WO2000023062A3 - Irrigation solution and method for inhibition of pain and inflammation - Google Patents
Irrigation solution and method for inhibition of pain and inflammation Download PDFInfo
- Publication number
- WO2000023062A3 WO2000023062A3 PCT/US1999/024558 US9924558W WO0023062A3 WO 2000023062 A3 WO2000023062 A3 WO 2000023062A3 US 9924558 W US9924558 W US 9924558W WO 0023062 A3 WO0023062 A3 WO 0023062A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- antagonist
- pain
- solution
- inflammation
- agonist
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99970596A EP1434573A2 (en) | 1998-10-20 | 1999-10-20 | Irrigation solution and method for inhibition of pain and inflammation |
AU12149/00A AU1214900A (en) | 1998-10-20 | 1999-10-20 | Irrigation solution and method for inhibition of pain and inflammation |
US09/839,633 US7091181B2 (en) | 1994-12-12 | 2001-04-20 | Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors |
US09/839,633 US20020028798A1 (en) | 1995-12-12 | 2001-04-20 | Irrigation solution and method for inhibition of pain and inflammation |
US11/410,406 US20060205657A1 (en) | 1994-12-12 | 2006-04-24 | Irrigation solution and method for inhibition of pain and inflammation |
US11/409,919 US20060229588A1 (en) | 1994-12-12 | 2006-04-24 | Irrigation solution and method for inhibition of pain and inflammation |
US11/410,407 US20060205658A1 (en) | 1994-12-12 | 2006-04-24 | Irrigation solution and method for inhibition of pain and inflammation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10504498P | 1998-10-20 | 1998-10-20 | |
US60/105,044 | 1998-10-20 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/024557 Continuation-In-Part WO2000023061A2 (en) | 1994-12-12 | 1999-10-20 | Irrigation solution and method for inhibition of pain and inflammation |
Related Child Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/024625 Continuation-In-Part WO2000023072A1 (en) | 1994-12-12 | 1999-10-20 | Irrigation solution containing mapk inhibitors and their use for treating pain and inflammation |
US09/839,633 Continuation-In-Part US20020028798A1 (en) | 1994-12-12 | 2001-04-20 | Irrigation solution and method for inhibition of pain and inflammation |
US11/410,406 Continuation-In-Part US20060205657A1 (en) | 1994-12-12 | 2006-04-24 | Irrigation solution and method for inhibition of pain and inflammation |
US11/409,919 Continuation-In-Part US20060229588A1 (en) | 1994-12-12 | 2006-04-24 | Irrigation solution and method for inhibition of pain and inflammation |
US11/410,407 Continuation-In-Part US20060205658A1 (en) | 1994-12-12 | 2006-04-24 | Irrigation solution and method for inhibition of pain and inflammation |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000023062A2 WO2000023062A2 (en) | 2000-04-27 |
WO2000023062A3 true WO2000023062A3 (en) | 2000-07-27 |
Family
ID=22303751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/024558 WO2000023062A2 (en) | 1994-12-12 | 1999-10-20 | Irrigation solution and method for inhibition of pain and inflammation |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1434573A2 (en) |
AU (1) | AU1214900A (en) |
WO (1) | WO2000023062A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8188043B2 (en) | 1999-07-28 | 2012-05-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine in therapeutic angiogenesis and vasculogenesis |
US7838539B2 (en) | 1999-07-28 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Nicotine receptor agonists in stem cell and progenitor cell recruitment |
BR0012793A (en) * | 1999-07-28 | 2002-04-30 | Univ Leland Stanford Junior | Methods for inducing angiogenesis by administering nicotine or another nicotine receptor agonist |
US6720340B1 (en) * | 1999-07-28 | 2004-04-13 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine receptor agonists in stem cell and progenitor cell recruitment |
CA2341952A1 (en) * | 2001-03-23 | 2002-09-23 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases |
US8039459B2 (en) | 2004-07-15 | 2011-10-18 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
US8557804B2 (en) | 2002-03-25 | 2013-10-15 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
CN1684701B (en) | 2002-07-30 | 2012-10-17 | 奥默罗斯公司 | Ophthalmologic irrigation solutions and method |
US7238715B2 (en) * | 2002-12-06 | 2007-07-03 | The Feinstein Institute For Medical Research | Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists |
MX2009007916A (en) | 2007-01-24 | 2009-07-31 | Glaxo Group Ltd | Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1. |
AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Surgical (Ireland) Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
TWI705812B (en) | 2014-12-01 | 2020-10-01 | 奥默羅斯公司 | Anti-inflammatory and mydriatic intracameral solutions for inhibition of postoperative ocular inflammatory conditions |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5820583A (en) * | 1995-12-12 | 1998-10-13 | Omeros Medical Systems, Inc. | Surgical irrigation solution and method for inhibition of pain and inflammation |
-
1999
- 1999-10-20 EP EP99970596A patent/EP1434573A2/en not_active Withdrawn
- 1999-10-20 AU AU12149/00A patent/AU1214900A/en not_active Abandoned
- 1999-10-20 WO PCT/US1999/024558 patent/WO2000023062A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5820583A (en) * | 1995-12-12 | 1998-10-13 | Omeros Medical Systems, Inc. | Surgical irrigation solution and method for inhibition of pain and inflammation |
Non-Patent Citations (6)
Title |
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BONDAREV V I ET AL: "[Disorders of immunoreactivity in acute cholecystitis in middle-aged and elderly patients and their correction in preventing postoperative complications]. Narusheniia immunoreaktivnosti pri ostrom kholetsistite u bol'nykh pozhilogo i starcheskogo vozrasta i ikh korrektsiia v profilatike posleoperats", KLINICHESKAIA KHIRURGIIA, (1990) (9) 27-9., XP002137213 * |
CHIARI A, EISENACH J C: "ANTINOCICEPTIVE EFFECTS OF RJR 2403, A SELECTIVE NICOTINIC AGONIST, IN MALE AND FEMALE RATS.", FASEB JOURNAL, vol. 12, no. 4 PART 1, SUPP. [S], 17 March 1998 (1998-03-17), pages 920, XP000906769 * |
DECKER ET AL: "Antinociceptive effects of the novel neuronal nicotinic acetylcholine receptor agonist, ABT-594, in mice", EUROPEAN JOURNAL OF PHARMACOLOGY,NL,AMSTERDAM, vol. 346, no. 1, 3 April 1998 (1998-04-03), pages 23 - 33-33, XP002110643, ISSN: 0014-2999 * |
DONNELLY-ROBERTS ET AL: "ABT-594: a novel, orally effective analgesic acting via neuronal nicotinic acetylcholine receptors", JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS,US,AMERICAN SOCIETY FOR PHARMACOLOGY AND, vol. 285, no. 2, May 1998 (1998-05-01), pages 777 - 786-786, XP002105019, ISSN: 0022-3565 * |
HOLLADAY ET AL: "Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery", JOURNAL OF MEDICINAL CHEMISTRY,US,AMERICAN CHEMICAL SOCIETY. WASHINGTON, vol. 40, no. 26, 19 December 1997 (1997-12-19), pages 4169 - 4194-4194, XP002124847, ISSN: 0022-2623 * |
ZHANG, XIAO. GONG, ZE-HUI. FASTH, KARL JOHAN. LANGSTROM, BENGT. NORDBER AGNETA: "INTERACTION OF THE NICOTINIC AGONIST (R,S)-3-PYRIDYL-1-METHYL-2-(3-PYRIDYL)-AZETIDINE (MPA) WITH NICOTINIC ACETYLCHOLINE RECEPTOR SUBTYPES EXPRESSED IN CELL LINES AND RAT CORTEX.", NEUROCHEM. INT., vol. 32, no. 5-6, 1998, pages 435 - 441, XP000905243 * |
Also Published As
Publication number | Publication date |
---|---|
WO2000023062A2 (en) | 2000-04-27 |
EP1434573A2 (en) | 2004-07-07 |
AU1214900A (en) | 2000-05-08 |
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