548A3 publication Critical patent/WO2001045548A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3286—Needle tip design, e.g. for improved penetration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M2025/0073—Tip designed for influencing the flow or the flow velocity of the fluid, e.g. inserts for twisted or vortex flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291—Shafts with additional lateral openings

Abstract

The invention provides surgical needles with a porous distal portion from which a liquid injectate will weep or ooze multidirectionally under injection pressure while the porous distal portion of the needle is inserted into a body surface. The porous distal portion of the needle can be fabricated from a porous carbon, metal, ceramic or polymer and preferably has a decreasing gradient of impedance to fluid flowing to the point of the needle to compensate for the falling off of injection pressure as fluid moves towards the point, thereby ensuring uniform weeping of the injectate along the injection course. The needle is adapted for attachment to a catheter or syringe. In another embodiment, a surgical assemblage is provided wherein a porous distal portion having similar fluid flow characteristics is located along the distal end of a catheter, and a needle point is attached to the distal end of the catheter (e.g., a steerable catheter) for piercing tissue. A guidance catheter can be used to direct the invention devices to a remote internal injection site. The invention devices and methods can be used to inject fluids (including those containing nucleic acids for gene therapy) into interior body walls or tissue, such as a heating heart, without substantial loss of fluid and without substantial damage to tissue caused by injectate.
PCT/US2000/034365 1999-12-20 2000-12-18 Surgical needle with weeping tip and method of use WO2001045548A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP00986533A EP1239776B1 (en) 1999-12-20 2000-12-18 Surgical needle with weeping tip
DE60033688T DE60033688T2 (en) 1999-12-20 2000-12-18 SURGICAL NEEDLE WITH TAMPERING TIP
JP2001546291A JP2003517863A (en) 1999-12-20 2000-12-18 Surgical needle with leaching tip and use thereof
CA002394860A CA2394860A1 (en) 1999-12-20 2000-12-18 Hypodermic needle with weeping tip and method of use
AU22757/01A AU783463B2 (en) 1999-12-20 2000-12-18 Hypodermic needle with weeping tip and method of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/468,688 US6241710B1 (en) 1999-12-20 1999-12-20 Hypodermic needle with weeping tip and method of use
US09/468,688 1999-12-20

Publications (2)

Publication Number Publication Date
WO2001045548A2 WO2001045548A2 (en) 2001-06-28
WO2001045548A3 true WO2001045548A3 (en) 2002-01-10

Family

ID=23860824

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/034365 WO2001045548A2 (en) 1999-12-20 2000-12-18 Surgical needle with weeping tip and method of use

Country Status (8)

Country Link
US (5) US6241710B1 (en)
EP (1) EP1239776B1 (en)
JP (1) JP2003517863A (en)
AT (1) ATE355018T1 (en)
AU (1) AU783463B2 (en)
CA (1) CA2394860A1 (en)
DE (1) DE60033688T2 (en)
WO (1) WO2001045548A2 (en)

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US9539410B2 (en) 2005-04-19 2017-01-10 Abbott Cardiovascular Systems Inc. Methods and compositions for treating post-cardial infarction damage

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US6855132B2 (en) 2005-02-15
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US6241710B1 (en) 2001-06-05
US20050288651A1 (en) 2005-12-29
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US20030130626A1 (en) 2003-07-10
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