WO2001018252A3 - Methods for disease detection - Google Patents

Methods for disease detection Download PDF

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Publication number
WO2001018252A3
WO2001018252A3 PCT/US2000/024639 US0024639W WO0118252A3 WO 2001018252 A3 WO2001018252 A3 WO 2001018252A3 US 0024639 W US0024639 W US 0024639W WO 0118252 A3 WO0118252 A3 WO 0118252A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
disease detection
sample
integrity
analysis
Prior art date
Application number
PCT/US2000/024639
Other languages
French (fr)
Other versions
WO2001018252A2 (en
Inventor
Anthony P Shuber
Original Assignee
Exact Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exact Lab Inc filed Critical Exact Lab Inc
Priority to EP00968342A priority Critical patent/EP1212468B1/en
Priority to CA002384368A priority patent/CA2384368A1/en
Priority to AT00968342T priority patent/ATE438737T1/en
Priority to AU78276/00A priority patent/AU7827600A/en
Priority to JP2001521786A priority patent/JP2003508083A/en
Priority to DE60042695T priority patent/DE60042695D1/en
Publication of WO2001018252A2 publication Critical patent/WO2001018252A2/en
Publication of WO2001018252A3 publication Critical patent/WO2001018252A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes

Abstract

The present invention provides methods for detecting disease, specially cancer, by analysis of a patient sample to determine the integrity of nucleic acids in the sample.
PCT/US2000/024639 1999-09-08 2000-09-08 Methods for disease detection WO2001018252A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP00968342A EP1212468B1 (en) 1999-09-08 2000-09-08 Methods for disease detection
CA002384368A CA2384368A1 (en) 1999-09-08 2000-09-08 Method of detecting or screening cancer or precancer by determining the amount and integrity of nucleic acids
AT00968342T ATE438737T1 (en) 1999-09-08 2000-09-08 METHOD FOR DETECTING DISEASES
AU78276/00A AU7827600A (en) 1999-09-08 2000-09-08 Methods for disease detection
JP2001521786A JP2003508083A (en) 1999-09-08 2000-09-08 Methods for disease detection
DE60042695T DE60042695D1 (en) 1999-09-08 2000-09-08 METHOD FOR DETECTING DISEASES

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15284799P 1999-09-08 1999-09-08
US60/152,847 1999-09-08
US09/455,950 US6586177B1 (en) 1999-09-08 1999-12-07 Methods for disease detection
US09/455,950 1999-12-07

Publications (2)

Publication Number Publication Date
WO2001018252A2 WO2001018252A2 (en) 2001-03-15
WO2001018252A3 true WO2001018252A3 (en) 2001-10-25

Family

ID=26849911

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/024639 WO2001018252A2 (en) 1999-09-08 2000-09-08 Methods for disease detection

Country Status (9)

Country Link
US (4) US6586177B1 (en)
EP (2) EP2110442A1 (en)
JP (2) JP2003508083A (en)
AT (1) ATE438737T1 (en)
AU (1) AU7827600A (en)
CA (1) CA2384368A1 (en)
DE (1) DE60042695D1 (en)
ES (1) ES2329543T3 (en)
WO (1) WO2001018252A2 (en)

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