WO2001036977A3 - Identification of disease markers involving mass-based-separation - Google Patents
Identification of disease markers involving mass-based-separation Download PDFInfo
- Publication number
- WO2001036977A3 WO2001036977A3 PCT/US2000/031492 US0031492W WO0136977A3 WO 2001036977 A3 WO2001036977 A3 WO 2001036977A3 US 0031492 W US0031492 W US 0031492W WO 0136977 A3 WO0136977 A3 WO 0136977A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- identification
- separation
- disease markers
- mass
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU16152/01A AU1615201A (en) | 1999-11-16 | 2000-11-16 | Methods and compositions for identifying disease markers |
JP2001538814A JP2003528296A (en) | 1999-11-16 | 2000-11-16 | Identification of disease markers including mass-based separation |
CA002391212A CA2391212A1 (en) | 1999-11-16 | 2000-11-16 | Methods and compositions for identifying disease markers |
EP00978722A EP1240521A2 (en) | 1999-11-16 | 2000-11-16 | Identification of disease markers involving mass-based-separation |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16567399P | 1999-11-16 | 1999-11-16 | |
US60/165,673 | 1999-11-16 | ||
US17217099P | 1999-12-17 | 1999-12-17 | |
US60/172,170 | 1999-12-17 | ||
US17886000P | 2000-01-27 | 2000-01-27 | |
US60/178,860 | 2000-01-27 | ||
US20172100P | 2000-05-03 | 2000-05-03 | |
US60/201,721 | 2000-05-03 | ||
US09/709,947 US6936424B1 (en) | 1999-11-16 | 2000-11-10 | Materials and methods for detection and treatment of breast cancer |
US09/709,954 | 2000-11-10 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2001036977A2 WO2001036977A2 (en) | 2001-05-25 |
WO2001036977A3 true WO2001036977A3 (en) | 2001-11-22 |
WO2001036977A8 WO2001036977A8 (en) | 2002-01-24 |
Family
ID=30449666
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/031492 WO2001036977A2 (en) | 1999-11-16 | 2000-11-16 | Identification of disease markers involving mass-based-separation |
PCT/US2000/031483 WO2001036470A2 (en) | 1999-11-16 | 2000-11-16 | Methods and compositions for detection and treatment of breast cancer, based on breast cancer-associated polypeptides |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/031483 WO2001036470A2 (en) | 1999-11-16 | 2000-11-16 | Methods and compositions for detection and treatment of breast cancer, based on breast cancer-associated polypeptides |
Country Status (9)
Country | Link |
---|---|
US (2) | US6936424B1 (en) |
EP (2) | EP1240521A2 (en) |
JP (2) | JP2004500056A (en) |
AT (1) | ATE354588T1 (en) |
AU (2) | AU1658901A (en) |
CA (2) | CA2391212A1 (en) |
DE (1) | DE60033555T2 (en) |
ES (1) | ES2282149T3 (en) |
WO (2) | WO2001036977A2 (en) |
Families Citing this family (40)
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US6936424B1 (en) | 1999-11-16 | 2005-08-30 | Matritech, Inc. | Materials and methods for detection and treatment of breast cancer |
AUPQ886100A0 (en) * | 2000-07-19 | 2000-08-10 | Biotron Limited | Diagnostic test |
CA2320549A1 (en) * | 2000-09-25 | 2002-03-25 | Eastern Virginia Medical College | Biomarkers of transitional cell carcinoma of the bladder |
EP1425575A4 (en) * | 2001-08-03 | 2004-09-29 | Biotron Ltd | A novel cancer marker and uses therefor in the diagnosis of cancer |
US6756586B2 (en) | 2001-10-15 | 2004-06-29 | Vanderbilt University | Methods and apparatus for analyzing biological samples by mass spectrometry |
US20050092910A1 (en) * | 2001-12-08 | 2005-05-05 | Scott Geromanos | Method of mass spectrometry |
DE10296200D2 (en) * | 2001-12-21 | 2004-11-04 | Biovision Ag | Methods for diagnosing breast cancer, associated peptides and their uses |
AU2003217954A1 (en) * | 2002-03-06 | 2003-09-22 | Johns Hopkins University | Use of biomarkers to detect breast cancer |
AU2002950878A0 (en) * | 2002-08-20 | 2002-09-12 | Proteome Systems Intellectual Property Pty Ltd | Method for diagnosing disorders |
ES2291750T3 (en) | 2002-12-20 | 2008-03-01 | F. Hoffmann-La Roche Ag | USE OF NICOTINAMIDE-N-METHYLTRANSPHERASE AS A COLORRECTAL CANCER MARKER. |
EP1613966A2 (en) | 2003-04-08 | 2006-01-11 | Colotech A/S | A method for detection of colorectal cancer in human samples |
US7425700B2 (en) | 2003-05-22 | 2008-09-16 | Stults John T | Systems and methods for discovery and analysis of markers |
US20050112622A1 (en) * | 2003-08-11 | 2005-05-26 | Ring Brian Z. | Reagents and methods for use in cancer diagnosis, classification and therapy |
US20060003391A1 (en) * | 2003-08-11 | 2006-01-05 | Ring Brian Z | Reagents and methods for use in cancer diagnosis, classification and therapy |
US20050037331A1 (en) * | 2003-08-13 | 2005-02-17 | William Galbraith | Apparatuses and methods for reducing albumin in samples |
GB0320648D0 (en) * | 2003-09-03 | 2003-10-01 | Randox Lab Ltd | Molecular marker |
US20080131916A1 (en) * | 2004-08-10 | 2008-06-05 | Ring Brian Z | Reagents and Methods For Use In Cancer Diagnosis, Classification and Therapy |
EP1794593A2 (en) * | 2004-09-21 | 2007-06-13 | Matritech, Inc. | Methods and compositions for detecting cancer using components of the u2 spliceosomal particle |
JP2008535771A (en) * | 2004-12-14 | 2008-09-04 | アプレラ コーポレイション | Cationic liposome and method of using the same |
ATE501267T1 (en) | 2005-01-06 | 2011-03-15 | Eastern Virginia Med School | APOLIPOPROTEIN A-II ISOFORM AS A BIOMARKER FOR PROSTATE CANCER |
DE602006013109D1 (en) * | 2005-03-14 | 2010-05-06 | Japan Health Science Found | MARKER PROTEIN FOR USE IN THE DIAGNOSIS OF PANCREATIC CANCER |
US7749445B2 (en) | 2005-05-02 | 2010-07-06 | Bioscale, Inc. | Method and apparatus for analyzing bioprocess fluids |
US7648844B2 (en) | 2005-05-02 | 2010-01-19 | Bioscale, Inc. | Method and apparatus for detection of analyte using an acoustic device |
US20100173788A1 (en) * | 2005-06-21 | 2010-07-08 | Vermillion, Inc. | Biomarkers for breast cancer |
JP2009509169A (en) * | 2005-09-19 | 2009-03-05 | ザ・ジョンズ・ホプキンス・ユニバーシティ | Biomarkers for prostate cancer |
JP5199101B2 (en) * | 2005-10-13 | 2013-05-15 | アプライド バイオシステムズ リミテッド ライアビリティー カンパニー | Methods for developing biomolecule assays |
US9517240B2 (en) | 2006-09-26 | 2016-12-13 | The Regents Of The University Of California | Methods and compositions for cancer prevention and treatment |
US20100160275A1 (en) * | 2006-09-26 | 2010-06-24 | Lee Eva Y H P | Methods and compositions for cancer prevention and treatment |
US8354280B2 (en) | 2007-09-06 | 2013-01-15 | Bioscale, Inc. | Reusable detection surfaces and methods of using same |
WO2009075864A1 (en) * | 2007-12-11 | 2009-06-18 | New York University School Of Medicine | Methods for detecting colon carcinoma |
US8232073B2 (en) | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
US9029530B2 (en) | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
JP2013502201A (en) * | 2009-08-21 | 2013-01-24 | オンコセラピー・サイエンス株式会社 | CSTF2 as a target gene for the treatment and diagnosis of lung cancer |
AU2012261953A1 (en) * | 2011-06-03 | 2013-12-12 | University Of South Alabama | Methods and compositions for detecting endometrial or ovarian cancer |
EP3256040A4 (en) * | 2015-02-11 | 2018-08-08 | Abbott Diabetes Care Inc. | Methods, devices and systems for distinguishing cancerous and non-cancerous tissue |
US20170168055A1 (en) * | 2015-12-11 | 2017-06-15 | Expression Pathology, Inc. | SRM/MRM Assays |
EP3614909B1 (en) * | 2017-04-28 | 2024-04-03 | Masimo Corporation | Spot check measurement system |
CN107677825B (en) * | 2017-10-06 | 2019-04-23 | 汉氏联合(天津)干细胞研究院有限公司 | A kind of tumor diagnosis composition for diagnosis of cervical cancer and the purposes for being used to prepare diagnostic kit |
WO2021026172A1 (en) | 2019-08-05 | 2021-02-11 | Seer, Inc. | Systems and methods for sample preparation, data generation, and protein corona analysis |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19632521A1 (en) * | 1996-08-13 | 1998-02-19 | Forssmann Wolf Georg | Isolating peptide(s) from body fluids, tissues and cell supernatant |
WO1998007036A1 (en) * | 1996-08-13 | 1998-02-19 | Biovision Gmbh & Co. Kg | Process for determining the status of an organism by peptide measurement |
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US5561222A (en) | 1989-11-15 | 1996-10-01 | Duke University | RNA-binding proteins useful for the control of cellular genetic processing and expression |
EP0460607A3 (en) | 1990-06-05 | 1992-04-01 | Bristol-Myers Squibb Company | Novel monoclonal antibody to novel antigen associated with human tumors |
US5792664A (en) | 1992-05-29 | 1998-08-11 | The Rockefeller University | Methods for producing and analyzing biopolymer ladders |
ATE242485T1 (en) | 1993-05-28 | 2003-06-15 | Baylor College Medicine | METHOD AND MASS SPECTROMETER FOR THE DESORPTION AND IONIZATION OF ANALYTES |
NZ306653A (en) | 1995-03-23 | 1999-03-29 | Immunex Corp | Isolated dna il-17 receptors |
KR970705645A (en) | 1995-07-03 | 1997-10-09 | 에프. 지. 엠. 헤르만스/이. 에이치 리링크 | A METHOD FOR DETERMINING THE INTEGRITY OF NUCLEIC ACID |
US5962242A (en) | 1995-09-19 | 1999-10-05 | Immuna Care Corporation | Methods of predicting estrogen-dependent osteopenia |
US5798266A (en) | 1996-08-27 | 1998-08-25 | K-Quay Enterprises, Llc | Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer |
US7008778B1 (en) * | 1997-02-03 | 2006-03-07 | Human Genome Sciences, Inc. | Breast cancer specific gene 1 |
CA2284642A1 (en) | 1997-03-21 | 1998-10-01 | Musc Foundation For Research Development | Methods and compositions for diagnosis and treatment of breast cancer |
NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
WO1999039204A1 (en) | 1998-02-02 | 1999-08-05 | Novadx | Removal of abundant interfering proteins from a liquid sample using a collapsible affinity matrix |
US6410692B2 (en) | 1998-02-02 | 2002-06-25 | Novadx, Inc. | Removal of abundant interfering proteins from a liquid sample using a collapsible affinity matrix |
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US6753314B1 (en) * | 1999-04-01 | 2004-06-22 | Curagen Corporation | Protein-protein complexes and methods of using same |
US6936424B1 (en) | 1999-11-16 | 2005-08-30 | Matritech, Inc. | Materials and methods for detection and treatment of breast cancer |
EP1794593A2 (en) * | 2004-09-21 | 2007-06-13 | Matritech, Inc. | Methods and compositions for detecting cancer using components of the u2 spliceosomal particle |
-
2000
- 2000-11-10 US US09/709,947 patent/US6936424B1/en not_active Expired - Fee Related
- 2000-11-16 AU AU16589/01A patent/AU1658901A/en not_active Abandoned
- 2000-11-16 JP JP2001538959A patent/JP2004500056A/en active Pending
- 2000-11-16 CA CA002391212A patent/CA2391212A1/en not_active Abandoned
- 2000-11-16 EP EP00978722A patent/EP1240521A2/en not_active Withdrawn
- 2000-11-16 EP EP00979182A patent/EP1232177B1/en not_active Expired - Lifetime
- 2000-11-16 WO PCT/US2000/031492 patent/WO2001036977A2/en not_active Application Discontinuation
- 2000-11-16 JP JP2001538814A patent/JP2003528296A/en not_active Withdrawn
- 2000-11-16 CA CA002390607A patent/CA2390607A1/en not_active Abandoned
- 2000-11-16 ES ES00979182T patent/ES2282149T3/en not_active Expired - Lifetime
- 2000-11-16 DE DE60033555T patent/DE60033555T2/en not_active Expired - Fee Related
- 2000-11-16 AU AU16152/01A patent/AU1615201A/en not_active Abandoned
- 2000-11-16 WO PCT/US2000/031483 patent/WO2001036470A2/en active IP Right Grant
- 2000-11-16 AT AT00979182T patent/ATE354588T1/en not_active IP Right Cessation
-
2005
- 2005-07-29 US US11/194,051 patent/US20060160154A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19632521A1 (en) * | 1996-08-13 | 1998-02-19 | Forssmann Wolf Georg | Isolating peptide(s) from body fluids, tissues and cell supernatant |
WO1998007036A1 (en) * | 1996-08-13 | 1998-02-19 | Biovision Gmbh & Co. Kg | Process for determining the status of an organism by peptide measurement |
Non-Patent Citations (6)
Title |
---|
CHONG BATHSHEBA E ET AL: "Rapid screening of protein profiles of human breast cancer cell lines using non-porous reversed-phase high performance liquid chromatography separation with matrix-assisted laser desorption/ionization time-of-flight mass spectral analysis.", RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 13, no. 18, 1999, pages 1808 - 1812, XP001006015, ISSN: 0951-4198 * |
HABETS W J ET AL: "ANALYSIS OF A COMPLEMENTARY DNA CLONE EXPRESSING A HUMAN AUTOIMMUNE ANTIGEN FULL-LENGTH SEQUENCE OF THE U2 SMALL NUCLEAR RNA-ASSOCIATED B ANTIGEN", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 84, no. 8, 1987, 1987, pages 2421 - 2425, XP002169270, ISSN: 0027-8424 * |
JUNGBLUT P R ET AL: "PROTEOMICS IN HUMAN DISEASE: CANCER, HEART AND INFECTIOUS DISEASES", ELECTROPHORESIS,DE,WEINHEIM, vol. 20, no. 10, July 1999 (1999-07-01), pages 2100 - 2110, XP000870393, ISSN: 0173-0835 * |
RASMUSSEN HANNE H ET AL: "Towards a comprehensive database of proteins from the urine of patients with bladder cancer.", JOURNAL OF UROLOGY, vol. 155, no. 6, 1996, pages 2113 - 2119, XP001006003, ISSN: 0022-5347 * |
WATKINS B ET AL: "Identification of serum nuclear matrix protein markers of breast cancer using surface enhanced laser desorption-ionization (SELDI) mass spectroscopy.", BREAST CANCER RESEARCH AND TREATMENT, vol. 64, no. 1, November 2000 (2000-11-01), 23rd Annual San Antonia Breast Cancer Symposium;San antonio, Texas, USA; December 06-09, 2000, pages 98, XP001001191, ISSN: 0167-6806 * |
WATKINS B ET AL: "Surface enhanced laser desorption-ionization (SELDI) mass spectroscopy in the discovery of serum markers for breast cancer.", TUMOR BIOLOGY, vol. 21, no. Supplement 1, September 2000 (2000-09-01), 28th Meeting of the International Society for Oncodevelopmental Biology and Medicine;Munich, Germany; September 08-13, 2000, pages 35, XP001001193, ISSN: 1010-4283 * |
Also Published As
Publication number | Publication date |
---|---|
US20060160154A1 (en) | 2006-07-20 |
CA2390607A1 (en) | 2001-05-25 |
JP2004500056A (en) | 2004-01-08 |
ATE354588T1 (en) | 2007-03-15 |
EP1232177A2 (en) | 2002-08-21 |
US6936424B1 (en) | 2005-08-30 |
WO2001036977A2 (en) | 2001-05-25 |
AU1615201A (en) | 2001-05-30 |
WO2001036470A2 (en) | 2001-05-25 |
WO2001036470A3 (en) | 2002-01-24 |
EP1240521A2 (en) | 2002-09-18 |
AU1658901A (en) | 2001-05-30 |
ES2282149T3 (en) | 2007-10-16 |
DE60033555D1 (en) | 2007-04-05 |
DE60033555T2 (en) | 2007-11-29 |
WO2001036977A8 (en) | 2002-01-24 |
EP1232177B1 (en) | 2007-02-21 |
JP2003528296A (en) | 2003-09-24 |
CA2391212A1 (en) | 2001-05-25 |
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