WO2000057932A3 - Nanocomposite surgical materials and method of producing them - Google Patents

Nanocomposite surgical materials and method of producing them Download PDF

Info

Publication number
WO2000057932A3
WO2000057932A3 PCT/US2000/008703 US0008703W WO0057932A3 WO 2000057932 A3 WO2000057932 A3 WO 2000057932A3 US 0008703 W US0008703 W US 0008703W WO 0057932 A3 WO0057932 A3 WO 0057932A3
Authority
WO
WIPO (PCT)
Prior art keywords
producing
nanometers
nanometer
surgical materials
nanocomposite
Prior art date
Application number
PCT/US2000/008703
Other languages
French (fr)
Other versions
WO2000057932A2 (en
Inventor
Anuj Bellare
Wolfgang Fitz
Andreas H Gomoll
Richard D Scott
Thomas S Thornhill
Original Assignee
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital filed Critical Brigham & Womens Hospital
Priority to CA002366377A priority Critical patent/CA2366377A1/en
Priority to JP2000607681A priority patent/JP2002539894A/en
Priority to EP00918531A priority patent/EP1163016A2/en
Priority to AU39327/00A priority patent/AU772507B2/en
Publication of WO2000057932A2 publication Critical patent/WO2000057932A2/en
Publication of WO2000057932A3 publication Critical patent/WO2000057932A3/en
Priority to HK02101222.6A priority patent/HK1039905A1/en
Priority to AU2004203446A priority patent/AU2004203446A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/12Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L31/125Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L31/128Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0089Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/446Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46

Abstract

Nanocomposite surgical materials, such as cements, having very fine heterogenous structure are formed by incorporating into a polymeric matrix a well dispersed solid, liquid or gaseous filler having an average mass diameter ranging from about 750 nanometers to about 1 nanometer. The average ligament thickness of the surgical composite cements ranges from about 750 nanometers to about 1 nanometer. Methods and apparatus for avoiding air contact during the preparation and transfer of a cement to an in vivo side are described.
PCT/US2000/008703 1999-03-31 2000-03-31 Nanocomposite surgical materials and method of producing them WO2000057932A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002366377A CA2366377A1 (en) 1999-03-31 2000-03-31 Nanocomposite surgical materials and method of producing them
JP2000607681A JP2002539894A (en) 1999-03-31 2000-03-31 Surgical nanocomposite and method for producing the same
EP00918531A EP1163016A2 (en) 1999-03-31 2000-03-31 Nanocomposite surgical materials and method of producing them
AU39327/00A AU772507B2 (en) 1999-03-31 2000-03-31 Nanocomposite surgical materials and method of producing them
HK02101222.6A HK1039905A1 (en) 1999-03-31 2002-02-20 Nanocomposite surgical materials and method of producing them
AU2004203446A AU2004203446A1 (en) 1999-03-31 2004-07-28 Nanocomposite surgical materials and method of producing them

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12724499P 1999-03-31 1999-03-31
US60/127,244 1999-03-31

Publications (2)

Publication Number Publication Date
WO2000057932A2 WO2000057932A2 (en) 2000-10-05
WO2000057932A3 true WO2000057932A3 (en) 2001-02-08

Family

ID=22429076

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/008703 WO2000057932A2 (en) 1999-03-31 2000-03-31 Nanocomposite surgical materials and method of producing them

Country Status (6)

Country Link
EP (1) EP1163016A2 (en)
JP (1) JP2002539894A (en)
AU (1) AU772507B2 (en)
CA (1) CA2366377A1 (en)
HK (1) HK1039905A1 (en)
WO (1) WO2000057932A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115742A1 (en) * 2001-02-22 2002-08-22 Trieu Hai H. Bioactive nanocomposites and methods for their use
SG130001A1 (en) 2001-09-14 2007-03-20 Sumitomo Chemical Co Process for producing resin composition and resin composition obtained according to said process
JP2005503865A (en) 2001-09-28 2005-02-10 ボストン サイエンティフィック リミテッド Medical device comprising nanomaterial and treatment method using the same
ES2288578T3 (en) * 2002-05-29 2008-01-16 Heraeus Kulzer Gmbh BONE CEMENT MIX AND X-RAY CONTRAST AGENT.
US7422713B2 (en) * 2003-10-14 2008-09-09 Hewlett-Packard Development Company, L.P. Hybrid organic-inorganic composition for solid freeform fabrication
US7455805B2 (en) * 2003-10-28 2008-11-25 Hewlett-Packard Development Company, L.P. Resin-modified inorganic phosphate cement for solid freeform fabrication
DE10357116A1 (en) 2003-12-06 2005-07-07 Solvay Barium Strontium Gmbh Deagglomerated barium sulfate
DE102005025719A1 (en) 2005-06-04 2006-12-07 Solvay Infra Bad Hönningen GmbH Process for producing a dispersion of deagglomerated barium sulfate in plastics or plastic precursors
EP2254609A2 (en) * 2008-02-22 2010-12-01 Maria Stromme Antipathogenic biomedical implants, methods and kits employing photocatalytically active material
DE102009006014A1 (en) * 2009-01-23 2010-08-05 Sachtleben Chemie Gmbh Polymer compositions with inorganic fillers and process for their preparation
KR101400712B1 (en) * 2012-11-30 2014-05-29 안동대학교 산학협력단 Three-dimensional scaffold composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500658A (en) * 1983-06-06 1985-02-19 Austenal International, Inc. Radiopaque acrylic resin
US4791150A (en) * 1985-10-01 1988-12-13 Bonar Cole Polymers Limited Composition for use in making bone cement
DE4229947A1 (en) * 1992-09-08 1994-03-10 Voco Gmbh Low shrinkage cement for medical and dental use - comprises oligomeric anhydride, poly:hydroxy cpd., reactive inorganic filler and hardener, with good adhesion and mechanical properties

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396476A (en) * 1979-02-01 1983-08-02 Dentsply Research & Development Corporation Blend of cross-linked polymer, swelling monomer and cross-linking agent and curing process
DE4029714A1 (en) * 1990-09-19 1992-03-26 Klaus Draenert Implant for e.g. stiffening bones and anchoring prostheses - consists of polymer and/or copolymer in which filler particles are at least partially embedded
US5334626A (en) * 1992-07-28 1994-08-02 Zimmer, Inc. Bone cement composition and method of manufacture

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500658A (en) * 1983-06-06 1985-02-19 Austenal International, Inc. Radiopaque acrylic resin
US4791150A (en) * 1985-10-01 1988-12-13 Bonar Cole Polymers Limited Composition for use in making bone cement
DE4229947A1 (en) * 1992-09-08 1994-03-10 Voco Gmbh Low shrinkage cement for medical and dental use - comprises oligomeric anhydride, poly:hydroxy cpd., reactive inorganic filler and hardener, with good adhesion and mechanical properties

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1163016A2 *

Also Published As

Publication number Publication date
WO2000057932A2 (en) 2000-10-05
JP2002539894A (en) 2002-11-26
AU3932700A (en) 2000-10-16
AU772507B2 (en) 2004-04-29
CA2366377A1 (en) 2000-10-05
EP1163016A2 (en) 2001-12-19
HK1039905A1 (en) 2002-05-17

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