WO2000043791A3 - Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases - Google Patents
Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases Download PDFInfo
- Publication number
- WO2000043791A3 WO2000043791A3 PCT/US2000/001997 US0001997W WO0043791A3 WO 2000043791 A3 WO2000043791 A3 WO 2000043791A3 US 0001997 W US0001997 W US 0001997W WO 0043791 A3 WO0043791 A3 WO 0043791A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- rapid
- species
- neurodegenerative diseases
- sensitive detection
- protein aggregation
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002361013A CA2361013A1 (en) | 1999-01-25 | 2000-01-25 | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
AU34741/00A AU3474100A (en) | 1999-01-25 | 2000-01-25 | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
JP2000595161A JP5122705B2 (en) | 1999-01-25 | 2000-01-25 | Rapid and sensitive detection of abnormal protein aggregation in neurodegenerative diseases |
EP00913266A EP1169646A2 (en) | 1999-01-25 | 2000-01-25 | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
US10/823,097 US20050112607A1 (en) | 1999-01-23 | 2004-04-13 | Rapid and sensitive detection of protein aggregation |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11712699P | 1999-01-25 | 1999-01-25 | |
US60/117,126 | 1999-01-25 | ||
US13228899P | 1999-05-03 | 1999-05-03 | |
US60/132,288 | 1999-05-03 | ||
US15593799P | 1999-09-24 | 1999-09-24 | |
US60/155,937 | 1999-09-24 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US60268900A Continuation-In-Part | 1999-01-23 | 2000-06-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2000043791A2 WO2000043791A2 (en) | 2000-07-27 |
WO2000043791A3 true WO2000043791A3 (en) | 2001-07-26 |
WO2000043791A9 WO2000043791A9 (en) | 2002-03-28 |
Family
ID=27381935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/001997 WO2000043791A2 (en) | 1999-01-23 | 2000-01-25 | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1169646A2 (en) |
JP (2) | JP5122705B2 (en) |
AU (1) | AU3474100A (en) |
CA (1) | CA2361013A1 (en) |
WO (1) | WO2000043791A2 (en) |
Cited By (2)
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US8975082B2 (en) | 2008-05-13 | 2015-03-10 | University Of Kansas | Metal abstraction peptide (MAP) tag and associated methods |
US9187735B2 (en) | 2012-06-01 | 2015-11-17 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
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EP1356296B1 (en) * | 2000-06-23 | 2016-04-20 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of protein aggregation |
WO2002029411A2 (en) | 2000-10-03 | 2002-04-11 | Minerva Biotechnologies Corporation | Magnetic in situ dilution |
AU2002219971A1 (en) | 2000-11-01 | 2002-05-15 | Minerva Biotechnologies Corporation | Detection of binding species with colloidal and non-colloidal structures |
WO2002061129A2 (en) | 2000-11-15 | 2002-08-08 | Minerva Biotechnologies Corporation | Oligonucleotide identifiers |
WO2002056022A2 (en) | 2000-11-27 | 2002-07-18 | Minerva Biotechnologies Corp | Diagnostics, drug screening and treatment for cancer |
US20030044843A1 (en) * | 2001-01-09 | 2003-03-06 | Mitsubishi Pharma Corporation | Novel proteome analysis method and devices therefor |
EP1395833B1 (en) | 2001-05-31 | 2013-02-27 | Adlyfe, Inc. | Misfolded protein sensor method |
US20050026165A1 (en) | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
EP1425016B1 (en) | 2001-09-05 | 2010-06-02 | Minerva Biotechnologies Corporation | Compositions and methods of treatment of cancer |
AU2003272924B2 (en) | 2002-10-04 | 2008-05-15 | Protosera Inc. | Plate for mass spectrometry, process for preparing the same and use thereof |
EP2363410B1 (en) | 2002-11-27 | 2017-10-11 | Minerva Biotechnologies Corporation | Isoforms of MUC1 |
AU2003300371A1 (en) | 2002-12-20 | 2004-07-22 | Minerva Biotechnologies Corporation | Optical devices and methods involving nanoparticles |
WO2005016127A2 (en) | 2003-08-13 | 2005-02-24 | Chiron Corporation | Prion-specific peptide reagents |
ATE442588T1 (en) | 2004-03-31 | 2009-09-15 | Anges Mg Inc | TEST METHOD FOR IDENTIFYING A CANDIDATE DRUG |
DE102004040119A1 (en) * | 2004-08-18 | 2006-04-27 | Heinrich-Heine-Universität Düsseldorf | Agent, useful for e.g. inactivating infectious prion and decontaminating device, instrument or appliance infected with prion, comprises a nano-particle |
NZ560535A (en) * | 2005-01-13 | 2011-01-28 | Novartis Vaccines & Diagnostic | Elisa assays using prion-specific peptide reagents |
ATE528649T1 (en) * | 2005-02-15 | 2011-10-15 | Adlyfe Inc | METHOD FOR DETECTING MISFOLDED PROTEINS AND PRIONS |
NZ566020A (en) | 2005-09-09 | 2012-08-31 | Novartis Ag | Prion-specific peptoid reagents |
EP2156181B1 (en) | 2006-07-28 | 2015-11-04 | Adlyfe, Inc. | Peptide probes for diagnostics and therapeutics |
KR20170110740A (en) | 2008-10-09 | 2017-10-11 | 미네르바 바이오테크놀로지 코포레이션 | Method for inducing pluripotency in cells |
WO2012017739A1 (en) * | 2010-07-31 | 2012-02-09 | エレコン科学株式会社 | Amyloid assay device and amyloid assay method |
KR101352849B1 (en) * | 2012-01-03 | 2014-01-21 | 주식회사 나노엔텍 | Method for Differentially Detecting Multimeric Form of Multimer-Forming Polypeptides |
JP2016520846A (en) * | 2013-06-06 | 2016-07-14 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | Reagents, methods and apparatus for preventing aggregation in particle-based tests for detection of multimeric target molecules |
EP3256494A4 (en) | 2015-02-10 | 2018-12-05 | Minerva Biotechnologies Corporation | Humanized anti-muc1* antibodies |
JP6630972B2 (en) * | 2015-03-24 | 2020-01-15 | 学校法人甲南学園 | Biosensor for electrochemical measurement of amyloid β peptide |
WO2017138696A1 (en) * | 2016-02-12 | 2017-08-17 | 주식회사 캔티스 | Detection method and electrochemical detection kit for aggregate form of protein, and diagnostic method and electrochemical diagnostic kit for diseases associated with abnormal protein aggregation by using same |
US11167283B2 (en) | 2018-05-04 | 2021-11-09 | University Of South Carolina | Dot blot box and use thereof |
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US4945045A (en) * | 1984-07-06 | 1990-07-31 | Serono Diagnostics Ltd. | Electrochemical methods of assay |
WO1994009364A1 (en) * | 1992-10-13 | 1994-04-28 | Duke University | Method of inhibiting binding of amyloid precursor protein to beta-amyloid protein |
WO1994010569A1 (en) * | 1992-10-26 | 1994-05-11 | Schenk Dale B | METHODS AND COMPOSITIONS FOR THE DETECTION OF SOLUBLE β-AMYLOID PEPTIDE |
WO1994013795A1 (en) * | 1992-12-14 | 1994-06-23 | N.V. Innogenetics S.A. | Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications |
EP0683234A1 (en) * | 1993-01-25 | 1995-11-22 | Takeda Chemical Industries, Ltd. | ANTIBODY AGAINST $g(b)-AMYLOID OR DERIVATIVE THEREOF AND USE THEREOF |
WO1997010505A1 (en) * | 1995-09-14 | 1997-03-20 | The Regents Of The University Of California | ANTIBODIES SPECIFIC FOR NATIVE PrP?Sc¿ |
WO1998031839A2 (en) * | 1997-01-21 | 1998-07-23 | President And Fellows Of Harvard College | Electronic-property probing of biological molecules at surfaces |
EP0861900A1 (en) * | 1997-02-21 | 1998-09-02 | Erziehungsdirektion Of The Canton Zurich | Immunological detection of prions |
EP0887645A1 (en) * | 1997-06-23 | 1998-12-30 | C.S.E.M. Centre Suisse D'electronique Et De Microtechnique Sa | Procedure and instrumentation for the ultrasensitive detection of prions, prion binding biomolecules and other biomolecules |
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-
2000
- 2000-01-25 EP EP00913266A patent/EP1169646A2/en not_active Withdrawn
- 2000-01-25 AU AU34741/00A patent/AU3474100A/en not_active Abandoned
- 2000-01-25 WO PCT/US2000/001997 patent/WO2000043791A2/en active Application Filing
- 2000-01-25 JP JP2000595161A patent/JP5122705B2/en not_active Expired - Fee Related
- 2000-01-25 CA CA002361013A patent/CA2361013A1/en not_active Abandoned
-
2012
- 2012-07-20 JP JP2012161791A patent/JP2012230124A/en active Pending
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US4945045A (en) * | 1984-07-06 | 1990-07-31 | Serono Diagnostics Ltd. | Electrochemical methods of assay |
WO1994009364A1 (en) * | 1992-10-13 | 1994-04-28 | Duke University | Method of inhibiting binding of amyloid precursor protein to beta-amyloid protein |
WO1994010569A1 (en) * | 1992-10-26 | 1994-05-11 | Schenk Dale B | METHODS AND COMPOSITIONS FOR THE DETECTION OF SOLUBLE β-AMYLOID PEPTIDE |
WO1994013795A1 (en) * | 1992-12-14 | 1994-06-23 | N.V. Innogenetics S.A. | Monoclonal antibodies directed against the microtubule-associated protein tau, hybridomas secreting these antibodies, antigen recognition by these monoclonal antibodies and their applications |
EP0683234A1 (en) * | 1993-01-25 | 1995-11-22 | Takeda Chemical Industries, Ltd. | ANTIBODY AGAINST $g(b)-AMYLOID OR DERIVATIVE THEREOF AND USE THEREOF |
WO1997010505A1 (en) * | 1995-09-14 | 1997-03-20 | The Regents Of The University Of California | ANTIBODIES SPECIFIC FOR NATIVE PrP?Sc¿ |
WO1998031839A2 (en) * | 1997-01-21 | 1998-07-23 | President And Fellows Of Harvard College | Electronic-property probing of biological molecules at surfaces |
EP0861900A1 (en) * | 1997-02-21 | 1998-09-02 | Erziehungsdirektion Of The Canton Zurich | Immunological detection of prions |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8975082B2 (en) | 2008-05-13 | 2015-03-10 | University Of Kansas | Metal abstraction peptide (MAP) tag and associated methods |
US9096652B2 (en) | 2008-05-13 | 2015-08-04 | University Of Kansas | Metal abstraction peptide (MAP) tag and associated methods |
US9187735B2 (en) | 2012-06-01 | 2015-11-17 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
Also Published As
Publication number | Publication date |
---|---|
WO2000043791A2 (en) | 2000-07-27 |
CA2361013A1 (en) | 2000-07-27 |
AU3474100A (en) | 2000-08-07 |
EP1169646A2 (en) | 2002-01-09 |
JP2002540383A (en) | 2002-11-26 |
WO2000043791A9 (en) | 2002-03-28 |
JP2012230124A (en) | 2012-11-22 |
JP5122705B2 (en) | 2013-01-16 |
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