WO2001001963A8 - A method for the improvement of transport across adaptable semi-permeable barriers - Google Patents

A method for the improvement of transport across adaptable semi-permeable barriers

Info

Publication number
WO2001001963A8
WO2001001963A8 PCT/EP2000/006367 EP0006367W WO0101963A8 WO 2001001963 A8 WO2001001963 A8 WO 2001001963A8 EP 0006367 W EP0006367 W EP 0006367W WO 0101963 A8 WO0101963 A8 WO 0101963A8
Authority
WO
WIPO (PCT)
Prior art keywords
penetrants
barrier
pores
transport
improvement
Prior art date
Application number
PCT/EP2000/006367
Other languages
French (fr)
Other versions
WO2001001963A1 (en
Inventor
Gregor Cevc
Holger Richardsen
Andrea Weiland-Waibel
Original Assignee
Idea Ag
Gregor Cevc
Holger Richardsen
Weiland Waibel Andrea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8167360&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2001001963(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to AU61557/00A priority Critical patent/AU779765B2/en
Priority to BR0012178-9A priority patent/BR0012178A/en
Priority to EEP200200008A priority patent/EE200200008A/en
Application filed by Idea Ag, Gregor Cevc, Holger Richardsen, Weiland Waibel Andrea filed Critical Idea Ag
Priority to PL00352380A priority patent/PL352380A1/en
Priority to EP00947939A priority patent/EP1189598A1/en
Priority to JP2001507458A priority patent/JP2003503442A/en
Priority to CA002375157A priority patent/CA2375157A1/en
Priority to HU0201454A priority patent/HUP0201454A3/en
Publication of WO2001001963A1 publication Critical patent/WO2001001963A1/en
Publication of WO2001001963A8 publication Critical patent/WO2001001963A8/en
Priority to HR20010881A priority patent/HRP20010881A2/en
Priority to US10/037,480 priority patent/US7459171B2/en
Priority to NO20020032A priority patent/NO20020032L/en
Priority to HK02106448.3A priority patent/HK1046356A1/en
Priority to US10/984,450 priority patent/US7591949B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

The invention relates to a method, a kit and a device for controlling the flux of penetrants across an adaptable semi-permeable porous barrier, the method comprising the steps of: preparing a formulation by suspending or dispersing said penetrants in a polar liquid in the form of fluid droplets surrounded by a membrane-like coating of one or several layers, said coating comprising at least two kinds of forms of amphiphilic substances with a tendency to aggregate, said penetrants being able to transport agents through the pores of said barrier or to enable agent permeation through the pores of said barrier after penetrants have entered the pores, selecting a dose amount of said penetrants to be applied on a predetermined area of said barrier to control the flux of said penetrants across said barrier, and applying the selected dose amount of said formulation containing said penetrants onto said area of said porous barrier.
PCT/EP2000/006367 1999-07-05 2000-07-05 A method for the improvement of transport across adaptable semi-permeable barriers WO2001001963A1 (en)

Priority Applications (13)

Application Number Priority Date Filing Date Title
HU0201454A HUP0201454A3 (en) 1999-07-05 2000-07-05 A method for the improvement of transport across adaptable semi-permeable barriers
EP00947939A EP1189598A1 (en) 1999-07-05 2000-07-05 A method for the improvement of transport across adaptable semi-permeable barriers
BR0012178-9A BR0012178A (en) 1999-07-05 2000-07-05 Process for improved transportation through adaptable semi-permeable barriers
EEP200200008A EE200200008A (en) 1999-07-05 2000-07-05 A method for improving transport through adaptive semipermeable barriers
CA002375157A CA2375157A1 (en) 1999-07-05 2000-07-05 A method for the improvement of transport across adaptable semi-permeable barriers
PL00352380A PL352380A1 (en) 1999-07-05 2000-07-05 Method od improved transfer through adaptable semi-permeable barriers
JP2001507458A JP2003503442A (en) 1999-07-05 2000-07-05 Methods to improve transport across adaptive semi-permeable barriers
AU61557/00A AU779765B2 (en) 1999-07-05 2000-07-05 A method for the improvement of transport across adaptable semi-permeable barriers
HR20010881A HRP20010881A2 (en) 1999-07-05 2001-11-27 A method for the improvement of transport across adaptable semi-permeable barriers
NO20020032A NO20020032L (en) 1999-07-05 2002-01-04 Process for improving transport through customized semi-permeable barriers
US10/037,480 US7459171B2 (en) 1999-07-05 2002-01-04 Method for the improvement of transport across adaptable semi-permeable barriers
HK02106448.3A HK1046356A1 (en) 1999-07-05 2002-08-30 A method for the improvement of transport across adaptable semi-permeable barriers
US10/984,450 US7591949B2 (en) 1999-07-05 2004-11-08 Method for the improvement of transport across adaptable semi-permeable barriers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EPPCT/EP99/04659 1999-07-05
PCT/EP1999/004659 WO2001001962A1 (en) 1999-07-05 1999-07-05 A method for the improvement of transport across adaptable semi-permeable barriers

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/004659 Continuation WO2001001962A1 (en) 1999-07-05 1999-07-05 A method for the improvement of transport across adaptable semi-permeable barriers

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/037,480 Continuation US7459171B2 (en) 1999-07-05 2002-01-04 Method for the improvement of transport across adaptable semi-permeable barriers
US10/984,450 Continuation US7591949B2 (en) 1999-07-05 2004-11-08 Method for the improvement of transport across adaptable semi-permeable barriers

Publications (2)

Publication Number Publication Date
WO2001001963A1 WO2001001963A1 (en) 2001-01-11
WO2001001963A8 true WO2001001963A8 (en) 2001-04-19

Family

ID=8167360

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP1999/004659 WO2001001962A1 (en) 1999-07-05 1999-07-05 A method for the improvement of transport across adaptable semi-permeable barriers
PCT/EP2000/006367 WO2001001963A1 (en) 1999-07-05 2000-07-05 A method for the improvement of transport across adaptable semi-permeable barriers

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/004659 WO2001001962A1 (en) 1999-07-05 1999-07-05 A method for the improvement of transport across adaptable semi-permeable barriers

Country Status (18)

Country Link
US (2) US7459171B2 (en)
EP (1) EP1189598A1 (en)
JP (1) JP2003503442A (en)
KR (1) KR100852901B1 (en)
CN (1) CN1359288A (en)
AU (2) AU5409699A (en)
BR (1) BR0012178A (en)
CA (1) CA2375157A1 (en)
CZ (1) CZ200238A3 (en)
EE (1) EE200200008A (en)
HK (1) HK1046356A1 (en)
HR (1) HRP20010881A2 (en)
HU (1) HUP0201454A3 (en)
MX (1) MXPA02000053A (en)
NO (1) NO20020032L (en)
PL (1) PL352380A1 (en)
RU (1) RU2260445C2 (en)
WO (2) WO2001001962A1 (en)

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US9585817B2 (en) 2013-03-13 2017-03-07 Transdermal Biotechnology, Inc. Treatment of skin, including aging skin, to improve appearance

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