WO2001019178A1 - Method for marking an animal and products derived therefrom - Google Patents
Method for marking an animal and products derived therefrom Download PDFInfo
- Publication number
- WO2001019178A1 WO2001019178A1 PCT/DE2000/002997 DE0002997W WO0119178A1 WO 2001019178 A1 WO2001019178 A1 WO 2001019178A1 DE 0002997 W DE0002997 W DE 0002997W WO 0119178 A1 WO0119178 A1 WO 0119178A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- animal
- substance
- transponder
- marking
- housing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K11/00—Marking of animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K11/00—Marking of animals
- A01K11/006—Automatic identification systems for animals, e.g. electronic devices, transponders for animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K11/00—Marking of animals
- A01K11/006—Automatic identification systems for animals, e.g. electronic devices, transponders for animals
- A01K11/007—Boluses
Definitions
- the invention relates to a method for marking an animal and products derived therefrom, a transponder and a kit.
- livestock such as cattle and pigs
- a marking such as an ear tag, a tattoo or a transponder, for detection and proof of origin.
- Transponders e.g. are known from US 5,697,384, are injected at various points in the animal body under the skin or into the muscle tissue.
- the detection of a transponder is based on the following principle: an electromagnetic field is emitted into the surroundings by a readout unit using an antenna. If the transponder reaches the area of the field, it generates a current in the transponder by inductive coupling. The electricity is used to send out a signal using an antenna. The signal is detected by the readout unit and decoded. No additional energy supply is required to operate such passive transponders, e.g. in the form of a battery, necessary.
- a disadvantage of these conventional transponders is the short interrogation distance, which is generally 30-50 cm, so that even a slight displacement of the transponder in the animal can lead to errors when reading out.
- DE 37 45 053 To counteract a shift, it is known from DE 37 45 053 to cover the transponder with a roughened plastic layer.
- Another disadvantage of the above-mentioned markings is that after the animal has been separated from the markings, for example after slaughtering and cutting the animal, it is no longer possible to assign individual parts of the animal to the respective slaughtered animal.
- a biological marking for slaughter animals is known from WO 98/18003 and WO 99/36775. At least one immunogen which is harmless to the animal and the consumer is administered to the animal. The detection of the induced specific antibodies enables a tamper-proof proof of origin of the living animal and products derived from it, such as meat and meat products. The disadvantage of this method is that a sample has to be taken from the animal to prove its origin.
- the object of the invention is to eliminate the disadvantages of the prior art.
- a reliable, fast and forgery-proof marking of an animal is to be made possible.
- the marking should be as identifiable as possible without a sample having to be taken from the animal.
- a reliable and tamper-proof proof should be made possible, with which the origin of the products derived from it can be clearly determined after the animal has been slaughtered.
- a method for marking an animal and products derived therefrom in which a transponder is introduced into the animal's body and the animal receives at least one as neither a vaccine nor via the local chain chains, still reaching the environment in the usual animal husbandry in the animal's organism, triggering an immune reaction substance is applied, so that biological and physical marking is achieved simultaneously for a predetermined period of time.
- the immune reaction triggered by the substance usually does not take place in the animals because they do not come into contact with the substances triggering this immune reaction.
- care must be taken to ensure that it does not enter the animal's organism either as a vaccine, via the food chain or via the environment in normal animal husbandry.
- the substance should be safe for both the animal and the consumer.
- the method according to the invention has the advantage that at least for a predetermined period of time the immune reaction creates a biological marker which is inseparably linked to the animal.
- the biological label cannot be exchanged or forged; it cannot be removed by removing the transponder as prescribed during slaughter and cutting.
- the biological marking can be detected both in parts of the animal and in products derived from it. Detection is possible, for example, in the blood, milk or other body secretions of the animal or in the dripping or pressed juice of the meat.
- the transponder creates the possibility of identifying the animal reliably, quickly and without contact using physical methods. Counterfeit protection is achieved in particular by double marking - physical and biological.
- the immune reaction can be delayed after application of the substance.
- the marked animal can already be identified using the transponder.
- the animal is biologically and physically marked in a given period of time, for example at least 6 months before slaughter.
- the specified time period can of course also be longer than 6 months. It preferably begins a few days after the substance has been applied and extends until the animal is slaughtered.
- the transponder and the substance can be applied in one and the same work step.
- a suitably prepared transponder can also be applied.
- the double marking of the animal ensures significantly increased security.
- the origin of the animal can nevertheless be proven by the biological marking.
- the transponder enables an unambiguous identification of an animal in which, for some reason, there has been no or an insufficient immune reaction against the substance.
- the substance can be coupled to a carrier and can be applied together with auxiliary substances, such as, for example, additional adjuvants, in solution, as a suspension or as an implant. the.
- auxiliary substances such as, for example, additional adjuvants, in solution, as a suspension or as an implant. the.
- the administration of a mixture of the substances is also provided.
- a housing of the transponder is coated with the substance.
- the substance can be absorbed by adsorptive chemicals such as e.g. Biopolymers bound to the material. It is advantageous here that an adjuvant effect can be achieved by the adsorption, which leads to an increased immune response.
- the substance can also be bound to the housing via an intermediate layer.
- the binding can e.g. via binding mediating agents, e.g. Biotin done.
- the intermediate layer can e.g. consist of polystyrene or polycarbonate.
- An adjuvant effect can be achieved by binding. It can also cause the substance to be released slowly in the animal's body. This causes a strong and lasting stimulation of the immune response.
- the substance is encased and / or embedded in an agent which delays accessibility in the body of the animal.
- an implantation can be carried out in the perinatal period, e.g. in connection with other treatments that are usually to be carried out.
- Antibody formation is delayed and e.g. only induced after a few weeks.
- Another possibility is to provide several layers with intermediate delaying means. Repeated release of the substance over a long longer period possible, so that the multiple stimulation of the immune response achieves a high, long-term antibody titre.
- Another advantage of a multi-layer structure is that different substances can be used. Through a gradual release of these substances over the lifetime of the animal, biological marking can then also take place, by means of which the age of the animal can be determined both on the living animal and on individual products derived from the animal, such as meat and meat products.
- Accessibility-delaying agents include, for example, polyglycolic acid, polydioxanone, polyglycolides, polylactides, homo- and / or copolymers of glycolides and D- / L-lactides and / or other biodegradable constituents, as described in US Pat. No. 3,887,699, US Pat. No. 3,991,766 , US 4,045,418 and US 4,137,921 can be used. The disclosure content of the US patents mentioned is hereby incorporated.
- the transponder sends a digital specific code with suitable excitation.
- a transponder that contains a digital circuit. This enables error-free detection of the transponder's signal with a lower transmission power at the same time.
- the code can be read from longer distances.
- the digital code can contain information about the biological marking of the animal. This further increases the security against forgery. A transponder cannot be transplanted into another animal's body without being noticed.
- the substance can contain peptides and / or nucleic acids. It can trigger an immune response both directly and indirectly.
- Substances that directly trigger an immune response are, for example, proteins or peptides or fragments thereof, such as: "keyhole limpet hemocyanine", "green fluorescent protein” from Aequoria victoria, inactive snake toxins, virus proteins, hirudin, phero onotropin, renalexin and artificial proteins and peptides, the amino acid sequence of which no previously known substance corresponds, which are harmless for the animal and the consumer.
- Particularly suitable peptides are those with at least one non-physiological amino acid, a modified amino acid, a D-amino acid and / or a derivative of such an amino acid.
- Modified amino acids and derivatives can contain, for example, selenium, alkyl, phenyl or other radicals or carbohydrates.
- peptides containing at least one non-physiological amino acid are that it can be used to provide substances with which the animals to be labeled have not previously come into contact.
- these amino acids offer the advantage that a large number of different peptides can be provided by combining them. Individual marking of individual animals is possible.
- the amino acids mentioned can be used to provide peptides which are more stable in the animal body than peptides with naturally occurring amino acids. A particularly long-lasting immune stimulation and an improved antibody titer can be achieved.
- vaccines suitable or appropriately prepared for labeling purposes are also regarded as substances suitable for labeling.
- the nucleic acids can be contained in an expression vector. You can code for a particular immunogen. Such an immunogen can be, for example, one of the proteins or peptides specified above. An immune response can be triggered indirectly by the application of the nucleic acids.
- the substance can also be a chemical agent or a chemical group, such as the dinitrophenyl group.
- Chemical agents or chemical groups often have to be coupled to larger molecules in order to be immunogenic.
- the dinitrophenyl group can e.g. are coupled to a protein such as bovine serum albumin and thereby become immunogenic.
- a code is expediently read from the transponder by means of an external transmission and detector device.
- an external transmission and detector device In this way, it is possible, for example, to provide farm animals with feed and certain additives individually at a feeder in a farm or to quickly determine the origin of individual animals when they are driven through.
- the method also enables the mechanical recording of the origin of animals which have already been slaughtered and which still contain the transponder, so that processing which is dependent on the origin can be controlled automatically in a cutting operation, for example.
- the invention furthermore relates to a method for verifying the origin of an animal marked by a method according to the invention, the antibodies and / or T cells and / or their receptors specifically formed by the substance being derived from a body fluid of the animal, from milk or from the drip juice meat derived therefrom can be detected.
- a method for the detection of antibodies has the advantage that it can be carried out easily and quickly at any time.
- the invention further relates to a transponder, the housing of which is coated with a substance which triggers an immune reaction in the animal and which does not enter the animal's organism either as a vaccine, nor via the food chain or via the environment in the normal manner of animal husbandry.
- the transponder advantageously has a digital circuit for sending a digital code. Such transponders have a low power consumption. They can be read from a relatively large distance.
- the invention further relates to a kit with a transponder and at least one substance which triggers an immune reaction in an animal and which does not enter the animal's organism either as a vaccine, via the food chain or via the environment in the normal manner of animal husbandry. Because of the advantageous embodiments, reference is made to the previous explanations. It goes without saying that the features mentioned above and those yet to be explained below can be used not only in the respectively specified combinations but also in other combinations or on their own without departing from the scope of the present invention.
- Fig. 1 is a schematic sectional view of a first embodiment
- Fig. 2 is a schematic sectional view of a second embodiment.
- a general transponder device designated T has a transponder 10 with a housing 14, which is expediently made of a dielectric and biologically inert material. It can be glass, polyethylene, polystyrene or polycarbonate.
- the housing 14 is coated with a substance 16.
- the substance 16 is enveloped by a means 18 which delays or retards the accessibility in the body of the animal. It can e.g. are polyglycolic acid.
- the substance 16 is bound to the housing 14 via an intermediate layer 15.
- the intermediate layer can e.g. be made of polystyrene or polycarbonate.
- the transponder device T is introduced into an animal to be marked, for example by being injected intramuscularly.
- the retarding agent 18 consisting of polyglycolic acid, for example, dissolves.
- substance 16, which can be, for example, "keyhole limpet hemocyanine” becomes accessible to the animal's immune system and directly or indirectly causes an immune response in the animal.
- the substance 16 can be released slowly, ie over the entire life of the animal, so that the animal has a high antibody titre for a long time.
- the substance 16 can be bound to the surface of the housing 14 directly or via adsorptive chemicals.
- the transponder 10 can contain a digital circuit that generates a specific digital code and thus enables a greater query distance than conventional transponders. As long as the animal body marked in this way contains the transponder 10, it can be detected by means of a corresponding transmitter and detector device. After slaughtering and cutting the animal, the antibodies formed against substance 16 can be detected, for example, in the dripping juice of the meat of the slaughtered animal. This can be done, for example, by an ELISA, in which substance 16 was immobilized on a microtiter plate. The antibodies from the dripping juice of the meat that bind to it can then be detected by binding enzyme-labeled secondary antibodies, which are directed against antibodies of the animal, and a corresponding enzyme reaction.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00965809A EP1211930A1 (en) | 1999-09-15 | 2000-08-31 | Method for marking an animal and products derived therefrom |
PL00354312A PL354312A1 (en) | 1999-09-15 | 2000-08-31 | Method for marking an animal and products derived therefrom |
CA002386520A CA2386520A1 (en) | 1999-09-15 | 2000-08-31 | Method for marking an animal and products derived therefrom |
AU76436/00A AU7643600A (en) | 1999-09-15 | 2000-08-31 | Method for marking an animal and products derived therefrom |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19944128A DE19944128A1 (en) | 1999-09-15 | 1999-09-15 | Process for marking an animal and products derived from it |
DE19944128.6 | 1999-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001019178A1 true WO2001019178A1 (en) | 2001-03-22 |
Family
ID=7922050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2000/002997 WO2001019178A1 (en) | 1999-09-15 | 2000-08-31 | Method for marking an animal and products derived therefrom |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1211930A1 (en) |
AR (1) | AR025681A1 (en) |
AU (1) | AU7643600A (en) |
CA (1) | CA2386520A1 (en) |
CZ (1) | CZ2002905A3 (en) |
DE (1) | DE19944128A1 (en) |
PL (1) | PL354312A1 (en) |
WO (1) | WO2001019178A1 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10130321A1 (en) * | 2001-06-22 | 2003-01-09 | Hans-Lorenz Werner | Identifying individuals, useful for preventing falsification of urine samples, comprises administering a marker that can be detected in body fluids |
CN100350832C (en) * | 2005-02-23 | 2007-11-28 | 余向明 | Anti-fake method for live fowls mark |
WO2008052298A1 (en) * | 2006-10-30 | 2008-05-08 | Romano Jorge Alberto | Traceability process and security elements used in said process |
NL2012303C2 (en) * | 2014-02-21 | 2015-08-25 | Lely Patent Nv | SYSTEM AND METHOD FOR MONITORING AN ANIMAL. |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3887699A (en) | 1969-03-24 | 1975-06-03 | Seymour Yolles | Biodegradable polymeric article for dispensing drugs |
US3991766A (en) | 1973-05-31 | 1976-11-16 | American Cyanamid Company | Controlled release of medicaments using polymers from glycolic acid |
US4045418A (en) | 1975-01-28 | 1977-08-30 | Gulf Oil Corporation | Copolymers of D,L-lactide and epsilon caprolactone |
US4137921A (en) | 1977-06-24 | 1979-02-06 | Ethicon, Inc. | Addition copolymers of lactide and glycolide and method of preparation |
US4152412A (en) * | 1976-04-02 | 1979-05-01 | Brewer John H | Marking vaccine |
DE3745053C2 (en) | 1986-10-06 | 1995-04-27 | Bio Medic Data Systems Inc | Marking device for animals |
US5697384A (en) | 1993-03-26 | 1997-12-16 | Surge Miyawaki Co., Ltd. | Internal identification apparatus for animals |
WO1998018003A2 (en) | 1996-10-23 | 1998-04-30 | Manfred Gareis | Method of establishing the origin of useful animals and products produced therefrom |
WO1998047351A1 (en) * | 1997-04-18 | 1998-10-29 | Avid Identification Syst Inc | Animal husbandry system |
WO1999036775A1 (en) | 1998-01-14 | 1999-07-22 | November Aktiengesellschaft_Gesellschaft Für Molekulare Medizin | Method for detecting the origin of livestock and the products obtained therefrom |
-
1999
- 1999-09-15 DE DE19944128A patent/DE19944128A1/en not_active Ceased
-
2000
- 2000-08-31 WO PCT/DE2000/002997 patent/WO2001019178A1/en not_active Application Discontinuation
- 2000-08-31 EP EP00965809A patent/EP1211930A1/en not_active Withdrawn
- 2000-08-31 PL PL00354312A patent/PL354312A1/en not_active Application Discontinuation
- 2000-08-31 AU AU76436/00A patent/AU7643600A/en not_active Abandoned
- 2000-08-31 CA CA002386520A patent/CA2386520A1/en not_active Abandoned
- 2000-08-31 CZ CZ2002905A patent/CZ2002905A3/en unknown
- 2000-09-15 AR ARP000104847A patent/AR025681A1/en unknown
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3887699A (en) | 1969-03-24 | 1975-06-03 | Seymour Yolles | Biodegradable polymeric article for dispensing drugs |
US3991766A (en) | 1973-05-31 | 1976-11-16 | American Cyanamid Company | Controlled release of medicaments using polymers from glycolic acid |
US4045418A (en) | 1975-01-28 | 1977-08-30 | Gulf Oil Corporation | Copolymers of D,L-lactide and epsilon caprolactone |
US4152412A (en) * | 1976-04-02 | 1979-05-01 | Brewer John H | Marking vaccine |
US4137921A (en) | 1977-06-24 | 1979-02-06 | Ethicon, Inc. | Addition copolymers of lactide and glycolide and method of preparation |
DE3745053C2 (en) | 1986-10-06 | 1995-04-27 | Bio Medic Data Systems Inc | Marking device for animals |
US5697384A (en) | 1993-03-26 | 1997-12-16 | Surge Miyawaki Co., Ltd. | Internal identification apparatus for animals |
WO1998018003A2 (en) | 1996-10-23 | 1998-04-30 | Manfred Gareis | Method of establishing the origin of useful animals and products produced therefrom |
WO1998047351A1 (en) * | 1997-04-18 | 1998-10-29 | Avid Identification Syst Inc | Animal husbandry system |
WO1999036775A1 (en) | 1998-01-14 | 1999-07-22 | November Aktiengesellschaft_Gesellschaft Für Molekulare Medizin | Method for detecting the origin of livestock and the products obtained therefrom |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10130321A1 (en) * | 2001-06-22 | 2003-01-09 | Hans-Lorenz Werner | Identifying individuals, useful for preventing falsification of urine samples, comprises administering a marker that can be detected in body fluids |
CN100350832C (en) * | 2005-02-23 | 2007-11-28 | 余向明 | Anti-fake method for live fowls mark |
WO2008052298A1 (en) * | 2006-10-30 | 2008-05-08 | Romano Jorge Alberto | Traceability process and security elements used in said process |
NL2012303C2 (en) * | 2014-02-21 | 2015-08-25 | Lely Patent Nv | SYSTEM AND METHOD FOR MONITORING AN ANIMAL. |
WO2015126240A1 (en) * | 2014-02-21 | 2015-08-27 | Lely Patent N.V. | System and method for monitoring of an animal |
Also Published As
Publication number | Publication date |
---|---|
AU7643600A (en) | 2001-04-17 |
CA2386520A1 (en) | 2001-03-22 |
PL354312A1 (en) | 2004-01-12 |
CZ2002905A3 (en) | 2003-01-15 |
AR025681A1 (en) | 2002-12-11 |
DE19944128A1 (en) | 2001-04-12 |
EP1211930A1 (en) | 2002-06-12 |
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