WO2001040765A3 - Improved flow cytometer nozzle and flow cytometer sample handling methods - Google Patents

Improved flow cytometer nozzle and flow cytometer sample handling methods Download PDF

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Publication number
WO2001040765A3
WO2001040765A3 PCT/US2000/042350 US0042350W WO0140765A3 WO 2001040765 A3 WO2001040765 A3 WO 2001040765A3 US 0042350 W US0042350 W US 0042350W WO 0140765 A3 WO0140765 A3 WO 0140765A3
Authority
WO
WIPO (PCT)
Prior art keywords
nozzle
flow cytometer
single torsional
interior surface
forces
Prior art date
Application number
PCT/US2000/042350
Other languages
French (fr)
Other versions
WO2001040765A2 (en
Inventor
Kristopher S Buchanan
Lisa Herickhoff
Original Assignee
Xy Inc
Kristopher S Buchanan
Lisa Herickhoff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23804813&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2001040765(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to NZ519275A priority Critical patent/NZ519275A/en
Priority to KR1020027007131A priority patent/KR20020063584A/en
Priority to BRPI0017624A priority patent/BRPI0017624B1/en
Priority to MXPA02005488A priority patent/MXPA02005488A/en
Priority to GB0213051A priority patent/GB2372466A/en
Priority to EP00991511A priority patent/EP1238261B1/en
Priority to AU32728/01A priority patent/AU783000B2/en
Priority to AT00991511T priority patent/ATE467113T1/en
Priority to JP2001542181A priority patent/JP5019497B2/en
Application filed by Xy Inc, Kristopher S Buchanan, Lisa Herickhoff filed Critical Xy Inc
Priority to HU0300587A priority patent/HUP0300587A2/en
Priority to KR1020077011095A priority patent/KR100909862B1/en
Priority to PL00355812A priority patent/PL355812A1/en
Priority to BRPI0016121A priority patent/BRPI0016121B1/en
Priority to IL14993600A priority patent/IL149936A0/en
Priority to DE60044373T priority patent/DE60044373D1/en
Priority to DK00991511.7T priority patent/DK1238261T3/en
Priority to CA2393121A priority patent/CA2393121C/en
Publication of WO2001040765A2 publication Critical patent/WO2001040765A2/en
Publication of WO2001040765A3 publication Critical patent/WO2001040765A3/en
Priority to NO20022536A priority patent/NO20022536L/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • G01N15/01—
    • G01N15/1409—
    • G01N15/149—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • G01N2015/1413—Hydrodynamic focussing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1404—Fluid conditioning in flow cytometers, e.g. flow cells; Supply; Control of flow
    • G01N2015/1415—Control of particle position
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Abstract

An improved nozzle system for a flow cytometer and accompanying methods have been invented for a high efficiency orientation and sorting process of a flat sample and dedicates items such as equine or bovine sperm cells. This improved nozzle system comprises a nozzle (16) with a novel interior surface geometry that can both gently accelerate the cells and can include an elliptical-like, single torsional interior surface element within (c) the nozzle, i.e., a single torsional orientation nozzle (6). The elliptical-like, single torsional interior surface element (e.g.) (8, 9, 10) may have a laminar flow surface and may produce the simplest flow path for applying minimal forces which act in either an accelerative nature or orienting hydrodynamic forces, namely, the single torsional orientation forces, to orient a flat sample (16) such as animal sperm cells into a proper direction for an analyzing and efficiently sorting process in clinical use, for research and for the animal insemination industry.
PCT/US2000/042350 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods WO2001040765A2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
CA2393121A CA2393121C (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
KR1020077011095A KR100909862B1 (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
HU0300587A HUP0300587A2 (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
PL00355812A PL355812A1 (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
KR1020027007131A KR20020063584A (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
EP00991511A EP1238261B1 (en) 1999-12-03 2000-11-29 Flow cytometer sample handling method
AU32728/01A AU783000B2 (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
AT00991511T ATE467113T1 (en) 1999-12-03 2000-11-29 FLOW CYTOMETER SAMPLE HANDLING METHOD
JP2001542181A JP5019497B2 (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling method
NZ519275A NZ519275A (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
BRPI0017624A BRPI0017624B1 (en) 1999-12-03 2000-11-29 flow cytometer sample processing method
GB0213051A GB2372466A (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods
MXPA02005488A MXPA02005488A (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods.
BRPI0016121A BRPI0016121B1 (en) 1999-12-03 2000-11-29 flow cytometer device, with nozzle
IL14993600A IL149936A0 (en) 1999-12-03 2000-11-29 Flow cytometer nozzle and flow cytometer sample handling methods
DE60044373T DE60044373D1 (en) 1999-12-03 2000-11-29 DURCHFLUSSZYTOMETERPROBENBEHANDLUNGSVERFAHREN
DK00991511.7T DK1238261T3 (en) 1999-12-03 2000-11-29 Method for Treating a Flow Cytometer Sample
NO20022536A NO20022536L (en) 1999-12-03 2002-05-28 Improved nozzle for flow cytometer and methods for handling samples from flow cytometer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/454,488 1999-12-03
US09/454,488 US6263745B1 (en) 1999-12-03 1999-12-03 Flow cytometer nozzle and flow cytometer sample handling methods

Publications (2)

Publication Number Publication Date
WO2001040765A2 WO2001040765A2 (en) 2001-06-07
WO2001040765A3 true WO2001040765A3 (en) 2002-02-14

Family

ID=23804813

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/042350 WO2001040765A2 (en) 1999-12-03 2000-11-29 Improved flow cytometer nozzle and flow cytometer sample handling methods

Country Status (25)

Country Link
US (4) US6263745B1 (en)
EP (3) EP1238261B1 (en)
JP (2) JP5019497B2 (en)
KR (3) KR20020063584A (en)
CN (1) CN1402831A (en)
AR (4) AR026683A1 (en)
AT (1) ATE467113T1 (en)
AU (1) AU783000B2 (en)
BR (1) BRPI0016121B1 (en)
CA (3) CA2822851C (en)
DE (1) DE60044373D1 (en)
DK (3) DK2180307T3 (en)
ES (2) ES2342922T3 (en)
GB (1) GB2372466A (en)
HK (1) HK1143860A1 (en)
HU (1) HUP0300587A2 (en)
IL (1) IL149936A0 (en)
MX (1) MXPA02005488A (en)
NO (1) NO20022536L (en)
NZ (1) NZ519275A (en)
PL (1) PL355812A1 (en)
RU (1) RU2002117447A (en)
TW (1) TW538243B (en)
UY (1) UY26469A1 (en)
WO (1) WO2001040765A2 (en)

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